Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name AGGF1P1
Plot displaying the genomic locations of a retrocopy (in chr4) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr4:190041489-190044282  UCSC
Coordinates (T2T) chr4:193409693-193412484  UCSC
Coordinates (hg19) chr4:190962644-190965437  UCSC
Strand +
Parental Sequence NM_018046.5
Parental seq. overlap 2404 bp
Parental seq. overlap (%) 52.8%
Genomic Region Intergenic
Retrocopy Summary AGGF1P1, located on chr4:190041489-190044282, is a retrocopy of the parental gene AGGF1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name AGGF1
Full Name angiogenic factor with G-patch and FHA domains 1
Also known as GPATC7|GPATCH7|HSU84971|HUS84971|VG5Q
Coordinate chr5:77030404-77065234
Strand +
Gene summary This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes AGGF1P3
Bonobo Pan paniscus AGGF1P2
Gorilla Gorilla gorilla AGGF1P1
Rhesus Macaca mulatta AGGF1P1
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>AGGF1P1
GCCAGGAGCTCCGCACGCAGCTGGAAGAACTCAGTAACGTACTCCGCTGTGGGAGACATGGAGGTAATAAAAGTCTGATGTAGAAGTACTCGCAGAGAACCATGCTCCTTGGTCAATCTCAGATTATTATTATCAGACCTACCCTAATGACGTTAGTCTTCCAAATAAAGTGAGTGACTGAACTGTCAAATCAGCAAGATCAGGATATTGAAAGTCCTGCTTTGAATTCTAACGACCAGTTATAAGTAGAAAATGACACTCACCCTGGTACTGATAGGACAGCAAATGTTAAGTGTAGACAAGAGGGTCATCTGCCTCCAATTCACAGGAGCCAGCATCTGCATTAGCAGCACAAGATACGTCCTTAGAAGGTTCGTCATTAGCTGGAAGTTTGAGAGCTGCAGCGGAAGCGGCTTTGTCACAGACTGGATTTAGTGATGATGAAAATACTGGACTGTATTTTGACCACAGCACTGGTTTCTATTAAGATTCTGAGAATCAAATATATTATGATTTAATTTATTACCACTGTGATGTGGAAAGTTGTCGCTATCGATTTCATTCTCGAGTAGATTTGCAACCTTATCAGACTTATAGCACGAAACAAAAACGAAAAATTGAGAAAAGAAAGGATTCTTCTACAAAAAAACGATGAGGAAAAGGATTTGAATTCAGAGGATCAAGAAGCCTTCAGTGTTGAACATACAAGCTGCAACGGGAAAGACAATTTCACAAATGTGAAAAAAAAAAAGCCAAAATAGGCATTCATCACAAAAATAATCCCCAAAATTCACTGTTCCATTTAGTGGAAATCCTATGGAATCTCCTTTTAATGAAAACATCTCAATTCATCTTTAAGGATGAGAAAATCACAGAGACTGATAGTGAACCAGAAGAAGGTGAAATTACAGACTCTCAGACCGAGGGTAGTTATGATGAAGGCATTACCAGTAAAGGCAATGCAACTGCAAAAGATACTGAGGAGGAAGATGAGGAAAAAGTGTGGCCTCATATATGAGAGTGATTGTCATTAGATCACCTGTGCTACAGACAGGATCATTCTTCATCATTACTGCTGCAAAACCTGCTACAATTGGAAGAGAAAATGATATGGAGCATACTTTCCAAATCCCTGAAGTTGGTGTAAGTTTCATGCAGAAATCTATTTTGACCTTGACTTACAAAGTTATGTCCTTTTGGATCAGACAGTCAAAATGGAACAATTGTTAATGTAAAATGGATTGTTCAGCTGAAAACTAAATGTGAGCCTTATGAACCTGAGCATGGAGATAAAGTGAAAGTTGGAGACACTGTGTTATCTTATTACATTCACACTGGCAGTAATAGCTGTGTTGGATGTGAACCAGGGCAGGTTAGAGCTCACCTTTTCCTTGACAAGAAAGATGAATCATTTGTTGGTCCATCATTAACTAAGAAGGAAACGAGTTGGAAAGAAGAAAAGGATTTTAAAAATATACGAGTAAAATATGGTTTACAGAATACAGACTACAAAGATGATAAGATACTGGAGAATCAAAAATATAAAGATAGAGCTGGAAAACATAGGGAGCAGATTGGAAGTGAAGGAAATTTCCAAAGAGATGATGCTCCTGCATCTGTTCATTCTGAAATTACTGATAGCAACAAAGGTCAGAAGATGTTGAAAAAGATGTGTTGAAAACAGGAGAAGGCCTGGGGAAGGATGGTGGGAGAATAAAAACTCCAGTACAGCTTCAGCCTTGGCAAACACATGCAGGATTGGAGACAGACAAACCATCCTCAATTAAAGAGACTCACCTTCTCCAAAACAAGAACAACAACAACTGGGACAAAGCTCAGGAGAGGTTTGCCGAAAACTTTCCAGAAACTAAACTTCCAAAAGATGACCTAGGAACCATTCCTTGGGTAAAAGGGACTGAGGAGTGAAGGTTAATCACAGAAGAAAACTCAAGCTTTTTTATAAATAGAGTTTGGAAACTCTTATTTTATTGCAGAATGTTTCTCCCCAAAAAAGTCAGTGGCATGAGAAAGCTGTGTCACAGTTTACCCCTTCCTGATTCAGAAATGTGTAATAAAATGTGGTTTGCAGTTTTTAAAAAACACTTTTTAAATTAATTATTAGTGACTGAATTAAGTTATACAGTAAGTGAACTAAAGTTCACAGGGCACAGATAAGTTTACCAAACTTTACTATTTTATCTTGTCATTTACAACATCCATATAAGCAATTAGCCATATAAGCAAAATTCATATAACCACTTAAATGCTCATTTGTCCTTGTCTCCATATATTCATAGTAGTATGCACAGAAAATACAGCAAAAGAAACATCTAAAATCTATAAAAATAAATCTGACAATATACATTCTTTTTTCTGTCCTTCAGGACCTAGATAAAAAATGTGTTGAGACAACATAAATAGTGATGCATACATTTTCTTATATTTGGAATAGCCTAAATCATATTAAAGAACTAATGAACAGGTGACATGTCACAGAAAATTCGTCTTTTATTGTTTTCTTAGGTGAAGAATCTGCATTTGTTGATATATACTGTACATTCAGCATTTGTATTTGGTTTGTTTCATAGCTAATGAAATGTTTATACATGAAAAAATGAGTACAGTATTGAAATAGTCCATGTGCTGGCATTCATACTTTTTATAAATACCATTGCAGGCAATGAAGTTGTGCCAGAAAAATCTGATTTTGAGCACAAAAGGAATACTTAGCCAGGGCCTTGAGCTCAATATATTTATTGAAAATGTCCTAAATTGCCATAAAACATTATAACAT
>NM_018046.5
GCCGTTGTTTCCGGCTCAACTGGGGAGCTGCTGGAGCTCTTCTGGCCTCTGGTTTTCCGACTGCTTATCCGACGCTCCTCCCTCTGTCTCTGTAGCTGGAGAAGGTAGTTTCCAGGAAAGTTTTCCGGTTTGCAGGCCGCGCACATCGGGCAGGGGCCATCCTCGGTCCCCTTGCTCGTTGCTCGCAGCCCCGTTCGGCTACAAGTGAGTTTCAGGGCGTCATGGCCAGGGGCCACCGCGGCCAGCCGGGTGTGAGGCTGCCTTTCGCTGCCCGCGCGCTCCAGTGGTCTCTGGGTCCGCCGGCGTCCGTTTCGGCCTGAACGCAGCCCCTCCGCGGCGACGAGCAGTCTCGCGCCGGAGCTCATGGCCTCGGAGGcgccgtccccgccgcggtcgccgccgccgccCACCTCCCCCGAGCCTGAGCTGGCCCAGCTAAGGCGGAAGGTGGAGAAGTTGGAACGTGAACTGCGGAGCTGCAAGCGGCAGGTGCGGGAGATCGAGAAGCTGCTGCATCACACAGAACGGCTGTACCAGAACGCAGAAAGCAACAACCAGGAGCTCCGCACGCAGGTGGAAGAACTCAGTAAAATACTCCAACGTGGGAGAAATGAAGATAATAAAAAGTCTGATGTAGAAGTACAAACAGAGAACCATGCTCCTTGGTCAATCTCAGATTATTTTTATCAGACGTACTACAATGACGTTAGTCTTCCAAATAAAGTGACTGAACTGTCAGATCAACAAGATCAAGCTATCGAAACTTCTATTTTGAATTCTAAAGACCATTTACAAGTAGAAAATGATGCTTACCCTGGTACCGATAGAACAGAAAATGTTAAATATAGACAAGTGGACCATTTTGCCTCAAATTCACAGGAGCCAGCATCTGCATTAGCAACAGAAGATACCTCCTTAGAAGGCTCATCATTAGCTGAAAGTTTGAGAGCTGCAGCAGAAGCGGCTGTATCACAGACTGGATTTAGTTATGATGAAAATACTGGACTGTATTTTGACCACAGCACTGGTTTCTATTATGATTCTGAAAATCAACTCTATTATGATCCTTCCACTGGAATTTATTACTATTGTGATGTGGAAAGTGGTCGTTATCAGTTTCATTCTCGAGTAGATTTGCAACCTTATCCGACTTCTAGCACAAAACaaagtaaagataaaaaattgaagaagaaaagaaaagaTCCAGATTCTTCTGCAACAAATGAGGAAAAGGATTTGAACTCAGAGGATCAAAAAGCCTTCAGTGTTGAACATACAAGCTGCAATGAGGAAGAAAATTTCGCAAATATGAAAAAGAAGGCCAAAATAGGCATTCATCACAAAAATAGTCCCCCCAAAGTCACTGTTCCAACTAGTGGAAATACTATAGAGTCTCCTCTTCATGAAAACATCTCTAATTCAACATCATTTAAAGATGAGAAAATCATGGAGACTGATAGTGAACCAGAGGAAGGTGAAATTACAGACTCTCAGACTGAGGATAGTTATGACGAAGCCATTACCAGTGAAGGCAATGTAACTGCAGAAGATAGTGAGGATGAAGATGAAGACAAAATTTGGCCCCCATGTATTAGAGTAATTGTCATTAGATCACCTGTGTTGCAGATAGGATCACTCTTTATCATTACTGCTGTAAACCCTGCTACAATTGGAAGAGAAAAGGATATGGAACATACTCTCCGAATCCCTGAAGTTGGTGTCAGTAAGTTTCATGCAGAAATTTATTTTGACCATGACTTACAAAGTTATGTCCTTGTGGATCAAGGCAGTCAAAATGGCACAATTGTTAATGGAAAACAGATTCTTCAGCCGAAAACTAAATGTGACCCTTACGTACTTGAGCATGGAGATGAAGTCAAAATTGGAGAAACTGTCTTATCCTTTCACATTCATCCTGGCAGTGATACCTGTGATGGCTGTGAACCAGGGCAGGTTAGAGCCCACCTTCGCCTTGATAAGAAAGATGAATCTTTTGTTGGTCCAACACTAAGTAAGGAGGAAAAAGAGTTGGAAAGAAGAAAAGAATTAAAGAAAATACGAGTAAAATATGGTTTACAGAATACAGAATACGAAGATGAAAAGACATTGAAGAATCCAAAATATAAAGATAGAGCTGGAAAACGTAGGGAGCAGGTTGGAAGTGAAGGAACTTTCCAAAGAGATGATGCTCCTGCATCTGTTCATTCTGAAATTACTGATAGCAACAAAGGTCGGAAGATGTTGGAGAAGATGGGTTGGAAGAAAGGAGAGGGCCTGGGGAAGGATGGTGGAGGAATGAAAACGCCGATCCAGCTTCAGCTTCGGCGAACACATGCAGGCTTGGGGACAGGCAAACCATCCTCATTTGAAGATGTTCACCTTCTCCAAAACAAGAACAAAAAAAACTGGGACAAAGCACGAGAGCGGTTTACTGAAAACTTCCCAGAAACTAAGCCTCAAAAAGATGACCCAGGGACCATGCCTTGGGTAAAAGGGACTTTAGAGTGAAGGCTAATCATAGAAAAAAAACCTCTAGTTTTTTTAAAAATAGAATTTGGAAACTTATTTTTTCTCCCCAAAAGAATCAGCAGCACAGGGGAACTATGTCACAGTTTACCTCTTCCTGATTCAGAAATGTGTATGGTTTGCAGCTTTTAAAAACCATTTTTTTAAAACTAATAAATAGTGACTGAACCAATTTATGCAGTAAATAGACTAAAGTTCACAGGGCACGGATGAGTTTATCAAACTTCGTTATTTTATCTTGTCATTTACAACATCCATATAAGCAACTAGCCATATAAGCAAAATTCATAGAACTACTAATGACTTAAGTGTACATCTGTTCTTGTCTCCATATATTCATGTAAGATGCACAACAAAAGAAACATCAGAAGTTTATAAAAATAAATCTGACTATATGCATCCTCATTTATTCCCTTTAGAACCTAGGTAAAAAATGTTGCGAAAACATGGGTAGTGGCGCATACATTTTGTTATCCTTGAAATAGCCTAAGTAATGTTATTGAAGAACTAATGAACAGGTAACATATTGTAGAAAATTAGTCTTTCATTGTTTTCTTCTGTGAAGAATCTGTTGCTATGTACTGTATATTCAGCATTTATATTTGGTTTGTTTCATAGCTAATGAGGTATTTAGATATGAACAACTGAATACATATTGAAATAGTGTGCTGGCTTTTGTAGTTTTGATAAAGACCATTGCAGGCAATGGAATTGTGCCAGAGAAATCTGATTTCTAGTACAAAAGGAATACTTAGCCAGGGCCTCAAGCTCAAGATACTTATTGAAAACATCCTCAATTGCAATAAAAACATTATAACATGAAAAAGAGTGATTTTTTGAACCGGTGATTTAAATGTATTGATCTGCTTTGAATTTTCAAGCAGCCAGAATTTTCTAGTTTAAATTGGCAGAGTTATAACAAAGGAGAGCCTCAAATATTAGACAATTGCAGTGCGGCTTTCTGGGCACAGGTGTCACTGCTCTGCCACCTATCACTATTCTTTTTCTGTTCAGTTTTTCTCTCAGGTGTTTGCTGGGAAATTAACACTGGAACTGACCCTTTTCTGGCAGTGAATGTAAGCTCTAGCTCCCCCATCTACTATAAAGAAATGTCTTCGAGATGTAGAAATAAGGAATATTCTGAAAATAAAAATTATACAGTAGTAAAGATAATTCAGAAAGAAAAAGCTACCTGTTAGAATTTCCAGTCTAAATGGCACAGGGTAGTTACGGAGAAAAGGGGATGGAGAAGGAGAAACTATGACTAAAGATGAGAGGTATGAACGAGTTGTCAGGTTCCTATGGGCTTAAGCTAGGACAATCAGGCCCTAAACTCCAAATTTGGATAAAATATCTCTTTGCATTCTTCTTGGCCACCTGCATAGTCTGACACATACGTATGTACAGTTAGACTTGCAGGCTGCAGGAGTGCCCTGCATTGTTTTCTTTTAATTAGAAATAAAAAGTATTAGTCTAAATGTGGTTCTGGTGCTGGTGCCCTGTATATATGTAACAATATAGGACCCCTCCAAATAGGTTTTGCTTCTGGTGAATCTTGGTCATTGGGTTAGTATATGACTGTCTATAATATTTTCCATTTGTATTATTATATTGGGGAAAACATTTTTTATCATTTTCTATTAAGAAAATGGAAAACTTAAATATGGTGTTAAAAATGGAAATATATGTGATATTTGCATTATTAAACCCCTTTGCAGATCTAAAGTCTCAGGGTTCCACTATTAGtggttaaagtactgaataatgtctgggtctatttccatctgtaaaataagaatatttgtctcacgtgtctgtcatgaatagcaaatgagaaaatgtatataaaagcactttgtaaattgtaaaagtagtacagatgtgagCTTCTATTTGTTTAGAAGCATAAATGTGAATTATATACAGTTTGAATTTTGCATAAATTTTTTGTGTCTAATTTTAAA

Publications

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