Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name POGLUT2P1
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr13). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:128109204-128111193  UCSC
Coordinates (T2T) chr5:128628041-128630030  UCSC
Coordinates (hg19) chr5:127444896-127446885  UCSC
Strand +
Parental Sequence NM_024089.3
Parental seq. overlap 1836 bp
Parental seq. overlap (%) 89.3%
Genomic Region Intragenic (SLC12A2)
Retrocopy Summary POGLUT2P1, located on chr5:128109204-128111193, is a retrocopy of the parental gene POGLUT2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name POGLUT2
Full Name protein O-glucosyltransferase 2
Also known as EP58|ERp58|KDEL1|KDELC1
Coordinate chr13:102784281-102799009
Strand -
Gene summary This gene encodes a protein product localized to the lumen of the endoplasmic reticulum. As a member of the endoplasmic reticulum protein family the encoded protein contains a Lys-Asp-Glu-Leu or KDEL motif located at the extreme C-terminus which prevents all endoplasmic reticulum resident proteins from being secreted. Proteins carrying this motif are bound by a receptor in the Golgi apparatus so that the receptor-ligand complex returns to the endoplasmic reticulum. A processed non-transcribed pseudogene located in an intron of a sodium transporter gene on chromosome 5 has been defined for this gene. This gene has multiple transcript variants which are predicted to encode distinct isoforms. [provided by RefSeq, Jan 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes KDELC1P1
Bonobo Pan paniscus POGLUT2P1
Gorilla Gorilla gorilla POGLUT2P1
Orangutan Pongo abelii KDELC1P1
Gibbon Nomascus leucogenys POGLUT2P1
Green monkey Chlorocebus sabaeus KDELC1P1
Crab-eating macaque Macaca fascicularis KDELC1P1
Rhesus Macaca mulatta POGLUT2P1
Baboon Papio anubis POGLUT2P1
Golden snub-nosed monkey Rhinopithecus roxellana POGLUT2P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>POGLUT2P1
TAAGTTCATCATTGTCCTGAGAAAGAGGAGCAGCGCAGTTCTTGGCCGGGTCAGCAGAATCCCTGGTGACCCTCACCTAGGCGTGCCAGGGCACAGGTTGTGATTGTCCTGGGGCGGCGGAAACCCACGTGCCTGCCCTGCATGCCTGCCCTGCATGCCAGGCAGCACGCTTTGGAGTCGCTGTGATTGGCCGGTGTGCCCCTGCCGAAGCCTCGGCTGCTTCTGTCCACGTCTTACACTTCTTCATTTATCCATGGATCATTTCGAGAGTCCGTCTTGTAAATGTTTAGCATTTTGCTGCTTTATTGCTTCTTTCTGGGGACAGTTCCAGCACTTGCTGGGTGGAGAAAGGCAGCTGAGTCCGGAGAAGAGCAAAATATGGGGACCCAGGTTAAAAGCAGACATCGTCCTTCCTACCCAGTATTTCTATATTCAGACAGTGGATACATCAGGGAATAGCTTCACATCTTCTCCAGGCGAAAAAGTCTTCCAGGTGAAAGTCCCAGCACCAGAGGAGCAATTCACTAGAGTTGGAGTCCAGGTTTTAGACTAAAAGGATGGGTCCTTCATGGTAAGATACAGAATGTGTGCAGGCTACAAAAATCTGAAGATGGGAGTTAAATTCCAAGGTCAAGATGTGGCCAAATCCCCATGTATTTTAAAAGAGCCAGTGTGCCATGAGAATTGTGACTGGCCTTTGCAAGATAGTGCAGCCTGGCTACGGGGGATGAACTGCCCAACTGGAAACCATTGCTCAGATTCAGAGAGATCTGGCACATTTCCCTACTGTGGATCCAGAAAAGATTGCAGTAGAAATCCCAAAAAGACTTGGACAGAGGCAGAGCCTGTGTCACTACACCTTAAAAGATAACAAAGTTTATATCAAGTCTCATGGTGAACATGTAGGTTTTAGAATTTTCATGGATGTCATACTACTTTCTTTGACTAGAAAGGTGAAGATGCCAGATGTAGAGTTCTTTGTTAATTTGGCAGACTGGCCTTTGCTTTGGAAAAAAAGAAATCCAATTCAAACATCCATCCGACCTTTTCCTGGTGTGGCTCCACAGATTCCAAGGATATCGTGATGCCTACCTACGACTTGACTGACTGTTTTAGAAACCATGGGCTGGGTAAGTCTGGATATGATGTCTGTGCAAGCTAACACGGGTCCTCCCTGGGAAAGCAAAAACTCCACAGCTGTCTTGAGAGGGCAAGACAGCCGCAAAGGAGACTTGAGCTGGTTAAACTCAGTAGAAACACCCTGAACTCATAGACGCTGCTTTCACCAACTTTTTCTTCTTTAAACATGATGAAAACCTGTATGGTCCCATTGTGAAACACATTTCATTTTTTGATTTCTTCAAGCATAAGTATCAAATAAATATTGATGGCATCGTAGCAGCTTATCACCTGCCATATTTACTAGTTAGTGACAGTGTTGTGCTGAAGCCAAGACTCCGTCTACTATGAACATTTTTACAATGAGCTCTGCAGCCCTGGAAACACTACATTCCAGTGAAGAGCAACCTGAGCGATCTGCTAGAAAAACTTAAATGGACAAAAGATCACAATGAAGAGGCCAAAAAGATAGCAAAAGCAGGACAAGAATTTGCAAGAAATAATCTCATGGATGATGACATATTCTGTTATTATTTCAAACTTTTCCAGGAATATGCCAATTTACAAGTGAGTGGGCCGCAAATCTGAGAGGGCATGAAAAGGGTAGAACCACAGACTGAGAATGACCTCTTCCCTTGCACTTGCCATAGGAAAAAGACCAAAGATGAACTCTGATATGCAAAATAACTTCTATTAAAATAATGGTGCTCTGAAGACTCTTAACTAAAAAGAATTTTTTTAAGTATTAATTCCATGGACAATATAAAATCTGTGTGATTGTTTGCAGTATGAAGATAACGTTTCTACTTATGCAGTATTCTCATGACTGTACTTTACATTTTTAGAATTTTATAATAAAACTACCTTTATT
>NM_024089.3
AAATGATGCTCCAGTGGCAGGAGCAACTCAAGTTCATCATTGTCCTGAGAGAGAGGAGCAGCGCGGTTCTCGGCCGGGACAGCAGAACGCCAGGGGACCCTCACCTGGGCGCGCCGGGGCACGGGCTTTGATTGTCCTGGGGTCGCGGAGACCCGCGCGCCTGCCCTGCACGCCGGGCGGCAACCTTTGCAGTCGCGTTGGCTGCTGCGATCGGCCGGCGGGTCCCTGCCGAAGGCTCGGCTGCTTCTGTCCACCTCTTACACTTCTTCATTTATCGGTGGATCATTTCGAGAGTCCGTCTTGTAAATGTTTGGCACTTTGCTACTTTATTGCTTCTTTCTGGCGACAGTTCCAGCACTCGCCGAGACCGGCGGAGAAAGGCAGCTGAGCCCGGAGAAGAGCGAAATATGGGGACCCGGGCTAAAAGCAGACGTCGTCCTTCCCGCCCGCTATTTCTATATTCAGGCAGTGGATACATCAGGGAATAAATTCACATCTTCTCCAGGCGAAAAGGTCTTCCAGGTGAAAGTCTCAGCACCAGAGGAGCAATTCACTAGAGTTGGAGTCCAGGTTTTAGACCGAAAAGATGGGTCCTTCATAGTAAGATACAGAATGTATGCAAGCTACAAAAATCTGAAGGTGGAAATTAAATTCCAAGGGCAACATGTGGCCAAATCCCCATATATTTTAAAAGGGCCGGTTTACCATGAGAACTGTGACTGTCCTCTGCAAGATAGTGCAGCCTGGCTACGGGAGATGAACTGCCCTGAAACCATTGCTCAGATTCAGAGAGATCTGGCACATTTCCCTGCTGTGGATCCAGAAAAGATTGCAGTAGAAATCCCAAAAAGATTTGGACAGAGGCAGAGCCTATGTCACTACACCTTAAAGGATAACAAGGTTTATATCAAGACTCATGGTGAACATGTAGGTTTTAGAATTTTCATGGATGCCATACTACTTTCTTTGACTAGAAAGGTGAAGATGCCAGATGTGGAGCTCTTTGTTAATTTGGGAGACTGGCCTTTGGAAAAAAAGAAATCCAATTCAAACATCCATCCGATCTTTTCCTGGTGTGGCTCCACAGATTCCAAGGATATCGTGATGCCTACGTACGATTTGACTGATTCTGTTCTGGAAACCATGGGCCGGGTAAGTCTGGATATGATGTCCGTGCAAGCTAACACGGGTCCTCCCTGGGAAAGCAAAAATTCCACTGCCGTCTGGAGAGGGCGAGACAGCCGCAAAGAGAGACTCGAGCTGGTTAAACTCAGTAGAAAACACCCAGAACTCATAGACGCTGCTTTCACCAACTTTTTCTTCTTTAAACACGATGAAAACCTGTATGGTCCCATTGTGAAACATATTTCATTTTTTGATTTCTTCAAGCATAAGTATCAAATAAATATCGATGGCACTGTAGCAGCTTATCGCCTGCCATATTTGCTAGTTGGTGACAGTGTTGTGCTGAAGCAGGATTCCATCTACTATGAACATTTTTACAATGAGCTGCAGCCCTGGAAACACTACATTCCAGTTAAGAGCAACCTGAGCGATCTGCTAGAAAAACTTAAATGGGCGAAAGATCACGATGAAGAGGCCAAAAAGATAGCAAAAGCAGGACAAGAATTTGCAAGAAATAATCTCATGGGCGATGACATATTCTGTTATTATTTCAAACTTTTCCAGGAATATGCCAATTTACAAGTGAGTGAGCCCCAAATCCGAGAGGGCATGAAAAGGGTAGAACCACAGACTGAGGACGACCTCTTCCCTTGTACTTGCCATAGGAAAAAGACCAAAGATGAACTCTGATATGCAAAATAACTTCTATTAGAATAATGGTGCTCTGAAGACTCTTCTTAACTAAAAAGAAGAATTTTTTTAAGTATTAATTCCATGGACAATATAAAATCTGTGTGATTGTTTGCAGTATGAAGACACATTTCTACTTATGCAGTATTCTCATGACTGTACTTTAAAGTACATTTTTAGAATTTTATAATAAAACCACCTTTATTTTAAAGGA

Publications

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