Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SERBP1P6
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:42465396-42468952  UCSC
Coordinates (T2T) chr5:42720890-42724446  UCSC
Coordinates (hg19) chr5:42465498-42469054  UCSC
Strand -
Parental Sequence NM_001018067.2
Parental seq. overlap 838 bp
Parental seq. overlap (%) 12.3%
Genomic Region Intragenic (GHR)
Retrocopy Summary SERBP1P6, located on chr5:42465396-42468952, is a retrocopy of the parental gene SERBP1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SERBP1
Full Name SERPINE1 mRNA binding protein 1
Also known as CGI-55|CHD3IP|HABP4L|PAI-RBP1|PAIRBP1
Coordinate chr1:67407810-67430402
Strand -
Gene summary Enables SUMO binding activity; mRNA 3'-UTR binding activity; and ribosome binding activity. Involved in PML body organization. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SERBP1P4
Bonobo Pan paniscus SERBP1P4
Gorilla Gorilla gorilla SERBP1P5
Orangutan Pongo abelii SERBP1P3
Gibbon Nomascus leucogenys SERBP1P2
Green monkey Chlorocebus sabaeus SERBP1P1
Crab-eating macaque Macaca fascicularis SERBP1P3
Rhesus Macaca mulatta SERBP1P3
Baboon Papio anubis SERBP1P3
Golden snub-nosed monkey Rhinopithecus roxellana SERBP1P1
Marmoset Callithrix jacchus SERBP1P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SERBP1P6
AAAAATAAAAAACACAAAAAGAAGAAGGAATAAGACAAGTTGGAAGAAGACCTGCTCAACAACTTCACGGTGAAGGGAAAATAACTGATAGAAGACCAGAAAGGAGACCACCTTGTGAACGAAGACTTGAAAAGCCACTTGATGAAAGGGGTGAAGGAGGCGAATTTTCAGTTGATAGACTGATTATTGACCGACCTATTCAAGGTCATGGTGGTCTTGGAAGAGGTCGAGAGGGCAGTGGACGTGAAATGGGCCAAGGAGATGGATTTGATTCTCGTGGCAAACGTGAATTTGATAGGTATAGTGGAAGTGATAGATCTTTTTTTTCACATTACAGTGGCCTGAAGCACGAGGACCTGTAACGTGGAGGTAGCAGATCTCACAACTGGGGAATTGTCAAAGATGAATTAACAGAGTCCCCCAAATACATTCAGAAACAAATATCTTATAATTGCAGTGACTTGGATCAATCAAATGTGACTGAGGAAACACCTGAAGGTGAAGAACATCATCCAGTGGCAGACACTGAAAATAAGGAGAATGAAGTTGAAGAGGTAAAAGAGGAGGGTCCAAAAGAGATGACTTTGGATGAGTGGAAGGCTATTCAAAATAAGGACTGGGCAAAAGTAGAAAATCTTCTGGGAAGAGCTGAAGCACGCGCTCTTGGCTCGGCGCAGCCCGCTGCAATCCGTGGAGGAATGTGCCGCCGAGCAACCATCATGCCTGGGCAGTTACAGGAAGGCTTCAGCTGCCTGGTCACCAACCGATTCGACCAGTTATTTGACAACTAATCGGACCCCTTCGAGGTGCTGAAGGCAGGAGAGAACAAGAAAAAAGAAGCTGGCGGGGGCGGCGTCTCTGGGGCCAAGAGCGGCAGCTCAGGCTGCGACCCAGACCAACTCCAAGGCGGCAGGCAAATAGCTAGCTGCGCAAGGAGTCCCAGAAAGACAGCAAGAACCCGCTGCCCTCCAGCGTTGGCGTGGTTGACAGGAAAGAGGAGACGCAGCCGTCCATGGTGCTTAAGAAAGAAGGAATAAGG
>NM_001018067.2
CTCTCTCGGCCCGGCCATCTTGTGGGAAGAGCTGAAGCAGGCGCTCTTGGCTCGGCGCGGCCCGCTGCAATCCGTGGAGGAACGCGCCGCCGAGCCACCATCATGCCTGGGCACTTACAGGAAGGCTTCGGCTGCGTGGTCACCAACCGATTCGACCAGTTATTTGACGACGAATCGGACCCCTTCGAGGTGCTGAAGGCAGCAGAGAACAAGAAAAAAGAAGCCGGCGGGGGCGGCGTTGGGGGCCCTGGGGCCAAGAGCGCAGCTCAGGCCGCGGCCCAGACCAACTCCAACGCGGCAGGCAAACAGCTGCGCAAGGAGTCCCAGAAAGACCGCAAGAACCCGCTGCCCCCCAGCGTTGGCGTGGTTGACAAGAAAGAGGAGACGCAGCCGCCCGTGGCGCTTAAGAAAGAAGGAATAAGACGAGTTGGAAGAAGACCTGATCAACAACTTCAGGGTGAAGGGAAAATAATTGATAGAAGACCAGAAAGGCGACCACCTCGTGAACGAAGATTCGAAAAGCCACTTGAAGAAAAGGGTGAAGGAGGCGAATTTTCAGTTGATAGACCGATTATTGACCGACCTATTCGAGGTCGTGGTGGTCTTGGAAGAGGTCGAGGGGGCCGTGGACGTGGAATGGGCCGAGGAGATGGATTTGATTCTCGTGGCAAACGTGAATTTGATAGGCATAGTGGAAGTGATAGATCTTCTTTTTCACATTACAGTGGCCTGAAGCACGAGGACAAACGTGGAGGTAGCGGATCTCACAACTGGGGAACTGTCAAAGACGAATTAACAGAGTCCCCCAAATACATTCAGAAACAAATATCTTATAATTACAGTGACTTGGATCAATCAAATGTGACTGAGGAAACACCTGAAGGTGAAGAACATCATCCAGTGGCAGACACTGAAAATAAGGAGAATGAAGTTGAAGAGGTAAAAGAGGAGGGTCCAAAAGAGATGACTTTGGATGAGTGGAAGGCTATTCAAAATAAGGACCGGGCAAAAGTAGAATTTAATATCCGAAAACCAAATGAAGGTGCTGATGGGCAGTGGAAGAAGGGATTTGTTCTTCATAAATCAAAGAGTGAAGAGGCTCATGCTGAAGATTCGGTTATGGACCATCATTTCCGGAAGCCAGCAAATGATATAACGTCTCAGCTGGAGATCAATTTTGGAGACCTTGGCCGCCCAGGACGTGGCGGCAGGGGAGGACGAGGTGGACGTGGGCGTGGTGGGCGCCCAAACCGTGGCAGCAGGACCGACAAGTCAAGTGCTTCTGCTCCTGATGTGGATGACCCAGAGGCATTCCCAGCTCTGGCTTAACTGGATGCCATAAGACAACCCTGGTTCCTTTGTGAACCCTTCTGTTCAAAGCTTTTGCATGCTTAAGGATTCCAAACGACTAAGAAATTAAAAAAAAAAAGACTGTCATTCATACCATTCACACCTAAAGACTGAATTTTATCTGTTTTAAAAATGAACTTCTCCCGCTACACAGAAGTAACAAATATGGTAGTCAGTTTTGTATTTAGAAATGTATTGGTAGCAGGGATGTTTTCATAATTTTCAGAGATTATGCATTCTTCATGAATACTTTTGTATTGCTGCTTGCAAATATGCATTTCCAAACTTGAAATATAGGTGTGAACAGTGTGTACCAGTTTAAAGCTTTCACTTCATTTGTGTTTTTTAATTAAGGATTTAGAAGTTCCCCCAATTACAAACTGGTTTTAAATATTGGACATACTGGTTTTAATACCTGCTTTGCATATTCACACATGGTCAACTGGGACATGTTAAACTTTGATTTGTCAAATTTTATGCTGTGTGGAATACTAACTATATGTATTTTAACTTAGTTTTAATATTTTCATTTTTGGGGAAAAATCTTTTTTCACTTCTCATGATAGCTGTTATATATATATGCTAAATCTTTATATACAGAAATATCAGTACTTGAACAAATTCAAAGCACATTTGGTTTATTAACCCTTGCTCCTTGCATGGCTCATTAGGTTCAAATTATAACTGATTTACATTTTCAGCTATATTTACTTTTTAAATGCTTGAGTTTCCCATTTTAAAATCTAAACTAGACATCTTAATTGGTGAAAGTTGTTTAAACTACTTATTGTTGGTAGGCACATCGTGTCAAGTGAAGTAGTTTTATAGGTATGGGTTTTTTCTCCCCCTTCACCAGGGTGGGTGGAATAAGTTGATTTGGCCAATGTGTAATATTTAAACTGTTCTGTAAAATAAGTGTCTGGCCATTTGGTATGATTTCTGTGTGTGAAAGGTCCCAAAATCAAAATGGTACATCCATAATCAGCCACCATTTAACCCTTCCTTGTTCTAAAACAAAAACCAAAGGGCGCTGGTTGGTAGGGTGAGGTGGGGGAGTATTTTAATTTTTGGAATTTGGGAAGCAGACAGCTTTACTTTGTAAGGTTGGAACAGCAGCACTATACATGAAATATAAACCAAAAACCTTTACTGTTTCTAAATTTCCTAGATTGCTATTATTTGGTTGTAAGTTGAGTATTCCACAGAAAGTGGTAATTATCTCTTCTCTCTTCCTCCATTAGAAAATTAGGTAAATAATGGATTCCTATAATGGGAGCATCACCACTTATTAAAACACACATAGAATGATGAATTAAAAAAGTTTTCTAGGATTGTCTTTTATTCTGCCACATTTATTGATAAACAGTGAAGGAATTTTTAAAAAATTTTTAAGAATTGTTTGTCACGTCATTTTTAGAAATGTTCTACCTGTATATGGTAATGTCCAGTTTTAAAAATATTGGACATCTTCAATCTTAAACATTTCTATTTAGCTGATTGGTTCTCACATATACTTCTAAAAGAAACTTTTATGTTATAAGAGTTACTTTTTGGATAAGATTTATTAATCTCAGTTACCTACTATTCTGACATTTTAGGAAGGAGGTAATTGTTTTTAATGATGGATAAACTTGTGCTGGTGTTTTGGATCTTATGATGCTGAGCATGTTCTGCACTGGTGCTAATGTCTAATATAATTTTATATTTACACACATACGTGCTACCCAGAGATTAATTTAGTCCATATGAACTATTGACCCATTGTTCATTGAGACAGCAACATACGCACTCCTAAATCAGTGTGTTTAGACTTTTCAAGTATCTAACTCATTTCCAAACATGTACCATGTTTTATAAACCTCTTGATTTCCAGCAACATACTATAGAAAACACCTGCTACTCAAAACACAACTTCTCAGTGTCATCCATTGCTGTCGTGAGAGACAACATAGCAATATCTGGTATGTTGCAAGCTTTCAAGATAGCCTGAACTTAAAAAGTTGGTGCATTAGTTGTATCTGATGGATATAAATTTGCCTCCTAGTTCACTTTGTGTCAAGAGCTAAAACTGTGAACCTAACTTTCTCTTATTGGTGGGTAATAACTGAAAATAAAGATTTATTTTCATGCTCACTTCTTAAAAGTCATAAAAACAATCAAATAGGATCATGTTTATTGTCATGTGTTTCCTGGTTTCTGACCTGTGTGCACACCCCTGTGTGTTTATAATTTTTAAATTGAATTTTATATGGGGTTTTTATTTGCTAAAAACCAGGCTGTTGAATCACATTTGGGAAGGGTACTTATCTTAATGACTAATGACTTAATTGGGAAAGTTGAATTCTTGTAAAATACAAAATCCAAGGACTTCTTGGATTTAATCTGATTGTCACTTCTTAGCAGATCACTTTTTTGATAATGAAAGTTAAGCATACTGAATGCTACTTTTGATTGACAAACTGGCTATAATAGTCTAGGGGAAAAATCCCTAAACAGATAAAGATTCCTAAAGTAATGGTGGCAGCTGATGTTTCAGTGAACTTTTATCTTGATGCGTTTAAATGGAAGTAATGCCAGACCTGAGATTTTTAAGGCATTTTTACAGCTTGTATTGAAATGATTGGAGACATGGTTTCTTTATTAGCTATTTTGAGACCTGTGGAGTTAAGCAAGACTTTTAAAAATTGGCACCATATACATCTAGTTAGTTCCTTTACTCTTATTTTTTTAAATAAAAGTAGTACACATCATTTCCAGGGTTGTAAATATATTTGGGGCTTGTTTTTGGTATGGATTTAAAAGGAGGATATTAAGTATTCATTCTAATTTTGTTATTTTTCTAGTTGCCAGAGATGGTTGCACTGAAATAGAACAGGGAGTTGCATACAAAGCCTAAATGTGTATTGGATTTCGAAAATACTAGGTTGGTGCAATTGGTTTTGTACCAACCTAACATGTCTTTAGGAAAGTACCATCATGTGGAAGGAAACAACAGGTGTTAAAAGGTTCAAAGGAATGAGAAATAGGAAGTTACTAGAACCTAACTGATGTTGACCTTAGAGGTAAGATTATTCAGGTATATTAGTGGACCTCCAGTCCAATGGTATAGCAAATTCCAGGGATCTCAGGTGCATGCAATTTTACTTTCTAAAGTAAACACTTAGAAAATAGATTATAACCCAGACGTTTTGGATTATACTGAGACAAATATGTAAATAAGTTTTAGCAAGTCTGAACATGTACCAGCGAGATCTTCAGGTTAACTAAGAAAAGCCCAGAAACTTCATTATTTACTGTGCTTTGTATGGCATAACTGGTAACAAGGCAGTAAAATGATACATATTTGAACTGGACCATAGTAATTAAATGATTTATCAATATCATTTGCAAGATAATTGTCAGGTTGAGTTAATAGTAAGTGGCAGCTTCCCAGAAATTTGGGTTATTTGGCCTAAGCTGTGCCCTGGGATTACCTCTTCATCTTCCTTGACTTTTAAGTTCAAATTTGGAGGTTATGTGAAGTGATTGAAATAAATCTTTCAGGCTGAGGAAGTCGGTAATTTCAAGAATATAGTGAAAACAAGGTTGTAATCTAAACATGAGAAGCTTAAGTTTAGGAAATGGTTAGAATATAAATTGCTAAAGCCATCATGATTTTGGCCACAGATGAAAATATGAACACTGGAAATGAGCGCCATTTAAATGAGATGCTGTATGTAAGCcaggggtcagcaaagttcagcctgtgacctggtgtgtgtgggggtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtccgtgtccctgagttaagaatggtttttaggcttgtataggattaaaaaaaaaaaaaacccacagaaaaatgtaggcagcccagcataagataccgcctttcacagaaatgtttgctgaccccGGAACTGTCACTCTCGGGTTACAAGAGtttgtttctttgaaacagtctggctctgtcacccaggctggagtgcagtggcatgatctcaggtcactgcagcctccacctcccgggttcaagcaattctgcctcagcctcctgagtagctgggattacaggtgtgcaccaccacagacagctaattttACAGGTGTACACCACCACACCCAagaatcacttgaacccgggaggtgggggttgcagtgagccaagatcatagcactgtactccagtctgggtgacacactgtctgaaaaataaaaGTTTAGTTCTAGGTACAAATTAAGTGGTCTACCCAACAGGAAGCTGTGAAATTAGAAGTAATTTTAAAGCATACTTTACACCTCTATATAATCAAAGTAAGGGCAAGATAAAACTTGTTAGTAAAACATGTTTTATTATTTTTTAGATAGGTAGCCTGCAACATAAAATATATTTTGAAAGCTGTTAAGGGGTGTATAATCTGTTAAAAAATACCATGATTAGTATTTCACATTTAGTGACTCAGATCCCTTTGTGTAAGTCCTTTGCGTTGTGCAAAGAGGTTTTTCTATGAGATGAGAATTATGAACACTTCATATAGGTAAATTCCATAGGTTGAGCTGGGGCAGAAATTAATGGCTCCTGGAGATTGCATCtttttttttttttttttGAGCTTAGAATTCCCATTTGGACAGAATTTAGCTTTTGTGCTGTTGATTACTTCTGTACTAAACTGGTAGCCAATTGTTCACTTCTAAATGGAAGGGAAAAAGTTACCCACACAAGTTAGAAAATGATTTACCGAATTATTTTTTTGAGTTAGTATGTATATACTGTTTTAAATCAGTAATGTTTGTTCCTTTTGCTGCCCATTTGGGAGTATGTGGCAATTCCTAGTGCTCTTGTATGACATTACTCTTCTTGAGACTTGTATATGCAAGAAAGTATATATAAAAGATGCCTGGTGGTAACTTTGTATCTGAGTTCTGATTCATTATGGACTTTTAGAAATCTATTTAGATAATTGGTTCATACTAGGTGCTCAATTACTCTGACCTTGTGTGGCTTAATCCTTAAATAGTTGCTTTAGGTGTTACTGGGTGGAAGCATGGAAAGTGAAGGGCTAATATTAAGGATTTTTATGTATTACTGAGTAGGGAAAGTGGGAAGTAGCTTATCTTTGGACAGTTGTATTACTTTGCACTAATCACCTTGTTTGCAGTTGTAGCTGATTCAGTTCTAGATTTTAGGACCAAAAAGATCTCTAATTTAAAGAAACAGTTTTTATATACCTAGAATGAAGATTCTGTTTAAAGCGGTTTTGGTTAACTTGGTTCTTGACATTTGCCTAAAATTTTGTTGGATTGGGACTAAAATGTTCTATTAGCCAATGAATAACGTCCAAGTAAATTTTTGTTTTATTTTGGGAA

Publications

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