Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MATR3P3
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:181146232-181146884  UCSC
Coordinates (T2T) chr3:183947933-183948585  UCSC
Coordinates (hg19) chr3:180864020-180864672  UCSC
Strand +
Parental Sequence NM_199189.3
Parental seq. overlap 636 bp
Parental seq. overlap (%) 12.1%
Genomic Region Intergenic
Retrocopy Summary MATR3P3, located on chr3:181146232-181146884, is a retrocopy of the parental gene MATR3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MATR3
Full Name matrin 3
Also known as ALS21|MPD2|VCPDM
Coordinate chr5:139274101-139331677
Strand +
Gene summary This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. [provided by RefSeq, Aug 2013]

Homology

Species Scientific Name Retrocopy
Gorilla Gorilla gorilla MATR3P2
Orangutan Pongo abelii MATR3P2
Gibbon Nomascus leucogenys MATR3P1
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MATR3P3
AGACTATACAATCCCAGATGAGTATAGAATTGGACCATATCAGCCCAATGTTCCTGTTGGTATGGACTATGTGATACCTAAAACAGGGTTTTACGGTAAGCTGTGTTCATTCTTTTATACAAATGAAGAAGTTGCAAAGAATACTCATTGCAGCAGCCTTCCTCATTATCAGAAATTAAATAAATTTCTGAATAAATTGGCAGAAGAATGCAGACAGAAGAAGAAAACTTAAGAAGTGCAAGTAGATTTAATGATTTCAAAGAAAATAGTGGTTCTTTGTTTTTAATGTTAACCTTTTTTAAATACAATACTGATAGAAGAAAACTATTGTACTCTTTTGTTTTAGTGGAGAAATAATAGATGTCTGTTCATGTGTTAAATGTTATAGCAAAAAAAAAAATACACATATGGTTAAGTTAATGAATAGTTTTTGTTTTATCAGAATGGCAACGGACAGAAGTACTTTGCAGAGATTGACTTCCTAAGCTACTTAAGACAACTTGCACCACTAAGAAAAAAATGTAGAACCATTTGGAAAAATGAAATTTAGTAGTTCCAAGTTTCAAAGAAATGTCAACATTTTATTCCATTCAATAAAGAACAAAACCAATAGTATTTTTATTACTTTCATCTGAAACATTCCATGTTTTAAT
>NM_199189.3
CCCTTTCCCCTCCGGCCTCTGCCGGTGCTGCTGCGCCCTGCGGAGCTCCGAACACGTGCGCAGAGGCTGGCTGTGGCAGATGCAACTGCAGGATGACTTGAAAGTAGGGCATCCTTCACCCATCTGAAGGGAGGAAATAGTGGCAGGTGACAGTCTGCATGTGCAGTTTTCAGATGCCTTCACCTGAATGACATCTACCTCCATCAGGACCCCAGATGTCTGACAGCCCTGTGTGACACCAAGATAAGTAACAGTTGTCTGCTGGTTCTCAGCTTGAAGAAGATTCTGCAGTCCTTATTGATCCTTTTTCTTGGCGTTACCATTTTTGAAGCAAAGTTAACCTAGCTTTCTAGTTTGAGCTTTCTTTTTGGCCGTCTTTAAAAAAATTTTTTTTTTTAATCTATAAAATAGACAAGAGCTAGTTCTACAATGTCCAAGTCATTCCAGCAGTCATCTCTCAGTAGGGACTCACAGGGTCATGGGCGTGACCTGTCTGCGGCAGGAATAGGCCTTCTTGCTGCTGCTACCCAGTCTTTAAGTATGCCAGCATCTCTTGGAAGGATGAACCAGGGTACTGCACGCCTTGCTAGTTTAATGAATCTTGGAATGAGTTCTTCATTGAATCAACAAGGAGCTCATAGTGCACTGTCTTCTGCTAGTACTTCTTCCCATAATTTGCAGTCTATATTTAACATTGGAAGTAGAGGTCCACTCCCTTTATCTTCTCAACACCGTGGAGATGCAGACCAGGCCAGTAACATTTTGGCCAGCTTTGGTCTGTCTGCTAGAGACTTAGATGAACTGAGTCGTTATCCAGAGGACAAGATTACTCCTGAGAATTTGCCCCAAATCCTTCTACAGCTTAAAAGGAGGAGAACTGAAGAAGGCCCTACCTTGAGTTATGGTAGAGATGGCAGATCTGCTACACGGGAGCCACCATACAGAGTACCTAGGGATGATTGGGAAGAAAAAAGGCACTTTAGAAGAGATAGTTTTGATGATCGTGGTCCTAGTCTCAACCCAGTGCTTGATTATGACCATGGAAGTCGTTCTCAAGAATCTGGTTATTATGACAGAATGGATTATGAAGATGACAGATTAAGAGATGGAGAAAGGTGTAGGGATGATTCTTTTTTTGGTGAGACCTCGCATAACTATCATAAATTTGACAGTGAGTATGAGAGAATGGGACGTGGTCCTGGCCCCTTACAAGAGAGATCTCTCTTTGAGAAAAAGAGAGGCGCTCCTCCAAGTAGCAATATTGAAGACTTCCATGGACTCTTACCGAAGGGTTATCCCCATCTGTGCTCTATATGTGATTTGCCAGTTCATTCTAATAAGGAGTGGAGTCAACATATCAATGGAGCAAGTCACAGTCGTCGATGCCAGCTTCTTCTTGAAATCTACCCAGAATGGAATCCTGACAATGATACAGGACACACAATGGGTGATCCATTCATGTTGCAGCAGTCTACAAATCCAGCACCAGGAATTCTGGGACCTCCACCTCCCTCATTTCATCTTGGGGGACCAGCAGTTGGACCAAGAGGAAATCTGGGTGCTGGAAATGGAAACCTGCAAGGACCTAGACACATGCAGAAAGGCAGAGTGGAAACTAGCAGAGTTGTTCACATCATGGATTTTCAACGAGGGAAAAACTTGAGATACCAGCTATTACAGCTGGTAGAACCATTTGGAGTCATTTCAAATCATCTGATTCTAAATAAAATTAATGAGGCATTTATTGAAATGGCAACCACAGAGGATGCTCAGGCCGCAGTGGATTATTACACAACCACACCAGCGTTAGTATTTGGCAAGCCAGTGAGAGTTCATTTATCCCAGAAGTATAAAAGAATAAAGAAACCTGAAGGAAAGCCAGATCAGAAGTTTGATCAAAAGCAAGAGCTTGGACGTGTGATACATCTCAGCAATTTGCCGCATTCTGGCTATTCTGATAGTGCTGTTCTCAAGCTTGCTGAGCCTTATGGGAAAATAAAGAATTACATATTGATGAGGATGAAAAGTCAGGCTTTTATTGAGATGGAGACAAGAGAAGATGCAATGGCAATGGTTGACCATTGTTTGAAAAAAGCCCTTTGGTTTCAGGGGAGATGTGTGAAGGTTGACCTGTCTGAGAAATATAAAAAACTGGTTCTGAGGATTCCAAACAGAGGCATTGATTTACTGAAAAAAGATAAATCCCGAAAAAGATCTTACTCTCCAGATGGCAAAGAATCTCCAAGTGATAAGAAATCCAAAACTGATGGTTCCCAGAAGACTGAGAGTTCAACCGAAGGTAAAGAACAAGAAGAGAAGTCCGGTGAAGATGGTGAGAAAGACACAAAGGATGACCAGACAGAGCAGGAACCTAATATGCTTCTTGAATCTGAAGATGAGCTACTTGTAGATGAAGAAGAAGCAGCAGCACTGCTAGAAAGTGGCAGTTCAGTGGGAGACGAGACCGATCTTGCTAATTTAGGTGATGTGGCTTCTGATGGGAAAAAGGAACCATCAGATAAAGCTGTGAAAAAAGATGGAAGTGCTTCAGCAGCAGCAAAGAAAAAGCTTAAAAAGGTGGACAAGATCGAGGAACTTGATCAAGAAAACGAAGCAGCGTTGGAAAATGGAATTAAAAATGAGGAAAACACAGAACCAGGTGCTGAATCTTCTGAGAACGCTGATGATCCCAACAAAGATACAAGTGAAAACGCAGATGGTCAAAGTGATGAGAACAAGGACGACTATACAATCCCAGATGAGTATAGAATTGGACCATATCAGCCCAATGTTCCTGTTGGTATAGACTATGTGATACCTAAAACAGGGTTTTACTGTAAGCTGTGTTCACTCTTTTATACAAATGAAGAAGTTGCAAAGAATACTCATTGCAGCAGCCTTCCTCATTATCAGAAATTAAAGAAATTTCTGAATAAATTGGCAGAAGAACGCAGACAGAAGAAGGAAACTTAAGATGTGCAAGGAGATTTAATGATTTCAAAGAAAATAATGGTTCTTTGTTTTTAATGTTAACCTTTTTTAAATACAATACTGATAGTTAGAAGAAAACTATTGTACTCTTTTGTTTTAGTGGAGAAATAATAGATGTCTGTTCATGTGTTAAGTGTTATAGCAAAAAAAATACACATATGGTTAAGTTAATGAATAGTTTTTGTTTTATCAGAATGGCAACAGACAGAAGTACTTTGTAGAGATTGACTTCCTAAGCTACTTAAGACAACTTGCACCACTAAGAAAAAAATGTAGAACCATTTGGAAAAATGAAATTTAGTAGTTCCAAGTTTCAAAGAAATGTCAACATTTTATTCCATTCAATAAAGAACAAAACCAATAGTGTTTTTATTACTTTCATCTGAAACATTCCATGTTTTAATCTGAGCCTTGCAGACTTTCATTTGGAGTTTGAACCCGTTTTGGTTGCATTTCATTTTTGGAGAACTTAATTAACGTGAGATTGGCAATTGAAATGCAGGTGCAGTTTTCTGTTAATGTCATGCTGTTGTTTAGGTAATAAGAAATATTAAGTAATTGGCTTTAGATTTTGTAATTTTTTTCCCTGAGTTCCTGCTAGATTTCGTATTCTAGTAGTCAATGTATTTTCAGTGAAATGCAAAAATATTCCCGTTATCTTTGACCAGTATTAATTTTTGAGATCTTACTGCTTGTCACTTGAATCCCGTGATTGTCATACATCTCTGGTATAAGCAACATTTGATTTTTGAAGTGTGTAGACCATCTCTTCATATTTTCAAGATGTAATTTTACATTTCTGCATTTTTAAAACAGTTTGGCCATAATCCTAGATGCACGCTTCTAATTCATGTACCTGCACATGTGACCTTTGTGAACAGAAATTTGCATGTATAATTTGTGTTTACTTGTAACTTTCTGGTTATATACTGCTTATATCTGTGGATTCAAGTTACTGAAGTGAATACCAATAAAAAGAAAACCCTAGGCCATGTTAATTGGTTATACATGTTTGGAATGTTAACCAACGTATTTGTCAGTTGTGGTTTTTATTCGCTCTTAAACTTTGTGCATGCTTTAACAATTTATTACTTTTAAATCTAGAGTGAATTCTAAAGACTGCCGCTAAAGATCTGAGTTTTAAAAATGTTGTTGCTGGTGGATTTCTTGTTCCTGTTACATAACTAAAAGTGAGGCCATTTGTGGTTTTTAAAAACCTTATGAATTAAAAATGCTACAGGTGAACAAACAGAAGCTTATGTTTAGAGATATTGATGACTTAACAGTACAATTGGAAGTAATACGGATGAGCAAGAATTAGTTCTGCAGCTTTTCAAAATAATTACGTAGAGACTCTTGGTATATTGGATTATCTGTTGTAAACAAtttttttttcttccctgacacagggtctcactctgtcacccagactggagtgcagtggcacagttctctgcaacctcagcctttgggctcaaatgaccctcctacctcagtctcctgagtagctgggactacaggctcatgccactatacctggctagtttttggtttttttgtatagatggggctttgccatgttgcccaggttgatcttgaattcctgggcccaagtgatctgctcgcttcagcctcccaaagtgctgggactgtaggcatgagccaccatccctggccAAGAAACAAAGTTTTAATTTCAAAAAAATCTACAAAAACAGGATAGGCATTGTCTTTCAAATGTTCAGACCCCAGTTTATTAAAGGATACTTCAAATAGTTGGCTAAATTTTATGATCTCTCCCGTTGAAAAGTAGGTGATGATTTTAATGTGACATGCACAAAAAATCCTTGCCAGTTTACTTCTGCAATTTAATTTTAGCCTTTACTAATTACCCACTTCTGTTTAATTCCAATTTTTAACAGCAGGTACATAAAGCATTATGTGCACAATGGAGTTCTTCAGTGTTTCCTTTCAGTGATGGCTTTTTCATAGCTTCAACTTTGTTGGATTTAGCAAGTTGAAGGAAAGAATGCTATGTTTTTAATACCTACATTTGAGAGCATTTAGAAATCAGAAATTATAATAAGCTGTTAGTGATAAATCTGTAACAGCCCTTCGATTACGAGAAAACCTCTTTTTAGTAGGAATGTTTCCACTCATGTTTGCTGTAAAGTTTAAGAACATTTTTCCTACGGCTATGTCAGCCCTTAGTTTAATCTTACATTATCCTACAAAAGTGAATGAAACTTCTAGAAGTACCTTGA

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