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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name BOLA2P2
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:47499791-47500141  UCSC
Coordinates (T2T) chr3:47518858-47519208  UCSC
Coordinates (hg19) chr3:47541281-47541631  UCSC
Strand +
Parental Sequence NM_001031827.2
Parental seq. overlap 301 bp
Parental seq. overlap (%) 29.6%
Genomic Region Intergenic
Retrocopy Summary BOLA2P2, located on chr3:47499791-47500141, is a retrocopy of the parental gene BOLA2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name BOLA2
Full Name bolA family member 2
Also known as BOLA2A|BOLA2B|My016
Coordinate chr16:29453588-29454964
Strand -
Gene summary This gene is located within a region of a segmental duplication on chromosome 16 and is identical to BOLA2B (bolA family member 2B). The product of this gene belongs to a family of proteins that are widely conserved and may be involved in iron maturation. Related pseudogenes are found multiple different chromosomes. Alternative splicing results in multiple transcript variants. Transcripts initiating at this locus may extend into downstream SMG1 pseudogene 6 (SMG1P6) and encode fusion proteins with a C-terminus related to SMG1 phosphatidylinositol 3-kinase-related kinase. A readthrough locus is represented with GeneID:107282092. [provided by RefSeq, Feb 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes BOLA2BP1
Bonobo Pan paniscus BOLA2BP1
Gorilla Gorilla gorilla BOLA2BP1
Orangutan Pongo abelii BOLA2BP1
Gibbon Nomascus leucogenys BOLA2BP1
Crab-eating macaque Macaca fascicularis BOLA2BP1
Rhesus Macaca mulatta BOLA2BP1
Baboon Papio anubis BOLA2BP1
Golden snub-nosed monkey Rhinopithecus roxellana BOLA2BP1
Marmoset Callithrix jacchus BOLA2BP1
Green monkey Chlorocebus sabaeus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>BOLA2P2
TTGGGGTTCTGTCCCTGCTGGGCTGTGGCCCCAGCTGGACTGCTGCCACAGAACTCAGCACCAAATAACTCCAGGAGAAGCTGCAGTGGGACCCGGAGGCGAAGCATATGGAGGTGGAGGACGTGACCCTCAACCGTCGTGCCTGCAGCTTCCGAGTCCTGGTGGTGTCGGCCAAGTTTGAGGGGAAGCTGCTGCTTCAGACACACTGGCGGGTAAATATGTGGCTAGCTGGAGGCTCTCGCACATCCATGCTTTTGAGCAGAAAACCCTCATCCCAGAGCAGTGGGCTTGTGAACGGCAGAAAGGAGGGACTGGCATCTGCACAGCCATTAAATTATAAATCAGGACCAG
>NM_001031827.2
CTTCCTCCCGGCACAGAAGGCCTCCCCCTCTCACCAGGGCCCTCGCCCGCTGGTCCGCCAGGCCCCGCCTTTTTTGCGGCCCCCATTGTGCTGCTGGACCCGACGAGCAGTGTTGACAGTGAACCCCACGTAGACGCGGCCCCGGTACCGGGGGTTCAGGCAGTAGAGCAGGTAGACGCCGAAAAAGCGCCCTGGCCTCGCCGCGACCCCCGCGGGACCCATCGGGCCTTGGGGTTCGGGAACCACAGCAGGGGGTTGATTGCCGTGACCTAGGGTCCAGGGGAGGGCTGGATCGCTAGGGCTGCAGGGTGCTTGCTTCGGAACAAGCTCTCGGGGACTATCCGGAGGCAGCCTGCAGGAAGCCGTAGCGCCGGTACGTGCCCCTCTCCTGTCTGGAGGCGGGTGTAGAAGTCCGACCGCGGAAGCCAGACTGCTGTCCAGTCGGCGAGCGCGTACCATTCAGCATCGGCTCCGCCCGAGTCCCACCTTCCTCAGGCTCTGATTGGCTGACACATGGCAAGCGCGAAAAGCCTGGACCGCTGGAAAGCCCGGCTGCTTGAGGGCGGAAGTACTGCGTTGACGTACGCCTTAGTAAGGGCGGAAGTGAGTTTTCCAGCGGAAGTGGCTCCTGTAAGGCAGCAAGGTAGCGTGGCCGGCGCCCGAGCTGGGGTTGTGTCCCTGCTGGGCTGCCGTTCCAGCTGGACTGCCGCCATGGAACTCAGCGCCGAATACCTCCGCGAGAAGCTGCAGCGGGACCTGGAGGCGGAGCATGTGGAGGTGGAGGACACGACCCTCAACCGTTGCTCCTGTAGCTTCCGAGTCCTGGTGGTGTCGGCCAAGTTCGAGGGGAAACCGCTGCTTCAGAGACACAGGCTGGTGAACGCGTGCCTAGCAGAAGAGCTCCCGCACATCCATGCCTTTGAACAGAAAACCCTGACCCCAGACCAGTGGGCACGTGAGCGACAGAAATGAGGGACTGGGATCTGCACAGCCATTAAATTATAAATCTGGACCAGC

Publications

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