Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ICE2P1
Plot displaying the genomic locations of a retrocopy (in chr4) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr4:188386875-188389663  UCSC
Coordinates (T2T) chr4:191734150-191736936  UCSC
Coordinates (hg19) chr4:189308029-189310817  UCSC
Strand -
Parental Sequence NM_024611.6
Parental seq. overlap 2102 bp
Parental seq. overlap (%) 28.7%
Genomic Region Intergenic
Retrocopy Summary ICE2P1, located on chr4:188386875-188389663, is a retrocopy of the parental gene ICE2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ICE2
Full Name interactor of little elongation complex ELL subunit 2
Also known as BRCC1|NARG2
Coordinate chr15:60419609-60479142
Strand -
Gene summary This gene encodes a protein component of the little elongation complex (LEC), which plays a role in small nuclear RNA (snRNA) transcription. The LEC regulates snRNA transcription by enhancing both RNA Polymerase II occupancy and transcriptional elongation. The encoded protein and other LEC components have been shown to localize to Cajal bodies, which are sites of ribonucleoprotein (RNP) complex assembly. Pseudogenes of this gene have been identified on chromosomes 3 and 4. [provided by RefSeq, May 2017]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ICE2P2
Bonobo Pan paniscus ICE2P2
Gorilla Gorilla gorilla ICE2P2
Orangutan Pongo abelii ICE2P2
Gibbon Nomascus leucogenys ICE2P1
Green monkey Chlorocebus sabaeus NARG2P1
Crab-eating macaque Macaca fascicularis ICE2P2
Rhesus Macaca mulatta ICE2P2
Golden snub-nosed monkey Rhinopithecus roxellana ICE2P2
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ICE2P1
AAGTCATGTATTTTTTTTTAAAAAAACCTATCAAATGAGTATATAAAAAATTTGATCCTGTTGGAGAAATTTTTAAAATGCAGGATGAGCTCTTAAAGCCAATTTCCAGAAAAGTACCCAAATTGCCCTTAATGAATTTAGAAAATTCTAAACAGCCCTCTGTTTCTGAGCAACGGTCTGTCCCTTCAGATGCCTCTAGTTGGCCGAAATTGGATGGCCTTCTGCATTTCAGAAGCCAAAAGGACGATTGCCATATGAACTTCAGGACTATGTTGAAGATACGTCGGAATACCTAGCTCCTCAGGAAGGAAACTTTATTCATAAGTTATTTAGCCTGCAAGACCTGTTGTTACTCATGTGCTGCAGTGTCCGGAGGATGGAGACAAGACCACGTTCTAAGAAACAGAAGAAAATCGGAAAACAATTTCCAGTTTATGTACTACCAGAAGTAGAGAATCAAGCTGGTTATGGAGTTGAAGCTCTGACTGAAAGTGAACGTTGTCGCTTGTGGACTGGAAGTTGATTGCATTCCAACAGATATTTTACATTGGCCATATCGATGCATTTACTTCAAAGCTTTTTCTACTGGAAGAAATTACCTCAGAAGCATTAAAAGAAAAGCTTTCAGCACTCAAGATTTCCAATGTATTTAACATTCTCCAACACATTCTAAAGAAATTAAGTAGCTGGCAGGAGGGTTCCTACTTGTTATCTCAGGCAGCAGAAGATTCTTCACTCCCAATCCATAAGACCTCTGATGGAAAAGTTACTAGGACAGCATACAATTTGTATAAAACACATTGCAGCCTTCCTGATGTACCTTCCAGTCTCTCAGTTCTCTGGGTCCGATTAGATCCTAGCCTGTTATGACCATATCATATCCATCATGGAAGAATAACTTGTACTTTTCCACCTAAATCACTGGATACCACAACACAACAAAAGGTTGGTGGAACGAGAATACCTACAGGCAGCCACAGGAATCCAGTTTCCATAGAAACCAAAAGCAGTTGCTTGCCTGCTCAGCAAGTTGAAACTGAAGGAGTGGCTCCGAATAAAAGAATAACTTGAGGACTGCACCGTGGAAAATTAAATTTCAAAAAAAAAAACAAACCCAGTTATAACAATGTTTAATTTAGAAAAGTTTGAGGGAAAATATGACTAAAAGCTCAGTAGGCAAGAGGAACATTTTTCCTGTAGTATCCTCACGAGTTCTTAGAGTGTCTTGAAAAAATATGTTGGCTATGTGAAAGAATGCTTCAACTAAAATGGAATGTTATGCTGTTCACTCCTAAACTTTGAGGAGCATCTTGATATGTTTTAACATTATCATGGCAGGGAAATATATAAAGAAGAAAAATATTTTTACATTAAACCTTTTCTAAAAATTGTAAATAGAAAAATAATTTGATTTTTTATCAAGAATGACACTTATCAATATATATTATGTTATATTGCCAATCTGTTGAGATTGACTCAAAAGGTTAAATATTGCCACTGTTGAAGATAATTATGAGTATCGCAAACCTTGTTTCTGACCCATTTTGATAGTTTCTATATACGCCTTTAAAATGATGAATGTTGCGGGTTAATAAAGTTAATACCTTTAAAACTTGGTGAAATACCATTACAGAAGCCAAAAATAAAAACTCCCTGCCTCTGAAAAATGAAGAGTTTATATCTGAAATGGACATGCCCTGTGAAGTAGTGAGTGCCAAAACACTGAGACTCTTGAAAACTTGTATCTGGATTTTGATGGTGATGTTACAAAACTTGAAACTTTTGGAGTAACCACCACCAAAGCATCAAAGCCAAGAAGTCCAGCAAGTACTTCCACAGTAACTAACGTGACAGATGCTCCTACAGCCCCCAAAGCAGGAACTACACCTGTGGCACCAAGTGCACCAGACATTTCTGCTAATTCTAGAAGTTTATCTCAGATTCTCATTGAACAGTCGCAAAAGGAGAAACAACTGGTCACTGGTATGGATGGTGGCCCTAAAGAGTGCAAAAATAAAGATGACCAGGGATTTGAATCATGTGGCAAAAAGGTATCAAATACTGACAAGTCTTCGAGGCAAGATAGTGACTTGAAAACATCTGATGCCTTACAGTTAGAAAATTCTCAGGAAATTGAAACTGCTAATAAATATGATATGACTATAGATATGGTACATGTTGATGCTGAAAGACCCAATGTTCTGGAAAACCTAGACAACTCAAAGGAAAAGACTGTGACATCAGAAGCAGCTAAAACTGAAGATACAGTTCTCTGCAGCAGTGATACAGATAAGGAGTGTTTAATTATTGATACAGAGTGTAAAAATAATAGTGACGGAAAGACAGCTGTCATGGGTTCCAACTTAAATTCTTGACCAGCTAGCCCAAATTCTTCCTCAGGACAGGCTTCTGCAGAAAACCAGACTAATACTGCTTGTAGTCCAGAAGAGTCATGTGTTTTTAt
>NM_024611.6
GTCATCACGCAGGGCCGAGTCGGCGCGGCCACATCCTTTAAATATGGTCTTTTTTGGGCGCGCGCGACAATGTGAGGAGTGGGGTGGAGCGTGTGTGGTGTGTGGCTGCGGCCTGGGCAAGAGCCGCCGCGGACCATGAGCTGAGTAAGTTCTGGAGGGATCCTGCCTCTTGGAGCCTTCGCAGCCAGGCAGCTGTGAACTGTGAGCTAGAGTGAAGCAGAAATCTAGGAAGATGAGCTCCAAGATGGTCATAAGTGAACCAGGACTGAATTGGGATATTTCCCCCAAAAATGGCCTTAAGACATTTTTCTCTCGAGAAAATTATAAAGATCATTCCATGGCTCCAAGTTTAAAAGAACTACGTGTTTTATCCAACAGACGTATAGGAGAAAATTTGAATGCCTCAGCAAGTTCTGTAGAAAATGAGCCGGCAGTTAGTTCAGCAACTCAAGCAAAGGAAAAAGTTAAAACCACAATTGGAATGGTTCTTCTTCCAAAACCAAGAGTTCCTTATCCTCGTTTCTCTCGTTTCTCACAGAGAGAGCAGAGGAGTTATGTGGACTTGTTGGTTAAATACGCAAAGATTCCTGCAAATTCCAAAGCTGTTGGAATAAATAAAAATGACTACTTGCAGTACTTGGATATGAAAAAACATGTGAACGAAGAAGTTACTGAGTTCCTAAAGTTTTTGCAGAATTCTGCAAAGAAATGTGCGCAGGATTATAATATGCTTTCTGATGATGCCCGTCTCTTCACAGAGAAAATTTTAAGAGCTTGCATTGAACAAGTGAAAAAGTATTCAGAATTCTATACTCTCCACGAGGTCACCAGCTTAATGGGATTCTTCCCATTCAGAGTAGAGATGGGATTAAAGTTAGAAAAAACTCTTCTCGCATTGGGCAGTGTAAAATATGTGAAAACAGTATTTCCCTCAATGCCTATAAAGTTGCAGCTGTCAAAGGACGATATAGCTACCATTGAAACGTCAGAACAAACAGCTGAAGCTATGCATTATGATATTAGTAAAGATCCAAATGCAGAGAAGCTTGTTTCCAGATATCACCCTCAGATAGCTCTAACTAGTCAGTCATTATTTACCTTATTAAATAATCATGGACCAACGTACAAGGAACAGTGGGAAATTCCAGTGTGTATTCAAGTAATACCTGTTGCAGGTTCAAAACCAGTTAAAGTAATATATATTAATTCACCACTTCCCCAAAAGAAAATGACTATGAGAGAGAGAAATCAAATCTTTCATGAAGTTCCATTAAAATTTATGATGTCCAAAAACACATCTGTTCCAGTCTCTGCAGTCTTTATGGACAAACCTGAAGAGTTTATATCTGAAATGGACATGTCCTGTGAAGTCAACGAGTGCCGAAAAATTGAGAGTCTTGAAAACTTGTATTTGGATTTTGATGATGATGTCACAGAACTTGAAACTTTTGGAGTAACCACCACCAAAGTATCAAAATCACCAAGTCCAGCAAGTACTTCCACAGTACCTAACATGACAGATGCTCCTACAGCCCCCAAAGCAGGAACTACAACTGTGGCACCAAGTGCACCAGACATTTCTGCTAATTCTAGAAGTTTATCTCAGATTCTGATGGAACAATTGCAAAAGGAGAAACAGCTGGTCACTGGTATGGATGGTGGCCCTGAGGAATGCAAAAATAAAGATGATCAGGGATTTGAATCATGTGAAAAGGTATCAAATTCTGACAAGCCTTTGATACAAGATAGTGACTTGAAAACATCTGATGCCTTACAGTTAGAAAATTCTCAGGAAATTGAAACTTCTAATAAAAATGATATGACTATAGATATATTACATGCTGATGGTGAAAGACCTAATGTTCTAGAAAACCTAGACAACTCAAAGGAAAAGACTGTTGGATCAGAAGCAGCAAAAACTGAAGATACAGTTCTCTGCAGCAGTGATACAGATGAGGAGTGTTTAATCATTGATACAGAATGTAAAAATAATAGTGATGGAAAGACAGCTGTTGTGGGTTCTAACTTAAGTTCCAGACCAGCTAGTCCAAATTCTTCCTCAGGACAGGCTTCTGTAGGAAACCAGACTAATACTGCTTGTAGTCCTGAAGAGTCATGTGTTTTAAAAAAACCTATCAAACGAGTATATAAAAAATTTGATCCAGTTGGAGAGATTTTAAAAATGCAGGATGAGCTCTTAAAGCCAATTTCCAGAAAAGTACCAGAATTGCCCTTAATGAATTTAGAAAATTCTAAACAGCCTTCTGTTTCTGAGCAATTGTCTGGTCCTTCAGACTCCTCTAGTTGGCCGAAATCTGGATGGCCTTCTGCATTTCAGAAGCCAAAAGGACGATTGCCATATGAACTTCAGGACTATGTTGAAGATACATCGGAATACCTAGCTCCTCAGGAAGGAAATTTTGTTTATAAGTTATTTAGCCTGCAAGACCTGTTGTTACTCGTACGCTGCAGTGTCCAGAGGATAGAGACAAGACCACGTTCTAAAAAACGGAAGAAAATCAGAAGACAATTTCCAGTTTATGTACTACCAAAAGTAGAGTATCAAGCTTGTTATGGAGTTGAAGCTCTGACTGAAAGTGAACTTTGTCGCTTATGGACTGAAAGTTTATTGCATTCCAACAGCTCATTTTATGTTGGGCATATCGATGCATTTACTTCAAAACTTTTTCTACTGGAAGAAATTACCTCAGAAGAATTAAAAGAAAAGCTTTCAGCACTCAAGATTTCCAATTTATTTAACATCCTCCAACACATTCTAAAGAAACTAAGTAGCTTGCAGGAGGGTTCCTACTTGTTATCTCATGCAGCAGAAGATTCTTCACTCCTGATTTATAAGGCCTCTGATGGAAAAGTTACTAGGACAGCATACAATTTGTATAAAACACATTGCGGCCTTCCTGGTGTACCTTCCAGTCTCTCAGTTCCCTGGGTCCCATTAGATCCCAGCCTGTTATTACCATATCATATCCATCATGGAAGAATACCTTGTACTTTTCCACCGAAATCACTGGATACCACAACACAACAAAAGATTGGTGGAACGAGAATGCCTACACGCAGCCACAGGAATCCAGTTTCCATGGAAACCAAAAGCAGTTGCTTGCCTGCTCAGCAAGTTGAAACTGAAGGAGTGGCTCCACATAAAAGAAAAATAACTTGAGGACTGTACCATGGAAAACTAAATTTAAAAAAACAGTTATAACAGTGTTTAATTTAGATAAGTTTGAGGGAAAATAATCAGTAGGCAAGAGGAACATTTTTCCTGTAGTAGCTAGAGTGCCTTGAAAAAATGTGTTGGCTATGTGAAGGAATATTTCAACTAAAATGGAATGGTATGCTTTTCACCCTTGAAGTTTGAGGAGGATCTTGATATGTTTTAACATTATCATGGCAGGGAAATATATAAAGAAGAAAAATATTTTTACATTAAACCTTTTCTAAAAATTGTAAATAGAAAAATAATTTGGTTTTTTATCAAGAACAACACTTATCGTTATGTATTGTGTTAGTTATATTGCCAGTCTGTTGCGACTGACTCAAAAAGTTAAATGTTGCCACTGCTGAAGATGATTATGAGCATCGCAAACTTTGTTTCTGACCCATTTTGACAGTTTTTATATACTCCTTTAAAATGATGAATGTTACAGGTTAATAAAGTTAATACCTTTAAAAACTTGGTGAAATTCCATTACAGAAGCCAAAAATAAAAACTCCCTGCCTCTGAAAAGTCAGATTACTGACTTCTTGTTTGGCAACCATCAGTTTGTTTAATAAAAGAAAAAATTTGGTGGTATAACATGTTTGATGACAGATGCCTCTATCTCTAGATTCAAGCTGAGTGTTGAAATACACTGCTGAAAGCAAAGAGATAGGTATGTTTTCCAGAAAAAAAGTCAGTGTCATTGCTCCAGATGACAAGGTTAATGTGGTAAAGCATAAGCttttttttttttttgagatggagtctcgctctgttgcccaggctggagtgcagtggcatgatctcagctcaccacaacatccacctcctggattaaagcgattctcctgcctcatcctcccgagtagctgggactacaggcacctaccaccaggcttggctaatttttttttgtatttttagtagagacagggtgttaccatgttggccgggctggtctcaaactcctgaccttgtgatccgcctgccttggcctcccaaagtgctgggattacaggggtaagccaccgtgcctggccAGCATAAGCTATTTTTATCCTCATCTATACTGATTGATTTAAATTTTCCGGGCCTGCAGATGAATTTGGAAAAGGGCATAATCAACTGATGTTGCTGTAGCAAATTTGGACTTAAGAAACTACAGACAGggccgggcgtggtggctcacacctgtaattccagcacttcgcaaggccgaggcgggagaatcacttgagtccaggggttggagaccagtctgggcaacacagacctcatctctacaaataaaaaagttagccgggtgtggtggggtgtgcctgtagtcccagctactcaaaaggctgaggcagaagaattgcttgagcccaagaagtcaaggctacagtgagttgtgatcgcaccacagaactcagcttgagtatcagagtgtgaccctgtctcaaagaaaaaaaaaaaCAGGACAGGCTTGTTTAATCTTTAGAACCCTTACACTAAAATTTTCAGAAATTATGTATGTCATTTGTAAAATATAAGTTTTGTAATCCTAGATAATTGCTTCACATTGAAATTTTTTAGCTATTCTGTGTAAAGAATAGCTATTCTTTTGGCCTAATTTCTGAGAAATTAGACCGAAAAATCTCCTCAAGTATTGTAACAGTTGAAAATACTTATATTCAACTACCAAGTTTTGTTTCATTTTGATTTTTTGTTATAAAACATTTTTAAGTTATTTGAGAAGTAATTATTAGTAAAATTGTATCTTGATAAATCATTTCCTCATCCTGCCATTCCCTTTTATAAAACACTGAGTTTTTTTATTCCTTAAGTCACATATCCCAGAAATGTTTTGGTTGTGAATCATTTGCCAGCGAGCCAAGGGAGAGGCAGGGATTCCCTTGAAATGTACTCTTACACTTTTTTATTTTATTTTTAATGTACATTTGTGTGCACCAGAATGGAATGTGCTCTTTTTAAAGAGCTGGACAGTGGTTGCTTCAGACTTCTGAATACCAGAAAGACTTGCCTTTTAATTTTTAAATATTACTTTTTACATCATAAAATGTGTTATCTTATCCATGTATTTGAATAACATCATATATAAAGGTAGTTTTTTGCTTGTGCTTAGTGAAGCCTCCTTTTTTAACATACATTTGATATGCTTTATGTTCTTTTTCTTGATTTTTAGTACTGAGAATTTATAAGCCAAGAAGTAACTGACAATATGTTTAGCAGGAtgtaatcccagctacttgggaagctgaggtgggaggatcgcttgagtctaggagtttgaggctgcagtgagctatgatggtgccactgcactccatcctgggtgagagatcaagaccctatctcaaaaaaTGAGCAAGTTTTTTTTTTTTTTTTAAATCAGACTTAGGGCTAGCAAGGATGTGATCACCCTGGCCCATTTATACCTCAGCAGTGAAGGTGTAATTTATACACACCTCTTTGAAAACAGTTTAATTCAGTAAGTGAGTGCAACTATGTGCCATGCACTCCAAAGTAGGTCCCCACAGTTATTCTCTCATAGCCTTGTTTTTTCAGATCTCACCAtatttatttgtttctttgattttcttttcttatagattacaagctctgcaaggacaggggcatatttgttttgttcaccattaagtaataaacacctaatacagtgcctgtcatgtagttgcttagcagatattagttagatgcatgaatGTGTAGGTATCAAAGATTTTTTTTTTCAGGAGATCACATTCTAGTGGAAGACACTATACTGCTTTATGTGATAAGTGCTTTGATAAAGTAagcaagtcatctaaccagatcttggtagttaaggttttctgagatagaacttgagctgagtcttttaaaaatagtaggatttaTAAGGGAAAATTAAAGGTCTTCCACAAAGAAACTAAGTGAAACTAAGCAGCCTATGAAAAGGTGAAAGTTGGAGAGATTATAGGCTATGAACATGGGAGATGAGAGAGAAAACTGCAGGATAGGGACAGAAACACTGTGCTAAGACATTTGAACTTTGTCCTGTGCAATGTGGGAACCAGTAGTGAAGGTTAATTAACTGACATGATCAGATATGTATTTGAAAAGGGCTCTTGTTGGCATTAGTCTAGAGAATGCGATGGAGCTGGGAAGCGAAAGAAGAAATGTTGGGAGCCTGTGTTGTAGTAACTGAAAAATGGCAATGGCCCAGAATTAAAGCAGCAAGAATAGGAGTGGGCTCAAGTGATGTATAAGGAAAAAAAAAAAAATGACAACTCAGTTTTGTTGTTGGTAAGGAGAGTAAAGTATGGCTTCTGGGTTTCTCATTTGAGATACTGAGTAAATGATGGTGTTAACCCATTGAGAAAATAGTGTGGTTAGAGTGGGAAGAAAGTTAATTTAAAATGTTCATTTTTTTTTTTAGTCATTTCTACTTTTGGATTCTAGGTTTGTGTGCtatattggttataaccaatttgctgaataataaattatcccaaaacttagctacttaaaacaacaaacattatctcacagtttctgtaagtcaaaagtccaggtctctcatgaagttgcagtcaggctcttggctagggctgcagtcatctgaaggattagtaagtcgctaagcccacacttaagctccacccttgaagggagaagtttggaaagaatttgtgaacatatttttaaatcacATATGCTATGAACAGGTTTAGGGGAGGGAGAGGAAAGAAAACTTTAACTTTTCATTAGCATACTGCATCTGTAGTTCCTAATGGGCATGTTGTAAAGATGTTAAGACGTTTTCTATGCATTATAGGTATATAGTAGTAttttgttttgttctgtttttttgtttggtATGTAGTAGTTTTTAATCAAACCTTAACGTATTTGATATTAAGATTTATTGAGTTTCTTGTTGAGATGTAGAAATAAAGGGGATCCATTTCATTTATCCA

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