Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PPP4R2P4
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:287683-290548  UCSC
Coordinates (T2T) chr5:277706-280575  UCSC
Coordinates (hg19) chr5:287798-290663  UCSC
Strand -
Parental Sequence NM_174907.4
Parental seq. overlap 1064 bp
Parental seq. overlap (%) 16.1%
Genomic Region Intragenic (PDCD6)
Retrocopy Summary PPP4R2P4, located on chr5:287683-290548, is a retrocopy of the parental gene PPP4R2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PPP4R2
Full Name protein phosphatase 4 regulatory subunit 2
Also known as PP4R2
Coordinate chr3:72996743-73069198
Strand +
Gene summary The protein encoded by this gene is a regulatory subunit of the serine/threonine-protein phosphatase 4 complex. In addition to being required for efficient DNA double strand break repair, this complex plays a role in organization of microtubules at centrosomes and processing of spliceosomal snRNPs. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

Homology

Species Scientific Name Retrocopy
Bonobo Pan paniscus PPP4R2P4
Gorilla Gorilla gorilla PPP4R2P4
Gibbon Nomascus leucogenys PPP4R2P2
Chimpanzee Pan troglodytes Without Homology
Orangutan Pongo abelii Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PPP4R2P4
TATTTTAAGGGGGGAAATGTTATATTTTTCTGTTTCCATAAGAGATGAATACAGTGGATACTTTTTCTATTGGTAGTGATTGAGTTCACCTCTTTCAGAAGACATTTTCTTTCTCTTCTGAGTAACTGAAATAAAATCTGGCCTTTGTGAAACCCTAGAAATCTTAAGTCTGTTGAAATACCAGGTTAAACACATTCCAAGAGATCTGTTCAAACTCAAATTCTTTTGTATACTTCTGAGGTGCCTGAGAAACAGACTTCATTATTTATGAGAAAATATTCTTTATTTTTGGAAATTGTGTTCAAATGTTAGCTTACTATTTTGTAGAATGAATGTTTATGAAGCTGATATGAGGCCATCTCAGAACCAAGCAGGTTCCTTGAACTTTTGCTTGCTTTTCTGAACATTGCGAATATTACACGTCTTTCCAAATTATTCTAGAGTATGCAAGTGTCAATGGTATGAAACACCATTGTACTGGAAGAATTAATATATTACTTTAATATGTACCTGAGCTAAATGACTGAAGCTTTAGGGGTGCATAGAAACCACCATAATTTGTATGACATTTTGAAGTGAATTAAATATTTTTGAACATGATGGTCTGGGCAAATCAGTGGTTTGTGTATAGATTTTTTTTTTTTAATTTAGGATTAAAGTTTTTAAACTGGAAGGTAATCATAATTTTGAAAAGTTTTTTGAGATTATCACATTTAGTTTATACATATGAAAGAAGGTTTTTGTCTTGTCTCTTTCTGATAGCTCTAGCAGTTTTCACATTTTGGTCATAGTTTCAACATTTTAACATGTGAATAACAGGGTTTCATGCTGGTTTCCAGATTTTATTGTCCGGCTACGTACAATGGAACTTTAAGTGTATTGAGAGACCATCTGTAAAAGGGAGGAGTAAGAAGATCCTCAAATTCTTGTATTCATTGCTTTCGTGAAAGAATTGTACATAATAGAACTCCTTGTAATGCCGACATTGGGCTTTTCTCCCACCTGTATGTAGTTGTTGCTGAATTTCAGGGAATGTGATTTGAATTATAGAACATCAGAATTCATGAAACTTAACTGTGGAGGTATTCTGAAAATAAAATTTAAGTACAACAACATTTGCTTATTTTTAGAGTCTTTTATGACATCAAGAGAAATGATCCCGGAAAGAAAAAATCAAGAAAAATAATCTGATGATGCCTCAACTGTGAATGAAGAGACTTTTGAGGAAAATAATCAAATGGAGGAATCTGATGTGTCTCAAGCTGAGAAAGATTTACTACATTCCGAAGGTAATGAAAACGAAGGCCCTGAAAGTAGTGGTTCTTCTGACTGCCGTGAAACAGAAGAATTAGTAGGATCTAATTCCAGTAAAACTGGAGAGATTCTTTCAGAATCATCCATGGAAAATGATGACGAAGCCACAGAAGTCACCGATGAACCAATGGAACAAGACTATTTAGAAACATTTAGATGCAGTATTTTACATACAGTTCTGGTTTTAACGCCGTATAAAACTTTTATGTAAAAAAGTCCACGTTTAGTTTTACAAGAAAAGCAGGTTGTAAAACAATAAAGTACTTTATGGATAATTCCTGGAAGAGTTGTACACGTAAGAACTGTGAATATCAGCTCCTCTGGGTCCTGTTTACCTTACCGCTGAGGCGCCATGTTGGAGGGTTGGTGGTAGTGGCTTGGGGAGATGCTCGCTCTGTTGGTCTCACTCTCTCACATGCTTCCCCTGGCTCCCTTCGTTCCCCCCACCCAACTTGGCCTGCATGCGGGAGTGTGTGCGAGGGAGTGGGAGGACGTCGGGGGGTGGGGGGAGGCATTCCGGTCCCCAAGAGACCTGCGGAGGGAGGCGGAGGCTGTGAGGGACTCCAGGAAGCCATGGACGTTGAGAGTCTCCAGGAGGCGCTGAAAGATTTTGAGAAGAGGGGAAAAAGGAAGTTTGTCCTGTCCTGGATCAGTTTCTTTGTCATATAGCCAAGACTGGAGAAACAGATTCAGTGGTCCCAATTTAAAGGCTATTTTATTTTCAAACTGGAGAAAGTGATGGATGATTTCAGAACTTCAGCTCCTGAGCCAAGAGGTCCTCCCAACCCTAATGTCGAATATATTCCCTTTGATGAAATGAAGGAAAGAATACTGAGAATTGTCACTGGATTTAACAGTATCCCTTTTACTATTCAGCGACTATGTGAATTGTTAACAGATCCAAGGAGAAACTATACAGGAACAGACAAATTTCTCAGAGGAGTAGAAAAGGATGTGATGGTTGTTAGCTGTGTTTATCCTTCTTCAGAGAAAAACAATTCCAATAGTTTAAATCGAATGAATGGTGTTATGTTTCCTGGAAATTCACCAAGCTATCCTGAGAGGTCTAATGTAAATGGGCCTGGGACACCCAGACCACGTAATCGACCAAAGGTTTCTTTGTCAGCCCCCATGACAACAAATGGGTCGCCTGACAGCACAGACAGCAAAGAGGTAAATTTGCAGCAAAATGAAGAGAAAAATCACAGTGACTCTTCGACATCTGAATCAGAAGTTTGCTCAGTGAGCCCTTTGAAAAATAAACATCCAGATGAAGATGCTGTGGAAGCTGAGGGGCATGAGGTAAAAAGACTCATGTTTGACAAAAAAGGCGAAGTCAGAGAAACAGCCATTCAAGCGACTTGCAGCGAAATTTCTTCGGTTATGGTAGAAGAAACAGAAGCATCACCTTCATCTCAGGATAAAGACAAAGAAAGCCGTTGTACCCGGCAGCGCGTACa
>NM_174907.4
GGGCGCCATGTTGGAGGGTTGGTGGTAGCGGCTTGGGGAGGTGCTCGCTCTGTCGGTCTTGCTCTCTCGCACGCTTCCCCCGGCTCCCTTCGTTTCCCCCCCCCGGTCGCCTGCGTGCCGGAGTGTGTGCGAGGGAGGGGGAGGGCGTCGGGGGGGTGGGGGGAGGCGTTCCGGTCCCCAAGAGACCCGCGGAGGGAGGCGGAGGCTGTGAGGGACTCCGGGAAGCCATGGACGTCGAGAGGCTCCAGGAGGCGCTGAAAGATTTTGAGAAGAGGGGGAAAAAGGAAGTTTGTCCTGTCCTGGATCAGTTTCTTTGTCATGTAGCCAAGACTGGAGAAACAATGATTCAGTGGTCCCAATTTAAAGGCTATTTTATTTTCAAACTGGAGAAAGTGATGGATGATTTCAGAACTTCAGCTCCTGAGCCAAGAGGTCCTCCCAACCCTAATGTCGAATATATTCCCTTTGATGAAATGAAGGAAAGAATACTGAAAATTGTCACTGGATTTAATGGTATCCCTTTTACTATTCAGCGACTATGTGAATTGTTAACAGATCCAAGGAGAAACTATACAGGAACAGACAAATTTCTCAGAGGAGTAGAAAAGAATGTGATGGTTGTTAGCTGTGTTTATCCTTCTTCAGAGAAAAACAATTCCAATAGTTTAAATCGAATGAATGGTGTTATGTTTCCTGGAAATTCACCAAGCTATACTGAGAGGTCTAATATAAATGGGCCTGGGACACCCAGGCCACTTAATCGACCAAAGGTTTCTTTGTCAGCCCCCATGACAACAAATGGGTTGCCTGAGAGCACAGACAGCAAAGAGGCAAATTTGCAGCAAAATGAGGAGAAAAATCACAGTGACTCTTCGACCTCTGAATCAGAAGTTTCCTCAGTGAGCCCTTTGAAAAATAAACATCCAGATGAAGATGCTGTGGAAGCTGAGGGGCATGAGGTAAAAAGACTCAGGTTTGACAAAGAAGGTGAAGTCAGAGAAACAGCCAGTCAAACGACTTCCAGCGAAATTTCTTCAGTTATGGTAGGAGAAACAGAAGCATCATCTTCATCTCAGGATAAAGACAAAGATAGCCGTTGTACCCGGCAGCACTGTACagaagaggatgaagaagaggatgaagaggaagaagaagAGTCTTTTATGACATCAAGAGAAATGATCCCAGAAAGAAAAAATCAAGAAAAAGAATCTGATGATGCCTTAACTGTGAATGAAGAGACTTCTGAGGAAAATAATCAAATGGAGGAATCTGATGTGTCTCAAGCTGAGAAAGATTTGCTACATTCTGAAGGTAGTGAAAACGAAGGCCCTGTAAGTAGTAGTTCTTCTGACTGCCGTGAAACAGAAGAATTAGTAGGATCCAATTCCAGTAAAACTGGAGAGATTCTTTCAGAATCATCCATGGAAAATGATGACGAAGCCACAGAAGTCACCGATGAACCAATGGAACAAGACTAACTATTTAGAAACATTTAGATGCAGTATTTTACATACAGTTCTGGTTTTAACACTGTATAAAACTTTTGTGTAATAAAATGGACCTTTAGTTTTACAAGAGAAGCAGGTTGTAAAATAAAGTACTTTATGGATAATTCCTGAAAGAGTTGTACATGTAAGAACTGTGAATATCAGCTCCTCTGGGTCCTGCTTACCTTACCGCTGACTTTTCTTTCTTTCTTTTTTTGGTCTGGGCAAATCAGTGGTTTGTGTATAGATTTTTTTTTTTTTTTAATTTAGGATTGAAGTTTTTAAACTGGAAAGTAATTACAATTTTGAAAAGTTTTTTGAGATTATCACATTTAGTTTATACATATGCAAGAAGCTTTTTGTCTTGTCTCTTTCTGATAGCTCTAGCAGTTTTCATATTTTGGTCATAGTTTCAACATTTTAACATGTGAATTATAGGGTTTCATGCTGGTTTCCAGATTTTATTGTTTGGCTACGTACAATGGAACTTTAAGTCatatatacatacatatatatatatatatatatataATTCTAAGGGGGGAAATGTTATATTTTTCTGTTTCTATAAGAGATGAATACAGTGGATACTTTTTCTATTGGTAATGATTGAGTTCACCTCTTTCAGAAGACATTTTCTTTCTCTTCTGAGTAATTGAAATAAAATCTGGCCCTTGTGAAACCCTGGAAATCTTAAGTCTGTTGAAATACCAGGTTAAACACATTCCAAGAGATCTGTTCAAACTCAAATTCTTTTGTATACTTCTGAGGTGCCTGAGAAAAAGACTTCATTATTTATGAGAAAATATGCTTTATCTTGGAAATTGTGTTCAAATGTTAGCTTACTATTTTGTAGAATGAATGTTTATGAAGCTGATATGAGACCATCTCAGAAGAACCAAGTAGGTTCCTTGACCTTTTGCTTGCTTTTCTGAACATTGTGAATATTACACATGTCTTTCTAAATTATTCTAGGGTATGCAAATGTCAATGGTATGAAACACCACTGTACTGGAAGAATTAATATATTACTTTAGTATGTACCTGAGCTAAATGACTGAAGCTTTAGGGGTGCATAGAAACCACCATAATTTGTATGACATTTTGAAGTGAATTAAATATTTTTGAACATGCTTCTTCGACAGCCAGTGTTATATTTTTCAGATCAACACAAAGCACAATGATTACTCGAAATTCAGTATTTTCAAATTTACATATTTAAAGTCATGCAAGCTGTAACTTCCCTGTCAAAATTACTGGCTGCCAAATTTATACCTGTTTCTTCAGCTGTACCTTTTGATATTTAAAGTTTTTAAATTTCTGTAAAGTAGATTTTGTAGAATGTAATGTGTTCACTGCCTTTGTGAAGCGGTATATAATTGTATAATTTCTGTGTGTAAACTGAATGCTTGGGCTTTCAATACAGTATTCATATAAAGCAATAAATATTAATGTTATGAAATATTTGACTACATTTTTATCAAAATATGAAAGAATCCCCCCTTTTTTAGTTTCAGATACCTGAACTACACAGATGAGCTTCTAAAACTGATGCAAACAGTTTCTGACACTGTATAATATGCTTTTGGGTGATTTGGGGGGCAACCACAAGTTTTGCGTTTTGACTACTTAAATCATCATGGCTATAAATACCAAAACGATTTGGATCCATTTATGTTTGTAGGATAATATACTACTGACTGACTTGACTGTCAGGTTCACAACAGCTAGATGATATATTTATGACTATGTCTAATAGTTGAAATAAAATCTGAATATTGATTTACTATACCCAAGAGGGGAGAAAAATTAACCATTGTAAATTTTTAAAAAATTTTTCAAAAATGTTAAAATGAGGCAAATTTAAGTTTACAAATTTTGAAATTTTCTTTTGAATATTTATGAAATTGTCAGTAAACTTACCTAAGATCCTGTGACCTTTTGATATTTTTTATTTTAATTGTAGTGCCATGGACCATTTGTAAACAAATTGATTTACTTTTGTTGGTTGTAAGTTGAAGATTTAGCATTATGACTTTGAGGTCTGTGGTTTTATTTGTAAACTTGCAATTGCTATATTTGCAAGGGCAAATGTATTTCTTTATTAAATAAAGTACAATAATGGTGAATGTACCAAAATGACATCACTTAACTCTATGAGAGATCTGCATTTTAATCTATAGTTTAATAGTTTTAATATTTATTAGATATTCATATGTTGATCATAGATCAAACTTGTTGCTGTTTATACAGATAATTGTAGAATGCTCATGGAATATCTTTAGGGTAGGTGGAATACTTCTGTAGTTAAATTGGGAAACCTTGTTCAGCTGGTTTTAGATATTGATGGCCATTTGGAAGTAAATTTCCGCAGGTATTCATAGGTGCACTTAACACAGACTTTGCTTAATGAAAATGTCAGTTCTAATAGTAACTGATTCACTTCTGAACAGAAGTGATTTTAGGCATATTTCTTAACATATATCAAGCAAAGTCCTGTTAAAAGATCTAAATGAAGAATGGAGACCTCAGTGATTAAAGATATTTTGTTTCTGACCTTGAGCAGATTGCTTACCTGTTCTCTAGACTATAACCCAACATGTAAAAAAAATTTGAAGATGGTGATGAGGAAAGTGAGatatatatatatatatgtattatGTTTCTAGCACTTTTCCCTTTTAAAAAGTGAAAATATCCTTGTACATTTTTGAAAAATATATTTTCAGTTCTGAAAAATGTAGCAGAAGTAGTGAAAATGTCATATTTTAAATGTTGATTATTAGATAAATTTAACCTGCTTAGGGTTTATTGTAACTACACCTTTCAGACGTGTGTTTTGGAGTAGTGGAATTGCCAGCCAGGCCCTGTGGCTTGGAAAGGCATCCCAGAAATCCTCGGCCAGAAGGTGTGGCTTGTTAAAGCATTGAGATTCAGAGTATTTTGTTTTGCCGGTGTAGATAGGCATGTATTTATGCATTTTTGCATTTGTAAAATCAACTTTTCAAATAATGTAAATGTAATATACTAGTTTACTTAAAGGTACTTGGGCAGAATCTAAAGCTGCTACAATGTTTGATTATGAAAAAAATGTAACATGGTAAGGATGAAAATGCAACTTACAAAACCAAAGGAATTAAAAATTTTCGGTAGTGTTTCAAATTGTCTTCTGAACAGGAATTTAACATTGGTTTTGATGAAGGTGAGGGTCAGTTCTCAAGATTTGTGCTAATCATAAAATGAATGAATGCAAAACACCTTGTAATTTCATATGGAATTATAAAAATTAGGTTTGCTGGGTTTTGGCCTAATAAGAGTGCTAGTATGTATTGGTTAGACTACATCTTACTATTTCACATTTTAAAAATCAGTACACTCTTCAGGATTTTCTTTTATTTCAACTTGGAGCCTAGATTACTTTGCCAAATGTATTATTTTCATAATGCAATAAAATATAAATTAGAATA

Publications

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