Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NOL8P1
Plot displaying the genomic locations of a retrocopy (in chr4) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr4:165547302-165551100  UCSC
Coordinates (T2T) chr4:168893928-168897726  UCSC
Coordinates (hg19) chr4:166468454-166472252  UCSC
Strand -
Parental Sequence XM_006717166.4
Parental seq. overlap 3117 bp
Parental seq. overlap (%) 60.2%
Genomic Region Intergenic
Retrocopy Summary NOL8P1, located on chr4:165547302-165551100, is a retrocopy of the parental gene NOL8. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NOL8
Full Name nucleolar protein 8
Also known as C9orf34|NOP132|bA62C3.3|bA62C3.4
Coordinate chr9:92297358-92325994
Strand -
Gene summary NOL8 binds Ras-related GTP-binding proteins (see MIM 608267) and plays a role in cell growth (Sekiguchi et al., 2004 [PubMed 14660641]).[supplied by OMIM, Mar 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NOL8P1
Bonobo Pan paniscus NOL8P1
Gorilla Gorilla gorilla NOL8P1
Orangutan Pongo abelii NOL8P1
Gibbon Nomascus leucogenys NOL8P1
Green monkey Chlorocebus sabaeus NOL8P1
Crab-eating macaque Macaca fascicularis NOL8P1
Rhesus Macaca mulatta NOL8P1
Baboon Papio anubis NOL8P1
Golden snub-nosed monkey Rhinopithecus roxellana NOL8P1
Marmoset Callithrix jacchus NOL8P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NOL8P1
GGAGGAAGCTGAAAAGCTACGTGAGATGTCCAAAGAAACGTATTATAACATTGCTATGGATCTGAAAGAAATATTTCAAACTTCAAAATATGCCGGTGAAAAGGAAGAGGACACACCCTGGAATGAGGAGTGTGGTAAAGATAAACCTGAGGAAATCCAGGACCCTGCAGCTGACCAGTGGGGCTGAGCAGCCCAGCAGGTTCACATTCTCCTTTTTTGATTCAGACACTAAAGACGTAAAGGAAGAGACCCACAGAGTTGAAACAGTGAAACCTGGAAAGATTGTCTTTCCAGGTTTCTGGAGACGAGGAAGACCCTCGTTTCCAAGACAGCAGTTCAGAAGAGGAAGATGTTACTGAAGGAACAGATCACAGAAAGTCCAGTCCTGGAGAAGCATCATTACCTGAGAAAGAGACCACTAGATTTTTCTTTTTCTCTAAGAATGATGAAAGACTTCAAGTAGAAGTAGGCTCTGATTTATTCTGGAGAGGAGTGGGGAGTAATATTAGCAGGAACTCTTGGGATGCCAGAACAAACAACCTGCGTGTGGATTGTCAGAAGAAACATAAAGATGCAAAAAGGAAAATGAAACCAAAATAACAAATATCAGCACTGGGTTTGATATTGAATGTGAACAAGGCTCACCTTAAGGAAACTGACCCAGAAAATAGTTTTAGCTGACAAAAAAGAAATTTCAGAGTGGAGGAATTTTAAAAATCTGGCTGGTGGAATATCGTTCTGGTTGTCATCTTTTTCTATGGAACTCCTCTGCATTTCTTCCTAAGTAATTACTTCAAAAAATTAAATTCAACTTCTTAAAAAGGAAAGAGAAAATTACTTTTCCCACTAAAACACACCACCAGCTTTCATGAAAGTGAAAGAGAAATGAAGCCCCTTTATGTGGATGGTCTTAGCCAGGAAATTTCTGAAACAGTCCTCCAAAATCAGTTCAGCAGATTTGCAGAAGTTTCAGATGTGGAGATCATCACACGGAAAGATGACCATGGAAACCCACAGAAAGTCTTTGCATATATCAGCATCAGTGTAGCAGAAGCAGACCTGAAAAAATGTATATCCGTTTTAAATAAAACAAAATGGAAAGGTAGAACATTACAAATTCAACTAGCAAAAGAAAGCTTTTTGCACAGATTGGCCCAAGAGAAAGAAGAAGCAAAAGCTAAGAAAGGAAAATCAACAACAGGTAACATCAACTTGTTAGAAAAGATAGGAGGAGTGGAATTCCATATGAAAGCTGCGCCAGGGACAGAAGCGCCAGGGTATAAGAATTGGGTTGTGAGCAAATTTGGAAGAGTGTTACTTGTTCTTCACCTTAAAATTTATCATAAATGTAAAATTATAAAATATGATCCCTCAAAATACTGCCACAACCTAAAGAAGATAGGGGAGGATTTCACAAACACCATTCCTATATCCAGCCTGACTTGGGAACTGGAAGGAGGGAATGACCCTATGAGTAAGAAATGGTGAGGAGACTTCTCTGACTTTCATGGCCCTCCCAAGAAGATGATAAAAGTGCAGAGGGATGAGAGTTCCACTGGGTCTCTGGCCATGAGTCCAAGGCCCAGGTGGGTAATAGAGAGACCACCCTTAACACAGCAACAAGCTGCACAGAAAAAGAACTTCTAATTCCACTACTCCTAAATCATCTCCTGTACCTGTTTCTGATACTCAGAAACTTTAAAATCTACCTTTTAGGACTTCTGGATTGGAAACTGCCAAGAAGAGAAGTGGCATTTCTGATGATTATATTGATTCTAAAGATGAATTAAGAATGATGGTTGCAAAAGAGGAAAACTTACAGAGAACTATACAATCCTCAATAAATGAACCTGAAACTGATCCCTTTGAAGTTGTAAGGGATAACTTCAAATCAGGAGTTCACAAATTGCATTCTTCAACAGGTTTAGGTATCAAAAATAGTGCCTCTTGCCATGACAGTGATGATGATATTACGAGAAATGATTGTGAGTATGACTCAGGAGATACAGAAGAAATCATTGCGATGAAAAAAAATGTTGCTAAGGTCAAAAACAGTACAGAATTTTCACAAATGGAAAAATCTACAGACAAGAAAACTTCCTTCAAAAATAGAGAAAACTGTGAGCTTCTGATCACTGTATTAAAGTACAAGAAAGAAAAAGCAATGTAGAGTCAGCCCTCGGTCATGGATTAAAGGCTCTTAATTGCAAATCTCCCTCTCACTCCAATAGCAATGAAGATGCTGATTCTGCATCAGAATTAGCTGACTCTGAAGGAGACAAGGAGTATAATGCCATGACGAAAAACCGCCTTCGTGTGAATCTCACTTTAGCTGATTTGGAACAATTGGCTGGCAGTGAACAGAAGGTTTCCAATGAAGATACTGAGAGTGACGGGCCAGAAACCACCACACAATGCAAGTTTGACAGAGGCTCCAACAGCCCCAAGACTCCCACTGGCCTCCACAGACGCAGACACTGTATTTGTCCTGACGACACTGTGGCTTTCCTGTTAGAAGGAGAGGAGAGCACCTGTGGCAAACAGAAACCAAAGGAAAACAACTGAAAGCCAGAATTCCAGGTTTTCAAGGGAGTAGGCTGTTTATATGAAAAAGGAGTCAATAAAAAAATCCTTGAAAGACAATGTTGCCTCTAACAATATTAATAAAGATCAGAATTCCATGAAACATGTGGATCCCAGGATCATATCCATGGAAGATGGGTCCCCATATGTTAATGGCTCATCGGGTGAACTGACTCTGTGCCAACATGCAAAGAAGGCGAATGGCCCAACTATATTCAGCCTCAAAAAAGATAGAACACTTCTGAGAGCCAGGATTGCAAGGCAATGTCCACTAGCAGTTCTGAAAAGAGAAGTAAGAATTCTATTTCTAGTTTATTGCCATTAAAAGGTAAGAAGTCCTTAAGTCTTAGTGCAAAGACTCACAACATAGGCTTTGACAAAGACAGCTGCCATAGTACCACAAGACAGAAGCTTCAGAGGAAGAGAGGTCTGACTCAAGCAGCCTCACATCTCTTGAGAAATCACCAAAGTTCTCATCCAAGGACACTCAGGAAATCAAAACTGATTTCTCACTTTCTATTAGTAATTCGTCAGATCTGAGTGCTAAGGATAAGCATGCTGAAGACGATGAGAAGCATTTGGTAGCCTTGGAAGTGAGGCAAAAAGCAAAAGAAGTGCAGAAGAAGCTGGTGGATAATGCTCTGGCAAGTTTGGATGGTCATCCAGAGGATAAACTAACGTACATCATCTTCGGTTCTGACAGTGAATGTGAAACAGAGGAGATATCGACTCAGGAGCAGAGACATCCAGGAGAGGAATGGGTGAAATAGTCTATGGGTAAAACATTGGGGAAGCTGCCTGATAGCAGTGATGATGAGGAATCTGATTCTGAAGATGACAGTAACAGGTTCAAAATTAAACCTCAGTTTGAGGGCAGAGCTGGACAGAAGCTCATGGATTTACAGTCGCACTTTGGCACTGATGACAGATTCTGCATGAATTCTCGATTTCTAGAAAGTGACAGTGAAGACGAACAGGAAGAGGTAAATGAAAAGAAACCCGCTAGGAAGAAGAGCTTGCTGAAGAAAAAAAGAAAGCCTGGATGTTGTACAAAGTGTTTTGAAAATCAACTTAAGCAATTCTACAAAGGATCAGTAGCTGCTAAGAAATTTAAGGGCATCGTACATTATGATCCAACAAAGCAAGACCATGCCACTTATGa
>XM_006717166.4
CGTTGCTGACCGCAGCCGGGCCGGCAGCGCAGCTGTCACTCCGACCTGCGCGCTTCACCCGCGCTTCAAGCCTCGCGCGCGCTCCCGGCGCGGACCATCCCAGAGCTCACGCGGAGGGGAGGCGGGAGAGCTCCGCGTGACCCCAGCGGCCCTGCACGTCCAACTCCGCTCTCGCACGAGAGCCTGAGTCCTCCACTTCCCCGCACACGTTTCCCTGGCTGTCTAAGCAGTGGCTATACTTTCTCTGGAGAGCGCGTTCTTTGCTACTCCAAGCCCAAGCGCTCCGCTGCTCACCCTAGCCGGCAGCCTTGGAGCCGCCCGGCCGCGTGCCTCACTAAAGAGGCAGGGCTGGGATCACGTGGAGGGGAGCGCCTCTTTATTTTTTTCACCTACTTCCTCTCTTACGCCGACCTAGTCCAGGAATTGGTACACACAGCGATAGTGTTCAATAGAAACTAGGGGATTTTGGTTTAGGCTCTTTTGCAGTCGTTGAGGGGGAGGTGACGGAGGCGTCAGGGAAGGTGGGAGGACGGAAAAGGAAATTAAAAGCTCTTGGGAACTGAATTGTGGTAACGGAACCTTAGGAGGCTGGGTTGGAAATCGAGTAGGAAGGAAGAGAGGATGCTCCGTTGGGACACGTGACCAGAAGTTAGGGGCTGCAGCGGCGCTGGCTTTAGGTGAACGACGTGGTGAGGAGTGGGTTTCGGGCATGAGAAGTCACAGGGCCGTTTCCTAGTCTCTCTTCACTTCTTTGGGTCTTCTCAGAGAAAGAAGGCTGCCGTGGGTAGGCTGGGGGCGGAGACTATCGGGAAGAGAAAATTACTTTTCCCACTGAAACACACCCAAGTATATGCCCAGCCTTCATGAAAGTGAACAGAGAAACGAAGCGCCTTTATGTGGGTGGCCTTAGCCAGGACATTTCTGAGGCAGACCTACAAAATCAGTTCAGCAGATTTGGAGAAGTTTCGGATGTGGAGATCATCACACGGAAAGATGACCAAGGAAACCCACAGAAAGTTTTTGCATATATCAACATCAGTGTAGCAGAAGCGGACCTGAAAAAATGTATGTCTGTTTTAAATAAAACAAAATGGAAAGGTGGAACATTACAAATTCAACTAGCAAAAGAAAGCTTTCTGCACAGATTGGCCCAAGAGAGAGAAGCAGCAAAAGCTAAGAAAGAAGAATCAACAACAGGTAACGCCAACTTGTTAGAAAAGACAGGAGGAGTGGATTTCCATATGAAAGCTGTGCCAGGGACAGAAGTGCCAGGGCATAAGAATTGGGTTGTGAGCAAATTTGGAAGAGTCTTACCTGTTCTTCACCTTAAAAATCAACATAAACGTAAAATCATCAAATATGATCCCTCAAAATACTGCCACAACCTGAAGAAGATAGGGGAGGATTTCTCAAACACCATTCCTATATCCAGCCTGACTTGGGAATTAGAAGGAGGGAATGACCCTATGAGTAAGAAACGGCGAGGAGAGTTCTCTGACTTTCATGGCCCTCCCAAGAAGATAATAAAAGTGCAGAAGGATGAGAGTTCCACTGGGTCTCTGGCCATGAGTACAAGGCCCAGGAGGGTAATAGAGAGACCACCCTTAACACAGCAACAGGCTGCACAAAAAAGAACTTGTGATTCCATTACTCCTTCTAAATCATCTCCTGTACCTGTTTCTGATACTCAGAAACTTAAAAATCTACCTTTTAAGACTTCTGGCTTGGAAACTGCCAAGAAGAGAAACAGCATTTCtgatgatgatactgattctgaagatgaattgagaatgatgatTGCGAAAGAGGAAAACTTACAGAGAACTACACAACCCTCAATAAATGAATCTGAAAGTGATCCTTTTGAAGTTGTAAGGGATGATTTCAAATCAGGCGTTCACAAACTGCATTCTTTAATAGGTTTAGGTATCAAAAATCGTGTCTCTTGCCATGATAGTGATGATGATATTATGAGAAATGATCGTGAGTATGACTCAGGAGATACAGATGAAATTATTGCGATGAAAAAAAATGTTGCTAAGGTCAAAAACAGTACAGAATTTTCACAAATGGAAAAATCTACGAAGAAAACTTCTTTCAAAAATAGAGAAAACTGTGAGCTTTCTGATCACTGTATTAAACTACAAAAAAGAAAAAGCAATGTAGAGTCAGCCCTCAGTCATGGATTAAAGTCTCTTAATCGTAAATCTCCCTCTCACTCCAGTAGCAGTGAAGATGCTGATTCTGCATCAGAATTAGCTGACTCTGAAGGAGGTGAGGAGTATAATGCCATGATGAAAAACTGCCTTCGTGTGAATCTCACTTTAGCTGATTTGGAACAATTGGCTGGCAGTGATCTGAAGGTTCCAAATGAAGATACTAAGAGTGATGGACCAGAAACCACCACCCAATGCAAGTTTGACAGAGGCTCCAAGAGCCCCAAGACTCCCACTGGCCTCCGCAGAGGCCGACAGTGTATTCGTCCTGCGGAGATTGTGGCTTCCCTGTTAGAAGGAGAGGAGAACACCTGTGGCAAACAGAAACCAAAGGAAAACAATTTAAAGCCAAAATTTCAGGCTTTCAAGGGAGTAGGCTGTCTATATGAAAAGGAGTCAATGAAAAAATCCTTGAAAGACAGTGTTGCCTCTAACAATAAAGATCAGAATTCCATGAAACATGAGGATCCCAGTATCATATCCATGGAAGATGGGTCCCCATATGTTAATGGCTCATTAGGTGAAGTGACTCCATGCCAACATGCAAAGAAGGCGAATGGCCCAAACTATATTCAGCCTCAAAAAAGACAGACCACTTTTGAAAGCCAGGATCGCAAGGCAGTGTCCCCTAGCAGTTCTGAAAAGAGAAGTAAGAATCCTATTTCTAGGCCATTAGAAGGTAAGAAGTCCTTAAGTCTTAGTGCAAAGACTCACAACATAGGCTTTGACAAAGACAGCTGCCATAGTACCACAAAGACAGAAGCTTCACAGGAAGAGCGGTCTGATTCAAGCGGCCTCACATCTCTCAAGAAATCACCAAAGGTCTCATCCAAGGACACTCGGGAAATCAAAACTGATTTCTCACTTTCTATTAGTAATTCGTCAGATGTGAGTGCTAAAGATAAGCATGCTGAAGACAATGAGAAGCGTTTGGCAGCCTTGGAAGCGAGGCAAAAAGCAAAAGAAGTGCAGAAGAAGCTGGTGCATAATGCTCTGGCAAATTTGGATGGTCATCCAGAGGATAAGCCAACGCACATCATCTTCGGTTCTGACAGTGAATGTGAAACAGAGGAGACATCGACTCAGGAGCAGAGCCATCCAGGAGAGGAATGGGTGAAAGAGTCTATGGGTAAAACATCAGGGAAGCTGTTTGATAGCAGTGATGATGACGAATCTGATTCTGAAGATGACAGTAATAGGTTCAAAATTAAACCTCAGTTTGAGGGCAGAGCTGGACAGAAGCTCATGGATTTACAGTCGCACTTTGGCACCGATGACAGATTCCGCATGGACTCTCGATTTCTAGAAACTGACAGTGAAGAGGAACAGGAAGAGGTAAATGAAAAGAAAACTGCTGAGGAAGAAGAGCTTGCTGAAGAAAAAAAGAAAGCCCTGAATGTTGTACAAAGTGTTTTGCAAATCAACTTAAGCAATTCTACAAACAGAGGATCAGTAGCTGCTAAGAAATTTAAGGACATCATACATTATGATCCAACGAAGCAAGACCATGCCACTTACGAAAGAAAAAGAGATGATAAGCCAAAAGAAAGTAAAGCAAAACGAAAAAAGAAAAGGGAGGAAGCTGAGAAACTACCTGAGGTGTCTAAAGAAATGTATTATAATATTGCTATGGATCTGAAAGAAATATTCCAAACTACAAAATATACCAGTGAAAAGGAAGAGGGCACACCCTGGAATGAGGACTGTGGTAAAGAGAAACCTGAGGAAATCCAGGACCCTGCAGCTCTGACCAGTGACGCTGAGCAGCCCAGCGGGTTCACGTTCTCTTTTTTTGATTCAGACACTAAAGACATAAAGGAAGAGACCTACAGAGTTGAAACAGTGAAACCTGGAAAGATTGTCTGGCAGGAAGACCCTCGTTTACAAGACAGCAGTTCAGAAGAGGAAGATGTTACTGAAGAAACAGATCACAGAAACTCCAGTCCTGGAGAAGCATCATTACTTGAGAAAGAGACCACTAGATTTTTCTTTTTCTCTAAGAATGATGAACGACTTCAAGGTTCTGACTTATTCTGGAGAGGAGTAGGAAGTAATATGAGCAGGAACTCTTGGGAGGCCAGAACAACCAACCTGCGTATGGATTGTCGAAAGAAACATAAAGACGCAAAAAGGAAAATGAAACCAAAATAATAAATGTCAGCTGGTTTTGATACTGAATGTGAACAAGGCTCACCTAAGGAAACTGACCCAGAAAACAGTTTTAGCTGACAAAGAAGAAATTTCAGAGTGAAGGAATTTTAAAAATCTGGCTGACGGAATATCATTCTGGTTGCCATCTTTTTCTGTGGAACTCCTCTGCATTTCTTCCTAAGTAATTACTTCAAAAATTAAATTCAACTTCTTATAAAGGAAGAACAAGATAGTCCTTGAAAATACTTTTTGTATATAATCTCTTTGCCCTCTATCCTGAGTAACTAATGGACATCTTCTCATGCAAGGTTTATATGAAGCCTTTTTAAATAAATGAGTCAAAGCACTTGTATTTTCCAGCCTAGGCTTTGTGTGAATTATAGGCTATTTGAAATTTTATTTCTGATTATGTCAAATACACCTTCCATTTTGTCATTTTTGTTTAAACTGATAAATTACAAGTCAACATTGAGTTTTA

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