Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name VENTXP7
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:21405680-21406660  UCSC
Coordinates (T2T) chr3:21416136-21417118  UCSC
Coordinates (hg19) chr3:21447172-21448152  UCSC
Strand +
Parental Sequence NM_014468.4
Parental seq. overlap 868 bp
Parental seq. overlap (%) 35.1%
Genomic Region Intergenic
Retrocopy Summary VENTXP7, located on chr3:21405680-21406660, is a retrocopy of the parental gene VENTX. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name VENTX
Full Name VENT homeobox
Also known as HPX42B|NA88A|VENTX2
Coordinate chr10:133237855-133241928
Strand +
Gene summary This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Orangutan Pongo abelii VENTXP2
Gibbon Nomascus leucogenys VENTXP1
Green monkey Chlorocebus sabaeus VENTXP5
Crab-eating macaque Macaca fascicularis VENTXP1
Rhesus Macaca mulatta VENTXP2
Baboon Papio anubis VENTXP1
Golden snub-nosed monkey Rhinopithecus roxellana VENTXP2
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>VENTXP7
gATCCTGCGCCTGGCCAGCCCCGCCCGACCTTCCCTCCGGCCCACCTGACCGCCATGTGTCTCTCCTCCTCCCCACCTCGTGGCTGGCAGCAGCCCTCCAGCTTTGGCTCCGTGGACTGGCTCTGCCTGAGCAGCTGCTCAGGGTCGACCCACACCCCCAGGCCTGCCGACGTCTCCCCCGGGAGCCTCCCTGGCCCGGGCCAGACGTTCGGCACCCGGGAGCCCCCTCAGGCTGTCAGTACCAAGGAGGCTAGCTCGTCAAATCTGCATGCGCCGGAGAGGACTGTGGCTGGGTTGAGTAAGGAGCCAAACCCCTAGCTGGCTCCCGGTGTCCGCACAGCCTTCACCACGGAGCAGGTCCGTGCCTTGGAGGGCGTCTTCCGGCACCACCAGTACCTGGGCCCTCTGGAGCGGAATTGGCTGGCCAGGGAGATGCAGCTCTCAGAGGTCCAGATAAAAACCTGGTTTCAAAATCGCCGGATGAAACACAAACGGCAAATGCAGGACTCCCAGCTAAACGGCCCCTTATCGGGGTCTCTCCACGGGCCCCCTGCTTTCCACTCACCATCTTCTGGCCTTGCCAATGGCCTGCAGCTGCTGTGCCCTTGGGCACCCCTGCCTGGGTCCCCTGGCTGCCCCTTGGCTCCTTCTGGGGTCTCCGACAAATGGATCAAGAGGCCCTGGCCTCTTCGTGGGCTTCCTGCTGCGGGCAGCCTCTGGCATACCACCCCCCACGCCCAGGAAGTGGTGCGCATAAGCTGGGACCAGCCCTGTCCACGGGGCCCCGGGGCCTGTGTGCTCTGCCAGAGACAGGGGATGCATTTGAGGAAACGCCTCCGACTACATGCCTCCCACACAAGCGGTCTGTGCAGATCGCATCTGACGCCTACCCGGAGGACTCAGCTGTTCTGTTTACATCGTGGCGGCACCTCTCACCCTGACCCTCGCAAAGGTTCTGGAGATTTCTGGAGAATATAT
>NM_014468.4
GAGGTGGATCCTGCGCCTGGCCAGCCCCGCCTGGCCTTCCCTCCGGCCCACCTGGCCGCCATGCGCCTCTCCTCCTCCCCACCTCGTGGCCCGCAGCAGCTCTCCAGCTTTGGCTCCGTGGACTGGCTCTCCCAGAGCAGCTGCTCAGGGCCGACCCACACCCCCAGGCCTGCCGACTTCTCCCTGGGGAGCCTCCCTGGCCCAGGCCAGACATCCGGCGCCCGGGAGCCCCCTCAGGCCGTCAGCATCAAGGAGGCCGCCGGGTCCTCAAATCTGCCTGCGCCGGAGAGGACCATGGCCGGGTTGAGTAAGGAGCCAAATACCTTGCGGGCCCCCCGTGTCCGCACAGCCTTCACCATGGAGCAGGTCCGCACCTTGGAGGGCGTCTTCCAGCACCACCAGTACCTGAGCCCTCTGGAGCGGAAGAGGCTGGCCAGGGAGATGCAGCTCTCAGAGGTCCAGATAAAAACCTGGTTTCAGAATCGCCGCATGAAACACAAACGGCAAATGCAGGACCCCCAGCTGCACAGCCCCTTCTCGGGGTCTCTCCATGCGCCCCCAGCTTTCTACTCAACGTCTTCTGGCCTTGCCAATGGCCTGCAGCTGCTGTGCCCTTGGGCACCCCTGTCCGGGCCCCAGGCTCTGATGCTGCCCCCTGGCTCCTTCTGGGGTCTCTGCCAAGTGGCACAAGAGGCCCTGGCATCTGCGGGAGCTTCCTGCTGCGGGCAGCCTCTGGCGTCCCACCCCCCTACCCCAGGCCGGCCTTCGCTGGGACCAGCCCTGTCCACGGGGCCCCGGGGCCTGTGTGCTATGCCACAGACGGGGGATGCATTTTGAGGAGGCACCTCTGACTCCCACACTCGCGGTCTTGCTGATCGCACCTGGCTCCTACCTGGAGGACTCAGTTGTTCTGTTTACATCCTGGTGGCACCTCTCACCCTGACCCACACAAAGGTTCTGGAGATTACTGGAGAatatatataaatatatatatgtacgtatatatgtaaatacacatatacgtatatataaatatatatatacatatgtgtgtgtatatatatatatatttttttttttttttttttttttgagacggagtgttgctctgtcacccaggctggagtgcaatgacgcaatctcggctcactgcaacctccgcctcctgggttcaagcgattctccagcctcagcctcccgagtagctgggattacagacacccgccaccacgcccggctaattttttctatttttagtagaaatggggtttcaccatgttagccaggctggtctcaaactcctgaccctgtgatccgcccgcctcggcctcccaaagtgctgggattacaggcatgagccactgcacccggccctgagaatatatttatTAAAGCCACCTCTTCACTGAAAGTTACCGAAAGAGTCGGTTTAGGAAGGAAACGAAGGGTCAGTGAACAGAGTCAAATGCAGAAGTGGGCTTGTCATGGGTAGGGCTTTCGGCGTACGATAAAAGGATCATTTGTTTTTTAAAAGGGGTTGGAAAAACTGGTTTTCCAGTTGGAAACAGTAAAGGTTGTAAGCTTTGTGTGTACAAAAGAAAACAGGGAATGCAGGTGTGTTTATAGCGTTGTGGTTCAAGTCCCTCTTAACAAGAACTCCAAAGCTGGAAAGCAGGAGGGAACAAAGGTGAACATGAAGGCGAGGATGCTGGGGCCCTGCAGTGCGCTCTAGGCTGTGCGTGAGCCGGGACTGTACCCACAGCTTGCTGAGGGCTGCTCTTCTTGGGCCAGGGAAAGCAGGGCAGCCGGGACCTGCGGCTGTGCCTGGACTGAAGCTGTCCCGCAGGTCCCCACCCTCCAACACGTGCTCACCTGTCCCCCTGCTCGCAGCAGCCTCGGGACAAAACAATGACTCAAGGACAGCACTTCTTGCAGAAGGTCTGGAAGTGCCCAGAATGGGAGGCACGGAAGCCCCTCCCGGGGAGGACTCCCGCGTTGATGGACCGTTCTTGGTGCAGACTCCTGACTGCGTGCATGAAACCTGAGACAAGTGCAATTCCTTCCATGTCGCCCCAGAGTGCCCAGGAGGCAGGCAGTGCGGGGTGCCCAGGCAGACGGGTTCAGCCTGCAGAACTGGAGGCGACCTGTGAAACCCACCCGGGCACCCCAACAGGAACAGAAGCGTGGTCCTGCGGCTGCGTCCCCAGCGAGTTTCACTTTCCCCTTGCTCGTTTCTCCCTTGTTGTAAGTGTTTACAACTGGCATGTGCTTTTAAACGTCAGGTAAGAGGGGAACAGCTGCTGTACATCGTCCTGGCGAGTGACAATGTGACAGAAGCCTGGGCGAGGCCCTCGGAGGGCAGCAGCTGGACAGGGACTACTGGGTTTGGCCTGGACAGCACTGATTTGTGGATGTGGATGGGGGCACGTTGTCCGTGATAAAAGTACAAGTGCCCCTCA

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