Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name C12orf73P1
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:57364346-57364645  UCSC
Coordinates (T2T) chr5:58193078-58193377  UCSC
Coordinates (hg19) chr5:56660173-56660472  UCSC
Strand -
Parental Sequence NM_001135570.3
Parental seq. overlap 255 bp
Parental seq. overlap (%) 14.9%
Genomic Region Intergenic
Retrocopy Summary C12orf73P1, located on chr5:57364346-57364645, is a retrocopy of the parental gene UQCC6. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name UQCC6
Full Name ubiquinol-cytochrome c reductase complex assembly factor 6
Also known as BR|BRAWNIN|C12orf73
Coordinate chr12:103950194-103965755
Strand -
Gene summary Involved in mitochondrial respiratory chain complex III assembly. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Bonobo Pan paniscus C12H12orf73P1
Gorilla Gorilla gorilla C12H12orf73P2
Orangutan Pongo abelii C12H12orf73P1
Gibbon Nomascus leucogenys C10H12orf73P1
Crab-eating macaque Macaca fascicularis C11H12orf73P2
Rhesus Macaca mulatta C11H12orf73P2
Golden snub-nosed monkey Rhinopithecus roxellana C10H12orf73P1
Chimpanzee Pan troglodytes Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>C12orf73P1
CTGAAAATGCTTGCAGCCAGCCTCCTGGCCATGTGCACAAGGGGCTGAATTGGTAAACAGGTCCCACCCACCAGATCTGATAATACCTGAAATTCCACCAAAGCCTGGAGAACTCAAAATGGAGTTTTGGGGACTGAAAGAGCAACAACAAAACCTCACATTTCTCAGCAGTAGAAACTTAAATAAAACTACCATGAATCTGTAAAGAATAAACCTTAAGTGTGTATTTTTTTAATTTATTGAGTCAAACTACTTGTCCTTAAGCACCTAGTCCAATGCTAGCTGCAAGAGGGGTGCTCG
>NM_001135570.3
GTATTTTGGGTCCGGCCTGCTCGCCGTCCGCTCCGTCCGCCCTTAGACCTGTTGCCCAGCATCCCTGCAGTTCGCGGTACAGTCTCTAGTAGAGCGCGTGTATAGAGGCAGAGAGGAGTGAAGTCCACAGTTCCTCTCCTCCAAGAGCCTGCCGACCATGCCCGCGGGCGTGCCCATGTCCACCTACCTGAAAATGTTCGCAGCCAGTCTCCTGGCCATGTGCGCAGGGGCAGAAGTGGTGCACAGGTACTACCGACCGGACCTGACAATACCTGAAATTCCACCAAAGCGTGGAGAACTCAAAACGGAGCTTTTGGGACTGAAAGAAAGAAAACACAAACCTCAAGTTTCTCAACAGGAGGAACTTAAATAACTATGCCAAGAATTCTGTGAATAATATAAGTCTTAAATATGTATTTCTTAATTTATTGCATCAAACTACTTGTCCTTAAGCACTTAGTCTAATGCTAACTGCAAGAGGAGGTGCTCAGTGGATGTTTAGCCGATACGTTGAAATTTAATTACGGTTTGATTGATATTTCTTGAAAACTGCCAAAGCACATATCATCAAACCATTTCATGAATATGGTTTGGAAGATGTTTAGTCTTGAATATAACGCGAAATAGAATATTTGTAAGTCTACTATATGGGTTGTCTTTATTTCATATAAATTAAGAAATTATTTAAAACTATGAACTAGTTTCATTAATTGAATTTGCTAAGTGGAGTTATTTCTCATTGCTAAACTGTTTTTTTTCAAATTCTAGATCTCTGCTAACTTTAGTAAATGAACACTAAAGTGGTGAGCTTTGATAATGCATTTTGTGGATACAAAATCATCGCCTCATCACTTTCTAGAATGAAAGGCTGGGGGCATTGCTCACCTTTTGCGTGAAGAAAAGACCTGTCCCTTAGAGCCAGTTTTTGCTTAAGGGGAGGACAGACCGTCGTCACCCAGTGGACCACGTGAATGAATGGATGCAGTGCATGCTTTAGAAGCACCGCATACCTCCTTTTACAGGTACAGAGTAAGTGGTCTGGCTACTGAGGGAAAGAGTCATGATTTGAATCCGAGTCTTCTGTAAGACAATGACTTCATGAAGGTGAAAAATCAGTTTTATGGTTATTAAAGTAAAAATTTACCTTGGGTAAAAATGCCATCTTTATTTCATTAAGTACTGGTTCTAAGTGACTTCCAATAAGATACATTTTCTTCCTGTTTTGAAGTTGATCCCCATTGTGAAAAATATACATtgtagtggtcatggaaatgcgccatccatactccctaaggcaggcttgttgccctagtatcaagcatgccagcagctttcaatggtcagcttctagaaggattgcctcggctatggtggccttgctcaaagccatgcctcctgaaggggcccaaatccagtgactgttggaggtgagaatagaaaggcctggccacttcagcacgtgagtggtgggcaactctgctgggcccaccacaactccctatggggtttagggacactgtctttggatctgcattgcaactcaacttatacctctgctcagtcctgtttcctttctcaggtgttgatcgaagggtgtgccttcatagaccccctgctaaactgcacctcagtgtttcttggagaaccaaatctgtaacaTATATGCATTAAAAATTAAAGGCAGTACTATATTATCCCCTAA

Publications

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