Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TVP23BP3
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:183462680-183462980  UCSC
Coordinates (T2T) chr3:186270100-186270400  UCSC
Coordinates (hg19) chr3:183180468-183180768  UCSC
Strand -
Parental Sequence NM_001316920.1
Parental seq. overlap 241 bp
Parental seq. overlap (%) 13.6%
Genomic Region Intergenic
Retrocopy Summary TVP23BP3, located on chr3:183462680-183462980, is a retrocopy of the parental gene TVP23B. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TVP23B
Full Name trans-golgi network vesicle protein 23 homolog B
Also known as CGI-148|FAM18B|FAM18B1|NPD008|YDR084C
Coordinate chr17:18781183-18806714
Strand +
Gene summary Predicted to be involved in protein secretion and vesicle-mediated transport. Predicted to be integral component of membrane. Predicted to be integral component of Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TVP23BP2
Bonobo Pan paniscus CDRT4P2
Green monkey Chlorocebus sabaeus TVP23BP3
Crab-eating macaque Macaca fascicularis LOC102138187P1
Rhesus Macaca mulatta TVP23BP1
Baboon Papio anubis TVP23BP1
Golden snub-nosed monkey Rhinopithecus roxellana LOC104659611P1
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TVP23BP3
TGTGGTGCAATAAGGTGCCAAGCTATCTGGCTACATCAGGTGTAAAATGGGTAGCAGAAAGAATTTAACCAGCACGGCTATGTCTTATCTTGGAAAGTTCATAGGACAAAATATTGGAGATAATCAGACTCCCTGAGTAGAAAGAGAAAACATACATGTTCTGTTACATCAGGGAGCAACTAACAAGATTCTTGACTCTGAACCTTTTAGAGTTCAGTACATGCTGCAAATAAGTTGGATTTGTTTTTCCACTGACAATTTTTATTTTAAAAGAGGAAAAGCTGTGTTCATACTAAGTTTG
>NM_001316920.1
GACTTGGGAGAGAACAGGATAGTAATGATGACACTGAAGATGTTTCACTGTTTGATGCGGAAGAGGAGACGACTAATAGACCAAGAAAAGCCAAAATCAGACATCCAGTAGCATCGTTTTTCCACTTATTCTTTCGAGTCAGTGCAATCATCGTCTATCTTCTCTGTGGGTTGCTCAGCAGCAGCTTTATTACCTGTATGGTGACAATTATCTTGTTGTTGTCGTGTGACTTTTGGGCAGTGAAGAATGTCACAGGTAGACTAATGGTTGGCCTACGTTGGTGGAATCACATTGATGAAGATGGAAAGAGCCATTGGGTGTTTGAATCTAGAAAGGAGTCCTCTCAAGAGAATAAAACTGTGTCAGAGGCTGAATCAAGAATCTTTTGGTTGGGACTTATTGCCTGTCCAGTACTGTGGGTGATATTTGCTTTTAGTGCACTCTTCTCCTTCAGAGTAAAGTGGTTGGCGGTGGTTATCATGGGTGTGGTGCTACAAGGTGCCAACCTGTATGGTTACATCAGGTGTAAGGTGCGCAGCAGAAAGCATTTAACCAGCATGGCTACTTCATATTTTGGAAAGCAGTTTTTAAGACAAAACACTGGAGATGATCAGACTTCCTGAATAGAGAAAGCTTATGTGCTTTGTTACATTGGGGAACAACTGAAGAGATTCTTGACTCAACCTTTTAGAGCTTAGTCCATGTTGCAACGAGGAGTGTTGGCTTTGTTTTTCCACTTAAAAACTTTATTTATAAAAAGGAAAAGTAGTTTTCATATTAAGTTTTTATTTCCTTTCCAGCAGTTGGGGCTAGAAAGTATGTGTTGGCACTAGAAACATTGTCAAGATTTGTTCTGTGGTGTAGGTATGCACATTCCATAGGTATGCACACGGCCATGTAATATCAGTATATCCCAAGTTAATGAAAGTGTTCATTTACATAGGTAATGGAGACCTTTGCATTTTGATCCATAGAACATAGGAGGATGTTCTTAGTCTGTCTCAAAGCTCTATATGTTTACATATTATTTCTGTAGATTGTTTTCAGGAGAAAGTTTTGCTTCTATGGTAAGAGTGAGCACTTTGGCTTATGTATAAGTTAGAAATAATTGTTAGTTTTTAATATGCACTTCGTGGGGAAATTTCTTAGACGTATGCAAGCAAGTGAAAACAATTAGGGCCAGTGGTATTAACTACTTTATAAAATTTTATTTTTGTTTGTAAGAAGTCATCTATTTAAGGCCCAGTTAATATAAGTGGAATCATCATAGTTTAAGGAATACCCAGAGATTGCTGCTGTTCTATTTATTTTACAGAAAGGATAGCTAGATTGAAAGCTCTTCAGTGGACCTTGAGCTAATAGATCTTTTACCACTAAAAGAGCATTATTCTCATGTCATAATGAGAATAATAATTTACATACTTGGCATAATAAATGCCTAAAAGACATTTTATTTTCTGAATCTATTTTTTTCTTGCTATAATGGGGATATTGTAAATTATGCATTTGTATTAATGGTATTTCTTAAAGCAATCTATGTAACTGTAAATTAAACCAATCTACAAACTATTGTAGGCATCTGTAAATTCTGTTGTAGGTATTATAAACTTTGTTGAAGTCTTAATCAGCAGATTATGTTGTGAATATATTTGTACATTGTTAAAATAGTTTTTAAGATTATTTGTTTAATTGAATAAGTGTCTTATTGGAGTGATAGCTTTGAAGGTGCAAAActttatatttgtataaaattctactatttacaaggc

Publications

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