Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name KIF4B
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:155013791-155018132  UCSC
Coordinates (T2T) chr5:155547682-155552023  UCSC
Coordinates (hg19) chr5:154393351-154397692  UCSC
Strand +
Parental Sequence NM_012310.5
Parental seq. overlap 4092 bp
Parental seq. overlap (%) 93.1%
Genomic Region Intergenic
Retrocopy Summary KIF4B, located on chr5:155013791-155018132, is a retrocopy of the parental gene KIF4A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name KIF4A
Full Name kinesin family member 4A
Also known as KIF4|KIF4G1|MRX100|XLID100
Coordinate chrX:70290104-70420886
Strand +
Gene summary This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, Mar 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes KIF4AP1
Bonobo Pan paniscus KIF4AP1
Gorilla Gorilla gorilla KIF4AP1
Orangutan Pongo abelii KIF4AP1
Gibbon Nomascus leucogenys KIF4AP1
Green monkey Chlorocebus sabaeus KIF4AP1
Crab-eating macaque Macaca fascicularis KIF4AP1
Rhesus Macaca mulatta KIF4AP1
Baboon Papio anubis KIF4AP1
Golden snub-nosed monkey Rhinopithecus roxellana KIF4AP1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>KIF4B
CAGGGCGGCGGGAGACCCCGGGTGAACGGGGAAGGGACATTTAGTTTGAGACGGTGCTGAGATAGGATCATGAAGGAAGAGGTGAAGGGAATTCCTGTAAGAGTGGCACTGCGTTGTCGCCCTCTGGTCCCCAAAGAGATTAGCGAGGGCTGCCAGATGTGCCTTTCCTTCGTGCCCGGGGAGACTCAGGTGGTGGTTGGTACTGATAAATCCTTCACCTACGATTTTGTGTTTGACCCCTGTACTGAGCAGGAAGAAGTCTTCAATAAAGCAGTAGCGCCGCTCATAAAAGGCATATTTAAAGGATATAATGCAACGGTCCTGGCCTATGGGCAGACTGGCTCTGGAAAAACCTATTCAATGGGAGGTGCATACACTGCGGAGCAGGAGAATGAACCAACAGTTGGCATTATTCCTAGGGTAATACAACTGCTCTTCAAAGAAATTGATAAAAAGAGTGACTTTGAATTTACTCTGAAAGTGTCTTACTTAGAGATTTACAATGAAGAAATTTTGGATCTTCTATGCCCATCTCGTGAGAAAGCTCAAATAAATATACGGGAGGATCCTAAGGAAGGCATAAAGATTGTGGGACTCACTGAGAAGACTGTTTTAGTTGCCTTGGATACTGTTTCCTGTTTGGAGCAGGGCAACAACTCTAGGACTGTGGCCTCCACAGCTATGAACTCCCAGTCGTCCCGATCTCATGCCATCTTTACAATCTCCATAGAGCAAAGAAAGAAAAGTGACAAGAATTGCAGCTTTCGCTCCAAGCTGCATCTTGTAGATCTCGCTGGATCAGAAAGACAGAAGAAAACCAAGGCTGAAGGGGATCGTCTAAAAGAGGGTATTAATATTAACCGAGGCCTCCTATGCTTGGGAAATGTAATCAGTGCTCTTGGAGATGACAAAAAGGGTAGCTTTGTGCCCTACAGAGATTCCAAGTTAACTCGACTGCTGCAAGATTCTCTAGGAGGTAACAGCCACACTCTTATGATAGCCTGTGTGAGTCCTGCTGACTCCAATCTAGAGGAAACATTAAGTACCCTTCGCTATGCTGACAGAGCAAGAAAAATCAAGAACAAACCTATTGTTAATATTGATCCCCACACAGCTGAACTTAATCATCTAAAGCAACAGGTACAACAGCTACAAGTCTTGTTGCTACAAGCCCATGGAGGTACCCTGCCTGGATCTATAAATGCAGAACCATCAGAGAATCTACAATCCCTGATGGAGAAGAATCAGTCCCTGGTAGAGGAGAATGAAAAATTAAGTCGTTGTCTGAGCAAGGCAGCTGGTCAGACAGCCCAGATGTTGGAGAGGATCATTTTGACAGAGCAAGTGAATGAAAAACTGAACGCCAAGCTAGAAGAGCTCAGGCAGCATGTGGCCTGCAAGCTGGATCTTCAAAAGCTAGTGGAGACTTTGGAAGACCAGGAATTGAAAGAAAATGTAGAGATAATTTGTAACCTGCAGCAACTGATTACCCAGTTATCAGATGAAACTGTTGCTTGCACGGCTGCAGCCATTGATACTGCGGTAGAAGAAGAAGCTCAAGTGGAAACCAGTCCAGAGACAAGCAGGTCTTCTGACGCTTTTACCACTCAGCATGCTCTCCATCAAGCTCAGATGTCTAAGGAGGTGGTTGAGTTGAATAACGCCCTTGCACTGAAAGAGGCCCTAGTTAGGAAGATGACTCAGAACGACAACCAACTACAGCCCATTCAGTTTCAATACCAGGATAACATAAAAAATCTAGAATTAGAAGTCATCAATCTGCAAAAGGAAAAGGAAGAATTGGTTCGTGAACTTCAGACAGCAAAGAAGAATGTCAACCAAGCCAAGCTGAGTGAGCACCGCCACAAACTTCTCCAGGAGCTGGAGGGTCAAATAGCTGATCTGAAGAAGAAACTGAATGAGCAGTCCAAACTTCTGAAACTAAAGGAATCCACAGAGCGTACTGTCTCCAAGCTGAACCAAGAGATATGGATGATGAAAAACCAGCGGGTACAGTTAATGCGTCAAATGAAAGAGGATGCTGAGAAGTTTAGACAATGGAAGCAGAAAAAAGACAAAGAAGTAATACAGTTGAAAGAACGAGACCGTAAGAGGCAATATGAGCTGCTCAAACTTGAAAGAAACTTCCAGAAACAATCCAGTGTGCTCAGACGTAAAACGGAAGAGGCAGCAGCTGCCAACAAGCGACTCAAGGATGCTCTCCAGAAACAACGAGAGGTCACAGATAAGCGGAAAGAGACTCAGAGCCATGGAAAGGAAGGTATTGCAGCTCGAGTGAGGAATTGGCTTGGAAATGAAATTGAGGTTATGGTCAGTACTGAGGAAGCCAAACGCCATCTGAATGACCTCCTTGAAGACAGAAAGATCCTGGCTCAGGATGTGGTTCAACTCAAAGAAAAAAAGGAATCTCGGGAGAATCCACCTCCTAAACTCCGGAAGTGTACATTCTCCCTTTCTGAGGTGCATGGTCAAGTTTTGGAGTCAGAAGATTGTATTACAAAACAGATTGAAAGCCTAGAGACTGAAATGGAACTCAGGAGTGCTCAGATTGCTGACCTACAGCAGAAGCTGCTGGATGCAGAAAGTGAAGATAGGCCAAAACAATGCTGGGAGAATATTGCCACCATTCTGGAAGCCAAGTGTGCCCTGAAATATTTGATTGGAGAGCTGGTCTCCTCCAAAATACATGTCACCAAACTTGAAAACAGCCTGAGACAGAGCAAGGCCAGCTGTGCTGACATGCAGAAGATGCTATTTGAGGAACAAAATCATTTTTCTGAGATAGAGACAGAGTTACAAGCTGAGCTGGTCAGAATGGAGCAACAGCACCAAGAGAAGGTGCTATACCTTGTCAGCCAGCTGCAGGAAAGCCAAATGGCAGAGAAGCAGTTAGAGAAATCAGCCAGTGAAAAGGAACAACAGCTGGTGAGCACACTGCAGTGTCAGGATGAAGAACTTGAGAAGATGCGAGAAGTGTGTGAGCAAAATCAGCAGCTTCTCCAAGAGAATGAAATCATCAAGCAGAAACTGATCCTCCTCCAGGTAGCCAGCAGACAGAAACATCTTCCTAATGATACCCTTCTATCTCCAGACTCTTCTTTTGAATATATCCCACCTAAGCCAAAACCTTCTCGTGTTAAAGAAAAGTTTCTGGAGCAAAGCATGGACATCGAGGATCTAAAATATTGTTCAGAGCATTCTGTGAaATGGAAGCCAACAAAATTAGTCAAGGTGTCCAGGAAGAACATCCAAGGGTGTTCCTGCAAGGGCTGGTGTGGGAACAAGCAGTGTGGGTGCAGGAAGCAAAAGTCAGACTGTGGTGTGGACTGTAGCTGTGACCCCACAAAGTGTCGGAACCGCCAGCAAGGCAAGGATAGCTTGGGCACTGTTGAACAGACCCAGGATTCCGAAGGCTCCTTCAAACTGGAGGATCCTACCGAGGTGACCCCAGGATTGAGCTTCTTTAACCCTGTCTGTGCCACCCCCAATAGCAAGATCCTGAAAGAGATGTGTGACATGGAGCAGGTGCTGTCAAAGAAGACTGCTCCAGCTCCCTCCCCTTTTGACCTCCCAGAGTCGAAACATGGAGCAACAGAATACCAACAAAATAAGCCTCCAGGGAAGAAAAAGAAACGAGCTCTGGCTAGCAACACCAGCTTCTTCTCTGGCTGCTCCCCTATCGAAGAAGAGGCCCACTGAAGTTGGAGTCATCATCTCTACCCCCAATCTGGCTTGGGAGATGCTTTCCAGTTGCAGCCAGAAGGGGTTTTTTAAATGACTTCTCTGGATTTCAGGTTTCTTGCCGTTGAAAAAAAGGAACAAAGCATTACTAAAAAGAAGGTAACCTTTGTTGGATGTTGTCCCTCAGTCTCCATCCCCAGACTACTGCTCTCTGCTCTCTAGAAGGCTGCTAAACCACCTGCTGAAGAGAGAACCAACAGACTTTCCTAATGACTCATCAGGAACCAGTCCTCAGTATGATCAAGTTCCTTCTTATTTGTGAGCAGTTCAGGCTATCTCCTGATGGGGATGAGGCCAAGGCTTTCTTATCTTTTGGTTGTCTCTGCTTAATGGAGGAGCCTGGCCTAGGATGGAGGTCTGGCTCAGATCTTTCACTCCACCTCGGGAATGGGGTTGTGATCTTTCCTGTCCTGACCCCCTCTGAATTGTAAGTGTTTCAATAGTACTCTTGATTGTATGCCATGTTGTTGAAGTAAATGAATTATTTTTAAATGTTAAGTAAATAAACCTTAGCCCATCTACTGTT
>NM_012310.5
AGGGCGGCGGGAGGCCCAGGGAGAACGGGGAAGGGACATTTAGTTTGAGACGGTGCTGAGATAGGATCATGAAGGAAGAGGTGAAGGGAATTCCCGTAAGAGTGGCGCTGCGTTGTCGCCCTCTGGTCCCCAAAGAGATTAGCGAGGGCTGCCAGATGTGCCTTTCCTTCGTGCCCGGAGAGCCTCAGGTGGTGGTTGGTACAGATAAATCCTTCACCTACGATTTTGTATTTGATCCCTCTACTGAACAGGAAGAAGTCTTCAATACAGCAGTAGCGCCACTCATAAAAGGTGTATTTAAAGGATATAATGCAACGGTCCTGGCCTATGGGCAGACTGGCTCTGGAAAAACCTATTCAATGGGAGGTGCATATACTGCAGAGCAAGAGAATGAACCAACAGTTGGGGTTATTCCTAGGGTAATACAACTGCTCTTCAAAGAAATTGATAAAAAGAGTGACTTTGAATTTACTCTGAAAGTGTCTTACTTAGAGATTTACAATGAAGAAATTTTGGATCTTCTATGCCCATCTCGTGAGAAAGCTCAAATAAATATACGAGAGGATCCTAAGGAAGGCATAAAGATTGTGGGACTCACTGAGAAGACTGTTTTGGTTGCCTTGGATACTGTTTCCTGTTTGGAACAGGGCAACAACTCTAGGACTGTGGCCTCCACGGCTATGAACTCCCAGTCGTCCCGATCTCATGCCATCTTTACAATCTCCTTAGAGCAAAGAAAGAAAAGTGACAAGAATAGCAGCTTTCGCTCCAAGCTGCATCTTGTAGACCTCGCTGGATCAGAAAGACAGAAGAAAACCAAGGCTGAAGGGGATCGTCTAAAAGAGGGTATTAATATTAACCGAGGCCTCCTATGCTTGGGAAATGTAATCAGTGCTCTTGGAGATGACAAAAAGGGTGGCTTTGTGCCCTACAGAGATTCCAAGTTGACTCGACTGCTTCAAGATTCTCTAGGAGGTAATAGCCATACTCTTATGATAGCCTGTGTGAGTCCTGCTGACTCCAATCTAGAGGAAACATTAAATACCCTTCGCTATGCTGACAGAGCAAGAAAAATCAAGAACAAACCTATTGTTAATATTGATCCCCAGACAGCTGAACTTAATCATCTAAAGCAACAGGTACAACAGCTACAAGTCTTGTTGCTACAGGCCCATGGAGGTACCCTGCCTGGATCTATAACTGTGGAACCATCAGAGAATCTACAATCCCTGATGGAGAAGAATCAGTCCCTGGTAGAGGAGAATGAAAAATTAAGTCGTGGTCTGAGCGAGGCAGCTGGTCAGACAGCCCAGATGTTGGAGAGGATCATTTTGACAGAGCAAGCGAATGAAAAAATGAACGCCAAGCTAGAAGAGCTCAGGCAGCATGCGGCCTGCAAACTGGATCTTCAAAAGCTAGTGGAGACTTTGGAAGACCAGGAATTGAAAGAAAATGTAGAGATAATTTGTAACCTGCAGCAATTGATTACCCAGTTATCGGATGAAACTGTTGCTTGCATGGCTGCAGCCATTGATACTGCGGTGGAGCAAGAAGCCCAAGTAGAAACCAGTCCAGAGACGAGCAGGTCTTCTGACGCTTTTACCACTCAGCATGCTCTCCGTCAAGCGCAGATGTCTAAGGAGCTGGTTGAGTTGAATAAAGCGCTTGCACTGAAAGAGGCCCTGGCTAGGAAGATGACTCAGAATGACAGCCAACTGCAGCCCATTCAGTACCAATACCAGGATAACATAAAAGAGCTAGAATTAGAAGTCATCAATCTGCAAAAGGAAAAGGAAGAATTGGTTCTTGAACTTCAGACAGCAAAGAAGGATGCCAACCAAGCCAAGTTGAGTGAGCGCCGCCGCAAACGTCTCCAGGAGCTGGAGGGTCAAATTGCTGATCTGAAGAAGAAACTGAATGAGCAGTCCAAACTTCTGAAACTAAAGGAATCCACAGAGCGTACTGTCTCCAAACTGAACCAGGAGATACGGATGATGAAAAACCAGCGGGTACAGTTAATGCGTCAAATGAAAGAAGATGCTGAGAAGTTTAGACAGTGGAAGCAGAAAAAAGACAAAGAAGTAATACAGTTAAAAGAACGAGACCGTAAGAGGCAATATGAGCTGCTGAAACTTGAAAGAAACTTCCAGAAACAATCCAATGTGCTCAGACGTAAAACGGAGGAGgcagcagctgccaacaagcgtctcaaggaTGCTCTCCAGAAACAACGGGAGGTTGCAGATAAGCGGAAAGAGACTCAGAGCCGTGGAATGGAAGGCACTGCAGCTCGAGTGAAGAATTGGCTTGGAAACGAAATTGAGGTTATGGTCAGTACTGAGGAAGCCAAACGCCATCTGAATGACCTCCTTGAAGATAGAAAGATCCTGGCTCAAGATGTGGCTCAACTCAAAGAAAAAAAGGAATCTGGGGAGAATCCACCTCCTAAACTCCGGAGGCGTACATTCTCCCTTACTGAAGTGCGTGGTCAAGTTTCGGAGTCAGAAGATTCTATTACAAAGCAGATTGAAAGCCTAGAGACTGAAATGGAATTCAGGAGTGCTCAGATTGCTGACCTACAGCAGAAGCTGCTGGATGCAGAAAGTGAAGACAGACCAAAACAACGCTGGGAGAATATTGCCACCATTCTGGAAGCCAAGTGTGCCCTGAAATATTTGATTGGAGAGCTGGTCTCCTCCAAAATACAGGTCAGCAAACTTGAAAGCAGCCTGAAACAGAGCAAGACCAGCTGTGCTGACATGCAGAAGATGCTGTTTGAGGAACGAAATCATTTTGCCGAGATAGAGACAGAGTTACAAGCTGAGCTGGTCAGAATGGAGCAACAGCACCAAGAGAAGGTGCTGTACCTTCTCAGCCAGCTGCAGCAAAGCCAAATGGCAGAGAAGCAGTTAGAGGAATCAGTCAGTGAAAAGGAACAGCAGCTGCTGAGCACACTGAAGTGTCAGGATGAAGAACTTGAGAAAATGCGAGAAGTGTGTGAGCAAAATCAGCAGCTTCTCCGAGAGAATGAAATCATCAAGCAGAAACTGACCCTCCTCCAGGTAGCCAGCAGACAGAAACATCTTCCTAAGGATACCCTTCTATCTCCAGACTCTTCTTTTGAATATGTCCCACCTAAGCCAAAACCTTCTCGTGTTAAAGAAAAGTTCCTGGAGCAAAGCATGGACATCGAGGATCTAAAATATTGTTCAGAGCATTCTGTGAatgagcatgaggatggtgatggtgatgatgatgagggggatgacgaggaATGGAAGCCAACAAAATTAGTTAAGGTGTCCAGGAAGAACATCCAAGGGTGTTCCTGCAAGGGCTGGTGTGGAAACAAGCAGTGTGGGTGCAGGAAGCAAAAGTCAGACTGTGGTGTGGACTGTTGCTGTGACCCCACAAAGTGTCGGAACCGCCAGCAAGGCAAGGATAGCTTGGGCACTGTTGAACGGACCCAGGATTCCGAAGGCTCCTTCAAACTGGAGGATCCTACCGAGGTGACCCCAGGATTGAGCTTCTTTAATCCCGTCTGTGCCACCCCCAATAGCAAGATCCTGAAAGAGATGTGCGATGTGGAGCAGGTGCTGTCAAAGAAGACTCCCCCAGCTCCCTCCCCTTTTGACCTCCCAGAGTTGAAACATGTAGCAACAGAATACCAAGAAAACAAGGCTCCAGGGAAGAAAAAGAAACGGGCTCTGGCCAGCAACACCAGCTTCTTCTCTGGCTGCTCCCCTATCGAAGAAGAGGCCCACTGAAGTTGGAGTCATCATCTCTACCCCCAGTCTGGCTTGGGAGATGCTTTCAGGTTGCAGCCAGAAGGGGTTTTTTAAATGACTTCTCTGGATTTCAGGTTTCTTGCTGTTGAAAAAAGGAACAAAGCGTTACTGAAAAGAAGGTAACCTTTGTTGGATGTGGGCCTTAGCCTCCAGGTCCAGACTACTACTCTATGTTCTCCAGAAGGGTGCTAAGTCACCTACTGAAGAGAGAACCAACTGACTTTCCTATTGACTCATCAGGAACCAGTCCTCAGTCTGGTCAAGTTGTTTCTTATTTGTGAGCAGTTCAGGCTATCTCCTGATGGGGATGAGGCCAAGGCTTTCTTATCTTTTGGTTGTCTCTGCTTAATGGAGGAGCCTGGCCTAGGATGGAGGCCTGGCTTAGATCTTTCATTCCACCTCAGGAATGAGGTTGTGATCTTTCCTGTCCTGACCCTCTCTGAATTATGTTTCAATAGTACTCTTGATTGTCTGCCATGTTGTTGAAGCAAATGAATTATTTTTAAATGTTAAGTAAGTAAATAAACCTTAGCCCGTCTACTGTTTGGGAAGATCCTTCTGTGCTAGAGGGAGAAATAAAATTTCAACCTGTGTTCCTCA

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