Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CCDC65P1
Plot displaying the genomic locations of a retrocopy (in chr4) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr4:62489438-62490217  UCSC
Coordinates (T2T) chr4:65926954-65927733  UCSC
Coordinates (hg19) chr4:63355156-63355935  UCSC
Strand -
Parental Sequence NM_001286957.2
Parental seq. overlap 678 bp
Parental seq. overlap (%) 38.5%
Genomic Region Intergenic
Retrocopy Summary CCDC65P1, located on chr4:62489438-62490217, is a retrocopy of the parental gene CCDC65. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CCDC65
Full Name coiled-coil domain containing 65
Also known as CFAP250|DRC2|FAP250|NYD-SP28
Coordinate chr12:48904133-48921576
Strand +
Gene summary This gene encodes a sperm tail protein that is highly expressed in adult testis, spermatocytes and spermatids. The protein plays a critical role in the assembly of the nexin-dynein regulatory complex. Mutations in this gene result in primary ciliary dyskinesia. [provided by RefSeq, Nov 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CCDC65P1
Bonobo Pan paniscus CCDC65P1
Gorilla Gorilla gorilla CCDC65P1
Orangutan Pongo abelii CCDC65P1
Gibbon Nomascus leucogenys CCDC65P1
Green monkey Chlorocebus sabaeus CCDC65P1
Crab-eating macaque Macaca fascicularis CCDC65P1
Rhesus Macaca mulatta CCDC65P1
Baboon Papio anubis CCDC65P1
Golden snub-nosed monkey Rhinopithecus roxellana CCDC65P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CCDC65P1
CCACAGATGATCGAAAGATTGCCTTTGAGACCCTGAAGGTGAAGGATGAGAAGAGCTTTAAAGAAACTAAAGTCCAGATGAAAAAAATACAGAAACTACAGGATGGCATAACCATTTCAAAAGGTAAGATCATGATACACAGCCGTGAGAGTGAAGATGAAAACTGGTATGTCCACAATGACAAGGAATTTGTCCTTGTACAACTGTGAAAACTTAAGCCCAGGCAGCATCCCATGACTTAGTCAAACTCACCCTGGAAAGTAACACTACTCTCAAGGCCCTGATAAAGATTGTTGAGAAAAGGGTGAAAAGATCCTTAAGATTTCTAAAATATGTAGGAAATTTGAATACGAAAAAGAAAAAGGGCTTCATTGTTGTCAGTATTGACTCCTAAGGAGCAGGAGGAGATTGAGGAGAATAACCTAGAAGACCCGAGGAGCTCGCCAAGCTGATGGTGGACTACATAGGGATGGAGAATTTCCAGAAATAGTATGACAAAGTGAAAATGGAGCAACTGAGCCTTCAACACAGACAAGCCCACTGTTAGAAAACAGTGGGAAGCTGTGGGAGATGCTGAAGGAGTACTTCAATGGCATCTCAGTGAGTGACGAAGTGCTGGGCCAAATCAACCCACTGTTCATAGTCATGCGTGGACGCAGCTTACCCTAGCCCTTGTCCACACCTATAGCCCATCCAGGTAACAAACAACATCCAACCACTTACCGTGTCACTGAAGCAGCCCACGTGATCTCTTACACCCTGTGATCTAAGGAAAAAAAA
>NM_001286957.2
AGACGCGTCTTACAGTGGGAGAGCTCAGCCTCACTGATAGCCGGGGATCTCTCCTGTTCGAGGGCTGAGATCTCCGGTCCCACAACCGCCCACAACCAGGGGCACTTCTGGAAGTCCCCTTTCTAGGGACATTTTTCTTCTAAGCTCTGTAACGCGGGCCGAGGCAGACCGAGGCTTCTTTCCCGGATCCAATCCCCTGCCCCCATGCCTAAGAAAGAAAAAATGGCCAAGACGCCCCTGTCCGATGAGAAGCAGCTGCTTCTGTTTCAGCAGAAGTTGCTGGCAGAGGAGGAGATGGCCAAAAAGAAGGAGAGGAACACAACAGTGCTCTGAACCTTAATAAGATTAACACACAGTGGAGAACTGTCCTTCGGGAAGTCAAGACCAGAGAACTTCATAAGGACATTGAGATCCTCAGCCAAACATTTGAACGAGTGGTGGACTGTAAGGACAATGTCATCAAGTCTTTAGCTAAAGACCTGTCCGAAGCCGAGGAGCAGTACGCCCATGCCCTGCGCAGCCACTTGCACAATGTTGACCAGCTCTTGGCCCTGCAGAGGCACCGGCTCAGTCTCCTGGAGGAAAGTTACAACATGGAGCTGGAAGCCCTAACCAAGGAGTTTGAGACAGAAAGGAAGACAATTATTGACCAACATGAGAAAGAGATTCACTATCTGCAAGATATCTTCATGGCCATGGAGCAGAACTATATAGATTCTGAGTATGAAAGCAAGCTGGAGTTCCAGAGCATGTGGAATGATCTCAAAAACATGAATTTAGAAGAGAAGCACTTTCTAAGACTGCACCTGGAGAACAGAGTAGAAGATCTGTGGAGAAAGTTCCAGGATGTACTCAAGAATTACACTGATGCCACAGAGGATCGAAAGGCTGCCTTTGAGACCCTGCAGGTGAAGGATGAGAAGAGCTCCAAAGAGATTGAAGTACAGATGAAAAAAATACAGAAACTACAGGATGCCATAACTATTTCAAAAGGCAAGATCATGATACACAGCCGTGAGAGTGAAGATGAGAACCGGTATATCCGTAATGACAAGGAATTGGTCCTTGTACAACTGCGAAAACTTAAGGCCCAAAGAACTCAGGCCCGGGCAGCATCCCAGAAGAACTTAGTCAGACTCACCCTGGAAAGTAATGCCACCCTCAAGGCCCTGAGAAAGATTGTTGATAAGGGTGAAAAGATCCTTAAACTTGCTGAAATATGTAGGAAATTTGAAACCGAAGAAGAAAAAGTGCTGCCTTTTTATTCATCAGTATTGACTCCTAAGGAGCAGGAGGGGATTCAGAAGAATAATCTAGAAGAGCTTACTGAGGAGCTCACCAAGGTGATGGTGGACTACATAGGAATGGAGAATTTCTGGAAAAGGTACAACAAAGTGAAACTGGAGCAACTGAGCCTCCAACATAGACGAGCCCAGCTGCTAGATATCAATGGGAAGCTGCGGGAGATGCTGAAGCAGTACTTGGATGGCATCTCAGTGAGTGACGAAGTGCTGAGCCAGCTCAACCCACTCTTTATAGTCAACTATCAAAGCAACTTACTCCAGCCCTTGTCCATACGTATAGCCCATCCAGGTGATAAACAACATCCAACCACTTAAAATATAATTGAAGCAGCCCAGATGATCTTCCACAACCTGTGATCTAAGGAAAAAAATCTTTCAACTCCTAGAGATTTTTTTTTTTTTTTGAGAAATGTAGGGATGTTGCTATTAAAAATTTCCATGGAGTTTA

Publications

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