Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ZBTB8OSP1
Plot displaying the genomic locations of a retrocopy (in chr4) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr4:150720974-150722206  UCSC
Coordinates (T2T) chr4:154044902-154046134  UCSC
Coordinates (hg19) chr4:151642126-151643358  UCSC
Strand +
Parental Sequence NM_001366266.1
Parental seq. overlap 713 bp
Parental seq. overlap (%) 35.8%
Genomic Region Intragenic (LRBA)
Retrocopy Summary ZBTB8OSP1, located on chr4:150720974-150722206, is a retrocopy of the parental gene ZBTB8OS. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ZBTB8OS
Full Name zinc finger and BTB domain containing 8 opposite strand
Also known as ARCH|ARCH2
Coordinate chr1:32620818-32651008
Strand -
Gene summary Predicted to enable metal ion binding activity. Involved in tRNA splicing, via endonucleolytic cleavage and ligation. Part of tRNA-splicing ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ZBTB8OSP2
Bonobo Pan paniscus ZBTB8OSP2
Gorilla Gorilla gorilla ZBTB8OSP2
Orangutan Pongo abelii ZBTB8OSP2
Green monkey Chlorocebus sabaeus ZBTB8OSP1
Crab-eating macaque Macaca fascicularis ZBTB8OSP1
Rhesus Macaca mulatta ZBTB8OSP1
Baboon Papio anubis ZBTB8OSP1
Golden snub-nosed monkey Rhinopithecus roxellana ZBTB8OSP1
Marmoset Callithrix jacchus ZBTB8OSP1
Gibbon Nomascus leucogenys Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ZBTB8OSP1
GGCACAGAAAGAGGGAGATGTTAGAGATTACAATTTGACTGAGGAACAGAAGGCGATCAAGGCCAACTATCCTCCAGTTAATAGGAATTATGAGTATTTGGATCATACAGCAGATGTCCAGTTACACACATGGGGAGATACTCTGGAGGAAGCATTTGAGCAATGTGCAATGGCCATATTTGGTTACATGATAGATACCAGGACTGTGGAGCCTCTCCAAACAATAGAAGTAGAAACCCAAGAAGTTTCTACTTTTCTTTTTCACTTTTTAGATGAGTGGCTTTATAAGTCCAATGCTGATGAATTCTTCATACCCTGGGAAGTGAAAGTACTTTGTATTGATCAAAGACATTTCCAATTACAATCAATTGGGTGGAGAGAAGAATTTTCATTGTCCAATCACCCTCAGGGAACCGAAGTCAAAGTTATAACATATTCAGCAATGCAGGTCTATAATAAAGAAAACCCAGAAGTTTTTGTGATCATTGACATTTAAGACCAAAAAAGAAAAGACTCCTAAGAAGAACTGGGTTTTTTTTTTTTCCTCTTCCTTTTGGGAAGACAATGTGAATTAAATTCTATAGTATCTTATGAAATACAGAAATTGTAGAACAAAAACTTATAACTTTATTTATTTACTTAcAGAAATTTACAACTTGAACTGTGACTTTCCAAAATGGAAAATTAGGGCATGTCCTTGGTCTGTGTTCCCCAAATAGTCAATCTTTAAAGAATTCTTCAATTCCTACGGGGCAGTTATGGTCCTTCATTTGTTGATCATCTGCTGTGGCAGCAAGTGCCTCATGCCCTTCCATTGCAATGCAAGCCTTCCACCCTCCCCTCAGAACAGAATGCTGATGTCAGCAGCAGCCTGGTGCTAAATCCAATTTGGAAAAAAAAATAATTTGAGAAAATATATTTCCACACCCAGAA
>NM_001366266.1
AGCCATTTTCTTGAAGGCTATTAAGCTTACGACCCTTTCAGAGTACTGAGATGAAAAATCTAGAATGCCTTCGGGTCTAGTTATCAATTTTGGGGGTGAAGCGGGGGAAAGAACCTCGCCAGTCAGACCCAGACGGGTTTCATTCAAGGTGCCCTTCAACGTTTTTCCTTAGTCTTTGGAAAGAACTAGTAATGAAGGAATCGCAGAAGATGGGGTTTTGGCTTTTTAAATATGCGATCCAAGCGGCAGGGTAGGGACTAAAGTAGGTCAACAGCCAACTCCGAGAAAGGAGTGTGGTCCTTTAAGGGTGTGCGCCAAGGGGCGGAGTCTAGAGCGGAAGTAGTAACTCCGGGCCGAAGTCCGGTGGATGAAGGGCGGAAGTAGAGTGTCTAATCCTGCAGTCATGGCGCAGGAAGAGGAAGATGTTAGAGATTACAATTTGACTGAAGAACAGAAGGCGATCAAGGCCAAGTATCCGCCAGTCAATAGGAAGTACGAGTATTTGGATCATACAGCAGATGTCCAGTTACACGCATGGGGAGATACTCTGGAGGAAGCATTTGAGCAATGTGCAATGGCCATGTTTGGTTACATGACAGATACTGGGACAGTGGAGCCCCTCCAAACAGTAGAAGTAGAAACCCAAGGAGATGACTTACAGTCTCTTCTGTTTCACTTTTTGGATGAATGGCTTTATAAGTTCAGTGCTGATGAATTCTTCATACCCCGGGGAACAGAAGTCAAAGCAATAACATATTCAGCAATGCAGGTCTATAATGAAGAGAACCCGGAAGTTTTTGTGATCATTGACATTTAAGACACCAAAAAATAAAAGACTCCTACGAAGAACTGTTTTTGTTTTCCTCTTCCTTTTGAGAAGACACTATGAATTAAATTCTACAGCTTTTTTTTGATATATGGAAATTTGTAGAACAGAAATATTTTAGTTAAAGTGTGACTTTCAGAAAGGGAAAATCAGGGCACAGCCTTGGTCTGTGTTCCCCAAATATTCACACTTTAAAGAATTCTTCAACCCCCCAAGGGACAGTTATGGTCCTTTGATTCTCTGCTGTGGCAGTAGGTGTGCCTCATGCCCTTCCAGTGCAATGCAAGCCCTCCAGCCTCACCCCAGAGAGGATCACTGATGTCAGCAGCAGCCTGAGGCTGAATCCAGGTTGAAAGAAGAATAACTTGAAAAAATATATTTCCACACACAGAATTTTGTTTTTCTTCCAAGTTGGTTAAGACATATAttttgtttcttttttttttttttttttgagacggagtctcgctctgtagcccaggctgaagcgcagtggtgtgagctcggcttactgcaagctccacctcccgggttcacgccattctcctacctcagcctcccgagtagctgggactataggcacccgccaccatgcccggctaatttttgtatctttagtagagacggggtttcactgtgttagctaggatggtcttgatctcctgaccttgtgatccgcccaccttggcctcccaaggtactgcgattacaggcatgagctaccatgcccggccACAAGACATAGATTTTCTATATGCACATCAAGGGAGGTGCTGGTTTAGGTTGCTATAGGACAGAGCTATCCTGTATTCCAGTTGGTTTTTGTAGAGAAACAATTAGACTTCTCTAGATAGAGCCCTGATTTTTCTCTCACGCTTTCAGTTTTTTAAAAGCACTAATGATATTTCCTGTTTTCTCATAAGAAAAAGTCAATACTATGCCTTACAAAGAGACCTTTCCTTCTAATATAGAATTTTATTTGAAAGTGAGTACATGTTTATAACTAGAGAATAAAAGGAGAATTTTTGAAAAA

Publications

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