Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name KATNBL1P4
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:51930797-51932406  UCSC
Coordinates (T2T) chr5:52752655-52754270  UCSC
Coordinates (hg19) chr5:51226631-51228240  UCSC
Strand +
Parental Sequence NM_024713.3
Parental seq. overlap 1108 bp
Parental seq. overlap (%) 40%
Genomic Region Intergenic
Retrocopy Summary KATNBL1P4, located on chr5:51930797-51932406, is a retrocopy of the parental gene KATNBL1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name KATNBL1
Full Name katanin regulatory subunit B1 like 1
Also known as C15orf29
Coordinate chr15:34140674-34210096
Strand -
Gene summary Predicted to enable microtubule binding activity. Involved in positive regulation of cytoskeleton organization. Located in several cellular components, including cleavage furrow; mitotic spindle pole; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Bonobo Pan paniscus KATNBL1P2
Gorilla Gorilla gorilla KATNBL1P2
Orangutan Pongo abelii KATNBL1P1
Gibbon Nomascus leucogenys KATNBL1P1
Green monkey Chlorocebus sabaeus KATNBL1P1
Crab-eating macaque Macaca fascicularis KATNBL1P2
Rhesus Macaca mulatta KATNBL1P2
Baboon Papio anubis KATNBL1P2
Golden snub-nosed monkey Rhinopithecus roxellana KATNBL1P1
Chimpanzee Pan troglodytes Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>KATNBL1P4
TTTAAGAGATGATGGCATCTGAAACCCACAATGTTAAAAAGCAGAACTTTTGAAATAATATTCAGGATCATTTAATTGATGGACCTAGGAAAAGGATTTCTAATTTCATTAATAAGAACAAGAAGGAAGTTAAGAAACCTCAACAGTTAGCTGCTTATATAAATAGAACAGTTGGACGAACTGTCAAAAGTCCAGATAAAACTAGGTAAGGTAATCTCTATGTAAGGTAATCTTTCATAGAAAGTTAGTTCATTATCCCTTTCCAAACCTCTGTTATAGGAaGTCCCCTAGAAGTGGGGCTGTGACGTGGCAAATAAAGAAAATGAACTGGTTTGTGCAGGCCACCTGCCTGAAAAATTATGCCAGAGTAGGCAAATATATTTGCTTAACCCCAGTGATTCCAATTTTTCACAGATATAAAGCCCATCATCACAATACAGTCAGTATTTTTCGCAAGTTTCTCAGGATCATGAAACAAATGGCCCAAGTTTTGCTCAGCAGGAATTTGAAACTGAATGTATCTTTAACTTTCTGGAGAAAGAAGTATACGTGAATTTGCAGCTTGTTTGGTGAGAATAGAAGATCTTGGCATTGAGGTAGATTGCCTTCCTGTGCTCACCAGTAGTTTACAGGGAGAAAAACAATATATCTTACTTGAACGCTGGGTAGGCTCGTTGCCTCTAGTAAACTCACTATGTAAAAGCAAATTTGAAAAATACCTAACAGTTGGTTTAAACTGGCTTCAAGCAGTCATTAAAAGGTGGTGGTCAGAACTATTGTCCAAAACAGAAATTATAAATAATGGAAACATTCAGATTTTAAAACAACAGTTAAATGGATTGTTAGAACAGGAAAACCACCTTACTTTGGTTCCAGGATATACTGGTAATATAGCTAAGGAAGTAGATGCTTATTTATTACCAGTGAGAGATTTAATCTACTAAAGAGCATTTGTTTATTCAAAACATTCCTGGATTATACAATTTACAAGAAAAAAAAAAGATTTCTTCCGAGAGCTCTGAACTGTGGAAGAAATTAAAACCATTTTTTCTTTTAAAAAGCCACATAATAAAACCACTAATGAAACCATAACAATCTACTTCACATAGAAGTGAAAAAATACCCAAAAGAAGCAGCTTCAACTTTAATGAGATGAAAGTACACTATGGAAAATGTTGGCCTTGCTGCATTTGGGGTTTATATAGTTATTTGCTAACATTATTTAAGAACTACTGGATCTTAACACAAGCCTGCATAAAAATATACTTTCTATTGTGTGAAAAACTAAGA
>NM_024713.3
AGCTATCCCGGCGGGCCGCGCGCGCGGCCGCGTTTGAATGGCCCTGAGTGGGACTCGGCCCAGAAGCCGAGGGACTCTCTAGGCTGCCGGGCGCTGGTCGTCAGCGCCGAGGCTGGGCTGAGGCGCCGCGGTACCATGAGGCGCCGGTACTTAAGAGATTATGGCATCAGAAACCCACAATGTTAAAAAACGGAACTTTTGTAATAAGATTGAGGATCATTTCATTGATCTTCCTAGAAAAAAGATCTCTAATTTCACTAATAAGAACATGAAGGAGGTTAAGAAATCTCCAAAACAGTTGGCTGCTTACATAAATAGAACAGTTGGACAAACTGTGAAAAGCCCAGATAAACTTCGTAAAGTGATCTATCGCAGAAAGAAAGTTCATCATCCCTTTCCAAATCCTTGTTACAGAAAAAAACAGTCCCCTGGAAGTGGGGGCTGTGACATGGCAAATAAAGAAAATGAACTGGCTTGTGCAGGCCACCTGCCTGAAAAATTACACCATGATAGTCGAACATATTTGGTTAACTCCAGTGATTCTGGTTCTTCACAGACAGAAAGCCCATCATCAAAATATAGTGGGTTTTTTTCTGAGGTTTCTCAGGACCATGAAACAATGGCCCAAGTTTTGTTCAGCAGGAATATGAGATTGAATGTAGCTTTAACTTTCTGGAGAAAGAGAAGTATAAGTGAACTTGTAGCTTATTTGTTGAGGATAGAAGATCTTGGCGTTGTGGTAGATTGCCTTCCTGTGCTCACCAATTGTTTACAGGAAGAAAAACAATATATCTCACTTGGCTGCTGTGTTGACTTGTTGCCTCTAGTAAAGTCACTACTTAAAAGCAAATTTGAAGAATATGTTATAGTTGGTTTAAACTGGCTTCAAGCAGTCATTAAAAGGTGGTGGTCAGAACTATCATCCAAAACAGAAATTATAAATGATGGAAATATTCAAATTTTAAAACAACAATTAAGTGGATTATGGGAACAGGAAAACCATCTTACTTTGGTTCCAGGATATACTGGTAATATAGCTAAGGATGTAGATGCTTATTTATTACAGTTACATTGAGAGATTTCATCTACTAAAGAGCATTTGGTTTTTCAAAACATCCCTGAACTGTATAATTTACAAAAAAAAAAAGTCTCGTCTGAGAACTGTGAACTGTGGAAGAAATCAAAACTATTTTTTCTTTTAAAAAGCCACGTAATGAAACCACTAATGAAATCCCAGCAATCTGCTTCACATTGAAGTGGAAAAATATCCAAAAGGAGCAGCTTCAATTTCATTGAGGTGAAAGTGCACTATGAAGATTGTTCACCTTTGCTGCATTTGGGAGTTATATGGTTATTTGGTAACATTAAGAACTACTGGATTTTAATGCAATCCTGCATAAAAATATAATTTATACTATGTGAAAAAATAAGACAGGACTTACCACTAGGAACCACCAAGACCAATCATCATTAACTTTTTTAAGATTGTGTTTTATTAAAAAAAAAAAACACTTAAATGTGTGCAGCTATTTTCTTATGTTGAAAAGACTGAAAGTTTAAAACATGAAAAAAATCAATATTAAACATTTTTTGTTCACACTGAGATACTGTGTATGTAAAATGCCTTAATTATTAATAAGCCAATGTGTTATGATACCAATATCTGTTTTAAAAAACTAAAACCAACCATGCTTCTGGCATGATAAAATCATGGAATTAAATCAGGGGTTTACATTCTTGTAGAGTGTTCTTGAAACACTCTCTGCACCATTTTTAAAACTTGAGAATAGTTTTAGTATCTCTGATATTTTTTGCCAGAATCATCATGTCATGTATGAATGTGTTATCCCTATCTAAGGAAAAAGGTGAATATGTTTTTGTATGAATGTTTAACTGGAAATGTCCATGGACTTGGCTAATTTATATTTACTTTTTATTGTACATAGATTTCTAATATTTTTCATTCCTGTATCATTTAAACTTCCTTCATTTGAGTAAATTCACTAAAtatttctattttttgcttttttaaattctgattttatatgaattctaattctttttcACTACATATGTTTTAAAGAGTTACATACAGTGATTTAGAATGGTTTACAGTTAATGCTGATCTTGTATTTTAAATTCCAACACTTTGTGTCACTACCTCCTCTAATGGTTAGTATGATATGCTAGCAGACTGTATGAGGTCTTTTTTTAAAATACCACTTTTAGTGTCAGTGAACCAAATTCTGGAATGTCTTAACAGCTCTAAATCTTACTTGTCTTGAAAATGATTGGGGTTTAATACCACTGCTGGTGGTTCACACATCATCCCATCCTTAATATGCCTGACAGGCATCTGAGCAAAGGTTTTTAGTAATTGAATTTCTCTGCAGTAGTCCTTCAAGCACTTGAATGTAAACCTTTAGCATTTATTCGTTTAATGACTACTGATACGAATCTCAAGCAGATTTCTTGCTCTTAAAAGTTATGTTTCACTGAGTTCTGGTTTTGTGTAGCTATATTTTATATAGCTAGATATTCCTCACAGTGAACATGAATTGTAATAATTGGTTATTTCCTTAAGTCTTTAGATTATAATAATTTCAGATTATTGCACGTCTGTGATTTGAGAGGTGAGTTATTTAAGAGGCCAGTTTTCAGGACATGGGAATTTGAATTGTAAACCTGTTATCTCTGTGAAACTTTTAACATGATAAAATATAACCTTTCTTTGTGCTTA

Publications

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