Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RNPC3P1
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:70124854-70126615  UCSC
Coordinates (T2T) chr3:70161766-70163527  UCSC
Coordinates (hg19) chr3:70174005-70175766  UCSC
Strand -
Parental Sequence NM_017619.4
Parental seq. overlap 1644 bp
Parental seq. overlap (%) 76.5%
Genomic Region Intergenic
Retrocopy Summary RNPC3P1, located on chr3:70124854-70126615, is a retrocopy of the parental gene RNPC3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RNPC3
Full Name RNA binding region (RNP1, RRM) containing 3
Also known as CPHD7|IGHD5|RBM40|RNP|SNRNP65
Coordinate chr1:103525699-103555239
Strand +
Gene summary Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RNPC3P1
Bonobo Pan paniscus RNPC3P1
Gorilla Gorilla gorilla RNPC3P1
Orangutan Pongo abelii RNPC3P1
Gibbon Nomascus leucogenys RNPC3P1
Green monkey Chlorocebus sabaeus RNPC3P1
Crab-eating macaque Macaca fascicularis RNPC3P1
Rhesus Macaca mulatta RNPC3P1
Baboon Papio anubis RNPC3P1
Golden snub-nosed monkey Rhinopithecus roxellana RNPC3P1
Marmoset Callithrix jacchus RNPC3P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RNPC3P1
GAAAATGCCAGCTCTCTATCAGCCATTTGCAATATCAAGGGGATGCACAAGCTCCTCCCCACTTTCCCTGCCTCGGCCGACCGAACTCTTCTGGTGAGGCACCTGCCAGCTGAGCTGACCGCTGAGGAGAAAGAGGACTTGCTGAAGTACTTCAAGGCACGGTTGGTGCATGACCTGTCAGATAAGGGGCAGCTGAAACATACAGCTTTTGCCACATTCCCTAAAAAGCAGCTATAAAGGCATTGACAAGACTCCATCAGCTGAAACTTTTAGGTCATACTTTAGTCTTTGAATTTGCAAAAGAGCAAGATCAAGTTCACTCCCCATGTCCCACTCCAGTCTCTGAAAAAAAAAAAAAAAGGTCTGATGACCCTGTTGAAGACGATAAAGAAAAGAAAGAATTGGTTATTTAACAGTAGAAAATGTAATTACACCAAACCATGGGCTGACTTTTCTTAATTCATGCCTCAAGTATATGTACCCACCACCTTCCAGCACAATCCTAACAAACAGAGTAAATGCTTTGGCAAGCGTGCCTAAGTTCTATGTACAGGTCCTTCATCTTATGAATAAAATGAATTTGCCCACAGCTTTTAGATCAATTACTGCGCAGCCTCCCATCTATGAAGACCATATGCCATTGCATCCACCTCTTCCACCCACATCTCCTCAGCCACCTGAGGAACCTCCTTGGCCAGAAGACGATGAGGAATTATCTAGTGAAGAATTAGAAGATGACAGCAGTGATGATGAGGACCAACAGAAAATGAACAAACTAATGGAACTAGCAAATCTTCAGCCCCAAAGACCCAAAACAATAAGGCAGCGCCATGTGAGAAAAAAGAGAAAAATAAAGGATATGTTGAACATACTTTCGTGTCCTTCACAAAACAGTTTACATCTAGTGCTGTTACCTTCGGATGTATTTGACCAACCACAACCTGTAGGTAATAAAAGAATTGAATTCCATATATCTACCGACATGCCAGCTGCATTTAAGAAAGATTTAGAGAAGAAACAAAATTGTGAGAAAAAAATAATGATCTACCTGTTACTGAAGCTGATGCATCCAGTATAGGATTTGGAAAAATCTTTCCCAAACCTAATTTGAACATCACAGAAGAGATTAAAAAAGACTCTGATGAAATGCCATCGGAATGTATTTCTAGAAGGGAATTGGAAAAGGACAGAATTTCTAGAGAAGAAATGGAAACACTTTCAGTTTTCAGAAGTTATGAACCTGGTGAACCAAACTGTAGAATTTATGTAAAGAATTTAGCTAAACATGTTCAAGAAAAGGACCTTAAATATATTTTTGGAAGATATGTTGACTTTTCATCAGAAACACAGTAGATCATGTTTGATATACGTTTGATGAAAGAAGGTCGTATGAAAGGACAAGCTTCCATTGGACTTCCTAATGAAAAAGCAGCAGCAAAAGCCTTAAAGGAAGCTAATGGATATGTGCTTTTTGGAAAACCCATGGTGGTTCAATTTGCTCGATCTGCTAGACAAAAACCAGATCCTAAGGAAGGAAAAAGAAAGTGTTAAAAATTAATAAAGGTTTCTTTTGAATCCTGTATCTTTCAAGGGCTTTCCAACTTGGACAGGAAGAAATTGACCACCTGGACTATGGAACTGTGCATAACAGCTTTGAAAGTATATTTAAAAATTAAATACATATGCCTTTAAATCAGTGTATTGGAACTATATTATATGTATTTTAATGACCTTCCTCAAATATAATAAATTAttttctttt
>NM_017619.4
GCAGTCGTGAGTCCTCTTGTCCTTGAGCGTCAACCTTCTTTCCCTGAAGTGGCTGGGGTTCCTGTTTCCTTCTTTGATTGACAACTTGTGTTAACCCTCGCACATCTCTGGGCCAATTTTTGCTTGTAAGTCTTTCCGGAGACCCCTGGAATTTAAATCATTAGCACCGCGCCCTTCCCCGAAGAGTCTTCGAAGGGTTGCCGCTTTTCGGTGGCGCAGTTCTCGCGAGAAGGTGACTTTCTTTCTCGGTATTTCCTGGTTTCCAGAATCCTTAGCGCGAGGCGGAAAAAATATTTCTCCCAGCTTGTGTTGATGCCGCGATTTTGACTGAGACTTCTTCCCACGATTTCTGTTTTTGCTTCTCCAAGGAAAATGGCAGCTCCCGAGCAGCCGCTTGCGATATCAAGGGGATGCACGAGCTCCTCCTCGCTTTCCCCGCCTCGGGGCGACCGAACCCTTCTGGTCAGGCACCTGCCGGCTGAGCTTACTGCTGAGGAGAAAGAGGACTTGCTGAAGTACTTCGGGGCTCAGTCTGTGCGGGTCCTGTCAGATAAGGGGCGACTGAAACATACAGCTTTTGCCACATTCCCTAATGAAAAAGCAGCTATAAAGGCATTGACAAGACTCCATCAACTGAAACTTTTAGGTCATACTTTAGTCGTTGAATTTGCAAAAGAGCAAGATCGAGTTCACTCCCCATGTCCCACTTCAGGCTCTGAAAAAAAAAAAAGGTCTGATGACCCTGTCGAAGATGATAAAGAAAAAAAAGAACTTGGTTATTTAACAGTAGAAAATGGAATTGCACCAAACCATGGGCTGACTTTTCCTTTAAATTCATGCCTCAAGTATATGTACCCACCACCTTCCAGCACAATCCTAGCAAACATTGTAAATGCCTTGGCAAGCGTGCCTAAGTTCTATGTACAGGTCCTTCATCTTATGAATAAAATGAATTTGCCCACACCTTTTGGACCAATTACTGCGCGACCTCCCATGTATGAAGACTATATGCCATTGCATGCACCTCTTCCACCCACATCTCCTCAGCCACCTGAGGAACCTCCTTTGCCAGACGAGGATGAGGAATTATCTAGTGAAGAATCAGAATATGAAAGCACTGATGATGAGGACCGACAGAGAATGAACAAATTAATGGAACTAGCAAATCTTCAGCCCAAAAGACCTAAAACAATAAAGCAGCGCCATGTGAGAAAAAAGAGAAAAATAAAGGATATGTTGAATACACCTTTGTGTCCTTCACACAGCAGTTTACATCCAGTGCTGTTACCTTCAGATGTATTTGACCAACCACAACCTGTAGGTAACAAAAGAATTGAATTCCATATATCTACCGACATGCCAGCTGCATTTAAGAAAGATTTAGAAAAGGAACAAAATTGTGAGGAAAAAAATCATGATTTACCTGCTACTGAAGTTGATGCATCCAATATAGGATTTGGAAAAATCTTCCCCAAACCTAATTTGGACATCACAGAGGAGATTAAAGAAGACTCTGATGAAATGCCTTCAGAATGTATTTCTAGAAGGGAATTGGAAAAGGGCAGAATTTCTAGAGAAGAAATGGAAACACTTTCAGTTTTCAGAAGTTATGAACCGGGTGAACCAAACTGTAGAATTTATGTAAAGAATTTAGCTAAACATGTTCAAGAAAAGGACCTTAAATATATTTTTGGAAGATATGTTGACTTTTCATCAGAAACACAGCGGATCATGTTTGATATACGTTTGATGAAAGAAGGTCGTATGAAAGGACAAGCTTTCATTGGACTTCCTAATGAAAAAGCAGCAGCAAAAGCCTTAAAGGAAGCTAATGGATATGTGCTTTTTGGAAAACCCATGGTGGTTCAGTTTGCTCGATCTGCTAGACCAAAACAAGATCCTAAGGAAGGAAAAAGAAAGTGTTAAAAATTAATAAAGGTTTTTTTGAATCCCGTGTCCTTCAAGTGCTTTCTAACTTTGAGAGGAAGAAATTGACCACCTGGACTATGGAACTGTGCGTAACAGCTTTGAAAGTGTATTTAAAAATTAAATCTATATGCCTTTAAATCAGTGAATTGGAAACATATTACATGTATTTTAATGATTTTCCTCAAATATAATAAATTGTTTCCTTTCCAATAAAA

Publications

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