Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TMSB15BP1
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:117019511-117019698  UCSC
Coordinates (T2T) chr5:117531578-117531765  UCSC
Coordinates (hg19) chr5:116355207-116355394  UCSC
Strand -
Parental Sequence NM_001350211.2
Parental seq. overlap 164 bp
Parental seq. overlap (%) 11.7%
Genomic Region Intergenic
Retrocopy Summary TMSB15BP1, located on chr5:117019511-117019698, is a retrocopy of the parental gene TMSB15B. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TMSB15B
Full Name thymosin beta 15B
Also known as TMSB15A|TMSL8|TMSNB|Tbeta15b
Coordinate chrX:103919155-103974426
Strand +
Gene summary Predicted to enable actin monomer binding activity. Involved in positive regulation of cell migration. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes LOC104001050P1
Bonobo Pan paniscus LOC100969885P1
Gorilla Gorilla gorilla LOC101142541P1
Orangutan Pongo abelii LOC100435638P1
Gibbon Nomascus leucogenys LOC100602622P1
Green monkey Chlorocebus sabaeus TMSB15AP1
Crab-eating macaque Macaca fascicularis TMSB15BP2
Rhesus Macaca mulatta TMSB15BP2
Baboon Papio anubis LOC101010496P1
Golden snub-nosed monkey Rhinopithecus roxellana LOC104670020P1
Marmoset Callithrix jacchus TMSB15AP1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TMSB15BP1
CAGGCTTTCTTTAGTCAAGATGAGTTATAAGCCAGACATGTCAAAAGTGGGGAAGTTTGACAGGGAAAAACTGAAGAAAATTAATAACAAAGAAAAAAATACTCTTCTGCCACAGGAAACTATCCAGCAGGAGAAAGAGTATATTCAAACATTCTAAAATGGGATCTCCTCCCAAGGGCAAATTTCAA
>NM_001350211.2
AAGCAGCCTCTGGCCCTGAAGCTACTGCTAGCAAGACTCGGGAGCTGGCTGGCGGGGGCTGAGGCCGACAGGCACGGGAGCCGGCGCGGCGTCAAGTGGAGCTCGGACGCACGGACCAGGCCCATTTCCCTTTCATCTACAGCAATGTTCTTACTCCTCTCCTGCTGTAAAGCCACTCATCTTCGATTTCCCTGAGGACTTCTGCTCCTACAGACTCTCGACGGAGTAAAGCTTCCGATAGAGGGGAAACAGATTCGCTACTAGTGTTGATAGTCAAGTTACTAAGGTTCTTTATCAACGTCTCGGAGCAGATTTGAGAGGCCCCTGAATCGTCCCGGGAATTTTCTTCGGTGAGCATTTGTGGAGACTCTGGGATGTAGGTTGGATTAAACTTCTGTGATGGGTCCATCGGCGTCTTGACACAACACTAAGCTTCTCCTGGATCTTTGAAACGTAGCAGAAACTGATGACGGAGCCTCAAATTGCTACAAGGTAGCCCGGAAAGAGCAAGAGTGAGTGTACTTCGGATGAAGGGAATGTGGACCCTCAGGACTAAAGCAGTGGGAGAGGCCTGGGAGGTGGGGCCTGGGGAGGGCGAGGTCTGCTCTGAAGTCACCAAGCTCCTGATCTTAGAAGAGATGGTGGGCGCAGGCTCTGGAGGCTCAAGCGGAGGAGGGGAAGGAGGCGAGTCCGGAAACCCTCGGCCAATCAGAGAGGGCTGGGGCGGCGCCTGCTAGAAGGCTTAGCACTGCAGGGCTCTGGGCGGGAAGGCTAACCTGGTGCGGAGCCAGCCTGGGTCTCAGCCCCGCGTACGGCCTTTCACGAGTCTTCAAGCCTTCAGGCTTTCTTCTAGTCAAGATGAGTGATAAACCAGACTTGTCGGAAGTGGAGAAGTTTGACAGGTCAAAACTGAAGAAAACTAATACTGAAGAAAAAAATACTCTTCCCTCAAAGGAAACTATCCAGCAGGAGAAAGAGTGTGTTCAAACATCATAAAATGGGGATCTCCTCCAAAGAGCAGATTTCAGCATTGCCTGACAGTCTTGGTTTTAGGCTTGTTTTTTTGTAAACCTGTGTGTTTGTAGAGATTTCAGACATCTTCTGATTTCTTCTCACCTATATTCCCTGGTTAAGAGGTCAGGGGTAGTGAATGTTTCCTTAAGTTCCTTTTTAAACTTCCCATTGGTATGTAAATTCCAAATGGCAGATGCTGTCAATAACCTTGCCATGGATGACCTTTGTGTAGGTAGTCCTTGCACCTCATGCAGGATAAGCCAATTTTAACTTTCTACAATGGGTGCCTCAATAGTTTCATAATCTTCATGAAGTTGCATCCTTTGGCAGCTTCTTACAGTTTATTTTCACTTCCAATGTAGCAATAAAATAATAAATATAA

Publications

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