Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ITFG2P1
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:110982778-110984452  UCSC
Coordinates (T2T) chr5:111493403-111495077  UCSC
Coordinates (hg19) chr5:110318477-110320151  UCSC
Strand -
Parental Sequence NM_018463.4
Parental seq. overlap 1533 bp
Parental seq. overlap (%) 65.8%
Genomic Region Intergenic
Retrocopy Summary ITFG2P1, located on chr5:110982778-110984452, is a retrocopy of the parental gene ITFG2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ITFG2
Full Name integrin alpha FG-GAP repeat containing 2
Also known as FGGAP1|KICS3|MDS028
Coordinate chr12:2812663-2826197
Strand +
Gene summary Involved in cellular response to amino acid starvation; cellular response to glucose starvation; and negative regulation of TORC1 signaling. Located in lysosomal membrane. Part of KICSTOR complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ITFG2P1
Bonobo Pan paniscus ITFG2P1
Gorilla Gorilla gorilla ITFG2P1
Orangutan Pongo abelii ITFG2P1
Gibbon Nomascus leucogenys ITFG2P1
Marmoset Callithrix jacchus ITFG2P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ITFG2P1
GGAGATGGGTGTTGTGAGTGGTGGTGGGCTACACAGACTGTGTGGTGTGAGCTTTTTGCTGGGAGGAGCTAGGTGAGGGTCCTGAACATCTGACTGGGCAGCTGGTGTCCCTCAAGAAGTGGTTGCTGGAGGGTCAGGTGGACAGCCTCTCAGTGACTCTGGGGCCGCTGGGTGTTCCTGAACTGATGGTGTCTTAGCCAGGCTGTGCTTATGCAATTCTAACGTGTATGTGGAAAAAGGACACAGGGTCCCCTCCTGCCTCTGAAGGGGTCATGGATGGCAGTAGGGAGACCCTAGCTGCCCGAGATGTGGTACTGCACCAGACATCTGGCCATATCCACAACAAGAATATCTCCACTCACCTAACTGGCAACAACAAACAAGGCCATGGCACTGAGAGTAGTGGCTCTGGCATCTTTGCCGTGAGCACACTGGATGGGATGCTGAAGCTCATGGAGGAAGCAGACAAGCTGTTGTGGTCAGCGCAGGTGGATCACCAGCTCTTCGCCCTGGAGAAATTGGGATGTCAACGGCAATGGGCATGAGGAGGTAGTTCCATGTGCCTGCGATGGACAGACATATATTATTGATCACAATCACACCGTCGTCCGCTTCTAAGTGGATGAAAATATCCGTGCCTTCTATGCAGGCCTGTATGCCTGCCCAGGGATGCAACAGCTCCTGCCTCGTATATGTCACTTTCAACCAGAAGATCTATGTGTACTGGGAGGTGCAGTTGGAGTGGATGGAGTCTACCAATCTGCTGAATGACTGGAGACCAAGCCTGAGTACCATAGCCTGCTGCAGGAGCTGGGCATGGATCCTGACAACCTCCCTGTGGCTCATGCCCTGCTTCACCAAACACTCTACCATCCGACCAACCACCACAGTGTGTTCCCTCAAGCCTCCAGGATCCCACCTAGCTGTACTTGCCTCACAGCTGGTGAAGGATTCTTCTGAACCCCTACCCTACCTCCTCAAGCTATCTTTGATATTGGCAGGATGGGGAATACACATTACAGAAGTGCAGGATTTGACTCTGGGCATGAAAGATGGCAGCAGCCCTAGGGTGACCACAAGCTATACACCTCATGGTCTTTTTGGTGAAAGAAGGGACAAGTTGACCCTTTGCCCATTTTCTTATGGACCTCACCCATCACACCAGCAAGGTCATAGGACCCTGGCCTTGTTCCAGATCATCTGGGACATGTCCCACTCCCCACTTTCACTGTGTAGAAAACAGAGACTTGTTTGCGTGGCCCCAATACCCATAAGGAAACCAGGCTTTAGGCCCAGGGGAGCAGTGGAGGTAAGGGCTCCACCCCATCTTAAGCTCTGTCTTTTATGGCACAATTCCAAGTTCTTAATATTAGTAATTGTTAAAGGAATGGCAAATTGTTTTGTTTTGAGGGGTCTTTCAGTGCAATCTACAATCTGGTCTTACCCATGTTCCTAACAAGCGTGAGATGATTTTCCTCCATTTACCAAAGCACCTGGGTCAGTGCTTTCTCATGTTGCCATATTCTTCAGGTATTAGCTTCAGAAGCCCTGTTCCCATTTTTCCACCCACCCATTCCCCCATAAAATACCTTGTTGTCTGTAAGACAATATACATTTAAAATGTGATGCAGACTTATGATCCAGACCACAATCAGAATTATATCTTGGGCCATTA
>NM_018463.4
GCCTTAGGTGGCCTTCCGCTCTGGCGGCTGTCGCGACGGGGGTTCAGGGAATATTTACTGGGCCTCTCCGCTCCCTCTGCTCTTGGAGGTGCCATGAGGTCAGTTAGCTACGTGCAGCGCGTGGCGCTGGAGTTCAGCGGGAGCCTCTTCCCGCACGCAATCTGCCTCGGAGACGTTGATAACGATACGTTAAATGAACTGGTGGTGGGAGACACCAGCGGGAAGGTGTCTGTGTATAAAAATGATGACAGTCGGCCATGGCTCACCTGTTCCTGCCAGGGAATGCTGACTTGCGTTGGGGTTGGAGACGTGTGTAATAAAGGAAAGAACCTGTTGGTGGCAGTGAGTGCTGAAGGCTGGTTTCATTTGTTTGACCTGACACCTGCCAAGGTGTTGGATGCTTCTGGGCACCACGAGACACTAATCGGAGAGGAGCAGCGTCCAGTCTTCAAGCAGCACATCCCTGCCAACACCAAGGTCATGCTGATCAGCGACATCGATGGAGATGGGTGTCGTGAGCTGGTGGTGGGCTACACAGACCGTGTGGTGCGAGCTTTCCGCTGGGAGGAGCTAGGTGAGGGTCCTGAACATCTGACAGGGCAGCTGGTGTCCCTCAAGAAATGGATGCTGGAGGGTCAGGTGGACAGCCTCTCAGTGACTCTGGGGCCACTGGGTCTTCCTGAACTGATGGTGTCTCAGCCAGGTTGTGCGTATGCAATTCTACTGTGTACCTGGAAAAAGGACACTGGGTCCCCTCCTGCCTCTGAAGGGCCCACGGATGGTAGTAGGGAGACCCCAGCTGCCCGAGACGTGGTGCTGCACCAGACATCTGGCCGTATCCACAACAAGAATGTCTCCACTCACCTAATTGGCAACATCAAACAAGGCCACGGCACTGAGAGTAGTGGCTCTGGCCTCTTTGCCCTGTGCACCCTGGATGGGACACTGAAGCTCATGGAAGAAATGGAAGAAGCAGACAAGCTGCTGTGGTCAGTGCAGGTGGATCACCAGCTCTTTGCCCTGGAGAAACTGGATGTCACCGGCAACGGGCATGAGGAGGTAGTTGCATGCGCCTGGGATGGACAGACATATATCATTGATCACAACCGCACCGTCGTCCGCTTCCAAGTGGATGAAAATATCCGTGCCTTCTGTGCAGGCCTGTACGCCTGCAAAGAGGGCCGCAACAGCCCCTGCCTCGTATATGTCACTTTCAACCAGAAGATCTATGTGTACTGGGAGGTGCAGCTGGAGCGGATGGAGTCTACCAATCTGGTGAAACTGCTGGAGACCAAGCCGGAGTACCACAGCCTGCTGCAGGAGCTGGGCGTGGATCCTGACGACCTCCCTGTGACTCGTGCCCTGCTTCACCAAACGCTCTACCATCCAGACCAGCCACCACAGTGTGCTCCCTCAAGCCTCCAGGATCCCACCTAGCTGTACTTGCCTCATAGCTGGTGAAGGATTCTTCTGAACCCCCACCCTACCCCCTAAAGGTATCTGTGGTATTGGCAGGATAGGGAATATGCATTACAGAAATGCAGGATTTGACTCTGGGCATGAAAGATGGCAGCAGCCCTAGGGTGACCGTGAACTATAGACCTCGCAGTCTTTTCGGTGAAAGAAGAGACAAGTTGACCCTCTGCCCATTTCCTTATGGACCTCACCCATCATGCCAGCAGGGTCATAGGACCCTGGCCTTGTTCCAAATCATCTGGGACATGACCCACTCCCCACTGTCACTGTGTTGAAAACAGAGACTTGTTTGTGTGGCCCCAACACCCATAAGGAAACCAGGCTTTAGGCCCAGGGGAGCAGTGGAGGTAAGGGCTCCACCCCATCTTAAGCTCTGTCTTCCGTGGCACAATTCCAAGTTCTTGACGTTAGTAATTGTTAAAGGAATGGCAAACTGTTTTGTTTTGAAGGATCTTTCTACAGTCTGGTCTTACCCATGTTCCTAGCAACCCTGAGATGATTTTCTTCCATTTACCAAAGCAGCCGGGTCAGTGCTTTCTCACGTTGCCGTATTCTTCAGGTATTAGTCAGCTTCAGAAGCCCTGCTCCCATTTTTCCACCCACCCATTCCCCCATAAAACAGCTTATTGTCTCCAAGACAATAGACATTTAAAATGTGATGCGGGTTTATGATCCAGACCACAATCAGAATTATATCTTGGGTCATTTATGTGCCGTCTGTTCTTGATTCTCTATGCTCTAAATcggtgtttttcaaactgtggttgcagtcctttggtggattatggccagcattttttaaataggtagaatagaataaagtaaaatagaaaatagcagagta

Publications

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