Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PPIGP1
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:155491160-155493821  UCSC
Coordinates (T2T) chr5:156025026-156027687  UCSC
Coordinates (hg19) chr5:154870720-154873381  UCSC
Strand +
Parental Sequence XM_005246967.1
Parental seq. overlap 2346 bp
Parental seq. overlap (%) 36.7%
Genomic Region Intergenic
Retrocopy Summary PPIGP1, located on chr5:155491160-155493821, is a retrocopy of the parental gene PPIG. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PPIG
Full Name peptidylprolyl isomerase G
Also known as CARS-Cyp|CYP|SCAF10|SRCyp
Coordinate chr2:169584343-169641406
Strand +
Gene summary Enables cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in protein peptidyl-prolyl isomerization. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PPIGP1
Bonobo Pan paniscus PPIGP1
Gorilla Gorilla gorilla PPIGP1
Orangutan Pongo abelii PPIGP1
Gibbon Nomascus leucogenys PPIGP1
Green monkey Chlorocebus sabaeus PPIGP1
Crab-eating macaque Macaca fascicularis PPIGP1
Rhesus Macaca mulatta PPIGP1
Baboon Papio anubis PPIGP1
Golden snub-nosed monkey Rhinopithecus roxellana PPIGP1
Marmoset Callithrix jacchus PPIGP1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PPIGP1
AGGAGGGAGGCAGTTAGCGGGCTTTAGCTCCTTTTCTGGAGGGGGTAGATATGAAGCGGTTTAAAGGATTGGACCAAAAGAAGAGGAAACTCTACCAGTGCAAGAGCCAAGGGATCAGTTGTCCTTGTTTTTTTTTTTTTGGTCTTGCCTTCATTTGAAGATTAAGTATTGGAGCCATGGGAATAAAGATTCAATGTCCTCGATTTTTTTTTTTTTGACATTGCCATTAACAACCTGCTGGAAGAGTTGTCTTTGAATTATTTTCTGATGTGTGCCCCAAAACACGTGAGAAGTTTAGTTGTCTTTGTACAGGTGAAAGGGGGACAGGGAAATCAACTCAGAGCCATTACATTGTAAGAGTTGTCTCTTTCAGAGTTGTCAAGGATTTTATGGTTTAAGGTGCTGACTTCAGTGAAGGAAATGGACGAGGAGGGGAATCTATCTAAGAAGAATTTTTTGAAGATGAGAATTTTGCTGTTAAAAACAACAAAGAATTTCTCTTGTCAATGGCCAACAGAAGGAAGGATACAAATGGTTTACAGTTCTTCATAACAATGAAACCAACTCTTCATTTAGATGGGCATCATGTTGTTTTTGGGCAAGTAATCTCTAGCCAAGAAGTTGTGAGAGAGATAGAAAACCACAAGATGGATGCCGCTAGCAAAGCATTTACAGAGGTACAGATACTCAGTTGTGGAGAGCTGATTCCCAAATCTAAAGTTAAGAAAGAAGAAAAGAAAATGTATAATAGTGACTAAGATAGCTCAAATGATTCTCAGTTCTCACCTGATTCCTGTGATTCCGAAAATGCTTCTGAAGAGAAATCAAAGAAAAGAGGAAAAAACTTAGGAAAAATTCCCAAAAACACAAGAAGGAAAAGAAGAAGTGAAAGAAAAGCAAGAAGAGTGAATCTAGTAAGAGTGAAGCTGAAAATCTTAGAGCACAACCCCAGTCTACTGTCCATCCAGAAAAGATCCCTCCTATACCTGAAAATAGATTTCCTGATGAGAAAAAGTCCTCCTATAGCTGATGCAATGATGTAATCTATCTAACTCCCAGCCTGCTTCATACCAGAGACGACTTTTAGTTACTAGATCTGGCAGGAGAATTAAAGGAAGAGGATCAAGGTGCTATCAAACTCCTTCCAGATCCAGATCAAGGGATTGTTTCAGACTTAGTGAGACTCCTGCACATTGGAGGCAAGAGATGCCGAGAGCTCAAAGGATGAGGGTATCAAGTGGTGAAAGATGGATCAAAGGGGATAAGAGTGAGTTGAATGAAATAAAAGAAAATCAGAGAAGTCTAGTTAGAGTAAAAGAGAGAAAAATAACTAACCACAGGAATGTATCTGAGAGTCCAAACAGAAAAAATGAAAAGGAAAAGAAAGTTAAAGACTGTAAATCTAACAGCAAAGAGAGACATCTGAAGAAATTCAAAAAAAGATGATAAATACAATACGAACAAAGTGAAGAAAAGGGCCAAATCTAAAATTAAGAGTAAGAGCAAAAAGAAATCAAAGAGTAAAGAAGGAGATTCAAGACATAATAGACATGAAGAAAAGAGGATGAGGTCAAGGAGCAAAGGAAGGGATCATGAGAATGTTAAAGAAAAAGAAAAGGAGCTTGATTCAAAAGGAAACGATCAGGAAAGGGGTAGAAGTAAAGAGAAGTCTAAACAGTTAGAATCAAAGAGTAATGAGCATGATCATAGTAAAACTAAGGAAAAGGATAGATGTGCACAATCCAGGAGTAGAGAATGTGATATAACTGAAGGTAAACACAGTTATAATAGTGTGATCAAGAAGCCATGACAGAGATTGCAGCAGAAGCAAGGAGCACCATAGATACAGAGGAAAGGAATACAGGAGGAGAGGACAGTCACAAAGCCGAGGGAGAAGAACACCACCAGGAAGATCAAGAAGTAGAGATAGGGGTAGAAGGAGGAGAGACTCACGGAGCTCAGAGACAGAAGAAAGTAAAAACAGAAACAAAGAAAAACACAGAAACCAAGAAAGTAAGAGTTCACACAGAAAGAAAATTCTGAGAGTGAGAAAAGAATGTACTGTAAAAGTCATGATCATAATAGCTCAAATAATAGCAGGGGAAAAAAAGGCTGATATAGATAAAAGTCTCTTCTCAAAAATAAAACAAAGCAGTCAGAACAATGAATTAAAGTCCTCCACATTGAAAAATAAGGAGGATGAGAAGATCAGATCCTCAGTGGAAAAAGAAAACCAAGAATCAAAGGGTCAAGAAAGTGACCATGTACGTGAAAGAAAAAAAATTTGATTATGAATCAAGCCCTGAAACATATGAAGACAAAAGTGGATGAGTGAGTTATATAAACTTATTTCCGTTCTGTTTTGAATTTTAAGTTTGAGAGACTTGCTAGTGAATCTTCTTTATGTTGTTTTCCTTTTCATTGTTTTTGGGTTGTTTTATGCTTGCCCCTTTTTTTAAAATGTGGATTTCATTGAGTTGATCTTTTGATAATCTGCAATCTGGATAACTCGTGCTGCTAAAGTTTTAATAAACTTGAAATGCGAA
>XM_005246967.1
CTTCCGGTGCGACGCTGTCTCTCCATGCCAGGACTGAGTTGTGGGGGAGGGAGGCGGTTAGCGGGCTTTAGCGCCTTTTCTGGCGGCGGTAGATTTGAAGCGCTTCAAAGGACCGGACCCAGAGAAGAGGAAAACTCTACCGGTGCAGGTAAGTGGAGCACAGGGATCAGTTGTCCTTGTTTTTTTTTGGTCTTTTCTTCATTTGAAGATTAAGTATTGGAGCCATGGGAATAAAGGTTCAACGTCCTCGATGTTTTTTTGACATTGCCATTAACAATCAACCTGCTGGAAGAGTTGTCTTTGAATTATTTTCTGATGTGTGCCCCAAAACATGCGAGAACTTTCGTTGTCTTTGTACAGGTGAAAAGGGGACCGGGAAATCAACTCAGAAACCATTACATTATAAGAGTTGTCTCTTTCACAGAGTTGTCAAGGATTTTATGGTTCAAGGTGGTGACTTCAGTGAAGGAAATGGACGAGGAGGGGAATCTATCTATGGAGGATTTTTTGAAGACGAGAGTTTCGCTGTTAAACACAACAAAGAATTTCTCTTGTCAATGGCCAACAGAGGGAAGGATACAAATGGTTCACAGTTCTTCATAACAACGAAACCAACTCCTCATTTAGATGGGCATCATGTTGTTTTTGGACAAGTAATCTCTGGTCAAGAAGTTGTAAGAGAGATTGAAAACCAGAAAACAGATGCAGCTAGCAAACCGTTTGCGGAGGTACGGATACTCAGTTGTGGAGAGCTGATTCCCAAATCTAAAGTTAAGAAAGAAGAAAAGAAAAGGCATAAatcatcatcatcttcctcctcctcatcTAGTGACTCAGATAGCTCAAGTGATTCTCAGTCCTCTTCTGATTCCTCTGATTCCGAAAGTGCTACTGAAGAGAAATCAAAGAAAAGAAAAAAGAAACATCGGAAAAATTCCCGAAAACACAAGAAAGAAAAGAAAAAGCGAAAGAAAAGCAAGAAGAGTGCATCTAGTGAGAGTGAAGCTGAAAATCTTGAAGCACAACCCCAGTCTACTGTCCGTCCAGAAGAGATCCCTCCTATACCTGAAAATAGATTCCTAATGAGAAAAAGTCCTCCTAAAGCTGATgagaaggaaaggaaaaacagagagagagaaagggaaagagagTGTAATCCACCTAACTCCCAGCCTGCTTCATACCAGAGACGACTTTTAGTTACTAGATCTGGCAGGAAAATTAAAGGAAGAGGACCAAGGCGTTATCGAACTCCTTCCAGATCCAGATCAAGGGATCGTTTCAGACGTAGTGAGACTCCTCCACATTGGAGGCAAGAGATGCAGAGAGCTCAAAGAATGAGGGTATCAAGTGGTGAAAGATGGATCAAGGGGGATAAGAGTGAGTTGAATGAAATAAAAGAAAATCAGAGAAGTCCAGTTAGAGTAAAAGAGAGAAAAATAACAGATCACAGGAATGTATCTGAGAGTCCAAACAGAAAAAATGAAAAGGAGAAGAAAGTTAAAGACCATAAATCTAACAGCAAAGAGAGAGACATCAGAAGAAATTCAGAAAAAGATGACAAGTATAAAAACAAAGTGAAGAAAAGGGCCAAATCTAAAAGTAGGAGTAAGAGCAAAGAGAAATCAAAGAGTAAAGAAAGAGATTCAAAACATAATAGAAATGAAGAAAAGAGGATGAGGTCAAGGAGTAAAGGAAGGGATCATGAAAATGTTAAAGAAAAAGAAAAGCAGTCTGATTCTAAAGGAAAAGATCAGGAAAGGAGTAGAAGTAAAGAGAAGTCTAAACAGTTAGAATCAAAGAGTAATGAGCATGATCACAGTAAAAGTAAGGAAAAGGATAGACGCGCACAATCCAGGAGTAGAGAATGTGATATAACTAAAGGTAAACACAGTTATAATagcagaacaagagaacgaagcagaagtagggacagaagcagaagAGTGCGATCAAGAACCCATGACAGAGATCGCAGCAGAAGCAAGGAGTACCATAGATACAGAGAACAGGAATACAGGAGAAGAGGACGGTCACGAAGCCGAGAGAGAAGAACACCACCAGGAAGATCAAGAAGTAAAGATAGGAGGAGAAGGAGGAGAGACTCACGGAGCTCAGAGAGAGAAGaaagtcaaagcagaaacaaagacaaatacagaaaccaagaGAGTAAGAGCTCACACAGAAAAGAAAATTCTGAGAGTGAGAAAAGAATGTACTCTAAAAGTCGTGATCATAATAGCTCAAATAACAGCAGGGAAAAAAAGGCTGATAGAGATCAAAGTCCCTTCTCAAAAATAAAACAAAGCAGTCAGGACAATGAATTAAAGTCCTCCATGTTGAAAAATAAGGAGGATGAGAAGATCAGATCCTCAGTGGAAAAAGAAAACCAAAAATCAAAAGGTCAAGAAAATGACCATGTACATGAAAAAAATAAAAAATTTGATCATGAATCAAGCCCTGGAACAGATGAAGACAAAAGCGGATGAGTGAGTTATATAAACTTACTTCCATTCTGTTTCGGATTTTAAGTTTGAGAGACTTGCTAATGAATCTCCTTTATGTTGTTTTCCTTTTCATTGTTTTTGGATTGTTTTATGTTTGTCCTTTTTTTTCTTAATGTGGATTTCATTGAGTTGATTTTTTGATAATCTGCAATCTGGATAATTTGTACTGCTAAAGTTTTAATAAACTCGACATGAGAAAAACACTTTGGTGTAGTACTGTGTGCTGTGTTTAACTATTTTATGTATGCATTACTGTGTTGCAACAATTAGCCAATAGCATCCTAATTTGTTTAGTCAGCCATTTGGAATGGTTGCAATGCATTGTTGCAAAAGCTTGTGTTTCTCATGATTAAAGTAACTTTAGAAGCCACTAGAAGACATCTTGTATAGATTTTCTGATTGCGTTATAAATAGAGGTTTGCAGCGGTTTCTTTTAATTACACAGAAGCAGGGTCCTAATAACCTGAGATCTTAAATCATCACTTTTGATTTTATAGTAATTTGTGCTTTAAAATAGATGTATTTATATTGCACTTCATACTCTATTCTTTATAGTTCGAGCCATAGCTTGTTTCCTATTAATGCTTTTCCTGTCTAGTTGTGTTTTACTTAACTGCCTATAAAAATCGTAAGAGTAATTTTTTTCAGTTGATGTACTGATTGAGCTTGAGTTGCTGTTATACAGCATTTGACAGGAACTATACCTTGGAAAATCAGATTGTGATTCTCAGTTCTGTGTTGCTTTTGGTTTGAAGAGTTTTGGGAACGTTTTAATTATTAATTACCCTTCTCTAAACTTTAAAAAAAAAAAAGCTTTTCTCATTAAAACATACCATTTGTGCAGGTCCTTAAGCTATACAGATTCTAAAAATTGTTAGTATTGAGACATTAACTTCTAAGATTTCTCTTTTTTGGCCTCCAACCTATATAGAATTGAGTGTTAACTCTGCATGGATTTTGTTTGTTTTAATTGAACTGACTTCTCTAACTCTCATAGCTGTGAGTTCCAAATGGCAAGAAAATGCATCTTTTCTATATATGTATCACGATAGGCTATAGCATGTTTATGACTCTGGTTTCTTTCTCTTCAGGTGGTTTTATACCATTACTGTTAATGTTATTTTAACTTGGCATGTATAACATTGCCATATAGAGTAGAGTAGAAAGTTGCAAATTTTGATAGTTTACAGAGTTAAACACTAAACATATCCAAAGTCCATTTAGAGTTTTGGGTGTTGTATTTTGCCATTTTTGTGATGTGTGGCCTTTTATTCTGTAATCTCTTCTAAATAAAACATTGAACATCCAGCAAACATAAAACCTGCCTCATTTGAAAAGGAATTTCAAAATTCCAATTAATAGGATTCTCTAGAGAGTTTTGTACTTTAATATTTGTCAGTGTAGTGTCAACTCTGTTACCAAGGTAGCTTCTTGGTAAATCCAGTAGCTACTCAATGCTATTTGTACTGAATAAAGCAATTATTAACATGATACTTCCCACTATTGATTAATGCAATATTGATATATTTGGCGTTGTGGTAGCTGTTGCAGAATGAATAGTGTAATGACCATAAGATTGCTTGGAAAATTGTAATACAGATATCCACAATGAATTCTTTCCAAAATTTTTTTTTCCGATGATAAAAGTAGTAGATGTTTATTATAAAATCCAAGGTGATTGATTCCTTAGAGACTGACCACAAACCCACATTAGGGATAATTGAGTCTGAGTGCCCAAGCTATATAACGTTATGTAGTTTAAGCAAGTTATTGTTTGTCTTAATTTCAGTTAACTGCATTTTAAAATTGTTGTTATAAACTATTTGAGCTTTAAGAAAGGTGCTATTTAAGAAAGGATTTCTAATAACAGTTAAATATTTTTTTTAAGTCCATGCTAAGTAAAAATTCTTACATGTTGTCTGATCCCAGAGCTTTATCTACTAAAAATTATACATAAGGATTTCCAAATCTTAGAGTTTCAAAAAGTAACCATAGGGAAAAAAATTGTAGTAATTTCTATAGGCAATATTCTGTTTGGGTTATCAAAAGAGCAACTCCATGCTCCGCATTATTTATAGTCCTTATTTTAAAGTTTTATTAGCTCTCTTTACAGAACAGATGTGAAGGAGTTGAGAGGACAATCAACTAGATTTTATTTTTAGAATATAAAGAACATTTTTAAAATGATTAAACAGCATTAACTGTACCTCAGGATCTGCGCATGCATCTGAATAGCACACGGCTCAAATGGTCCTTTCCTTTTGTTACATTTAGTAGTTGTGCCATCTTTAGTTTTTGCTTTGAACATTGTTTTCCTAAAAGTCAACTATTACTTTCCCATCAAGTTGGTTTTATAGTTATGTCTAAATTTATGGTTCATGTCAAAGTATTTTTGACTTAATATCCTTTTAAAAATATTTAAACTGATTTATTGCTCAATTGGTGATAGCTGAGAAAATTTTTTCAATATGTAGAATTTTCATGGTTATTTTGTATGAATTATTTTTCTGGGTAAGCCATCTGCCACAGAAATTGACACTATGGTGAGATTAATGTTAATGAAATGAGCAGTAGAGAAGCTACTGGATTGCTTTAAAACATTCTTTGATTAAATTACTACATAGTTGGTAAGTTCATAGTTTTAAGTTACTTAATTGAAGCCCTCAGAAGTTGCAAAGAATTTATCTGATAAATCTGCCTTTGCACAAATGTGATACTGATGCATGGACGGCTTTGCGGAATGACCTTTGATATTTGTGCCTAGTGGAAGGTATGGAGCTAAACAATTAAAGAACTCTTCATTATGGATAGGCACATATTGGATCTCTGGTATTTTGGGTAGTGGTATTAACTTGACAATTCTAATTTATTttagttagtatatgtagcaagttagtatgtttgttagtagttTATTGTACTTCATTCCAGTTGGTAATATAGTTTTCATCACACTAAACTTTTTATACTAAATTTCTGTAGAAGCTTGTTGGGTTTGCCTTCACCAGAAGGTACTTTAAATACCTACCATAGCTGATTTGTTATAAAGAAACAAAATGGGTGTTCTTCTGTTTCCTTTTGATTATGTTTACTGTAATTATTTCATTTTGGATTTATACATTTACAATTGAATAAGGATTATAGGTTGATAAGCTGTTTATTGTGAAAAGATGTGTTTTGTTACAAATACTTGTTTTAAAAATTAATAAGCCCCCAGGAAGTACAGCATTGACTGGCACAACTGCCCATAGTGAGCTTCCCAACTAACTGCCTTCAGTGGATTCGGGCAAGTGCAAAGTCTTTGGCCTATTGTGTGACAAAGAGGTATATATTaaaggaaaagaaaaatgacatgaataagaaaaTTCCGTCAACAAGGTTGGAGTAGGGAGTTGTTGAGGGGTTTAGTTTGTTTTAAAAGGTATGTGAGGGAGTGGTGGGGTGGATTTGTGTTTCTGACTTTTTTTCTTTAAGCAAATTCCATATGTTACCAAAAGCACATGCTGTATATTTTCTTCCCCTTTTGTGTGTATATAGTATTTTGAAAGATAAATGAATTGGGTATTTGTATGTGGGATGTACAAAATTGTGGCCGCTCTCTTTGTGGAAGGAAAAAACATAAATGAAGTTAATGCACTTCTTTTCCTAGCCCAAAAGTCACTGTGATTATATTTTTTTAATGAAGTTTAGAAAAAAAGCTGTTGTCTTCTCAATTGTAAAATTAGTTTCAAAATGCTGCTTCTCTTATCATTAGTCTAGTAATTGTTGAACTTTTCTGCAAACTGCATTTTACAAAATTGAAACTTGGAAGCTGTATTAACTTTTATAGTTAAACATTGTATTAAATAAACTATACTATAATAAA

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