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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DDTP1
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr22). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:38515307-38515668  UCSC
Coordinates (T2T) chr3:38521351-38521712  UCSC
Coordinates (hg19) chr3:38556798-38557159  UCSC
Strand -
Parental Sequence NM_001355.4_2
Parental seq. overlap 304 bp
Parental seq. overlap (%) 45.6%
Genomic Region Intragenic (EXOG)
Retrocopy Summary DDTP1, located on chr3:38515307-38515668, is a retrocopy of the parental gene DDT. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DDT
Full Name D-dopachrome tautomerase
Also known as D-DT|DDCT|MIF-2|MIF2
Coordinate chr22:23971370-23979828
Strand -
Gene summary D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. The DDT gene is related to the migration inhibitory factor (MIF) in terms of sequence, enzyme activity, and gene structure. DDT and MIF are closely linked on chromosome 22. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DDTP1
Bonobo Pan paniscus LOC100995427P1
Gorilla Gorilla gorilla LOC101147498P1
Gibbon Nomascus leucogenys DDTP1
Green monkey Chlorocebus sabaeus DDTP2
Crab-eating macaque Macaca fascicularis DDTP1
Rhesus Macaca mulatta DDTP1
Baboon Papio anubis LOC101016817P1
Golden snub-nosed monkey Rhinopithecus roxellana LOC104667410P2
Marmoset Callithrix jacchus LOC118142783P1
Orangutan Pongo abelii Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DDTP1
CGGGCCTGACCATGGTGCTGAGTAGGTCCACTGAGCCCTGGGCGCAGCTGTTCATCTCCTCCACCAGCATGATGGACACCACTGAGGAGAACCGCAGCCACAGCACCCACTTCTTCGAGTTCCTCACCGAGGAGCTGGCCCTGGGCCAGGACCAGATAATTTTCCACTTTTCCCCCCTGGAGCCCTGGCAGACTGGCAAGAAGGGGATGGTCATAACTTTTTAGTGACTGGCCTCGAGGGATCCAGGGCATCTGTGAGCTGGCTGCCCCTTCCAGAGAGTCCTCCTGGCAGAGCACCTGGTGTTACCAGCTTTGGGTAATTCCTCATGAGACATTCCCGTGACCTCATAATCCTCTTCTTCT
>NM_001355.4_2
GATCCCGGTGCCAGGGACCCTGCCCAGTTCCAGGCGTCGCCCTGACCCAGAAACGACTGGGCGCCGCCGTCCTGGAAAGGCCCCAGCGCACGGACATCTGAGGAGCTGTTTCCGTTCCTCTGCCCGCCATGCCGTTCCTGGAGCTGGACACGAATTTGCCCGCCAACCGAGTGCCCGCGGGGCTGGAGAAACGACTCTGCGCCGCCGCTGCCTCCATCCTGGGCAAACCTGCGGACCGCGTGAACGTGACGGTACGGCCGGGCCTGGCCATGGCGCTGAGCGGGTCCACCGAGCCCTGCGCGCAGCTGTCCATCTCCTCCATCGGCGTAGTGGGCACCGCCGAGGACAACCGCAGCCACAGCGCCCACTTCTTTGAGTTTCTCACCAAGGAGCTAGCCCTGGGCCAGGACCGGATACTTATCCGCTTTTTCCCCTTGGAGTCCTGGCAGATTGGCAAGATAGGGACGGTCATGACTTTTTTATGATTGGGCACGGAGGGATCCAGGGCATCTGTGAACTGGCTGCTTCTTCCAGAGAGATCTCTTGGCAGAGTGAGGGCCTGGAGATAACCAGCTTTGGATTATCCCGCATGCAACATTCCTGTGATCACATAATCCTCTTCTTCATCCTCATATGAAATAAATGAAGAGAGCTTCCTCATTCAAA

Publications

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