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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TOMM7P2
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:31923300-31923727  UCSC
Coordinates (T2T) chr5:32036927-32037354  UCSC
Coordinates (hg19) chr5:31923406-31923833  UCSC
Strand +
Parental Sequence NM_019059.5
Parental seq. overlap 409 bp
Parental seq. overlap (%) 94.2%
Genomic Region Intragenic (PDZD2)
Retrocopy Summary TOMM7P2, located on chr5:31923300-31923727, is a retrocopy of the parental gene TOMM7. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TOMM7
Full Name translocase of outer mitochondrial membrane 7
Also known as TOM7
Coordinate chr7:22812974-22822849
Strand -
Gene summary This gene encodes a subunit of the translocase of the outer mitochondrial membrane. The encoded protein regulates the assembly and stability of the translocase complex. [provided by RefSeq, Oct 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TOMM7P2
Bonobo Pan paniscus TOMM7P2
Gorilla Gorilla gorilla TOMM7P2
Orangutan Pongo abelii TOMM7P2
Gibbon Nomascus leucogenys TOMM7P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TOMM7P2
CTCCCTTTCGGATTCCCGATGCGGTGGTTGCTGTAAGGGGTCCTCCCTGTGCCACACGGCCATCGCCATGGTGAAGCTGAGCAAAGAGGCCAAGCAGAGACTGCAGCAGCTCTTCAACGGGGGCCAGTTTGCCATCCACTTGGGCTTTATCCCTCTTGTGATTTACCTGGGATTTAAGAGGGGTGCAGATCCTGGAATGTCTGAACCAACTGTTCTGAGCCTACTTTGGGGATAAAGGATTATTTGGTCTTCTGGATTTGGAGGCAATCAGTGGACAGCATGAAAGATGTGTGCTCTGGCTCGGATAAGAGATGGGACATCATTCAGTCACTAGTTGGATGGCACAAGGCTCTTCACAGATGAACCTGTAGCAGAGTGGAACTTGTACTAACTTATGATAGAATGTATCAGAATAAATGTTTTTAACA
>NM_019059.5
CCTTTCCCTTTCGGATTCCCGACGCTGTGGTTGCTGTAAGGGGTCCTCCCTGCGCCACACGGCCGTCGCCATGGTGAAGCTGAGCAAAGAGGCCAAGCAGAGACTACAGCAGCTCTTCAAGGGGAGCCAGTTTGCCATTCGCTGGGGCTTTATCCCTCTTGTGATTTACCTGGGATTTAAGAGGGGTGCAGATCCCGGAATGCCTGAACCAACTGTTTTGAGCCTACTTTGGGGATAAAGGATTATTTGGTCTTCTGGATTTGGAGGCAATCAGCGGACAGCATGGAAGATGTGTGCTCTGGCTCGGATAAGAGATGGGACATCATTCAGTCACTAGTTGGATGGCACAAGGCTCTTCACAGACGCATCTGTAGCAGAGTGGAACTTGTACTAACTTATGATAGAATGTATCAGAATAAATGTTTTTAACAGTG

Publications

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