Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PRELID3BP4
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr20). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:42897315-42897860  UCSC
Coordinates (T2T) chr5:43150266-43150811  UCSC
Coordinates (hg19) chr5:42897417-42897962  UCSC
Strand -
Parental Sequence NM_016045.3
Parental seq. overlap 467 bp
Parental seq. overlap (%) 18.6%
Genomic Region Intergenic
Retrocopy Summary PRELID3BP4, located on chr5:42897315-42897860, is a retrocopy of the parental gene PRELID3B. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PRELID3B
Full Name PRELI domain containing 3B
Also known as C20orf45|SLMO2|dJ543J19.5
Coordinate chr20:59033145-59042786
Strand -
Gene summary Predicted to enable phosphatidic acid transfer activity. Predicted to be involved in phospholipid transport. Predicted to be active in mitochondrial intermembrane space. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PRELID3BP2
Bonobo Pan paniscus PRELID3BP2
Gorilla Gorilla gorilla PRELID3BP6
Orangutan Pongo abelii PRELID3BP2
Gibbon Nomascus leucogenys PRELID3BP2
Green monkey Chlorocebus sabaeus SLMO2P1
Crab-eating macaque Macaca fascicularis PRELID3BP4
Rhesus Macaca mulatta PRELID3BP4
Baboon Papio anubis PRELID3BP4
Golden snub-nosed monkey Rhinopithecus roxellana PRELID3BP2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PRELID3BP4
GACATCTCTAAGGCTGCCTGCTCCATCATAATCTGGACTTCAGAGCATGACTTTGACCACTCATAGGAAACTGTTACAACAATTGGAATGCACAAATGCCCAAACCCTATGAACATGAGCATGGCTGGGGTTGGTGTACTGGACAGACATAGATCCCTCTGGAGAGTTGCACAACCACAGACTTCTCCACCAAGAGTAGGAACTGCCTTCCATTGTGAAGTCTCTTATTGGTACAGCAAGAACCAAAACATGTACTAGAATATTCTGTAGTTAATCCTATAGAGAAAACAATGGAACTTAAATCTACGAATATTTCATTTACAAATATGGTTTTAGTAGATGAGAGATATACACAAACCACATCATCAGGACACAGAAAAAAACTAGTTTGCCTCAAGAAGCTGTAAGTAGTGAAAGGAAGGAGCCTCAGCAGATACCTTGAAAAAACCGGTGGCAAGAACAGTATCTTCAAATGCTAATAAAGGCTGAGAAGCACTGGAATGGGTCATACATAAATTACATGTTAATATTGAAGAATTGACAGCT
>NM_016045.3
CTCTGTGCCTCGTTGTCCCCTGGCGCTACCCGGACATCTCTCAGGGTGCCGGCACCATGAAGATCTGGACTTCGGAGCACGTCTTTGACCACCCGTGGGAAACTGTTACAACAGCTGCAATGCAGAAATACCCAAACCCTATGAACCCAAGTGTGGTTGGAGTTGATGTGTTGGACAGACATATAGATCCCTCTGGAAAGTTGCACAGCCACAGACTTCTCAGCACAGAGTGGGGACTGCCTTCCATTGTGAAGTCTCTTATTGGTGCAGCAAGAACGAAAACATATGTGCAAGAACATTCTGTAGTTGATCCTGTAGAGAAAACAATGGAACTTAAATCTACTAATATTTCATTTACAAACATGGTTTCAGTAGATGAGAGACTTATATACAAACCACATCCTCAGGATCCAGAAAAAACTGTTTTGACACAAGAAGCCATAATTACCGTGAAAGGAGTTAGCCTCAGCAGTTACCTTGAAGGACTGATGGCAAGTACGATATCCTCAAATGCTAGTAAAGGCCGAGAAGCAATGGAATGGGTAATACATAAATTAAATGCTGAGATTGAAGAACTGACAGCCTCAGCAAGAGGAACCATAAGGACTCCAATGGCAGCAGCAGCGTTTGCAGAGAAGTGATCGTGACAGTTGGTAGACAACATCGGGTACTCCAGGTCTCTCCAAACTGACTATATATTTATTTGTTATTTTAAAAATACAACTATATTTTGGGTAGtttttttttttttttttttGATAAGTTGGTGTAAGGCTATGTGACTTGATCAAAACAGATGCAGGGCCTCTAAATAAAAGGGATCATCTGAAATTAATGTTGTTTGAAATTACTATCTGATTTTGAGGGTTCCAGTATTTCTGTGAAAATTCAACAAGAACTCCTTGGAAACTGGTATTGATATTCAGTCTCCTTAAGGTAGATTTTTCAAGCTTTTCATACATTGGAACTCCACCTGACTTTGGACCAACCCCAGAACAGAGCAGAGCCACCTCCTATAGACGCCCATTGCCCTGCTGCTGTACACTTCAGCAGCTTGCACAAGGGAGCTCACTTAAAAGGAGAAATTGTGTAGTTTTAAAATATATTTTGTGTAAAATACCTTACTATGCTATAAACCACCATTAAAAACCAGTGTTTTGATTTGGTACTTAAATATTTTTGGAGTGAAAATTATCACTAAAGTAACATGACTCCAACAAAAGTATGGTTTCATTATAAAAGAGTACTGTATTGATTTGCCCAAGTTTTGTAACTTAGTAAAGGTATTAACTTCCTTGGATTTGTACTTTGTGATTTAGTATGCTGTATCGTGGGCTGGTTATGTTAACTGAAAAAAATAAAGTCATTACCTGAGTTTTGCAGTGCTCTAACTTAAACAGAAGAACAGCTGTTCACATCTTTTAGCATTTTACATTTGCCTAACTTAAAAATTGCCATGTGTCAAAATCATGGTTTTGTAATTGCTAAGGCATGATATGTCAGGTTATTTGAATATAATTACTTTTTGAAGTAATTGTGACCACAAAACATCTTTTTTACATGAAGGAGCTGTGTATCATTTGAAATTACTCAAATGATGTCTTGCTCTGAGGCATAAATCCCAGGTACTTAGTGTTTTTAATAATATGGTGCCACTGCAGGATTTGGGGGCGGTGGGGAAGAACAAGCATAATGGTAGGGGGAGGCTTGGCCTGAAACTAACCACTGAGTGAATTGCACTGCAGGTTTTACTTAACGGGAATTCCTTATTTGGGATGTCAAGAGGGCAGCTGCAAACTGAAAAACAATCCAGTAAATGTACTTTGTTTTATGTATTGTAGCAGGCAATTAACTACTAAATAATAGCTTTGACATTTGCAATTGTTGCATAGAGACTATTTTTGCTAGAAGATGATTAGCTCTTGCCTTTATTTTACAGTGCTTAGTGTGATAAACTTCTAGTCATGTTTCCTATCCAAGAGACCAGTTAATATATGTACATAAACCACAGAAATAGTATAACACACTATTTTTAAATTATCGTTTTCCTACTTAAATTTTGTTTAGCTTAAGACTTCTTAGGACATTTGTAAAAGCAGGTTAAATTTAATAAGGTTTCTGATTTTTTTTTGTAACCGGAGATAGTTTTTACAAGTGAAATAACATTTCAGCTAAATAAAACATCGCTAAATAATTGATATTTGATGAAAATCTGCTTTGTATAATTTCTGTAAATTATCCTTGTTCTGAAAAAGGTGTAATGCCCTAATATTTTTAAATCCTTATCCTTTGATTTTTTAAAAACTGACCTATTGATAAAACTATAAATTTTCATTTTCCAGTGCAGTTAGTTACCTTTTTAAACATAAATGCACAACAAGCAAATGAATTTAAGAGAACTAAACTGGAATAAGTGTTCATAAATGAAACCCTTGGACTATTTAATAAAGTTGAAATGTGAATTAAGGAAAACTTTTGTTAATAAAAACTTTCTTTTAAGTGA

Publications

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