Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DCAF4P1
Plot displaying the genomic locations of a retrocopy (in chr4) and its respective parental gene (in chr14). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr4:41981836-41982992  UCSC
Coordinates (T2T) chr4:41955655-41956811  UCSC
Coordinates (hg19) chr4:41983853-41985009  UCSC
Strand +
Parental Sequence NM_001163508.2
Parental seq. overlap 974 bp
Parental seq. overlap (%) 39.3%
Genomic Region Intergenic
Retrocopy Summary DCAF4P1, located on chr4:41981836-41982992, is a retrocopy of the parental gene DCAF4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DCAF4
Full Name DDB1 and CUL4 associated factor 4
Also known as WDR21|WDR21A
Coordinate chr14:72926337-72962098
Strand +
Gene summary This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2009]

Homology

Species Scientific Name Retrocopy
Bonobo Pan paniscus DCAF4P1
Gorilla Gorilla gorilla DCAF4P1
Orangutan Pongo abelii DCAF4P1
Gibbon Nomascus leucogenys DCAF4P2
Green monkey Chlorocebus sabaeus DCAF4P2
Crab-eating macaque Macaca fascicularis DCAF4P1
Rhesus Macaca mulatta DCAF4P1
Baboon Papio anubis DCAF4P1
Golden snub-nosed monkey Rhinopithecus roxellana DCAF4P1
Marmoset Callithrix jacchus DCAF4P1
Chimpanzee Pan troglodytes Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DCAF4P1
TGAAAAAGGTAGCCAGAATGGGATTTAATGCATCTTCCATGCTCCGAAAAAGCCAGCTAGGTTTCCTCAACGTCACCAGTTACTCCCGTTTAGCCAACGAGCTGCGTGTGAGCTGCATGGAGCGGAAAAAGGTCCAAATTCGGAGCTTGGATCCCTCCTCTTTGGCGAGCGACCGATTTAACTTCATTCTGGCGAGTACCAACAGCGACCAGCTCTTCGTAGTGAACCAGGTCGAAGTCGAAGGCTCCAAGTACGGCATCATCAGCCTGCGAACTCTGAAGATCCCTTCGTTCCACGTGTACGTGCTCAGAAACCTCTACGTCCCCAACCGGAAGGTGAAGTCCCTGTGCTGGGCCTCGCTGAACCAGTTGGACTCTCACGTTCTGCTGTGCTTCGAGGGAATCACAGATGCTCCAAGCTGTGCAGTGCTGCTCCCAGCGTCGCGGTTCTTAAGTGTTCACACAAGAGTTAACCAGCCTGGCATGCTCTGCAGTTTCCAGATCCCAGAGGCCTGGTCCTGTGCGTGGTCCCTCAACACCCGGGCATATCACTGCTTTAGTGCAGGCTTGTCTCAGCAGGTCCTGTTGACCAGCGTGGCGACGGGACACCAGCAGTCATTTGATACCAGCAGTGATGTCTTGGCCCAGCAGTTTGCTAGTACGGCTCCTTTGCTGTTTAATGGCTGTCGCTCCGGGGAGATCTTTGCCATTGATCTGCGTTGTAGAAATCGAGGCAAGGGGTGGAGGGCCACTCGCCTGTTCCATGACTCAGCAGTGACCTCTGTGCAAATCCTCCAAGAAGAGCAATGCCTGATGGCATCAGACATGACTGGAAAGATCAAGCTGTGGGATCTGAGGGCCACTAAATGTGTAAGGCAGTACGAAGGTCACGTGAATGAGTCCGCCTATCTGCCCCTGCATGTGCACGAGGAAGAGGGAATCGTGGTGGCAGTGGGCCAGGACTGCTACACGAGAATCTGGAGCCTCCATGATGCCCACCTGCTCAGAACCATCCCTTCCCCGTACTCTGCCTCCGAGGACGACATTCCCAGCGTGGCCTTCGCTTCTCGGCTCGGGGGCATCCGGGGAGCAGCACCAGGGCTGCTCATGGCTGTCCGGCAGGACCTTTATTGTTTCCCCTTCAGCTAATTCTGCAGG
>NM_001163508.2
CTTTCCGGGTCCTTGCACGCTTCGCTCCAACTCCTGCAGAGCTGAGCCGGAGGGGAATCCGGAAGGGACACGCTGAACAGGAACAGAAATGAATAAAAGTCGCTGGCAGAGTAGAAGACGACATGGGAGAAGAAGCCACCAGCAGAACCCTTGGTTCAGACTCCGTGATTCTGAAGACAGGTCTGACTCCCGGGCAGCACAGCCCGCTCACGATTCCGGCCACGGTGATGACGAGTCTCCGTCAACCTCGTCTGGCACAGCTGGGACCTCCTCTGTGCCAGAGCTACCTGGGTTTTACTTTGACCCTGAAAAGAAACGCTACTTCCGCTTGCTCCCTGGACATAACAACTGCAACCCCCTGACGAAAGAGAGCATCCGGCAGAAGGAGATGGAGAGCAAGAGACTGCGGCTGCTCCAGGAAGAAGACAGACGGAAAAAGATTGCCAGGATGGGATTTAATGCATCTTCCATGCTACGAAAAAGCCAGCTGGGTTTTCTCAACGTCACCAATTACTGCCATTTAGCCCACGAGCTGCGTCTCAGCTGCATGGAGAGGAAAAAGGTCCAGATTCGAAGCATGGATCCCTCCGCCTTGGCAAGCGACCGATTTAACCTCATACTGGCAGATACCAACAGTGACCGGCTCTTCACAGTGAACGATGTTAAAGTTGGAGGCTCCAAGTATGGTATCATCAACCTGCAAAGTCTGAAGACCCCTACGCTCAAGGTGTTCATGCACGAAAACCTCTACTTCACCAACCGGAAGGTGAATTCGGTGTGCTGGGCCTCGCTGAATCACTTGGATTCCCACATTCTGCTATGCCTCATGGGACTCGCAGAGACTCCAGGCTGTGCCACCCTGCTCCCAGCATCACTGTTCGTCAATAGTCACCCAGCAGGAATAGACCGGCCTGGCATGCTCTGCAGTTTCCGGATCCCTGGTGCCTGGTCCTGTGCCTGGTCCCTGAATATCCAAGCAAATAACTGCTTCAGTACAGGCTTGTCTCGGCGGGTCCTGTTGACCAACGTGGTGACGGGACACCGGCAGTCCTTTGGGACCAACAGTGATGTCTTGGCTCCTCTGCTGTTTAATGGCTGCCGCTCTGGGGAAATCTTTGCCATTGATCTGCGTTGTGGAAATCAAGGCAAGGGATGGAAGGCCACCCGCCTGTTTCATGATTCAGCAGTGACCTCTGTGCGGATCCTCCAAGATGAGCAATACCTGATGGCTTCAGACATGGCTGGAAAGATCAAGCTGTGGGACCTGAGGACCACGAAGTGCGTAAGGCAGTACGAAGGCCACGTGAATGAGTACGCCTACCTGCCCCTGCATGTGCACGAGGAAGAAGGAATCCTGGTGGCAGTGGGCCAGGACTGCTACACGAGAATCTGGAGCCTCCACGATGCCCGCCTACTGAGAACCATACCCTCCCCGTACCCTGCCTCCAAGGCCGACATTCCCAGTGTGGCCTTCTCGTCGCGGCTGGGGGGCTCCCGGGGCGCGCCGGGGCTGCTCATGGCTGTCGGGCAGGACCTTTACTGTTACTCCTACAGCTAATTCTGCAGGGCACAGCCCAGAGCCATGTGGATTTGACTTACGGGAGTAAAGCGTAACTTTTTACTGCATCTAATGAGGGTGTTTTAAGTGACACTCAGTGTACACAGATCCCATCCTCTGGCTGCTAGGAGAGAAGTGCTGAATGTTCCGTGTGGAGATGCTCAGGAAAGTTATTTGAGTTAAATTGCTGGCTGAGAGAGCTTGGAAGTCCTTTTCATAAAAGGTACCTCTTTCCTTTTCTTATTGAATTCTTAGAACTTAGTTAACCCTCCCTGCCTTTTCTTAACAAAAAGGACTTTTCTAAGGACTGAAGATTGGCAAAAACGAAAAGCTTCTTCCTCCAAGAGCCCATTGAAGAAGCCCAGTGATGAGACGGTGAGATGGTTTGAGTCCTCGGTGCCTGGGTAGCAGGAAGAAAGACCTGCATCCTGCATCTGTACTTGGGGAAGCCAGCGGAGAGGACGGGGAGGTTACTTCTCTAAGTTTCTGCAGAAATATTGAAGGCTGGAGTTTGGAATCCTTAAACTTGGCCTTCTCAAACTCAGCAGCAGATCTCCGGGATTCTGCTGTTATTATCCAAAGGCGTTGGAAGGAAAGATGGATCTTCTTACATGCTAGAAGTTTTAAACGGTCCTTAACATGCCTTTGTTCAAGCACCTTCCAGAATGTAAGGTTCAGCAGCTCTGGTTTCTATTACGGTGACTTGAATGTCAGATTCAAGGGCCCGGCGTCAAAGGAAATTGGTTTTGACTTTTTGTAATCTAGGAGCGACAGTTCGTGAGATGTTTATTCAGTGTTAAAGAGCCTGTTTTTCTACCAAACAATAAAACCAAGAGAAGAATCATGGTGTGACATGCACTTCTGTGAATGACTTAGGAGATCATGAGCTTGGGCTGCT

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