Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name LARP1BP1
Plot displaying the genomic locations of a retrocopy (in chr4) and its respective parental gene (in chr4). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr4:63349850-63351530  UCSC
Coordinates (T2T) chr4:66786541-66788221  UCSC
Coordinates (hg19) chr4:64215568-64217248  UCSC
Strand +
Parental Sequence XM_017008348.1
Parental seq. overlap 1453 bp
Parental seq. overlap (%) 37.1%
Genomic Region Intergenic
Retrocopy Summary LARP1BP1, located on chr4:63349850-63351530, is a retrocopy of the parental gene LARP1B. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name LARP1B
Full Name La ribonucleoprotein 1B
Also known as LARP2
Coordinate chr4:128060655-128222931
Strand +
Gene summary This gene encodes a protein containing domains found in the La related protein of Drosophila melanogaster. La motif-containing proteins are thought to be RNA-binding proteins, where the La motif and adjacent amino acids fold into an RNA recognition motif. The La motif is also found in proteins unrelated to the La protein. Alternative splicing has been observed at this locus and multiple variants, encoding distinct isoforms, are described. Additional splice variation has been identified but the full-length nature of these transcripts has not been determined. [provided by RefSeq, Jun 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes LARP1BP1
Bonobo Pan paniscus LARP1BP1
Gorilla Gorilla gorilla LARP1BP1
Orangutan Pongo abelii LARP1BP1
Gibbon Nomascus leucogenys LARP1BP1
Green monkey Chlorocebus sabaeus LARP1BP2
Rhesus Macaca mulatta LARP1BP1
Baboon Papio anubis LARP1BP1
Golden snub-nosed monkey Rhinopithecus roxellana LARP1BP1
Crab-eating macaque Macaca fascicularis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>LARP1BP1
GTGCCGCCGCTGCTGCGGGATCCATTGGCCTAGGATACCATGGAGGAGGCGGCAGCTGGCCCTAAGGAAAAGCGGCAGCCGCCCCTGCTGCTGCCTAAGGGAAATCCCTGGAACAAAAAGCCTTCACAACACCTGTCCCCAACCACAACAGGTCGGCCGCAGCCAGCGCTGGAAACCCTGGAGGCAGAGTTCGGTTCCCTCAAAATTATGAAAGCAGGAAAACTCAAGAAAAAGAAATCCAACAAGGCTAGTGATTTCAAGGATATGGAGAATTGGCGAACACCAAGTGAATTAGTGAACACTGGATATCAGAGCGTCCTCAGCCACCGGGAAACAAAATTAAATGGTCCTGGTGAAAATGTCAGTGAGGATGAGGCTTAGTCAAGTAATCAACGAAAGAGAGCTAATAAGCACACGTGGGTACCACTCAGATGATGTAAGACCAGAGAGTCAAGAAAGACCTGGATCCTGGAACAGCTCAAGATGTCAACCTGAAGCAAGTAAACCAACACATAACAATAGGAGAAATTATATATGAAATTGGAGGTGAGATAGAGATAAATATGGTTATCAAGAACATGGTGAAAGGACTTTTCAGCCATTTCAAACAGAACTTAATACCAGTATGATGTATTACTATGATGATGGTACAGGGGTACAGGTGTATCGTGTGGAAGAAGCATTGCTTAAAGAGTGTATTAAGCGTCAAATTGAACATTACTTCAATGCAGAAAATTCGGAAAGAGACTACTTTCTTCGAGGAAAGAGGGGTGAACAAGATTCCTTGCCTATTTTCCTGATTGCTGGTTTCCAACGTGTTCAGGCTCTCACTACAAACCTTATCACAGAGGCACTGAAGGATAGCACaCCAGAAAAATGGCCAATTCCAGGCCCTCCTCCATGCAACGTACCACAAACAGACTTCTCTCAACTGATTGTCCAGAGTTTGTACCAGGCTAAGCCTTTTGCTCGCATACAGAGTCTGCCCCAAATTCCCCAAGAATTGGAAGCCCATTGACTCCAAAGAAAAATAGTGAAACAAGTATTCTTCAAGCAATGTCTAGAGATTTGCCAGTTTGCCTGACTTGGACTCAGAACCTGGGATGGAAGTAAAAAAGAGACATCAGCCAGCCCCAGTGAAATTGAGGGAATGAGTGTCTGTTCCTGAGGGGTCATTAAATCAGCTATGTTCTTCAGAAGAAACAGAACAAGAAGAACTTGATTTTTGTTTGATGAAAAGACTGAACAAATAGGATGAAAAAACACATTAACTGATTGGTCTGATAATGATTCAGATTATGAAATTGATGACCAAGACTTAAACAAGATTTTGATTGTAACTCAGACACCACCTTATGTGAAAAAACATCCTGGAGGAGATTGAAGAGGCAACCACATGTCTCAGGCAAAAATCACATCTGAACTTACTAAAGTTATCAATGATGGTTTATATTATTAGGAACAGGATCTATGGATGGAAAAAGATGAAAACAAACATACAGCTGTAAAGGTGAAAATACTGAGAACGCCCTTTCTCATATGAAGGATAAAAACAAGGTTACTATGGA
>XM_017008348.1
CGCCGTCTCCACGCCTCCGCGGGCAGTTACCAGCTTTGGCTGCTCGCGCCTCCCCAACTCGGGTAAAGCTCCTCGGCCTCGGCGTGCTGCGCCTCCGCGGCTGCCCTGCGCCAGGTGAGGGCTCGCGGCTCCCGGCTGCGGCTCCcggcgcgtggtggcgggctcggggcgtgcgtcgcggagaggacggggccggcgggcggttggcgctccgttcggtgcggggaggggcgtcacgccgggcgctgcgcggcctcggcgggcggcggcagcggcggccacggccgccgggcTCTCGGGTTGTCTGTCCCCAGTTGGAGCCGGCCGGTGTCCCGGCGGAGAGACGGGCAGTCGGGTTCCCTGGCCTCGGGGCCACCCCGGCTGGGGCGGCTGGGGCAGAGGGACGATGTCTACTCGCGCCCCGATGCCCGCCGCCCATTCTCGGGAGGATCCGCCCGCGGTGACTGCTGAGAGGGAGTCGCTGTTGGCCGCGGCGAACCGGCCGGCCGAGCAGCCGCCCCCGCCCGAATGTGAGGGCAAAGAGGCGGCGAGGGAGGAGAGGGCCGCGGCCGCCACTAGCGCTGGGGCGCGGGGAGAGCCGTCGCCGGCGCTGGTGCTGGGACGCAGCGTGCCCCAGGCGGCTGTCCCCGTGAGGCCCCTGGCGCTGCACCTGGCGCACAAGGCGCGTGGGCCCGGGGGCCCTTTCGGCGGGGAgccgccaccgccaccgccgccgccgtcgccgttgccgccgttgctgcgggatccgccggccgaggacgccCGGGAAGAGGTGGCAGCTGGCCCTGCGGAAAAGCGGCAGCCGCCGCTGCTGCCGCCTAAGGGAAATCCCTGGACCAAAAAGCCTCCCCAGCACCTGTCCCCAGACACGACAGGTCCGCCACCGCCCCCGCTGGAAACCCTGGAGGCAGAATTCGGTTCCCTCAAAATTATAAAGGCAGGAAAGCTCAAGACAAAGAAATCCAACAAGGCTAGTGATTTCAGTGATATGGAGAATTGGCCAACACCAAGTGAATTAGTGAACACTGGATTTCAGAGCGTCCTCAGCCaaggaaataaaaagccacaaaatagaaaagaaaaagaagagaaggttgaaaagagaagtaacagtgacagcaaagaaaaCCGGGAAACAAAATTAAATGGTCCTGGTGAAAACGTCAGTGAGGATGAGGCTCAGTCAAGTAATCAACGTAAGAGAGCTAATAAGCACAAGTGGGTACCACTCCACTTAGATGTTGTAAGATCAGAGAGTCAAGAAAGACCTGGATCCCGGAACAGCTCAAGATGTCAACCTGAAGCAAATAAACCAACACATAACAATAGGAGAAATGATACACGAAGTTGGAAGCGAGATAGAGAAAAAAGGGATGATCAAGATGACGTTTCCAGTGTGAGAAGTGAGGGTGGTAATATCCGAGGTTCCTTTagaggtcgaggaagaggccgaggacggggaagaggacgaggcagaggaaATCCTCGATTGAACTTTGATTATTCATATGGTTATCAAGAACATGGTGAAAGGACTGATCAACCATTTCAAACAGAACTTAATACCAGTATGATGTATTACTATGATGATGGTACAGGTGTACAGGTGTATCCTGTGGAAGAAGCATTGCTTAAAGAGTATATTAAGCGTCAAATTGAATATTACTTCAGTGTAGAAAATTTGGAACGAGACTTCTTTCTTCGGGGAAAGATGGATGAACAAGGTTTCTTGCCTATTTCCCTGATTGCTGGTTTTCAGCGTGTTCAGGCTCTCACTACAAACCTTAATCTCATCTTAGAGGCACTGAAGGATAGCACAGAAGTAGAAATTGTGGATGAGAAAATGAGAAAAAAGATAGAACCAGAAAAATGGCCAATTCCAGGCCCTCCTCCACGCAGTGTGCCACCAACAGACTTCTCTCAACTGATTGATTGTCCAGAGTTTGTACCAGGCCAAGCCTTTTGCTCACATACAGAGTCTGCCCCAAATTCTCCAAGAATTGGAAGCCCATTGAGCCCAAAGAAAAACAGTGAAACAAGTATTCTTCAAGCAATGTCTAGAGGTTTGTCTACCAGTTTGCCTGACTTGGACTCAGAACCTTGGATAGAAGTTAAAAAAAGACATCAGCCAGCCCCAGTGAAATTGAGGGAATCAGTGTCTGTCCCTGAAGGGTCATTAAATCAGCTATGTTCTTCAGAAGAACCAGAACAAGAAGAACTTGATTTTTTGTTTGATGAAGAGATTGAACAAATAGGACGAAAAAACACATTTACTGATTGGTCTGATAATGATTCAGATTATGAAATTGATGACCAAGACTTAAACAAGATTTTGATTGTAACTCAGACACCACCTTATGTGAAAAAACATCCTGGAGGAGATCGAACAGGCACCCACATGTCTCGGGCAAAAATCACATCTGAACTTGCTAAAGTTATCAATGATGGCTTATACTATTATGAACAGGATCTATGGATGGAAGAAGATGAAAACAAACACACAGCCATAAAGGTGACAATACTGAGAACGCCCTTTCTCGTATGAAAGAATAAAAACAAGTTACTGTGGACAGGCTTAATTTATATGCTCATTGCTTACCTGGCTCTCACCGCAGCTGTATGAGCCAGTGGCTTTAGAGAGCACTCTTCTTGCCTCTTTCTGTTTTCCCCACTTAGTCTATGGTGCATGATCTAAGGTAGTGGAAATGGTTGTGGACAAACTATAAATGACTAAACTGGATGATTATCTCTCTTGGTCTAGTCATTACTGTGGTGCTAGGGTTACTTTTTACAATCTTGTTCTAATTTTTTTTAACTTCTTGCATTTCATCCCAGATCCTGGTTCCTATCCTAGTTATTAAGGTAAAATAGAGAACCAGAATAGTTTATCAGGTATCTGCATTCCTTCAATATGAATTATAATGGTACAGATATGGGGATAAAAGGAATCTTTTTCTGCTATTAAGTTTATCAGAAAAGCCCCAATAGTTAAATATTTGTTTTCAGTAGAGGGTATAATAAGGGAAAATTATATAACATTATATGCCAAATAGGAAACTGATCTTGGTTGGAAATAAAGTTGTAGGAAGAAAAGCTAGCCAATTAGTGGCTGAGTAGAGGGGACTGCCTGTCGGTGGGGCTTCATATCATCAACAAGAAGTGTGCTAGCCTTCTTGGCTCCTCATTTCTTTTCTTCCTGGAATCCCCAGTACTGCTTTTAGCCTTCTGTAACCACTGCCTTCTTGGAGGACCTGCCTCAGGCTATGATAGCTTGTTACGTGACTTAGAGCCTTAGCAGTTCTCTGCCTGTCCTACTGCTGTGGGAAAGGAAGTGTGTTTTTATAATGCTTCTCAGTTGAAAGTCTTTCCTAGTGTAAGCATTGCTATTTTATTTGTAATACTTAGGTTCGGTAAGTAATACCTATCTTAAATCCTTTTAGAACAGAGATACTAGTACATTCTACTAATAATCAGttaaaattatccttcccccattctctatccctttacccagctttgtttttcaccatagcatatatcattatctataattctatatattttacttacttttattctcttggagaaaaaactatggatgtaataccaatgacaataggatttttttctatttgttcattactattgtatttctagtgttagaatagtttctggcacaaagaaatgttcaattcatgtttgtgggtaaataaatTATGGAGTAAACATTATGCATTAACCAAAGGAACCCAACCATTGTGTATAATATTTGTTCTGTGGGAAATGTTTTCAGTCTGCCAAGTAACAAATTTGTAAGCCAACTTGAGAAACATCCTATTTGTAGGTGATTATTTCCTTAAATTATAGACAATAATTAAAAGCCATGTATTGAGTTCTT

Publications

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