Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name EIF2S3P2
Plot displaying the genomic locations of a retrocopy (in chr4) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr4:112797025-112798259  UCSC
Coordinates (T2T) chr4:116105381-116106615  UCSC
Coordinates (hg19) chr4:113718181-113719415  UCSC
Strand -
Parental Sequence NM_001415.4
Parental seq. overlap 1025 bp
Parental seq. overlap (%) 29.5%
Genomic Region Intragenic (ANK2)
Retrocopy Summary EIF2S3P2, located on chr4:112797025-112798259, is a retrocopy of the parental gene EIF2S3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name EIF2S3
Full Name eukaryotic translation initiation factor 2 subunit gamma
Also known as EIF2|EIF2G|EIF2gamma|MEHMO|MRXSBRK|eIF-2gA
Coordinate chrX:24054956-24078810
Strand +
Gene summary The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit. [provided by RefSeq, Jan 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes EIF2S3P2
Bonobo Pan paniscus EIF2S3P2
Gorilla Gorilla gorilla EIF2S3P2
Orangutan Pongo abelii EIF2S3P2
Gibbon Nomascus leucogenys EIF2S3P1
Green monkey Chlorocebus sabaeus EIF2S3P1
Crab-eating macaque Macaca fascicularis EIF2S3P7
Rhesus Macaca mulatta EIF2S3P7
Baboon Papio anubis EIF2S3P4
Golden snub-nosed monkey Rhinopithecus roxellana EIF2S3P2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>EIF2S3P2
TGTCAGGTTCAAAAATGAACTGTAAAGAAATATTACTATCAAGTTTGGACACATTAAATGCCAAGATTATAAACTCGATGACTCAAGTTTCCTCGGCCAGAATATTACAGATTCTGTGGAAGTAGTACACCTTGATGAGTTTCCTATAAATATTCCAGGGACCAAAAGAAACTTTGAACTAGTCAGACATGTTTCCTTGGTTGACTGTCCTGCCATGATATTTTGATGGCTACTTTGATGAACGGTATAGCAGTGATGGATGTGACCTTTCTGTTGATAGCCGGCAAAGAATCTTGTCCTCAACCTCAGACTCCTCTGAACACCTGGCTGCCATAGATATTATGAAGCTGAAACATACTTTCATTCTGTAAAATAAAATTAATTTGGTAAAAGAAAGTAAGGCTAAAGAACAGTATGAACAGATCCTTTCATTGTATTAATATAAAGTAGAGTAGCAGAAGAGCCTCCTATTATTTTCATTTCTGCTAAGCTGAAATACAATCTTGAAGTTGTCCGTGAGTATATAGCAAGGAAAATTTCAGTACCTCCAAGAGACTTTACTTCAGAACCCCAACTTATTGTTATTAGGTCGTTTGATGTTAACGAACCTGGCTGTGATATTGATGATATTACCAGGGAGAACAACTGGTGGCAGTATTTAAAAAGGTGTATTAAAGGTGGTCCAGGAGACAGGAGTCAGACTTGGTATTGTTCCCAAAAATAGTGAAGGAAAACTCATGTGTAAAACAATCATTTCCAAACTTGTATCACTTTTTGCAGAATACAATGATCCTCAGTACACTGCTCCAGGGAGTCTTACGGGAGTTGGAACAAAAATTTACCCAACATTCATAGAATGGCCGGGCAGGTGCTTGGTGCAGTTGGAGCTGTACCTAAGATCGTCACAGGACCAGAAATGTCCTATTTACTGCTTAGACAGCTCTAGGTGTATGTATAGAAGAAGGCAAAAAAACAGAAAAAGTACAAAAGCTGTCCATGAGCAAAGTTCTTATAGTAAACATACGATCTCTGTCTACAGGAAGAAGAGAGTGCAGTCAAAGATGATTTGGGTAAAATAGTTCTCACTAATCCTGTGTGCACAAAAGTAGGAGAAAAAAATTGCCCTTAGCCAAAGAGCTGAGAAACATTAGCATTTAATTCGTTGGGATCAGATAGAAGAGGAGTGGCCATGAAGCCAACAGTAGATGACAAGTGAAGAATTACAGTTAAATAAC
>NM_001415.4
CTCTTTTGGCAACATGGCGGGCGGAGAAGCTGGAGTGACTCTAGGGCAGCCGCATCTTTCGCGTCAGGATCTCACCACCTTGGATGTTACCAAGTTGACGCCACTTTCACACGAAGTTATCAGCAGACAAGCCACAATTAACATAGGTACAATTGGTCATGTAGCTCATGGGAAATCCACAGTCGTCAAAGCTATTTCTGGAGTTCATACTGTCAGGTTCAAAAATGAACTAGAAAGAAATATTACAATCAAGCTTGGATATGCTAATGCTAAGATTTATAAGCTTGATGACCCAAGTTGCCCTCGGCCAGAATGTTATAGATCTTGTGGGAGCAGTACACCTGACGAGTTTCCTACGGACATTCCAGGGACCAAAGGGAACTTCAAATTAGTCAGACATGTTTCCTTTGTTGACTGTCCTGGCCACGATATTTTGATGGCTACTATGCTGAACGGTGCAGCAGTGATGGATGCAGCTCTTCTGTTGATAGCTGGTAATGAATCTTGCCCTCAGCCTCAGACATCGGAACACCTGGCTGCTATAGAGATCATGAAACTGAAGCATATTTTGATTCTACAAAATAAAATTGATTTGGTAAAAGAAAGTCAGGCTAAAGAACAATACGAGCAGATCCTTGCATTTGTCCAAGGTACAGTAGCAGAGGGAGCTCCCATTATTCCAATTTCAGCTCAGCTGAAATACAATATTGAAGTTGTTTGTGAGTACATAGTAAAGAAAATTCCAGTACCCCCAAGAGACTTTACTTCAGAGCCCCGGCTTATTGTTATTAGATCTTTTGATGTCAACAAACCTGGCTGTGAAGTTGATGACCTTAAGGGAGGTGTAGCTGGTGGTAGTATCCTAAAAGGAGTATTAAAGGTGGGCCAGGAGATAGAAGTAAGACCTGGTATTGTTTCCAAAGATAGTGAAGGAAAACTCATGTGTAAACCAATCTTTTCCAAAATTGTATCACTTTTTGCGGAGCATAATGATCTGCAATATGCTGCTCCAGGCGGTCTTATTGGAGTTGGAACAAAAATTGACCCCACTTTGTGCCGGGCTGACAGAATGGTGGGGCAAGTACTTGGTGCAGTCGGAGCTTTACCTGAGATATTCACAGAATTGGAAATTTCCTATTTCCTGCTTAGACGGCTTCTAGGTGTACGCACTGAAGGAGACAAGAAAGCAGCAAAGGTTCAAAAGCTGTCTAAGAATGAAGTGCTCATGGTGAACATAGGATCCCTGTCAACAGGAGGGAGAGTTAGTGCTGTCAAGGCCGATTTGGGTAAAATTGTTTTGACCAATCCAGTGTGCACAGAGGTAGGAGAAAAAATTGCCCTTAGCCGAAGAGTTGAAAAACACTGGCGtttaattGGTTGGGGTCAGATAAGAAGAGGAGTGACAATCAAGCCAACAGTAGATGATGACTGAAGAATACCAGTTAAATAATACATTCGGATGGATTTGGAAGTTGGAATTCCTCTTAACAACCAAGGGGTTTATTTTCAAAGCAATATTGGGGAATTGATTTCACAGTTCGTTACCTTAGTAGGTAACGGTAAGGttattctctttttttttttttttttttttGGTTATGAAAACTTAGGGACTAAAATTAATATAAAAATTGGCATAATGTTGGATTGAATCTACATTTTGGCAGAAGTTAAACATTCCCACATAATGTCAAAATTATACATCATGCAGTTCTGTTtttttgtttgttttattttgttttgtttttgagtctggctctgtcacccaggctggagtgcagtggcgtgatctgcaacctctgccccccgggttcaagcgattctcctgcctcagcctcccgagtagctgagattacaggtgcgcgccaccacacttggctaatttttgtattattagtagagacggggtttcagcatgttggctaggccggtctctcctgacctcagggtgatcagcccacctcggcctcacaaagtgctgggattacaggcgtgagccaccttgcccagccCACATCATACAGTTTGAAATGAAACTTTGCCACAACCAGCCTTTGCTGTAGCACACACATATATCACTGAACCTGTTTGAAATAAAGTTTTTTTTCTTTTTCATGATTCGTCTTTGAGTACCTCCAGGCTGAAAGACTGTTGTACCAGTAAAAACTTAAAGGCACAAATTCTCCTTGAAGACCTTCTCCCTTTTATGTGGCCCCATATTTTATGTTGCTTTATCTTTGAAATTTTGCATGAAAAGGAAATGAATGGATTCGAATGAAATTGTCCTTTAGAGCATGATTACTTGTTCCCATGGACAAATATTTTTCTCCCCTTGCTCTTCCTGGCCTGAAACACGGGAAACCAGAGTCAAAAGTTATCTCCCTCTCCCTGTGATGCCTTGAGATTTTTTTCTGCGTTGTTTAATGCCTGAAATCCAAGTCTTCCTCCATGGGAAAATACTGTTATACCAAATAATTCTAGATGAGTAACAAAGATCTTTTTAGGCCTTCATTTTATGTTTTTTCTTAACTGTTATATTATGATTGTGACATAGATTATACTACTACTAATTTTTGGATGTTTCAAAAGGTCAAGAAGTAAAAGATGTTAGAAAGCAATGAGTGAGTCCTTTTGATTTTTAACTTATTCCCCATGTCCCTATACTTCGTGTGCttttcctttttttttttgagacggaggctcactccgtcacctaggctagagtacagtggcacgatcttggctcgctgcaacctctgcctccctgattcaagtgattctcgtgcttcagcctcccatgtagctgatattacaggcacttgccaccatacccggctaatttttgtatttttagtagagatggggtttcaccatgttgcccaggctggtcttgaactcctaacctcaggtgatccgcccgcctctgccttccaaagtgctgggattacaggcgtgagccactctgcccggcTTATTTTTCTTTATGTTTTTGCTTCGTAAGAGGTTCTGTTGAGcagtgatttgcaactcttgctgacgttgctggggaagctttaaaaaaaaaaaagatgccccacagagattctgattttaattgttctgatttaattggcttggagtagaattcaggcattgatatctttaaaaactccccagTGTTGAGAAACAAATTTAGAGAGTTGAGAAGTAGGTATATTAAATTACAGAATCTTACTGAGTTTTGGTAGACTGATAATACAAtttgctttgcttttcttaaatttgcattgAGATGGGATTTGAAGCATATTGTGCTCTTGTGAATGTTGAAGTTGCATTGTAGAAGTTTAGAAGCTCTGGCTATGGGTTGCCTAAATTGATGTTTTGAGGAAGCATATTAATGTTATAAACTTCGCTGACTTTGAAGGTTGTGTTGTAGCATGAGGAACACAAATAAAACAATTCTAAATCAAACTAA

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