Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name UQCRHP4
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:70140143-70140679  UCSC
Coordinates (T2T) chr3:70177059-70177595  UCSC
Coordinates (hg19) chr3:70189294-70189830  UCSC
Strand +
Parental Sequence NM_006004.4
Parental seq. overlap 430 bp
Parental seq. overlap (%) 79%
Genomic Region Intergenic
Retrocopy Summary UQCRHP4, located on chr3:70140143-70140679, is a retrocopy of the parental gene UQCRH. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name UQCRH
Full Name ubiquinol-cytochrome c reductase hinge protein
Also known as QCR6|UQCR8
Coordinate chr1:46303698-46316776
Strand +
Gene summary Predicted to enable ubiquinol-cytochrome-c reductase activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes LOC742376P3
Bonobo Pan paniscus LOC100984974P3
Gorilla Gorilla gorilla LOC101132095P3
Orangutan Pongo abelii LOC100450040P2
Gibbon Nomascus leucogenys LOC100589568P4
Green monkey Chlorocebus sabaeus LOC103224893P5
Crab-eating macaque Macaca fascicularis LOC102136267P1
Rhesus Macaca mulatta UQCRHP1
Baboon Papio anubis LOC101006001P1
Golden snub-nosed monkey Rhinopithecus roxellana LOC104662117P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>UQCRHP4
CCTTCTTGATTCTGAGGTGGATTAGGTGCCGCTGTTGCTGCTTGAGTGTGTTGAATTCAGAACCATAGCCAGACATGGGACTGGAAGATGAGTGAAAGATACTGACCAGGTCCGAAGATCTCATaATTACTGGATCCCCCAACAACAGAAAGAGAGCAATGCAAGCAGCTGGAGAAATGTGTAAAGGCCAGGAGTGGCTAGAGCTCTGTGATGAGTGTATATCCTTCCAGTCACAAAGAAGAGAATGCCATGGAGGAGCTTTGGACTTTTTGCATGCAAGGGACCACTGAGTGACCCACAAACTCTTTAACAGCTTGAAATAAATGTGCAGACATATTTACTTCAGCCTTCATCACCTTGGCATAAGGATCTTTCCTTATGGTTTTGAATATGCCATTTGCTTCTAATTTGTGTAACTGTAAGTTTATATTAACCTCGTGGATTTTGGCTTCGACAAGTAGCTTCTAGGTAATTAGCAGTGATTCTATCTTAATGAAGTTCTGTGATCTACAAA
>NM_006004.4
CTTCTTGATCCTGAACTGGGTTAGGTGCCGCTGTTGCTGCTCGTGTTGAATCTAGAACCGTAGCCAGACATGGGACTGGAGGACGAGCAAAAGATGCTTACCGAATCCGGAGATCCTGAGGAGgaggaagaggaagaggaggaATTAGTGGATCCCCTAACAACAGTGAGAGAGCAATGCGAGCAGTTGGAGAAATGTGTAAAGGCCCGGGAGCGGCTAGAGCTCTGTGATGAGCGTGTATCCTCTCGATCACATACAGAAGAGGATTGCACGGAGGAGCTCTTTGACTTCTTGCATGCGAGGGACCATTGCGTGGCCCACAAACTCTTTAACAACTTGAAATAAATGTGTGGACTTAATTCACCCCAGTCTTCATCATCTGGGCATCAGAATATTTCCTTATGGTTTTGGATGTACCATTTGTTTCTTATTTGTGTAACTGTAAGTTCACATGAACCTCATGGGTTTGGCTTAGGCTGGTAGCTTCTATGTAATTCGCAATGATTCCATCTAAATAAAAGTTCTATGATCTGCAAA

Publications

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