Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SRSF10P2
Plot displaying the genomic locations of a retrocopy (in chr4) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr4:77957666-77958697  UCSC
Coordinates (T2T) chr4:81298490-81299521  UCSC
Coordinates (hg19) chr4:78878820-78879851  UCSC
Strand -
Parental Sequence NM_054016.4
Parental seq. overlap 780 bp
Parental seq. overlap (%) 10.1%
Genomic Region Intergenic
Retrocopy Summary SRSF10P2, located on chr4:77957666-77958697, is a retrocopy of the parental gene SRSF10. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SRSF10
Full Name serine and arginine rich splicing factor 10
Also known as FUSIP1|FUSIP2|NSSR|PPP1R149|SFRS13|SFRS13A|SRp38|SRrp40|TASR|TASR1|TASR2
Coordinate chr1:23964347-23980370
Strand -
Gene summary This gene product is a member of the serine-arginine (SR) family of proteins, which are involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein interacts with the oncoprotein TLS, and abrogates the influence of TLS on adenovirus E1A pre-mRNA splicing. This gene has pseudogenes on chromosomes 4, 9, 14, 18, and 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SRSF10P1
Bonobo Pan paniscus SRSF10P1
Gorilla Gorilla gorilla SRSF10P1
Orangutan Pongo abelii SRSF10P1
Gibbon Nomascus leucogenys SRSF10P5
Green monkey Chlorocebus sabaeus SRSF10P3
Crab-eating macaque Macaca fascicularis SRSF10P1
Rhesus Macaca mulatta SRSF10P1
Baboon Papio anubis SRSF10P1
Golden snub-nosed monkey Rhinopithecus roxellana SRSF10P1
Marmoset Callithrix jacchus SRSF10P3
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SRSF10P2
TTGGACTAGTCCTAAATCCAGTGGCTACTGATAGTATAAACCATGATCATTTTTAGGCACGTATCGTTCATTCGCTCATAGATTGGCTTAAATTATCAGGAATACAATGTTTAACAAACACTTGTTAGTTTTCCCTGTACCAGGCAATGGTTATATTAAAATGACATGCTGTTGAGAAGCCACTCTTGAGTCCAGTTTGTTTAGTGCTATGGGCAGCTACCAATTTGTTGTGTCTGTGTATATTTTTGTAAAGATTCTCGTTTTTATGCTTGAAGTATTTGGTGAAAAGATGTTGGTTAACCATAATTTGCAACATTGTCTTACTAAACTTTCATATTAATATTTGGTAGAACTGTTAACCTAGGAAGAAATGAAGGCTAAATCGTGTTCTAGGTCTGCATCGCATGCCAAAACTAGAGGCACCTCTAAAACAGATTCCAAAACATATTACAAGTCTTGCTCAAGACATAAAAAGGAATCAAGGAAAAAAGAACCGCCTTGTTCCAAATCCCATGAATTTGGTCATTATGATCCTATAGTTGATGTGTATGTTCCACTTGATTTCTACACTCACTGTCCAAGAGGAGTTGCTTATGTTCAATTGGAAGATGTTCGTGATGCTGAAGATGCTTTACATAATTTGGACAGAAAGTGGATTTGTGGATGTCAAATGGAAACAGTTTGCACAGGGGGATTGGAAGACCCCAAATCAGATGAAAGCAAAGGAAGGTAGGAGTGTGTACAGTTCTTCACGCTATGATTATGACAGATATAGATGTTCTAGAAGCCAAAGTTATGAAAGAAGATCAAGAAGTCGGTCTTTTGCTTACATCTATAGAAGATCTTGTAGTCCTAGAAAGAGTGGATGGACTGGAAGACCATGGTGTAGCAGAAGCCATTCCAGCAATGATAGAGTCAAACACTGAAATCAGTCTTTTt
>NM_054016.4
GAGGCTCGGCCGCCTGAGCCGCGGACGGTTTGCTGAGCCCGTTAGTGCGCCCGGCCGAGACACGCCGCCGCCATGTCCCGCTACCTGCGTCCCCCCAACACGTCTCTGTTCGTCAGGAACGTGGCCGACGACACCAGGTCTGAAGACTTGCGGCGTGAATTTGGTCGTTATGGTCCTATAGTTGATGTGTATGTTCCACTTGATTTCTACACTCGCCGTCCAAGAGGATTTGCTTATGTTCAATTTGAGGATGTTCGTGATGCTGAAGACGCTTTACATAATTTGGACAGAAAGTGGATTTGTGGACGGCAGATTGAAATACAGTTTGCCCAGGGGGATCGAAAGACACCAAATCAGATGAAAGCCAAGGAAGGGAGGAATGTGTACAGTTCTTCACGCTATGATGATTATGACAGATACAGACGTTCTAGAAGCCGAAGTTATGAAAGGAGGAGATCAAGAAGTCGGTCTTTTGATTACAACTATAGAAGATCGTATAGTCCTAGAAACAGTAGACCGACTGGAAGACCACGGCGTAGCAGAAGCCATTCCGACAATGATAGATTCAAACACCGAAATCGATCTTTTTCAAGATCTAAATCCAATTCAAGATCACGGTCCAAGTCCCAGCCCAAGAAAGAAATGAAGGCTAAATCACGTTCTAGGTCTGCATCTCACACCAAAACTAGAGGCACCTCTAAAACAGATTCCAAAACACATTATAAGTCTGGCTCAAGATATGAAAAGGAATCAAGGAAAAAAGAACCACCTAGATCCAAATCTCAGTCAAGATCACAGTCTAGGTCTAGGTCAAAATCTAGATCAAGGTCTTGGACTAGTCCTAAGTCCAGTGGCCACTGATAGTATAAACCATGGTCATTTTTAGGCATGTATCATTCATTTACTCATAGTTTGGTTTACTTAAATTATCAGGAATACAATGTTGCAATGATGCTTAAAAAACACTTGTTAGTTTTCCCTGTACCAGGCAATGGTTATAATTAAAATGATATGCTGTTGAGAAGCCACTCTTAAGAGTCCAGTTTGTTTAATGTTATGGGCAGCTACCAATTTGTGGTGTCTCTGTATATTTTTGTAAAGATTCTCATTTTTTATGCTTGAAGTATTTGGTGAAAAGATGTTGGTTGACCATAATTTGCAACATTGTCTCATTAAAAATAAACTTTCATATTCATATTTGGTAGAACTGTTAACCTAGAAATGTAGCTTGCTAATAAGATAGAATGATACAAAAGTGAAGTAGTAGCCACAGTACAACACTGACTGCTCAGACACATTTAGGTTCAGGGTGGACCTTTATGTCTTGTCAAGATGTCTAGGCCCggctgggcgtggtggctcacacctgtaatcccagcactttgggaggccgaggcgggcggatcacgaggtcaggagttcgagaccagcctgaccaacacggtgaaaccccgtctctactaaaaatacaaaaattatccgggcatggtggcacatgcctgtaatctcagctactcaggaggctgaggcaagagaatcgcttgaacctgggaggtagaagttgcagtgagccaaaatcacgccactgcactccagcctgggcaacagagtgagactccgtctcaaaaaaaaaaaaaaaCCGGATGTCTAGGCCAATGATAATTATTTTTGATGCAGTGTGGATTAGTTCTTTTGTTAACCCCACTGTCTTGGGGAATGATGCCAGCTGGGAAATTGAGTTTTTGACTGAAACATGGAGCCTTCACTGCTTTTTTTCTGGTTCCTATGAAGATTTGGAACATAGAAAACACAAAAACTCACCTTAAAATTTGAGCAGGTCGTTGATGGCAAAAATAATTTTAAGGAAAAAGGAATATTCTTATGTAGTTATTCTAAAGTTTAAGGAGCGTTGTTGACCATAATATTGCTTAGTTTTCTTACTGCTGTTAAGTAAGTAAATTGTTTCAAAGTAGGTTTTGTGTGTGTGTGCCTAGTGTAAAAGAACTGAAATTTTGATGCTTACAGCACTTGGCTCGTGCATTTGTATCAAAATTTGCCTGCCTCTTTATGAGGGAGGCCTGCTTTTCACACCTCAGTTTATTTAATACGAGGCAAGTTGTAAGACAACACTCATTCTAGGTGATTCTGTGGTGCCATGAAATTTAAGGTAATTTGGGGAAAAGGATTAGTCAGTTTTAAGCAAGAGTCACATCTTTTGAGCTTTCGATTATCAGTGTAGTACCTGACTAAAAATGAAGTAATACCCTTAAACCATTTATAATTTCTAGTATTTCTCTGAAAGATCGTTTTGGGGACAAAAGTGACTTGACATGTCCAATTTCATTTCAGAATAAAAAGCTAGCATCTTTAAAAATCTCAGATTGCTTGCTTACAGATACAAGTACGAATTATGGACAAACGATTCCTTTTAGAGGATTACTTTTTTCAATTTCGGTTTTAGTAATCTAGGCTTTGCCTGTAAAGAATACAACGATGGATTTTAAATACTGTTTGTGGAATGTGTTTAAAGGATTGATTCTAGAACCTTTGTATATTTGATAGTATTTCTAACTTTCATTTCTTTACTGTTTGCAGTTAATGTTCATGTTCTGCTATGCAATCGTTTATATGCACGTTTCTTTAATTTTTTTAGATTTTCCTGGATGTATAGTTTAAACAACAAAAAGTCTATTTAAAACTGTAGCAGTAGTTTACAGTTCTAGCAAAGAGGAAAGTTGTGGGGTTAAACTTTGTATTTTCTTTCTTATAGAGGCTTCTAAAAAGGTATTTTTATATGTTCTTTTTAACAAATATTGTGTACAACCTTTAAAACATCAATGTTTGGATCAAAACAAGACCCAGCTTATTTTCTGCTTGCTGTAAATTAAGCAAACATGCTATAATAAAAACAAAATGAAGGAAATAATGATTAACTGGAATTATTACAGTATTGAATATGATTCTAAAATAACAATGGAAACAGTCCTTTATAGATTTAGGAATATTTTAAATCATTGTTGCACTAGGCACAACTAACTTTTACTTTGGAAATGATAGAACTTGCCAGAAAGGTACATCTTTTACACAGTAGTTAAAAATTCATTGTGTAATATCAAAGTTGTTTCATGATTGCTCATTAAGCCTCTTGGGTTAACTAACTTAAGAGGTTATTTGGTAGTGTTAAGATGAAATTTGGATCAGCTAATTCCAAGTTTATATTTTCATTATTGGATGGATCAGTAATTCTGCTCTCCCTCTTATAAACAAGACGCATTAGGGCTTAACGTTTATGACATGATTTTAAATCATTTTAAATTGAATGTTGATGAGCAACTAATATTAAGTGATAACCTCTTTGGGGAAGTAGGTTAGGTATTTTGTGGTTTGAATTCTATCTACTTTATGACaattatagctaatttattaagtattcatgatgtgccagacacttgaaaaggctatgtgttaactcactcttcacaaaaccttatgagaaagatacttttattttccccatatcacagataaggaaactgaggcacaaagaaaagactgtaaggcagagccaggatttaagcccaggcctggtcccTTAGTTTTGGGGGGGTTTTGTTTGTTTTACAGACTATAATTTGAGAGAAGTAGATTGAGGAGATAGCTCATTGAAATTGTTCATTTTCTGTATAGAACTAGAAGGCCTAATTTCATTTTTATTTTTACTTGTGTCAACTTATTTTTAGACTTGGACTATTGAGAATCTTATATGTTGTTCCTAAAGCGACACACCTAACAGCTTCAAAAGGACTATATTACAGTTGAACCCATGGTAGTTTGGATCCTACTGATACTTGATGAGGATCTTTACGTAGTGTTTTATGTTAGTTTTGGGTGATGTAGTTGAGTCCCCCACTTACTGAGTTTACCTACTGTGTATGACTGGGCTCAATGATAAATAGAATGGTTATATCAACACTCAAATGAGGGCTGACACACTTCACCTCTCCTTTTACTTAAGATCTCTCTGCATTTTTTTTTTTTTTTTGAAGCCAAGTAAGCAAGAAGAAAAATGAGAGATAATGCTTCAGTGAGAGAGGAAAGGTGCTACATAGAGTAtgagctgttaagttacatcccaggggaaagacctgggaactattgtattattctcttgaaaatttggcccagtaagctgctacatccagttcaactaacaaaatcctgtataccacagagaagaataaaggaaaccaaactgacaaacatccttcttttatttaagaccaaactgcagctggaatacccagtacagttctgcttactacacttcaagaaagatctgaaagcggaaaaagaaccaaagaagggcagttcaagcgaccaaagggtgggtggaaggtgctgcagtatgaatactgtacgaatattttgactctggtctgaaaagataaaagAATGTTATCGAAAACtacatggaataattgaagtcccttcaagtttgaaagtaagcattttaggacaaataaaaggaaattcaactttgtacttgtggaaactaatccctaaatatgaataggtttatattgattcatgggtaacaggtccataataaattattggaaactaggatgtctGAATATCAAGGAAGACAGCCATAGTCTCTTACAGTGCCTCTGTTGGTCTGTCTCAAACTGAATTGGGTGGGAAAAGGTATGGTCCAATATAAAAGTTCCATTTTTGCCATTATTggcaaatcttgcctttgtttattttggtgccagtgttttctgcttaatcatttgctttgttggcatctgtgtttatttacttgtacacCACATGCAGTTTACATCTGTCTTAACTACTCCTTCCCAGGTAAATTCCAATTATATTTGACATCCAGCTAAGAGGGCCCATCTCTTCTCACCTCTTTCCTAGTCAGTATattcagcaaatatttattgagcccttactgtgggcaaatcattgtactggATAATTGAGAAAAATAGATAATTCCCTTATTCAGTAAATGTCTACTGAGCACAATCTAGTGAAtcattacagtatggcctcattgttttgtttgaggtgtgttattcataacaatattttacaccattcgtatcaatgtaattatagaacacaatatacgatcaaggataagtaattgtgtggttatctgccatttaaaagtatccagtatttgatcacattattataaataatgaaaaaatgattTAATCTGTAATAAACTGGTTTATTGTGCAGTGACTGTAATATACTAGAGTTATAATAAATTGTTTACTCTGCCTCACCAAACACATGCTAGGATATAACCCCCAAAATAAGTATTTAACTTTGCATTAGGTATAAAGGAGACTGGGTGCTATAATTAGATTATTTTGAGGCAGACAGAGAGCTGTTATCCTAACTGATTTAGTATGTTCTGTAATTGAGAAAATGTTCACCAAATTATACTTTTTAGTGATTTACATGTACATTTTATAGGGGACATGTTCTGTGTATAGCGAATAAATAACTTTTATAGTATCACAAAATGTTTTGGATTCCTTAGTTTCTTATTAGGATATGATGTTTCTTTACCTATACATTGATTTCATCACATTTGATTTTTGTCATCTTTTTTGCCACATACTTAAAATTTTCCATATAAAATTAACTAAAAATCTGGAAGTGGAATTTAAGCTTTTAATTTGTAGCAATTTTGAAAATATAGCAGAGGTATATTTTCAAGGGAGGTGTGAAATGGAGGTATTATTGTTTGTATTTTATTTTAGAAATTTTGTTTGaacttgcccaagatcacacagcaagtgtcagatcctaggttacagcccaTAATTTTTCACTTGTTTCATCTTTTGTTACCATGTTTGTTGTTTAATCCAATGGGGAAGTGTTTTTATAGCTTTATTTTCATGGAGATAGTAACATTGATATAATGGGATCTAGAATTTACTTAGAGTCAAAGTGACTAGATTTAATTACAAAAAGTATTTTGTTGTATACCGTTATACACTCATTAACATAGGGGTTCTTATGGACAGAGGTTCTATGTATTTTTAAAAGAATATGTAGAGGCTATAGACTTTTTTGCCCTCTACCTCCCTTCTCCATTTCCTTTTGAAGTTAAGACATTTAAGGGGGAGAATTAAGGTGCATATTGAGTTGGGGTTTTGTTTAAAAAAAATTAGGTAAATACATATATAACTACAATAACAACAGTTGGTAGTTCTCTAAAATATTTAATTATGGTAAATCAGAAAAGGCCCTTTAATTTTTGCATCTGTTGAATGAATTGCTTTAGGATCTCTTCTGTGGTTGTTTCTCTCTATACTGAATGCTGTCAATAttattgagcacttactgtgccgaaccatgtgcttttcaaatatttctatttaatcctaaaaacactcctgggaaatgggtattattcccattttacagatgagaaaattgTCCTTTGTAGAATACCCATCATGTGATAGCTTCTTGCATATTATGCTATTCATTTCTCACAACCTTACAAGGTAAATGGATAATGTTCCTGGATGAGAGATTAAACGTACTCGAAGATCTTATGGTTGTGTGGCTCAGAGACTCTAAGCATGGCTTTCCAAATCTCATTCTCTTGTAGAGATTTTCCATTGTATTGCATTTTGACCATGTTCCTGTTTACAAAACCTAAGATTATATTCTGAAGTATCTGTGACTTGAGTGATAGCTCAGGAATAATCTGAGGGCATTCTATTAGGAAGGAGGACTAGCAAAGCCTATAGTTAGCCTATCCTAGGCATGAACTATTCTCATTTTAGATAGGATGACTTGATAAATAGGATGAAGTGAGCAACCTGTTTGTCTTCGGTTATTGCTATCTACAAGACATTCTGCTAGTCACTGTGGAAAAGTTTCCTTCTCTTGGGTTTTTTCCTCTTCCCCTTCCTCTTAACAGTGTTGGTTATCTTTATTATGTTTCTGTGTATTTGTAACAGCTGTTTCACCCTTGTATTGCATAATGGGGATTTTTCTTGGAATAAAAAGTGAGGCATGTAAATTCATTGAGAACTAACCGTAGTTTGTAAAGAAGTAAAAGGCCTTTGTATCTAGTTTTTTGCAGATCACATTTCTTTGAATGCTGGAAAGTGAAATAAACTGGTCTAGGAGCCAAAAATAAATCTTGGGTTTTTTTAAGATTTTGCTCTTAGATTTGTAACCACCTGGGTACAACTTTTTCCTAATTTGTGTAAGAGGTTTTAGAGATGCACTCTGTCCCTCTTGCTTTACAAATTGCCTACAAGAATGCAACCAAAATACTAGAAACTGAAACTTACACAAAACCTTTCAGGTTTTTTCCTGTGTTGTAGTTCTAGGGAAGAGGATAGTTTATTAGTATTTATTTTAAGCTTAAGGATAGGTTTTGGACCTGGATTCCATCATAGTATAACTGCCATCGAAAAGAAGACAAATTGAAATTACAGCATTTACCTAAGGTTCACAGTATGGCTGACTTCAGCAGCCTTACATGGTAAGTTCTCTGTACCAGCTATTTTTGGTTCTCGCAATTGCATCGACTTGGGAAATTCCTATCACCATTCTCTATATAGGCTAACCAAAACTTTTATCAGTACCTTT

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