Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name RFC3P1
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr13). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:36169759-36170468  UCSC
Coordinates (T2T) chr3:36170652-36171361  UCSC
Coordinates (hg19) chr3:36211251-36211960  UCSC
Strand -
Parental Sequence XM_017020683.2
Parental seq. overlap 624 bp
Parental seq. overlap (%) 45%
Genomic Region Intergenic
Retrocopy Summary RFC3P1, located on chr3:36169759-36170468, is a retrocopy of the parental gene RFC3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RFC3
Full Name replication factor C subunit 3
Also known as RFC38
Coordinate chr13:33818075-33973946
Strand +
Gene summary The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Rhesus Macaca mulatta RFC3P1
Baboon Papio anubis RFC3P1
Golden snub-nosed monkey Rhinopithecus roxellana RFC3P1
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RFC3P1
CCCCAGGAACTCAAGCTTTCATGAGCCTCTGGGTAGACAAGTACCAGCCCTAATCCTTGGGATGGATGGAGTATCACAGGGAGCAGGCAGCCCAGCTATACAACCTGGTGCAGGGTGGTGAGTTTCCTCACCTTTAAGTGTATGGACCATCAGGTTCTGGAAAAAAGACAAGTGCTATGTGTGTTCTACATCAACTTTATGGTGTTGGAGTGGAAAAATTGAGAATTAAATACCAGACCATCAGGACTCCATCTAAAAAAATTGAAATTAGCACCATTGCAAGTAATTACCACCTTGAAGTTAATCCCAGTGATGCTGGAAATATTGATGAGGTAGTAATTCAGAAGATGTTGAAAACAGTGGCTCAGTCACAGCAACTTGAAACAAACTGTCAGATATTTTAAAATGGTATTATTGACAGAAGTTGACAAACTCATCAAAGATGCTCAACATGCCTTGTAAAGAACCATGGGAAAGTATATGTCCACCTACAGATTGATCTTGTGCCACAGTTCTACATCTAATGTGATACTACCTATTTGTAGTAGGTGCTTGGCAGTTGGTGTGCCTGCTCCCAGCATTGGAGATATTTACCATGTGTTATTTACTGTGTACAACAAGGAAGATCTGAATCTTCCTTCACAACTGACTCATAGACTTGCAGAAAAGTCCTGCAGAAACCTCACAAAAGCCCTGCTTATGTGt
>XM_017020683.2
GTCACGAGATTTGGAGCTCGCGGGAAAACTTGTCTCTGCGTTGTGGGGAGGACGCGCGCTCGCGCGGGATTTTCAAGCGTAGGCCCCCGGGAACTCGAGCTGCCATGAGCCTCTGGGTGGACAAGTATCGGCCCTGCTCCTTGGGACGGCTGGACTATCACAAGGAGCAGGCGGCCCAGCTGCGGAACCTGGTGCAGTGTGGTGACTTTCCTCATCTGTTAGTGTACGGACCATCAGGTGCTGGAAAAAAGACAAGAATTATGTGTATTCTACGTGAACTTTATGGTGTTGGAGTGGAAAAATTGAGAATTGAACATCAGACCATCACAACTCCATCTAAAAAAAAAATTGAAATTAGCACCATTGCAAGTAACTACCACCTTGAAGTTAATCCTAGTGATGCTGGAAATAGTGACCGAGTAGTCATTCAGGAGATGTTGAAAACAGTGGCACAATCACAACAACTTGAAACAAACTCTCAAAGGGATTTTAAAGTGGTATTATTGACAGAAGTTGACAAACTCACCAAAGATGCTCAGCATGCCTTGCGAAGAACCATGGAAAAATATATGTCTACCTGCAGATTGATCTTGTGCTGCAATTCTACATCTAAAGTGATCCCACCTATTCGTAGTAGGTGCTTGGCGGTTCGTGTGCCTGCTCCCAGCATTGAAGATATTTGCCACGTGTTATCTACTGTGTGTAAGAAGGAAGGTCTGAATCTTCCTTCACAACTGGCTCATAGACTTGCAGAGAAGTCTTGTAGAAATCTCAGAAAAGCCCTGCTTATGTGTGAAGCCTGCAGAGTGCAACAATATCCTTTTACTGCAGATCAAGAAATCCCTGAGACAGATTGGGAGGTGTATCTGAGGGAGACTGCAAATGCTATTGTCAGTCAGCAAACTCCACAAAGGCATGTAAGGAGGAATCAAGAAGCTGTGACATATTCTGAGGACCTCCAAAGAACAACTTGCTACTGACTGGACTTCTCTCATCTTTTAGCATGTGAAGTtttgcaaatataatccactttgctctgaatgtcctgacacctgcttcagagctcaagattcagactccagcctgaatgttatttcctgagaaaatccctccctgacccactgtgctggttaggtccacctgctaatcacatccacaaaaccctctgcttctccttcaaaacactcatctcctctgtaatgatcagatgaactcatgtctttctcagaggacaataaatttgatgaatggggaccatggaagtttatttccatctgtatccctacatctaactcatCTGCTGGTACCTATTTGTCATGTATTTAATAAGTACAACTACCTATGCCACCCTGCAATAAAATGATATTGTTACTTTCTCTTCTTTA

Publications

PMID - Link Title