Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name CCNQP4
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:172762076-172763289  UCSC
Coordinates (T2T) chr5:173302190-173303403  UCSC
Coordinates (hg19) chr5:172189079-172190292  UCSC
Strand -
Parental Sequence NM_152274.5
Parental seq. overlap 1153 bp
Parental seq. overlap (%) 92%
Genomic Region Intergenic
Retrocopy Summary CCNQP4, located on chr5:172762076-172763289, is a retrocopy of the parental gene CCNQ. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CCNQ
Full Name cyclin Q
Also known as CycM|FAM58A
Coordinate chrX:153587925-153599165
Strand -
Gene summary Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin-box-fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CCNQP2
Bonobo Pan paniscus CCNQP2
Orangutan Pongo abelii CCNQP2
Gibbon Nomascus leucogenys CCNQP1
Gorilla Gorilla gorilla Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CCNQP4
GCCTCTCCTTCCGCCGGGGCCGCCGGGCCTCATGGAAGCCCCGGAGGGCGGCGGAGGGGGGCCTGCAGCGCGGGGCCCCGAGGGGCAACCGGCGCCCGAAGCCAGGGTGCACTTCCGAGTGGCGAGGTTCATCATGGAGGCAGGTGTCAAGCTAGGGATGAGGTCCATTCCCATTGCCACTGCTTGCACCATTTACCATAAGTTCTTTTGCAATACCAACCTGGACGCTTATGACCCTTACCTGATTGCCGTGTCTTCCATTTACTTGGCCGGCAAAGCGGAAAAGCAGCACCTGCGGACTCATGACATCATCAATGTGTCCAACAGGTACTTTAACCCGAGCGGTGAGCCCCTGGAATTGGAATCCCGCTTCTGGGAGCTCCGGGACAGCATTGTGCAGTGTGAGCTTCTCATGCTGAGAGTTCTGCGCTTCCAGGTCTCCTTCCAGCTTCCACACAAGTACCTGCTCCACTACCTGGTTTCCCTCAAAAACTCTGAACCGCCACAGCTGGCAGCGGACCCCGGTTGCCGTCACTGCCTGGGCCCTGTTGCGGGACAGCTACCACGGGGGTCTGTGCCTCCGTTTCCAGGCCCAGCACATCGCGGTGGCGGTGCTCTACCTGGCCCTGCAGGTCTACGGAGTTGAGGTGCCCGCCGAGGTTAAGGCTGAGAAGCCGTGGTGGCAGGTGTTTGGTGAAGACCTTACCAAGCCAATCATTGATAATATTGTGTCTGATCTCATTCAGATTTATACCATGGACACAGAGATCCCCTAAGGTCCTGGCCCAGGCCTGTCCAAAGAGAAGCCCAGGATGGTCGGCTGCCTGGGGACATTGCCACCACGTCGCCATGACGGCTGGTCCTCAGAGGACCAGCTGGGAGGACTGGTTGTGCTGCTGGAGAAGGGCTGGAGAAGGCGATGGCATGCTGCCGCTTTGACAGTCCCTAGCAGTCGCGGTGCAGGTGATGGGAGCCGCGCCTCCAGCGGCCAGGTCGGGAGTGCACTGCGTGCAGCTGATCCAAGGCAGCCATATCTGCTTTTGTCCTTTGAGAGGACTCTGACTACAATAGAGGCCTGACATCAATGAAAGGAAAATCATGAAATCGATGAGACTGAATCCCTAGGGATTTTTTAAAAGCCAGATCTATAGCGAGAATGAATGTGCAACATGGCTGAAATCTATTTTGTGTAATAAAAGGTGATGCAAGTCa
>NM_152274.5
ACCTCCAGTTCTGCCGGCTTCTGCGCGCCGGGGCCGCCTCTCCTTCCGCCGGTGCCGCGGCGCCTCATGGAAGCCccggagggcggcggaggggggcctgcagcgcggggcccggaggggcagccggcgcccgAAGCCAGGGTGCACTTCCGAGTGGCGAGGTTCATCATGGAGGCAGGTGTCAAGCTAGGGATGCGGTCCATTCCCATTGCCACTGCTTGCACCATTTACCATAAGTTCTTTTGCGAGACCAACCTGGACGCCTATGACCCTTACCTGATTGCCATGTCTTCAATTTACTTGGCCGGCAAAGTGGAAGAGCAGCACCTGCGGACTCGTGACATCATCAATGTGTCCAACAGGTACTTTAACCCAAGCGGTGAGCCCCTGGAATTGGACTCCCGCTTCTGGGAACTCCGGGACAGCATCGTGCAGTGTGAGCTTCTCATGCTGAGAGTTCTGCGCTTCCAGGTCTCCTTCCAGCATCCACACAAGTACCTGCTCCACTACCTGGTTTCCCTCCAGAACTGGCTGAACCGCCACAGCTGGCAGCGGACCCCTGTTGCCGTCACCGCCTGGGCCCTGCTGCGGGACAGCTACCATGGGGCGCTGTGCCTCCGCTTCCAGGCCCAGCACATCGCCGTGGCGGTGCTCTACCTGGCCCTGCAGGTCTACGGAGTTGAGGTGCCCGCCGAGGTCGAGGCTGAGAAGCCGTGGTGGCAGGTGTTTAATGACGACCTTACCAAGCCAATCATTGATAATATTGTGTCTGATCTCATTCAGATTTATACCATGGACACAGAGATCCCCTAAGGTCCTGGCCCAGGCCTGCCCAAAGAGAAGCCCAGGATGGTCGGCTGCCTGGGGACATTGTCACCACGTCGCCATGACGGCTGGTCCCCACAGGACCAGCTGGGAGGACTGGTTGTGCTGCTGGAGAAGGGCTGGAGAAGGCAATGGCATGCTGCCGCTTTGCCAGTCCCTAGAAGTCGCGGTGCAGGTGATGGTGGGAGCCGCGCCTCCAGCGGGCAGGCCGGGAGTGTACTGTGTGCAGCTGACCCAAGGCAGCCACATCTGCGTTTGTCCTTTGAGAGGACTTTGACTACAATACAGGCATGACATCAATGAAAGGAAAGTCATGAAATCGATGAGACTGAATCCCTACGGATTTCTTAAAAGCCAGATTTGTAGGGAGAATGAATGTGCAACGTGGCTGAAATCTATTTTGTGTAATAAAAGGTGATACAAGTCAA

Publications

PMID - Link Title