Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name UQCRC2P1
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:46310651-46311915  UCSC
Coordinates (T2T) chr3:46326535-46327799  UCSC
Coordinates (hg19) chr3:46352142-46353406  UCSC
Strand -
Parental Sequence NM_003366.4_2
Parental seq. overlap 1067 bp
Parental seq. overlap (%) 55.5%
Genomic Region Intergenic
Retrocopy Summary UQCRC2P1, located on chr3:46310651-46311915, is a retrocopy of the parental gene UQCRC2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name UQCRC2
Full Name ubiquinol-cytochrome c reductase core protein 2
Also known as MC3DN5|QCR2|UQCR2
Coordinate chr16:21953361-21983660
Strand +
Gene summary The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5. [provided by RefSeq, Jul 2015]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes UQCRC2P1
Bonobo Pan paniscus LOC100972888P1
Gorilla Gorilla gorilla LOC101130739P1
Orangutan Pongo abelii LOC100456655P1
Gibbon Nomascus leucogenys LOC100592631P2
Green monkey Chlorocebus sabaeus LOC103229564P2
Crab-eating macaque Macaca fascicularis LOC102135041P1
Rhesus Macaca mulatta UQCRC2P1
Baboon Papio anubis LOC101026315P1
Golden snub-nosed monkey Rhinopithecus roxellana LOC104682087P1
Marmoset Callithrix jacchus LOC100389097P6
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>UQCRC2P1
GAGACTTTATTCCCTCAAAGTTGCCCCCAAAGTTAAAGCCACAGCTACCCCCATAGGAGTGGCTCCACATCATCAGGACCTTGAGATCATCAAATTTCCAAATGGTTTTATGATTTCTCCTTTGGAAAACTATGCCCTGCATCAAGAATTGGTTTGTTCATTAAAGCAGGCAGTAGCTATGAGGACTCCAACAATTTAGTAACTTCTCATTTGCTGTGTCTTGCATCCAGTTTGACTACGAAAGGAGCTTCATTTTTCAAGATAGCCCATGACATTGAAGCAGCTGGTGGTAAATTAAGTGTAATTGCAACAAGAGAAAACATAGCTTACATCATGGAATGTCTGCAGAGTGATATTGATATTCTAATGGAGTTCCTGCTCAGTGTCGCCACAGCACCAGGATTTGGTCATTGGGAAGTAGATGCCTTCAGTCTCAGCTAAGGATAGACAGATCTGTGAATTTTCAGAATCCACAGGCACATGTCATTGAAAATTTGCATACTGAAGCTTATTGGGATGCCTTGGCTAATTCCTTGTATTGTCCTGGCTATAGGATTGGAAAAGTGACATGGGAAGAGTTACATTACTATGTTTAGAACCACTTCACAAGTGCAAGAATGGCTTGGTTGGACTTGGTGTGAGTCACCCTGTTCTAAAGCAAGTTGCTGAATAGTTTCTCAACAGGAGGGGTGGGTTTCTTTTGTCTGGTACAAAAGCCAAATACTCTGGAGGTGAAATTCAGGAACAAAATGGAGACAGTCTTGTCCATGCTTGCTCTTGTAGCAGAAAGTGCTGCCACAAGAAGGGCACAGCAAATGCATTTAGTGTTTTTCAGCATATCAAGAGGGACACCATATGTCAAGGGGCACAGTGATGCCACCAGCTATCTATAGCAGGCTATTGCCAAGGCAATTCACCAGCCACTTGCTATTTCTGTTTTTAATGCTAGTTACTCCAATTTTGGACTCTTCAGGATGTACATTGTCTTCCAGGCTGCAGCTGCTGGAGATGTTATCAAGGCTACCTATAACCAAGTGGAAATAATTGCTCAAGAAAAGCTTTTCAATGTCCAGGCTGCCAAGAACAAACTGAAAGCTGGATACCAAATATAAGTGAAGTCTTCCGAGGGTTTCATAGAAGAAGTCAGGCCCCAGGCTGTAGTTACTGGTTCTTACAAGCCAATATCACCAGTCCTTCAGTAGATTAGTTGGTTGGCTAGTGCTGTCATCATCAATTCTGCAAAGAAGTTTGCTTCTGGCTAGAAA
>NM_003366.4_2
CTCCGCCACCATCTTGCTTTCCTTTAATCCGGCAGTGACCGTGTGTCAGAACAATCTTGAATCATGAAGCTACTAACCAGAGCCGGCTCTTTCTCGAGATTTTATTCCCTCAAAGTTGCCCCCAAAGTTAAAGCCACAGCTGCGCCTGCAGGAGCACCGCCACAACCTCAGGACCTTGAGTTTACCAAGTTACCAAATGGCTTGGTGATTGCTTCTTTGGAAAACTATTCTCCTGTATCAAGAATTGGTTTGTTCATTAAAGCAGGCAGTAGATATGAGGACTTCAGCAATTTAGGAACCACCCATTTGCTGCGTCTTACATCCAGTCTGACGACAAAAGGAGCTTCATCTTTCAAGATAACCCGTGGAATTGAAGCAGTTGGTGGCAAATTAAGTGTGACCGCAACAAGGGAAAACATGGCTTATACTGTGGAATGCCTGCGGGGTGATGTTGATATTCTAATGGAGTTCCTGCTCAATGTCACCACAGCACCAGAATTTCGTCGTTGGGAAGTAGCTGACCTTCAGCCTCAGCTAAAGATTGACAAAGCTGTGGCCTTTCAGAATCCGCAGACTCATGTCATTGAAAATTTGCATGCAGCAGCTTACCGGAATGCCTTGGCTAATCCCTTGTATTGTCCTGACTATAGGATTGGAAAAGTGACATCAGAGGAGTTACATTACTTCGTTCAGAACCATTTCACAAGTGCAAGAATGGCTTTGATTGGACTTGGTGTGAGTCATCCTGTTCTAAAGCAAGTTGCTGAACAGTTTCTCAACATGAGGGGTGGGCTTGGTTTATCTGGTGCAAAGGCCAACTACCGTGGAGGTGAAATCCGAGAACAGAATGGAGACAGTCTTGTCCATGCTGCTTTTGTAGCAGAAAGTGCTGTCGCGGGAAGTGCAGAGGCAAATGCATTTAGTGTTCTTCAGCATGTCCTCGGTGCTGGGCCACATGTCAAGAGGGGCAGCAACACCACCAGCCATCTGCACCAGGCTGTTGCCAAGGCAACTCAGCAGCCATTTGATGTTTCTGCATTTAATGCCAGTTACTCAGATTCTGGACTCTTTGGGATTTATACTATCTCCCAGGCCACAGCTGCTGGAGATGTTATCAAGGCTGCCTATAATCAAGTAAAAACAATAGCTCAAGGAAACCTTTCCAACACAGATGTCCAAGCTGCCAAGAACAAGCTGAAAGCTGGATACCTAATGTCAGTGGAGTCTTCTGAGTGTTTCCTGGAAGAAGTCGGGTCCCAGGCTCTAGTTGCTGGTTCTTACATGCCACCATCCACAGTCCTTCAGCAGATTGATTCAGTGGCTAATGCTGATATCATAAATGCGGCAAAGAAGTTTGTTTCTGGCCAGAAGTCAATGGCAGCAAGTGGAAATTTGGGACATACACCTTTTGTTGATGAGTTGTAATACTGATGCACACATTACAGGAGAGAGCTGAACGTTCTCTCAGCCCAGAGCAGCAAACACATGAAAGTCAGAAGTCTCTAATATATCATTTGTCTTTTTTCCAGTGAGGTAAAATAAGGCATAAATGCAGGTAATTATTCCCAGCTGACCTAAAGTCAATAAAACATTCTGTTTAAGTGTTTTTCTTACGTTTTTCTCAATGAGTTAATCAACAAGTATTTATTATGTGCTGATATCTTTGTTTTAGATGCTTTAAAGGAGACAGGAATATAATTATTGAGTATAGAAGCATCAGAAACTATTAAAATTAAGGCTAAGTGGCTATCGGGGTAAATAGTGCCAGATTACTATTGGTGGCGTTTAAGATGAAAGCAAGTTCAAAATTTGTCATTTTGGGTGTCAACAGCTAAATGGTCTGGTTTTTACCCCTGTTTTGCCTTTTTTGCAATAAAATTATTTCCAAAAAAcatacatttcctatcaatcata

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