Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name FOXO1B
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr13). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:181099104-181100654  UCSC
Coordinates (T2T) chr5:181658740-181660290  UCSC
Coordinates (hg19) chr5:180526104-180527654  UCSC
Strand -
Parental Sequence NM_002015.4
Parental seq. overlap 1182 bp
Parental seq. overlap (%) 20%
Genomic Region Intergenic
Retrocopy Summary FOXO1B, located on chr5:181099104-181100654, is a retrocopy of the parental gene FOXO1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name FOXO1
Full Name forkhead box O1
Also known as FKH1|FKHR|FOXO1A
Coordinate chr13:40555667-40666641
Strand -
Gene summary This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FOXO1P1
Orangutan Pongo abelii FOXO1P1
Crab-eating macaque Macaca fascicularis FOXO1P1
Rhesus Macaca mulatta FOXO1P1
Baboon Papio anubis FOXO1P1
Golden snub-nosed monkey Rhinopithecus roxellana FOXO1P1
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FOXO1B
CATTTCGCCCTGGAACTAGCTCAAATGCTAGTACTGTTACTGGGAGACTTTCACCCATTATAGTCAAAGGAGACTATCTTGGAGATGGGGACGCACATTCTGTGGGGTACCCGCCATCTGCGGCAAAGATGCCCCTACTCCACCCAGTCTGAGACAAGCAATCCTGAAACGTGGAAAGCTTTCTGAGTGATCTCAGTCTTATCTCCTCACCAACATCATTAACTGTGTCCACCCAGTCCTCACCTGGCACCATGATGCAGCAGACGCCAGCTACTCCTTTGTGCCACCAAACACCAGTCTGAATTCGCCCAGCCAAACTGCAAAAAACAGACGTAGGGCCAGTCCAACATGAGCCCTTTGCCCCAGATGCAAACACTCCAGGAGCACAAATCAAGTTACGGAGCTGTGAGTCCGTGTAACTGTGTAGCGGGACTCCTGGAGGAGATGCTGACTTCTGACTCTCCTCCCCATAATGACATTATGACACCAGCTGATCCTGGAGTAGCCCAATCCAACAGTCGGTTTCTGGGCCAGAATACCATGATGGGCCTTAATTCAGCCATGTCAACCTATGGCAGCCAGGCATCTGGATACAAAATGAGGCATCCCAGCTCCCATATCCACCCTGGGCATGCTCAGCAGACATATGCAGCTTACGGCCGTGCCCTGTCTCACACGGAAAACACCAAGCCCCACACCTCAGGTGTGAACCAACTGACCCCAGTGAAGACACCTTTGCAAGTGCCTCTGCCCCACCCCATGCAGATGAGTGCCCTGGGGGGCTACTCCTCGGTGAGCAGCTGCAGTGGTTATGGCAGAATGGACCTTCTCCACCAGGAGAGGCTTCCAAGTGACTTGGACGGCATGCTCACTGAGCCCTTGGACTGTGACATGGAATCCAAATCTTCATTTGGAATGACCTCATGGATGGAGACACGCTGGATTTTTCACCTTGGCAATGTTTTGCCCAGCCAAAGCTCCTCACACAGTGTCAAGACAAGGACACATAGCTGCGTGTCAGGCTGAGAACTGGTGAGCCCGCTACACTTAAAAGTACTTCATGGGCAGCAGCGCAGGGGCAGCTCGTCCCGTCGCACCGCGTCGCGCAGCCTGTCCCACGCCGACCTCAGCACCAGGGCCGACGAGAGCTCGGCGGAGAAGCGGCTCGCGCTGTCGCAGATCTGCGAGTGGATGGTCAAGAGCGTGCCCTGCTCCCAGGGCGACAGCAACAGCTCGGCGGGCTGCAGGAATTCACTTCGTCATCTTCTGTCCCTACACAGCAAGCTGACTCGCGCGCAGAATGAAGGAACTGGAAAAAGTGCTCGGTGGACGCTGGATCCAGAGGGCGGCAAGGGTGGGAGATCTCTTAGGACAAGAGCTGCATCCATGGACAGCAGCAGCAAATGCGCTCGGAGCCTAAGTCAAGCTGCCACGAAAAAAGCATCCTGCAGTCTAGCCAGGGGGGTGCCGGGGACAGCCCTGGACCCCAGTTTTCCAGATGGCCTGCAAGCCCt
>NM_002015.4
GATCCCGTAAGTCGGGCGGCCTGGTAGTCgcagcagccgctgccgcagccgccacattcaacaggcagcagcgcagcGGGCGCGCCGCTGGGGAGAGCAAGCGGCCCGCGGcgtccgtccgtccttccgtccgCGGCCCTGTCAGCTGGAGCGCGGCGCAGGCTCTGCCCCGGCCCGGCGGCTCTGGCCGGCCGTCCAGTCCGTGCGGCGGACCCCGAGGAGCCTCGATGTGGATGGCCCCGCGAAGTTAAGTTCTGGGCTCGCGCTTCCACTCCGCCGCGCCTTCCTCCCAGTTTCCGTCCGCTCGCCGCACCGGCTTCGTTCCCCCAAATCTCGGACCGTCCCTTCGCGCCCCCTCCCCGTCCGCCCCCAGTGCTGCGTTCTCCCCCTCTTGGCTCTCCTGCGGCTGGGGGAGGGGCGGGGGTCACCATGGCCGAGGCGCCTCAGGTGGTGGAGATCGACCCGGACTTCGAgccgctgccccggccgcgctcgtgcacctggccgctgccCAGGCCGGAGTTTAGCCAGTCCAACTCGGCCACCTCCAGCCCGGCGCCGTCGGGCAGCGCGGCTGCCAACCCCGACGCCGCGGCGGGCCTGCCCTCGGCCTCGGCTGCCGCTGTCAGCGCCGACTTCATGAGCAACCTGAGCTTGCTGGAGGAGAGCGAGGACTTCCCGCAGGCGCCCGGCTCCgtggcggcggcggtggcggcggcggccgccgcggccgcCACCGGGGGGCTGTGCGGGGACTTCCAGGGCCCGGAGGCGGGCTGCCTGCACCCAGcgccaccgcagcccccgccgcccgggccgctgtcgcagcacccgccggtgccccccgccgccgctgggccgctcgcggggcagccgcGCAAGAGCAGCTCGTCCCGCCGCAACGCGTGGGGCAACCTGTCCTACGCCGACCTCATCACCAAGGCCATCGAGAGCTCGGCGGAGAAGCGGCTCACGCTGTCGCAGATCTACGAGTGGATGGTCAAGAGCGTGCCCTACTTCAAGGATAAGGGTGACAGCAACAGCTCGGCGGGCTGGAAGAATTCAATTCGTCATAATCTGTCCCTACACAGCAAGTTCATTCGTGTGCAGAATGAAGGAACTGGAAAAAGTTCTTGGTGGATGCTCAATCCAGAGGGTGGCAAGAGCGGGAAATCTCCTAGGAGAAGAGCTGCATCCATGGACAACAACAGTAAATTTGCTAAGAGCCGAAGCCGAGCTGCCAAGAAGAAAGCATCTCTCCAGTCTGGCCAGGAGGGTGCTGGGGACAGCCCTGGATCACAGTTTTCCAAATGGCCTGCAAGCCCTGGCTCTCACAGCAATGATGACTTTGATAACTGGAGTACATTTCGCCCTCGAACTAGCTCAAATGCTAGTACTATTAGTGGGAGACTCTCACCCATTATGACCGAACAGGATGATCTTGGAGAAGGGGATGTGCATTCTATGGTGTACCCGCCATCTGCCGCAAAGATGGCCTCTACTTTACCCAGTCTGTCTGAGATAAGCAATCCCGAAAACATGGAAAATCTTTTGGATAATCTCAACCTTCTCTCATCACCAACATCATTAACTGTTTCGACCCAGTCCTCACCTGGCACCATGATGCAGCAGACGCCGTGCTACTCGTTTGCGCCACCAAACACCAGTTTGAATTCACCCAGCCCAAACTACCAAAAATATACATATGGCCAATCCAGCATGAGCCCTTTGCCCCAGATGCCTATACAAACACTTCAGGACAATAAGTCGAGTTATGGAGGTATGAGTCAGTATAACTGTGCGCCTGGACTCTTGAAGGAGTTGCTGACTTCTGACTCTCCTCCCCATAATGACATTATGACACCAGTTGATCCTGGGGTAGCCCAGCCCAACAGCCGGGTTCTGGGCCAGAACGTCATGATGGGCCCTAATTCGGTCATGTCAACCTATGGCAGCCAGGCATCTCATAACAAAATGATGAATCCCAGCTCCCATACCCACCCTGGACATGCTCAGCAGACATCTGCAGTTAACGGGCGTCCCCTGCCCCACACGGTAAGCACCATGCCCCACACCTCGGGTATGAACCGCCTGACCCAAGTGAAGACACCTGTACAAGTGCCTCTGCCCCACCCCATGCAGATGAGTGCCCTGGGGGGCTACTCCTCCGTGAGCAGCTGCAATGGCTATGGCAGAATGGGCCTTCTCCACCAGGAGAAGCTCCCAAGTGACTTGGATGGCATGTTCATTGAGCGCTTAGACTGTGACATGGAATCCATCATTCGGAATGACCTCATGGATGGAGATACATTGGATTTTAACTTTGACAATGTGTTGCCCAACCAAAGCTTCCCACACAGTGTCAAGACAACGACACATAGCTGGGTGTCAGGCTGAGGGTTAGTGAGCAGGTTACACTTAAAAGTACTTCAGATTGTCTGACAGCAGGAACTGAGAGAAGCAGTCCAAAGATGTCTTTCACCAACTCCCTTTTAGTTTTCTTGGTTaaaaaaaaaaacaaaaaaaaaaaCCCTCCTTTTTTCCTTTCGTCAGACTTGGCAGCAAAGACATTTTTCCTGTACAGGATGTTTGCCCAATGTGTGCAGGTTATGTGCTGCTGTAGATAAGGACTGTGCCATTGGAAATTTCATTACAATGAAGTGCCAAACTCACTACACCATATAATTGCAGAAAAGATTTTCAGATCCTGGTGTGCTTTCAAGTTTTGTATATAAGCAGTAGATACAGATTGTATTTGTGTGTGTTTTTGGTTTTTCTAAATATCCAATTGGTCCAAGGAAAGTTTATACTCTTTTTGTAATACTGTGATGGGCCTCATGTCTTGATAAGTTAAACTTTTGTTTGTACTACCTGTTTTCTGCGGAACTGACGGATCACAAAGAACTGAATCTCCATTCTGCATCTCCATTGAACAGCCTTGGACCTGTTCACGTTGCCACAGAATTCACATGAGAACCAAGTAGCCTGTTATCAATCTGCTAAATTAATGGACTTGTTAAACTTTTGGAAAAAAAAAGATTAAATGCCAGCTTTGTACAGGTCttttctatttttttttgtttattttgttatttGCAAATTTGTACAAACATTTAAATGGTTCTAATTTCCAGATAAATGATTTTTGATGTTATTGTTGGGACTTAAGAACATTTTTGGAATAGATATTGAACTGTAATAATGTTTTCTTAAAACTAGAGTCTACTTTGTTACATAGTCAGCTTGTAAATTTTGTGGAACCACAGGTATTTGGGGCAGCATTCATAATTTTCATTTTGTATTCTAACTGGATTAGTACTAATTTTATACATGCTTAACTGGTTTGTACACTTTGGGATGCTACTTAGTGATGTTTCTGACTAATCTTAAATCATTGTAATTAGTACTTGCATATTCAACGTTTCAGGCCCTGGTTGGGCAGGAAAGTGATGTATAGTTATGGACACTTTGCGTTTCTTATTTAGGATAACTTAATATGTTTTTATGTATGTATTTTAAAGAAATTTCATCTGCTTCTACTGAACTATGCGTACTGCATAGCATCAAGTCTTCTCTAGAGACCTCTGTAGTCCTGGGAGGCCTCATAATGTTTGTAGATCAGAAAAGGGAGATCTGCATCTAAAGCAATGGTCCTTTGTCAAACGAGGGATTTTGATCCACTTCACCATTTTGAGTTGAGCTTTAGCAAAAGTTTCCCCTCATAATTCTTTGCTCTTGTTTCAGTCCAGGTGGAGGTTGGTTTTGTAGTTCTGCCTTGAGGAATTATGTCAACACTCATACTTCATCTCATTCTCCCTTCTGCCCTGCAGATTAGATTACTTAGCACACTGTGGAAGTTTAAGTGGAAGGAGGGAATTTAAAAATGGGACTTGAGTGGTTTGTAGAATTTGTGTTCATAAGTTCAGATGGGTAGCAAATGGAATAGAACTTACTTAAAAATTGGGGAGATTTATTTGAAAACCAGCTGTAAGTTGTGCATTGAGATTATGTTAAAAGCCTTGGCTTAAGAATTTGAAAATTTCTTTAGCCTGTAGCAACCTAAACTGTAATTCCTATCATTATGTTTTATTACTTTCCAATTACCTGTAACTGACAGACCAAATTAATTGGCTTTGTGTCCTATTTAGTCCATCAGTATTTTCAAGTCATGTGGAAAGCCCAAAGTCATCACAATGAAGAGAACAGGTGCACAGCACTGTTCCTCTTGTGTTCTTGAGAAGGATCTAATTTTTCTGTATATAGCCCACATCACACTTGCTTTGTCTTGTATGTTAATTGCATCTTCATTGGCTTGGTATTTCCTAAATGTTTAACAAGAACACAAGTGTTCCTGATAAGATTTCCTACAGTAAGCCAGCTCTATTGTAAGCTTCCCACTGTGATGATCATTTTTTTGAAGATTCATTGAACAGCCACCACTCTATCATCCTCATTTTGGGGCAGTCCAAGACATAGCTGGTTTTAGAAACCCAAGTTCCTCTAAGCACAGCCTCCCGGGTATGTAACTGAACTTGGTGCCAAAGTACTTGTGTACTAATTTCTATTACTACGTACTGTCACTTTCCTCCCGTGCCATTACTGCATCATAATACAAGGAACCTCAGAGCCCCCATTTGTTCATTAAAGAGGCAACTACAGCCAAAATCACTGTTAAAATCTTACTACTTCATGGAGTAGCTCTTAGGAAAATATATCTTCCTCCTGAGTCTGGGTAATTATACCTCTCCCAAGCCCCCATTGTGTGTTGAAATCCTGTCATGAATCCTTGGTAGCTCTCTGAGAACAGTGAAGTCCAGGGAAAGGCATCTGGTCTGTCTGGAAAGCAAACATTATGTGGCCTCTGGTAGTTTTTTTCCTGTAAGAATACTGACTTTCTGGAGTAATGAGTATATATCAGTTATTGTACATGATTGCTTTGTGAAATGTGCAAATGATATCACCTATGCAGCCTTGTTTGATTTATTTTCTCTGGTTTGTACTGTTATTAAAAGCATATTGTATTATAGAGCTATTCAGATATTTTAAATATAAAGATGTATTGTTTCCGTAATATAGACGTATGGAATATATTTAGGTAATAGATGTATTACTTGGAAAGTTCTGCTTTGACAAACTGACAAAGTCTAAATGAGCACATGTATCCCAGTGAGCAGTAAATCAATGGAACATCCCAAGAAGAGGATAAGGATGCTTAAAATGGAAATCATTCTCCAACGATATACAAATTGGACTTGTTCAACTGCTGGATATATGCTACCAATAACCCCAGCCCCAACTTAAAATTCTTACATTCAAGCTCCTAAGAGTTCTTAATTTATAACTAATTTTAAAAGAGAAGTTTCTTTTCTGGTTTTAGTTTGGGAATAATCATTCATTAAAAAAAATGTATTGTGGTTTATGCGAACAGACCAACCTGGCATTACAGTTGGCCTCTCCTTGAGGTGGGCACAGCCTGGCAGTGTGGCCAGGGGTGGCCATGTAAGTCCCATCAGGACGTAGTCATGCCTCCTGCATTTCGCTACCCGAGTTTAGTAACAGTGCAGATTCCACGTTCTTGTTCCGATACTCTGAGAAGTGCCTGATGTTGATGTACTTACAGACACAAGAACAATCTTTGCTATAATTGTATAAAGCCATAAATGTACATAAATTATGTTTAAATGGCTTGGTGTCTTTCTTTTCTAATTATGCAGAATAAGCTCTTTATTAGGAATTTTTTGTGAAGCTATTAAATACTTGAGTTAAGTCTTGTCAGCCA

Publications

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