Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NUP58P1
Plot displaying the genomic locations of a retrocopy (in chr4) and its respective parental gene (in chr13). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr4:125681182-125681398  UCSC
Coordinates (T2T) chr4:128983527-128983743  UCSC
Coordinates (hg19) chr4:126602337-126602553  UCSC
Strand -
Parental Sequence NM_001008564.2
Parental seq. overlap 186 bp
Parental seq. overlap (%) 4.4%
Genomic Region Intergenic
Retrocopy Summary NUP58P1, located on chr4:125681182-125681398, is a retrocopy of the parental gene NUP58. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NUP58
Full Name nucleoporin 58
Also known as NUP45|NUPL1|PRO2463
Coordinate chr13:25301084-25349795
Strand +
Gene summary This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NUP58P1
Bonobo Pan paniscus NUP58P1
Orangutan Pongo abelii NUP58P1
Marmoset Callithrix jacchus NUP58P1
Panda Ailuropoda melanoleuca NUP58P1
Gorilla Gorilla gorilla Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NUP58P1
CCACATTTGGATTTGGAAAAATAAATAAACCTTCAGAAATCTTAGTGCAAGCTTTGGCAGCTCAAATAACATCTGCATTTAACTTCAGCAATTCTGGCATCACAGTACCCGTTGGTTGGACATACAGGATGTCTAATCCTGTCTCTGTAGGTTTTGGAACAGGAGGGCAGCTCTTTCAGTTGAAGAAACCTCCAACTGGAAACAAAACAAGAAAAAT
>NM_001008564.2
AGCCTTGCCTTCGCCGCCGTTGGGGCTGGAAGTTCCCGCCAGGTCCGTGCCGGGCGAGAGAGATGCTGCCCGGCCCGCCTCGGCTTTGAGGCGAGAGAAGTGTCCCAGACCCATTTCGCCTTGCTGACGGCGTCGAGCCCTGGCCAGACATGTCCACAGGGTTCTCCTTCGGGTCCGGGACTCTGGGCTCCACCACCGTGGCCGCCGGCGGGACCAGCACAGGCGGCGTTTTCTCCTTCGGAACGGGAGCGTCTAGCAACCCTTCTGTGGGGCTCAATTTTGGAAATCTTGGAAGTACTTCAACTCCAGCAACTACATCTGCTCCTTCAAGTGGTTTTGGAACCGGGCTCTTTGGATCTAAACCTGCCACTGGGTTCACTCTAGGAGGAACAAATACAGGAACGCCAGCCACTACATCTGCAGCTACAACAGGCTTCAGTTTAGGATTCAATAAACCTGCAGCATCTGCCACACCATTTGCTCTACCTATTACCTCTACCTCAGCTAGCGGTCTGACTCTTTCGTCTGCTCTGACATCAACTCCAGCAGCATCCACAGGATTTACTCTAAATAATTTGGGTGGGACAACAGCCACAACTACAACTGCATCAACAGGCCTCTCTTTAGGGGGAGCCTTAGCTGGTTTGGGAGGTTCACTTTTCCAGAGTACAAACACAGGAACATCAGGACTTGGACAGAATGCTTTAGGGTTGACTTTGGGAACTACAGCAGCTACTTCAACTGCAGGCAATGAAGGCCTTGGTGGTATAGATTTCAGTAGCTCCTCAGATAAAAAGAGTGATAAAACGGGAACAAGACCAGAGGATAGTAAAGCTCTGAAGGATGAAAATCTACCTCCTGTCATCTGCCAGGATGTTGAAAATCTCCAGAAATTTGTGAAGGAGCAGAAACAAGTTCAAGAAGAAATTAGTAGAATGTCTTCAAAAGCAATGCTTAAGGTACAAGAAGATATTAAAGCTCTGAAGCAGCTCCTGTCGTTGGCTGCCAATGGAATACAGAGAAACACTCTCAACATTGACAAATTGAAAATAGAAACTGCTCAGGAGTTGAAGAATGCTGAAATAGCTTTAAGAACCCAGAAGACACCACCTGGACTTCAACATGAATATGCAGCTCCTGCTGACTACTTCAGAATCTTGGTTCAGCAATTTGAGGTACAGCTTCAGCAGTACAGGCAGCAGATTGAAGAACTAGAAAACCATCTTGCCACTCAAGCAAATAATTCACATATAACCCCTCAAGATTTGTCAATGGCTATGCAGAAAATTTATCAAACATTTGTAGCTTTAGCGGCACAACTTCAGTCTATTCATGAAAATGTAAAGGTTCTGAAAGAACAGTACCTTGGCTACAGGAAAATGTTCTTGGGAGATGCTGTTGATGTGTTTGAAACAAGGCGAGCAGAAGCCAAGAAGTGGCAGAACACACCCAGAGTTACTACTGGACCCACTCCTTTCAGCACCATGCCAAACGCAGCAGCCGTTGCCATGGCTGCAACACTTACACAGCAGCAACAGCCTGCTACAGGGCCACAGCCATCTCTGGGAGTTAGTTTTGGAACGCCATTCGGCTCAGGTATTGGCACTGGCTTGCAATCAAGTGGCTTAGGTTCTTCAAACCTTGGAGGATTTGGAACTAGCTCTGGTTTTGGATGCAGCACCACAGGGGCCTCCACATTTGGATTTGGAACAACAAATAAACCCTCAGGAAGTCTTAGTGCAGGCTTTGGCAGCTCAAGTACATCTGGGTTTAACTTCAGCAATCCTGGCATCACGGCATCAGCTGGTTTGACTTTTGGGGTGTCCAATCCTGCCTCTGCAGGTTTTGGAACAGGAGGACAACTCCTTCAGTTGAAGAAACCTCCAGCTGGAAACAAAAGAGGAAAAAGATAAACATGGGTTGATGTGTTGAGAGAATCCATAGCAGCACCGTTCATTCTATGAGTCTATTTTTCTAATGATGCAGTAATTAAATTGCATCCCAGGAGATTTATAAAGTTTTGATATTTTTCCCTACTCTGGAATTTGAACTTTCTTCATGTTTGCCATACTGAACATCTTTTTTCTTGTGGAATTTAAAGTCCAGCTGTGTTTTCTTTTTAATTTGATTCTCAGTGTAAGAAATGTTCTGATTACATCACTGATTGGTAATGGTTAGAAACCATTAACCTAAAACTTACTATTTAACCTAGTGTTTTTGTTGATGAGGTTTACATTATGTGAATACATGCACATTTGTTTCTTATACAGGTGGTGTGAACTCTAGGGCCTATACTAGAATCAATTTGTTCCTTGTTAAAGGCCTTTTGAATTATACTGCAGGGCATCTTGTGAATATGTATGTAAATATATACAGAATAATACACACAGTTGTGTGTGCATATAAAATACATATTTACgccaggcgtggtggctcacgcctgtaatcccagcactttgggaggccgaggcaggcggatcacctgaggtcaggagtttgagaccagcctgacatggtgaaaccccatctctacgaaaaatacaaaaattagctgggcatagtggcgggtacctataatcccagctactcgggaggctgaggcacgagaatcacttgaagccgggaggtgggggttgcagtgagccgagatcacaccactgcactccagcctgggcaacaagagcaaaactccgtctcaaaaaagatgaaaataaaataaaaTATATATTTACAGGCCTACAACTTTTGCCTCAGACTGTTCCCCTTTTCTAAGGGTATTCAAGTTTTCACCTTTTAAGCTTCATATCCTCAGTGCTTGTAGAATGATGAGCTTAGAGGTACCAGGTCATTGCAGTTGTTTGCTTAAAGACTTATTGAAATGGTTACTGGCGTAAATACTTGGCCAACTCAACTTTATTGCCCCTGATCTTTTCCATTTTTGTTTCCACCTTAACCTATAGCAGCTCCTCCAAATGAGGAATGCTGTAAGTAAGACTCATCAAACAGATTTTAACCATTTTATTATCCTGTGTGTCCTTACATTGCTTCTGTGAGATGTTTTTTTCTTATCTGAGATGAACTTTCAGGAGCCTATTTGAACTCCAGACTGGTGTTCTGGGGCAAAGAGCTATTAGCCAAACTGATTCTATGCAGGTGAAGGATGCACTAAAGTTCTCACTTTAGTGAGAACTTTTCTAGCTATTCCAATACAGAGTTCTTTCTTATAGGGCTATTGATATTGACACCAAATGGAGTGGCTTCTCAGCCTCTTAATGTCTTAAGTAAGTGCTTAATTTGGAATAGAGAAACCAGTATATTTTAAAAAAGAAAAATATTCTTTGTAGCAACTGTAAATTCTCCCATTATAACAGTGAACAGAGCTCCAGGTAATAACGCATAGGCATGTCAGGTTGCATCTGTATATTTGACTACATTAGTATTAGTGACATCAGGTGGATATAAAAGAAAACCCTTGGAAAGAGAACTGCCTTAGCCATGATTTCGTTAGTAGACCTATTTATGATTCAATTGCAATTTTCAGATAGGATGTGAACATGGAATTTCATTGAAAATAGTTTAATTTTTTATATAAAAGGTTTTGTATATAATGTGTGTCAGTGACTATTTTCAAAATCATTTTCATCAAGACACCTTTTTTCTAAAataggcattgcatacacatatgcacacgtatgtgcatgtgcCACACATTTTTTGTATAATGTTGGGTTTGATTATAAAAGTGTTGTCAAATGTTTTATTTATCTGCATATAGCAGTGGTTGGCTTTTTTGAATTGAAATTTTTGCGCATTGATGCATTGAAATAAGGAAAATTATTTATCTCTGAGCACTAAACTTATTTTTGCATATTTCTGTAATATTGCAGTCCCCAGATCCAGAACATGGGAAGTTAGGGAAAATGTGTGATTTTGTGTTTTGAATTACTGTCAGAATTACATACACAATTACAACAAACTTTTTTTAAAAGACATTTCATTGTACTGCAAAAATCTGAATATTTATATTTCTTGTTTTTTTCTTTATATGTTTTGCATTTTAATATGTTGAGCCACTGGAAATTTGTAACAGATTAATTTGTTATAGGAGTTTAAATGTGTTGTCATTGTCTCCATTGTCTTTGTCCAGAGCCTATTATTATGGAAACAATAAAATTTATTGTGTCAGTTGCTTTGATTCTT

Publications

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