Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NIPA2P2
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:75084438-75085214  UCSC
Coordinates (T2T) chr3:75126261-75127037  UCSC
Coordinates (hg19) chr3:75133589-75134365  UCSC
Strand +
Parental Sequence NM_001008894.3
Parental seq. overlap 659 bp
Parental seq. overlap (%) 22.6%
Genomic Region Intergenic
Retrocopy Summary NIPA2P2, located on chr3:75084438-75085214, is a retrocopy of the parental gene NIPA2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NIPA2
Full Name NIPA magnesium transporter 2
Also known as SLC57A2
Coordinate chr15:22838641-22868384
Strand +
Gene summary This gene encodes a possible magnesium transporter. This gene is located adjacent to the imprinted domain in the Prader-Willi syndrome deletion region of chromosome 15. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 7 and 21.[provided by RefSeq, May 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NIPA2P1
Bonobo Pan paniscus NIPA2P1
Gorilla Gorilla gorilla NIPA2P1
Orangutan Pongo abelii NIPA2P1
Gibbon Nomascus leucogenys NIPA2P2
Green monkey Chlorocebus sabaeus NIPA2P2
Crab-eating macaque Macaca fascicularis NIPA2P1
Rhesus Macaca mulatta NIPA2P1
Baboon Papio anubis NIPA2P1
Golden snub-nosed monkey Rhinopithecus roxellana NIPA2P1
Marmoset Callithrix jacchus NIPA2P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NIPA2P2
AAAGTGCTACTCTTTCTTCATACTTTTTAAATGAATGACTTAATCTCATGGGAATATTGGGTAGTTGCTAAGTATTCTAGGATCTACAGTTATGGTCAGTCTGCCATGCTTTAAAAGAAGAGGGGTTAGAGAACTTATAGGAAATGTTTCACAAGCTAGGTGATTCAGGTTTTGTGGTGTTTGCAACACTCGTGGTCATTGTGTCCCTGATTATTAATCTCTATAGTGGGACTTTGCCATGGACAGATAAATGTTCTTGTGTATATAACCATTGACTCTGTAATTGGAGCATTTTCAGTCTTCTGTGTGAAGGGCTTAGGCATTGCTATTAAAGAGTTGTCGCCTGGACTTTGACGTGCCCTGACATGATTTCGCTGCTGAGCTTTGTTGTCTGTGTGAGCCCACAGATTAATTACCTAAATAAGGCCCTGAATATATTCAACAATTTTATAGTGACTCCAATACATGAAGTATTTTTTACAACATTAGTTTTAACTTGTTCAGCTATTCTTTTTAAGCCATGTCAAGGTATGTCTGTTGATAATGTCATTGATACTTTGAGTGGCTTTTTATAATCATTGTGGGGATATTCTTGTTGCAAGCCTTTAGAGATGTCAGCTTTAATTTAGCAAGTCTGCCTCTGCCTATCCTAAAAGGCGAAAAAGAAAGGAATAGCAACCTCTCTAATATCTAAAGTTTTTAATAATAATGAAGAAGGCTTAACCTGTGGAATTGAACAACATACTGGTGAAAATAACTCCTGAATACATGGAAATC
>NM_001008894.3
CGGCGCCGGCCCTAGGTCCCGGCAGCGGTGGTGACGGCGGTGCCGGAGGTTGTCCTTGGCAGGTTTTCCTCGGCGCTTCTCCATGGAGGAGGCGGTGCGAACGGCTTCAGCCCCGAATGCTCGCATCTCCCACTGGACGGCGACGAAGGCGGTGGCCGTGCGAGCGCAGGACTGGGCGGCCTGTGTGGGGGTGTGAGCCGCGGTGCCCAAGGCTGCGCCGGCGAGGGGAAGCCGCGCGGCCGGCCGGCCGACTAGGGTTTGAAGACTGCTTCATTCTGCCTCTAGTACCAGCGGTTTCTCTGTTCTGTGATCAATGTGATTCACAGGAACTCCTTAAGTAACAAACGAAATGAGCCAGGGGCGTGGAAAATATGACTTCTATATTGGTCTGGGATTGGCTATGAGCTCCAGCATTTTCATTGGAGGAAGTTTCATTTTGAAAAAAAAGGGCCTCCTTCGACTTGCCAGGAAAGGCTCTATGAGAGCAGTGGGAGCTGGTGAGGTGGCCAACTTCGCTGCGTATGCGTTTGCACCAGCCACTCTAGTGACTCCACTAGGAGCTCTCAGCGTGCTAGTAAGTGCCATTCTTTCTTCATACTTTCTCAATGAAAGACTTAATCTTCATGGGAAAATTGGGTGTTTGCTAAGTATTCTAGGATCTACAGTTATGGTCATTCATGCTCCAAAGGAAGAGGAGATTGAGACTTTAAATGAAATGTCTCACAAGCTAGGTGATCCAGGTTTTGTGGTCTTTGCAACCCTTGTGGTCATTGTGGCCTTGATATTAATCTTCGTGGTGGGTCCTCGCCATGGACAGACAAACATTCTTGTGTACATAACAATCTGCTCTGTAATCGGCGCGTTTTCAGTCTCCTGTGTGAAGGGCCTGGGCATTGCTATCAAGGAGCTGTTTGCAGGGAAGCCTGTGCTGCGGCATCCCCTGGCTTGGATTCTGCTGCTGAGCCTCATCGTCTGTGTGAGCACACAGATTAATTACCTAAATAGGGCCCTGGATATATTCAACACTTCCATTGTGACTCCAATATATTATGTATTCTTTACAACATCAGTTTTAACTTGTTCAGCTATTCTTTTTAAGGAGTGGCAAGATATGCCTGTTGACGATGTCATTGGTACTTTGAGTGGCTTCTTTACAATCATTGTGGGGATATTCTTGTTGCATGCCTTTAAAGACGTCAGCTTTAGTCTAGCAAGTCTGCCTGTGTCTTTTCGAAAAGACGAGAAAGCAATGAATGGCAATCTCTCTAATATGTATGAAGTTCTTAATAATAATGAAGAAAGCTTAACCTGTGGAATCGAACAACACACTGGTGAAAATGTCTCCCGAAGAAATGGAAATCTGACAGCTTTTTAAGAAAGGTGTAATTAAAGGTTAATCTGTGATTGTTATGAAGTGAATTTGAATATCATCAGAATGTGTCTGAAAAAACATTGTCCTCAAATAATGTTCTTTAAAGGCAATCTTTTTAAAGATTTCACTAATTTGGACCAAGAAATTACTTTTCTTGTATTTAAACAAACAATGGTAGCTCACTAAAATGACCTCAGCACATGACGATTTCTATTAACATTTTATTGTTGTAGAAGTATTTTACATTTTCATCCCTTCTCCAAAAGCCGAATGCACTAATGACAGTTTTAAGTCTATGAAAATGCTTTATTTTTTCATTGGTGATGAAAGTCTGAAATGTGCATTTGTCATCCCCACTCCATCAATCCCTGACCATGTAAGGCTTTTTTATTTTAAAAAAACAGAGTTATCCCAATACATTATCCTGTGATTTACCTTACCTACAAAAGTGGCTCCTGTTTGTTTGATGATGATTGGTTTTATTTTTGAAATATTTATTAAGGGAAAACTAAGTTACTGAATGAAGGAACCTCTTTCTTACAAAACAAAAAAAAGGGCAGAAATCACCCCAAGGAACGATTTCTCAGGTTGAGATGATCACCGTGAATCCGGCTTCCTCTGAGCATTCGATGGCCTTAGCACCTCATCAAGCCAGCACATCCTGCCTGCTGTTGCAGCCTGGCTGGGTTTATTCTTCAGTTACCCTAATCCCATGATGCCTGGAACCTTGATTACCGTTTTACATCAGCTCTTGTACTTTTCAGTATATTTTCATAATGAGTTATATTGTCATTTAGACTTTGAACAGCTCTGGGAAATAGAAGACTAGGGTTGTTTCTTAAATTTAGCTCATGTTATAATAAAAAGTTGAAATGAAGTTCTTATTCTAAAAGTCTGAATGCTTAGAACAAACTTAACATGTTTATAGAATATGGTCTCTTTGTACCAAGTACTTTGCTTAAGAGCTCCTTTGGGCCACTACATATTTTGGTTTCTAGAAAATGTTTGTTTATGAAGAAGTCGatggaaaactgcaaacatatgcagaaaaggtagaataataaaaaaggtctaatgaactccattcagctttgaacctatccactcataaccaTTGACTGGCCTTTAAAAAAAAGTATTGGCAGAATTAATTTCCACCTAGGTGATGGGAAGAAAGTGTTCGCCTGTTCCAGCCTGTGGCTCCTGCCTGGAGGTTACCCAGTGGTGCGCCAGCGCCAAGCCATCACTCCCCGAGGGCCTCCCCTGCCAATGGTGCTGGTATCCCATGCAGCTCACCACTGGCTGCGTGGAAACTCccttttttccaactttattattggccttctaaggagctgttttagatgttttttctaactgcctcctcccatgccattttaatactacagatgtactacgtatctgtttatatactgtacctacatctgtgctttgtacataaaaGAACCAGTTTTCTCCCCCTTGAGGACAGAGACTCATTTGAACATGCATAGGTTAATAAATAATAAATTCTTATTTAACA

Publications

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