Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ANKRD49P3
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:136857494-136858541  UCSC
Coordinates (T2T) chr5:137380137-137381184  UCSC
Coordinates (hg19) chr5:136193183-136194230  UCSC
Strand +
Parental Sequence NM_017704.3
Parental seq. overlap 976 bp
Parental seq. overlap (%) 50.9%
Genomic Region Intergenic
Retrocopy Summary ANKRD49P3, located on chr5:136857494-136858541, is a retrocopy of the parental gene ANKRD49. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ANKRD49
Full Name ankyrin repeat domain 49
Also known as FGIF|GBIF
Coordinate chr11:94493984-94499578
Strand +
Gene summary Involved in positive regulation of transcription, DNA-templated. Predicted to be located in nucleus. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ANKRD49P1
Bonobo Pan paniscus ANKRD49P1
Gorilla Gorilla gorilla ANKRD49P1
Orangutan Pongo abelii ANKRD49P1
Gibbon Nomascus leucogenys ANKRD49P1
Green monkey Chlorocebus sabaeus ANKRD49P2
Crab-eating macaque Macaca fascicularis ANKRD49P1
Rhesus Macaca mulatta ANKRD49P1
Baboon Papio anubis ANKRD49P1
Golden snub-nosed monkey Rhinopithecus roxellana ANKRD49P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ANKRD49P3
ACCGGAAGTGAGATGCATGTTGGCTATTTTCCCTTCTGTCAGATCTTGATGAATAAAGCAATCATAATTCATCTCTAGAAAGATTATTTATACCCTGGCATTTGAAATGCTTTTTATTTAGAATAGTAGTAAAAATGGAAAAAGAAAAAGGAAATGATGATGGAATACCAGACCAAGGGAATTTCTTGGATTTTTCCGAACACTTTAACCAACTTGAATTTTTGGAAACACATGGACACCTTATTCCTACTGGTGCTCAAAGTCTTTGGGTAGGCAATTCTGAAGAAGACGAAGAGCAAGATGAAAAAAATGAAGAGTGGTATCAATTGCAAGAAAAAACAATGGAAAAAGACCCAAGCAAATTGCTTCTTTGGGCTGCTGAAAAAAATCGGCTTACTACAGTACAGAGACTACTTTCTGAAAAGGCTGCTCATGTGAACACTAGGGATGAAGATGAGTATACCCCTCTTCATCGTGCAGCCTACAGTGGACACGTAGATATTGTCTAGGAGATCATTTCACAGGGGGCAGATGCTCATGCAGTGACTGTGGATGGCTGGACGCCCCTGCACAGTGCTTGCAAGTAGAATAATATGAGTGGTTTCTTTCTTACTGCAGCATGATGCAGATATCAATGCCCAAACAAAAGGCCTCTTGGCCCCCTTGCATCTTGCTGCTGGGAACAGAGACAGCAAGGATACCCTAGAACTCCTCCTGGTGAACTGTTACATCAAGCCAGGGCTGAAAAACAACTTGGAAGAAACTGCATTTGATATTGCCAGGAGGACAAGTGTCTATCACTACCTCTTTGAAATTGTGGAAGGCTGTGCAAATTCTTCACCTCAGTCTTAACAGTTCTGGAAATTTTCTTAAGTTTCTAAGTACCAGTGCCTCCTTTGTGTGAGATGTAAAGTATTCCCATAATCAAAGTTGACATTGAACATCTTACTACAAAAATTCAGTGGTATTCATTATAATGTTCTTCCAAGTGAATTGACTGACTTTGATGTCAAAATGTATTTGAAAGTTGTTTGCATACATATTTAAT
>NM_017704.3
AGGAGACGAACCCGGAAGTGAGATGCAAGGCGGCGATTTTCCCTTCTGTCAGATCTTGATGAACAAAGCAGTCATAATTCATCTCTAGAAAGATTTATATCCTGGCATTTGAAATGCTTTTTATTTAGAATAGTAGTAAAAAATGGAAAAAGAAAAAGGAAATGATGATGGAATACCAGACCAAGAGAATTCCTTGGATTTTTCTGAACACTTTAACCAACTTGAATTGTTGGAAACACATGGACACCTTATTCCTACTGGTACTCAAAGTCTTTGGGTAGGCAATTCTGATGAAGATGAGGAGCAAGATGACAAAAATGAAGAGTGGTATCGATTGCAAGAAAAAAAAATGGAAAAAGACCCAAGCAGATTGCTTCTTTGGGCTGCTGAAAAAAATCGGCTTACCACAGTGCGGAGACTCCTTTCTGAAAAGGCCACTCACGTGAACACTAGGGATGAAGATGAGTATACCCCTCTTCATCGAGCAGCCTACAGTGGACACTTAGATATTGTTCAGGAGCTCATTGCACAGGGGGCCGATGTTCATGCAGTGACTGTGGATGGCTGGACGCCCCTGCACAGTGCTTGTAAGTGGAATAATACCAGAGTGGCTTCTTTCTTACTGCAGCATGATGCAGATATCAATGCCCAAACAAAAGGCCTCTTGACCCCCTTGCATCTTGCTGCTGGGAACAGAGACAGCAAGGATACCCTAGAACTCCTCCTGATGAACCGTTACGTCAAACCAGGGCTGAAAAACAACTTGGAAGAAACTGCATTTGATATTGCCAGGAGGACAAGTATCTATCACTACCTCTTTGAAATTGTGGAAGGCTGTACAAATTCTTCACCTCAGTCTTAACAATTCTAGTAATTTTCCTAAGTTTCTAAATACCAGTGCCTCCTGTGTGTGAGATGTATTCCCATAATCAAAGTTGACGTCAAACATCTTACTACAAAAATTCAGTGACATTCATTATAACATTCTTCCAAGTGAATTGCCTGACTTTGATGTCAAAATGTATTTGAAAGTAATTTGCATATATCTTTAATTATTTCTGTGGAGTTTGTGATTTTTTTATCAGAAATAATTTTAATGTGTGTATACTTAAAAACTTGACACGGGTTGTACAGAAACTGGTATTTTTGGTGCTGATACAAGAGAAATGTATTTTTAAATATCCCACATCCTGGATCTTTGTTGGGTATTTAGTATATTGACATATATTTTTATAAGGTGAGGTAACTCAGAACTTAATTTAAAAGTCTTAAATATTCTGATACAATTCAGCTGTCTTCTCTACCTTACCATAGCCAGTTGCTTTCATTTTAAACCAGAGCAAGTAACATATTAGTGACTTGAATCTTCATAAGTTAAAGTAAAAAACAGCAAAAAACCTAGATCTTTGTCTTTTAGAACACAGACCATTTTCAGGAAAGCAGTTAGCTAAGTGTTTAATTCATGAATATTGTATACTGCATCCCCTACCACAATTTACACAATCCTGTGGATAGTCCTACCTCACCCTGGTCAACCTACATGATCCTTAAGCTAATGGCGAATCACGATGACCTTGTAGACATGCACACAACTATACCTTTGTCCAACAGATCATAATATATCTGCTATCCAACTGGTTTTACCTGCCTAATCCTACTGATTTGGGCACTGCTTGTATAGTCTCTCAAGTTCACAGGAAATGTTGATTTTCTAAGGTCCTCATTTTTACAGAGTATACAGGCAAAGTGACAGGGGAAAAGGAATTAGTCTAAGAGTAAGGGGATGATTATTATATTGaggctaaaaccacaaagtggctcaggctttaaaaaaaaaacactgtggataatgacaaaaagCATAAGTAAAAATATTTGAGAAAAATAAAGTACAAGTTTTGAACAACA

Publications

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