Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PIMREGP4
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Plot displaying the genomic locations of a retrocopy (in chr4) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr4:26873550-26874381  UCSC
Coordinates (T2T) chr4:26858656-26859487  UCSC
Coordinates (hg19) chr4:26875172-26876003  UCSC
Strand -
Parental Sequence NM_019013.3
Parental seq. overlap 738 bp
Parental seq. overlap (%) 38.6%
Genomic Region Intragenic (STIM2)
Retrocopy Summary PIMREGP4, located on chr4:26873550-26874381, is a retrocopy of the parental gene PIMREG. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PIMREG
Full Name PICALM interacting mitotic regulator
Also known as CATS|FAM64A|RCS1
Coordinate chr17:6444455-6451469
Strand +
Gene summary Predicted to be involved in cell division. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PIMREGP3
Bonobo Pan paniscus PIMREGP2
Gorilla Gorilla gorilla PIMREGP3
Orangutan Pongo abelii PIMREGP3
Gibbon Nomascus leucogenys PIMREGP3
Crab-eating macaque Macaca fascicularis FAM64AP3
Rhesus Macaca mulatta PIMREGP3
Baboon Papio anubis PIMREGP1
Golden snub-nosed monkey Rhinopithecus roxellana PIMREGP2
Marmoset Callithrix jacchus PIMREGP1
Green monkey Chlorocebus sabaeus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Massive Mining of Publicly Available RNA-seq Data from Human and Mouse - (ARCHS4)

Related Sequence

>PIMREGP4
CTAGTGGTCAGACAAGACTCTTGGGCAGGCAGATGGCTTCTCAGCGGCAGGGTGTAGGGGCCTCTGTGCGCCGGAGATCTCTCCAGTACCAGGAGCAGCTCAAGAACAGCAAGGAGCTGCAGCCTGTGGCCAGCCATCCAGGAGACCCCTGCCGCAGCCCTGGGTTCCCTGTGCAGACAGTTCCAAAGGAGGCTGCCCCTGACAGCCATCAACCTCAATCTCTGGGGAGACCCCTCCTGCAAACACTTGGAAACCCCAGAGCCAGGGCAGCAGAGCCTCCAAGCTGCAGCTCGCTCAGCTAAGAGTACCTCAGGTGCCAAGTCCCAGAGAATCCAGGAGTCCTGACACCAAGTGGCTGGTGGAGACTCAGGTGAAGGCCAGGAGGAGAAAGAGAGGGGCACAGAAGAGCAGTGGATCCCTGACTCACAGCCTGAGCCAGAAGAGCACCCAGCTGTCTGGAGGCGCCCCTGTCCACTCAGCCGCAGACCCCTGGGAGAAGGAGCATCACTGCCTCTCTGCCCGGATGGGTTCACGTACCCACCCACTACGGCGGTTGAGGCGGGAGTCTGCCTTGTAGAGCCCCTTACCCCTTGACAGAGCCCCTCTGCTCTCCCAGTGAGTCTGACAGTGACCTAGAGCCTGTGGAGGCAGAAATTCAGCATCTCCAGAAGCTGTCCCAAGAGCTGGATGAAGCCATTATGGCAGAAGAGAGTGGTGACATGAGCGTCTCTCTCATTTATGACTAAGGAAGTGCCCTGCAGGAAACAAGCCCTGTCTGATCACCAAAACTTCACACCCAGTATGTCTGTGCTTCCCCATGAGCTTCCTGGAC
>NM_019013.3
GTGCTGCGGCTGTGCTCGGCCTTAGTGGTGTCGGGGTCTAGTGGACAGAGAAGACTCTTGGCCAGGCAGATGGCTTCTCGGTGGCAGAACATGGGGACCTCCGTGCGCCGGAGATCTCTCCAGCACCAGGAGCAGCTGGAGGACAGCAAGGAGCTGCAGCCTGTGGTCAGCCATCAGGAGACCTCTGTAGGGGCCCTGGGGTCCCTGTGCAGACAGTTCCAAAGGAGGCTGCCCCTGAGAGCCGTCAACCTCAACCTCCGCGCAGGGCCCTCCTGGAAACGCCTGGAAACCCCAGAGCCAGGTCAGCAGGGCCTCCAGGCTGCAGCTCGCTCAGCTAAGAGTGCTTTGGGTGCCGTGTCCCAGAGAATCCAGGAGTCCTGCCAAAGTGGCACCAAGTGGCTGGTGGAGACCCAGGTGAAGGCCAGGAGGCGGAAGAGAGGAGCACAGAAGGGCAGTGGATCCCCAACTCACAGCCTGAGCCAGAAGAGCACCCGGCTGTCTGGAGCCGCCCCTGCCCACTCAGCCGCAGACCCCTGGGAGAAGGAGCATCACCGCCTCTCTGTCCGGATGGGCTCACATGCCCACCCATTACGGCGATCAAGGCGGGAGGCTGCCTTCCGGAGCCCCTACTCCTCAACAGAGCCCCTCTGCTCTCCCAGCGAGTCTGACAGTGACCTAGAGCCTGTGGGGGCGGGAATTCAGCATCTCCAGAAGCTGTCCCAAGAGCTAGATGAAGCCATTATGGCGGAAGAGAGTGGTGACATCGTCTCTCTCATTCATGACTGAGGAAGTGCCTGCAGGAAACAAGCCCTGTCTGACCGCCAAGGCTTCATACTCAAGGATGTCTATGCTTCCCCGTGAGCTTCCTGGAAAAAACCCCCGGGAGTCGTCAGTACCCCTGGGCCACTGCTAACAAGCACCTAACAAGGGGCCCAGAGCCCCCTGCTCCAGCCACATCTGGACCCATCAGTGACTGCCTGCCATAGCCTGAGAGTGTCTTGGGGAGACCTTGCAGAGGGGGAGAATTGTTCCTTCTGCTTTCCTAGGGGACTCTTGAGCTTAGAAACTCATCGTAcacttgaccttgagccttctatttgcctcatctataacatgaagtgctagcatcagatatttgagagctcttagctctgTACCCGGGTGCCTGGTTTTTGGGGAGTCATCCGCAGAGTCACTCACCCACTGTGTTTCTGGTGCCAAGGCTCTTGAGGGCCCCACTCTCATCCCTCCTTTCCCTACCAGGGACTCGGAGGAAGGCATAGGAGATATTTCCAGGCTTACGACCCTGGGCTCACGGGTACCTATTTATATGCTCAGTGCAGAGCACTGTGGATGTGCCAGGAGGGGTAGCCCTGTTCAAGAGCAATTTCTGCCCTTTGTAAATTATTTAAGAAACCTGCTTTGTCATTTTATTAGAAAGAAACCAGCGTGTGACTTTCCTAGATAACACTGCTTTCTCATAATAAAGACTATTTGCATTTGACATCTGTTCCCTTTCACCGGCAACCTCCAACCTCCCCCGCCCTCCCACACCACTCTGGGCTATAGATTTGTAATTTGTGGTTTGGGGTCTGGCCCTCATCCACCTCTGCTCCGAGCCAGTCTGCCCCCAATCCCACCCCAGGGAGAACATGTAGAAAGGGAAAGGTTTCTCAACTTAGTTCAGACCAAAACACATTGTAAAGGCAAAGAAGGTTTTTATTTAAGTGACAACATTTGAGAGCTAAAAACCAGCTCACATCAAAATCAAGACCCAGTTGTAAAAATCTTTTAACTCCATAATGCTGTTTTTGTCTTGTTAGAAATCTGATATCTTACATTAGCGTTTCTAACGGATTTTGTACAAGGCAGCCATAAGGAATATAATAAACCTTTTTCACCACAGAA

Publications

PMID - Link Title
No publications available for this retrocopy