Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name EEF1GP2
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:147922323-147923505  UCSC
Coordinates (T2T) chr5:148458049-148459231  UCSC
Coordinates (hg19) chr5:147301886-147303068  UCSC
Strand +
Parental Sequence NM_001404.5
Parental seq. overlap 1040 bp
Parental seq. overlap (%) 71.4%
Genomic Region Intergenic
Retrocopy Summary EEF1GP2, located on chr5:147922323-147923505, is a retrocopy of the parental gene EEF1G. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name EEF1G
Full Name eukaryotic translation elongation factor 1 gamma
Also known as EF1G|GIG35
Coordinate chr11:62559596-62573891
Strand -
Gene summary This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes EEF1GP5
Bonobo Pan paniscus EEF1GP4
Gorilla Gorilla gorilla EEF1GP5
Orangutan Pongo abelii EEF1GP5
Gibbon Nomascus leucogenys EEF1GP1
Green monkey Chlorocebus sabaeus EEF1GP7
Crab-eating macaque Macaca fascicularis EEF1GP6
Rhesus Macaca mulatta EEF1GP6
Baboon Papio anubis EEF1GP6
Golden snub-nosed monkey Rhinopithecus roxellana EEF1GP4
Marmoset Callithrix jacchus EEF1GP2
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>EEF1GP2
GAATTTCCTTCCCACAAGGTTCTAGCATTTAAGGGTGATGATGGATTCTCTGTGTGGGAGAGCAATGCTATTGCCACCTATGTGAGCAATGAGGAGCTGTGGGGAAGTGCTCCAGAGGCAGCAGCCCAGGCTGTGCAGTGGGTGAACTTTGCTGATGATAGCCAGTACCAGGGTGTTCCCACCTTGGGCAAAATGCACCATGACAAACAGGCCACCCAGGATGCAGGGGAAGAGGTGAGGTGAAGTCTGGGGCTGCTAGATGCTCACTTGAAGATGAAGACTTTTTCTGGTGGGTGAGTGAGTGACATTGGCTGACATCATAGTTATCTGCACCTTGTTGTGACTCTATAAGCAGGTAGGTTCTAGAGCCTTCTTTCTACCAGGCCATTCCCATTATCAACTGCTGGTTCCTCACCTACATTTACCAGCCCCAGTTCCAGGCTGTCTTGGGTGGAAATGAAACTGTGTGAGAACATGGCCCACTTTGATGCTAAAATATTTGCAGAGAGCCAGCCTAAAAAGGACACTCCACGGAAAGAGAAAGGTTCACGGGAAGAGAAGCAGAAGCCCCAGGCTGAGCGGAAGGAGGAGAAAAAGGTGGCCACCCCTGCTCCTTAAGCGGAGATGAAGGAATGTGAGCAGCCCAAGAACACCTTTGAGTTGGATGAATTTAAGCACAAGTACTCCATCGAGGACACACTCTGAGGCAATGACATGTTTTGGAGAGCACTTTGATAAAGACGGCTGGTCCCTGAGGTACTCTGAGTATCGCTTCCCTGAAGAACTCACCAGACCTTCATGAGTTGCAGTCTCATCACTGGAATGTTCCAGCGATTGGACGAGCTGAAGAACATGTCTTTGCTAGTGTCATCCTCTTTAGAGTCAACAATAGCAGCTCCATTTCTTGAGTCTGGGTCTTCCAAGGCCAGGAGCTTGCCTTTCTGCTGAGTCCAGATTGGCAGATGGACTCCGAGTCATATAAAAGGCAGAAACTGGATCCTGGAAGCAAAGAGGCCCAGACACTGGTTGGAGAGTACTTTTCCTGGGAGGGGGTCTTCAAGCATTTGGGCAAAGCCTTCAGTCAGCACAAGATCTCCAAGAGAATATTTTTTTTTACCATTGCCAAGCAGCCTGCACTTGCCCTTCACGAAGATGGGAATCATTAAAGGAAACTGAACATTGA
>NM_001404.5
ACTTTGCGGCAGCGCCGAGAACCCCACCCCCTTTCTTTGCGGAATCACCATGGCGGCTGGGACCCTGTACACGTATCCTGAAAACTGGAGGGCCTTCAAGGCTCTCATCGCTGCTCAGTACAGCGGGGCTCAGGTCCGCGTGCTCTCCGCACCACCCCACTTCCATTTTGGCCAAACCAACCGCACCCCTGAATTTCTCCGCAAATTTCCTGCCGGCAAGGTCCCAGCATTTGAGGGTGATGATGGATTCTGTGTGTTTGAGAGCAACGCCATTGCCTACTATGTGAGCAATGAGGAGCTGCGGGGAAGTACTCCAGAGGCAGCAGCCCAGGTGGTGCAGTGGGTGAGCTTTGCTGATTCCGATATAGTGCCCCCAGCCAGTACCTGGGTGTTCCCCACCTTGGGCATCATGCACCACAACAAACAGGCCACTGAGAATGCAAAGGAGGAAGTGAGGCGAATTCTGGGGCTGCTGGATGCTTACTTGAAGACGAGGACTTTTCTGGTGGGCGAACGAGTGACATTGGCTGACATCACAGTTGTCTGCACCCTGTTGTGGCTCTATAAGCAGGTTCTAGAGCCTTCTTTCCGCCAGGCCTTTCCCAATACCAACCGCTGGTTCCTCACCTGCATTAACCAGCCCCAGTTCCGGGCTGTCTTGGGCGAAGTGAAACTGTGTGAGAAGATGGCCCAGTTTGATGCTAAAAAGTTTGCAGAGACCCAACCTAAAAAGGACACACCACGGAAAGAGAAGGGTTCACGGGAAGAGAAGCAGAAGCCCCAGGCTGAGCGGAAGGAGGAGAAAAAGGCGGCTGCCCCTGCTCCTGAGGAGGAGATGGATGAATGTGAGCAGGCGCTGGCTGCTGAGCCCAAGGCCAAGGACCCCTTCGCTCACCTGCCCAAGAGTACCTTTGTGTTGGATGAATTTAAGCGCAAGTACTCCAATGAGGACACACTCTCTGTGGCACTGCCATATTTCTGGGAGCACTTTGATAAGGACGGCTGGTCCCTGTGGTACTCAGAGTATCGCTTCCCTGAAGAACTCACTCAGACCTTCATGAGCTGCAATCTCATCACTGGAATGTTCCAGCGACTGGACAAGCTGAGGAAGAATGCCTTCGCCAGTGTCATCCTTTTTGGAACCAACAATAGCAGCTCCATTTCTGGAGTCTGGGTCTTCCGAGGCCAGGAGCTTGCCTTTCCGCTGAGTCCAGATTGGCAGGTGGACTACGAGTCATACACATGGCGGAAACTGGATCCTGGCAGCGAGGAGACCCAGACGCTGGTTCGAGAGTACTTTTCCTGGGAGGGGGCCTTCCAGCATGTGGGCAAAGCCTTCAATCAGGGCAAGATCTTCAAGTGAACATCTCTTGCCATCACCTAGCTGCCTGCACCTGCCCTTCAGGGAGATGGGGGTCATTAAAGGAAACTGAACATTGAACCCTT

Publications

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