RCPedia: Rtcs

Summary

Retrocopy Name	IMPACTP1	Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr18). Each line represents a retrocopy.
Species	Homo sapiens
Coordinates (hg38)	chr5:78999893-79001127 UCSC
Coordinates (T2T)	chr5:79481005-79482239 UCSC
Coordinates (hg19)	chr5:78295716-78296950 UCSC
Strand	-
Parental Sequence	NM_018439.4
Parental seq. overlap	1049 bp
Parental seq. overlap (%)	27.4%
Genomic Region	Intragenic (DMGDH)
Retrocopy Summary	IMPACTP1, located on chr5:78999893-79001127, is a retrocopy of the parental gene IMPACT. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	IMPACT
Full Name	impact RWD domain protein
Also known as	RWDD5
Coordinate	chr18:24426670-24453531
Strand	+
Gene summary	Predicted to enable actin binding activity and ribosome binding activity. Predicted to be involved in several processes, including GCN2-mediated signaling; cellular response to starvation; and negative regulation of nitrogen compound metabolic process. Predicted to be located in cytoplasm. Predicted to be part of polysome. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species	Scientific Name	Retrocopy
Chimpanzee	Pan troglodytes	IMPACTP1
Bonobo	Pan paniscus	IMPACTP1
Gorilla	Gorilla gorilla	IMPACTP1
Orangutan	Pongo abelii	IMPACTP1
Gibbon	Nomascus leucogenys	IMPACTP1
Green monkey	Chlorocebus sabaeus	IMPACTP1
Crab-eating macaque	Macaca fascicularis	IMPACTP1
Rhesus	Macaca mulatta	IMPACTP1
Baboon	Papio anubis	IMPACTP1
Golden snub-nosed monkey	Rhinopithecus roxellana	IMPACTP1
Marmoset	Callithrix jacchus	Without Homology
Mouse lemur	Microcebus murinus	Without Homology
Mouse	Mus musculus	Without Homology
Rat	Rattus norvegicus	Without Homology
Chinese hamster	Cricetulus griseus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Dolphin	Tursiops truncatus	Without Homology
Horse	Equus caballus	Without Homology
Dog	Canis familiaris	Without Homology
Panda	Ailuropoda melanoleuca	Without Homology
Cat	Felis catus	Without Homology
Pale spear-nosed bat	Phyllostomus discolor	Without Homology
Velvety free-tailed bat	Molossus molossus	Without Homology
Greater mouse-eared bat	Myotis myotis	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
Egyptian rousette	Rousettus aegyptiacus	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>IMPACTP1
GGGCTACATGGCTGAGGGGGACGCAGGGAGTAACCAAAGGCAGGATGAGGAAATTGAAGCAATGGTAGCCATTGATGGCGAGGAATGGTGTGTCATTGATGACTGTGCCAAAATATTTTGTATTAGAATTAGCTACGATATAGATGACCCCAAATGGACACTTTGCTTGCAAGTGATGCTGCCAAATGAGGACCCAGGTACAGCTCCACCTGTCTATCAGTTGAATGCTCATTGGCTTAAAGGGCAAGAACTTGTCCATTTATTGAATAGCCTGAGGAAATATATATGTGGCCACCCCATCTGGTTCGGTGAGAGTACCTGCTTTGTGTCCCTGGGATCCAGGCTAAGTTTCTTTTCCTCCCAAAATATTTAATGAGAAAATGACAGAATATTGGTGAAAGTATTCTTTACCTGTGAGTGGAGAAAATAAGAGATGTTCCAATACAAAAACCTCAGATGACAGAACCAGGCCCAGAGGCAAAGAAAGAAACTGAAGAGGAAGATGTTGAATGTGAAGATGATCTCATTTTTGCATGTCAGCCAGAAAGTTCGGTGACAGCACTGGATTTTGATATCAGTGAAAATCAAAGAGAAATAGAATTATCTCTGATTGATCATGGCATTTCTGTTACAGACCGAATAAGTACTTTTCAGGCAGACTTTGATCCAGTAGTTTGTCCCAAACAGGTGAAAATGGTTCTTTCCAACTTGTATGAGAATAAGAAAATAGCTAGTACCACCCACAGCATCTATGCCTACAGAGTATATTGTGAGAATAAACAGACCTTCTTACAGGATTGTGAGGATGATGGGGAAAGAGCAGCTGGTGGGCATCTTCTTCATCTCATGGAGATTTTAAATGTGAGGAATATCATGGTGGTGGTATCACGCTGGTATGGAGGGATTCTGTAGGACCAGATCACTTTAAACATAACTGTGCCAGAAACATACTAGTGGAGAAGAACAACACACATTCACCTGAAAATCATCTAAGGCTTTGGAAAAAAAACAAAAAATGTTCATCACTGAGTAATGGAGTAAGTGAAAATCCAGGAGTATCCACTTGCAGTTATGGGCTGAGGTGACAATTCTTCCAACATATTTGTTAGCGTAAATATTATGCCTCCATTTCTGTTGCAAATTGGTGATTGTGAAATTTCCAAAAGTGATTTTCTAGTCTCTGCTTCTTTAATTCTTATAATATAAAGCAATAAATATGGAGTGTCAGTAGTCTT

>NM_018439.4
agccagctctcggctcgcagccgcagcgccccgcccccgcgcTCCGGACCTGGCAGGCGGCGGCTGCAGGGCAGGTCCAGGGGCCACATGGCTGAGGGGGACGCAGGGAGCGACCAGAGGCAGAATGAGGAAATTGAAGCAATGGCAGCCATTTATGGCGAGGAGTGGTGTGTCATTGATGACTGTGCCAAAATATTTTGTATTAGAATTAGCGACGATATAGATGACCCCAAATGGACACTTTGCTTGCAGGTGATGCTGCCGAATGAATACCCAGGTACAGCTCCACCTATCTACCAGTTGAATGCTCCTTGGCTTAAAGGGCAAGAACGTGCGGATTTATCAAATAGCCTTGAGGAAATATATATTCAGAATATCGGTGAAAGTATTCTTTACCTGTGGGTGGAGAAAATAAGAGATGTTCTTATACAAAAATCTCAGATGACAGAACCAGGCCCAGATGTAAAGAAGAAAACTGAAGAGGAAGATGTTGAATGTGAAGATGATCTCATTTTAGCATGTCAGCCGGAAAGTTCGCTTAAAGCATTGGATTTTGATATCAGTGAAACTCGGACAGAAGTAGAAGTAGAAGAATTACCTCCGATTGATCATGGCATTCCTATTACAGACCGAAGAAGTACTTTTCAGGCACACTTGGCTCCAGTGGTTTGTCCCAAACAGGTGAAAATGGTTCTTTCCAAATTGTATGAGAATAAGAAAATAGCTAGTGCCACCCACAACATCTATGCCTACAGAATATATTGTGAGGATAAACAGACCTTCTTACAGGATTGTGAGGATGATGGGGAAACAGCAGCTGGTGGGCGTCTTCTTCATCTCATGGAGATTTTGAATGTGAAGAATGTCATGGTGGTAGTATCACGCTGGTATGGAGGGATTCTGCTAGGACCAGATCGCTTTAAACATATCAACAACTGTGCCAGAAACATACTAGTGGAAAAGAACTACACAAATTCACCTGAGGAGTCATCTAAGGCTTTGGGaaagaacaaaaaagtaagaaaagacaagaagaggaatgaaCATTAATACCTGAAACTATAGGAAAGGTTAATTTGCCTATAATTATATATACATTCCATAGTCATCAAGGAATATATTGTGCAGAGAGAGTATCCTTGACTGCTTAAGTCAGCCAGTTCAGCATGGATACCAACATTAGCTTTTCTTCTTGGTTATATCATCTGCCAAAAATAGAGAACTTATGATCTATTCATGTGTGTTTCAGGCTTATTTGGGAGAACTAATTTGAACTTAATCACCACTTCATCTAATTTTAGCAAGGTAACAGTTGCCCAGGGCAGTACCTGAATTAACTGTCCATTTCAGTACATGTCAAGTGCCTTTGTTAGGTGGAGAAGAAATGTCTCTAGAGGAATATAAATACCTGATTTCTTGTCATCGAGATTCTTGTACTGTTAAATGAATATTGCCTTTTACTGCTCTTTATGGCTTATTGGAATAGGAGCTCATTTAAGATTGATCTTGGAGAGTTTCTTCTTGTGATTTTAGTTCATAAGTATGTCACCTTTCATTTTATAGTGTTCATCATTGAGTAATGGATTAAGTGAAAATCCAGGAGTATCCATCTGCAGTTATGTGCTGAGGTGATAATTCATCCAACATATTTGTTAGCATAAATATTATGCTTCAGTTTCTGTTGCAAATTGGTGATTGTGAAATTACAGAAAGTGATTTTCTAGTCTGCTTTTTTTGTTTAATTCTTGTAATGTAAGCAATAAATATGGAGTGTCAGTAGTCTCCTTCCACCCCAGAAATGTGTTGGTGTAACATTCTCGTTTCTTTTAACAACCTGGAAGTACCTTTCTTGTGATCTTCACTGAGGAATTAGAACTATGATAGAAGTTAGGCTGTGGCAAATGGGACATTCGTAGAGTGGGATAGAGGTGGCAGAATGAACCTGGTGTAGGGCAGGAGTATGTTGTGTAGTTACATCAATTTGATGCATGCTTTCCATCTGCACTCCAGACGGCTTTCTCAGTTCCAAGATTTTGCAGAGAGAAGGAGCAAACCTTTTCATTGGAAAAACAGAAACAACCCTCCCCCCCATTTTTTCCCCTCTATTCATCAAACCTTTATGTATCTTTCATCTTCCAGTTACCTCTAGGCATTTAGATAGTGAAATTTACCTTTGAGATATAACAATAAGTGATTAACTGTTCACTTTCAGATGTAATGGCAAACAATTGTTAAAAGTTATTAACTGATCACAGATTTGCCTGGACTTCCCTTCCCAGGGAGGGAACAGAAGTTAGGAGGCAACTTTGGGATGGTGCTAGAGCATGGAAAGCACAGAGAATTGGACAAACAGGTCTTTTTCTCTTTTCTCTGATGTTTTACCTTTAAAAGATCCAACATCCTTACCGTTGGTATTTTTAGTAAGGTTATAGTAAATAGCTTTACACCAGGATGGattctgaaatataaattctaaattatatttgttataactatattttatgttgtatgttATCAGGAGCCATCAGAGAATGACCTTTTTGTGTTTGGAACACTTGGTTCCATGAAAAGTATGCTTTGTGTTTTAACTGTTAAAATAATTTAAAAATTAATTATTTTACATAATTAAAGAAGTTAAAAACTATTAACATTAAATAATTTCACAATTTCAACATGTCAAACCTATGAAGGGAGATAGGAAACAATGAGAAACTTACTTTTGCTCCTTTATACAGAATTATTAACTATATTTTACTAACTAAAAAACTCTAGTATTCTTTACCTAAAGTCAATTGGCTGGTAAGAGGGAGAGATGCAAAATTCTCCAGCTCTGAACTTGGAGCTACTTCACACTCTACTCTTAATGGAAACTTGAACTAATGATAGATAGTATTTTTTTCCTCTATTTAAAATTTTTGTCTTGATTAGGAGATTTTTCAGTTCTCCATATAATAATTTTCTACAATCAGATCTATGCTGTGGCATATTTTGCTTTATTTAAAAAtttttttttagagatgagttcttgctctgtcacctaggctggagtgcagtggcatgatcatggctcactgcagccttgaccttccagcctgccaagtagctgggattacagacaggcatgtgctattacacctggctaatttttaaagttttttttgtaaagatagggtctttctatgttgcccaggctcgtcttgagctcctggcctcaatcgatcttcctgccaaggttttggaattacaggtgtgagccaccatgcctggccTGCTTTGACATATTTTATAGTGTGTTAATTACAAATAGTCTTCATATGCCAGAATATAAGAGCAAGTGTTATCTACTTTTTAGATGGGAATTGCAGAAGCTGCATCAAAAGTATGCTTTGAGGTATATATAGTGAAACAGAGCCTTTCTGAAGAGAATTATATCAAACTAATTACAACCAAGAAATAATAGTATGAAGCGGATGCTGTTTGGAGGACAGGAAAATTTATCGGGAAAATTACATaatccctctgattccactatccagagatagccattattattaatatttggtatgtacatccttatattatttttttcttatgcatgattttgtatatatggttatttttctttccataaaaatggtattaaactgtatatactgttttgtagcctacatatttcatatagaagtatattgttaacattttccatgtcaataaatattcttctatggcttaaa

>NM_018439.4 

agccagctctcggctcgcagccgcagcgccccgcccccgcgcTCCGGACCTGGCAGGCGGCGGCTGCAGGGCAGGTCCAGGGGCCACATGGCTGAGGGGGACGCAGGGAGCGACCAGAGGCAGAATGAGGAAATTGAAGCAATGGCAGCCATTTATGGCGAGGAGTGGTGTGTCATTGATGACTGTGCCAAAATATTTTGTATTAGAATTAGCGACGATATAGATGACCCCAAATGGACACTTTGCTTGCAGGTGATGCTGCCGAATGAATACCCAGGTACAGCTCCACCTATCTACCAGTTGAATGCTCCTTGGCTTAAAGGGCAAGAACGTGCGGATTTATCAAATAGCCTTGAGGAAATATATATTCAGAATATCGGTGAAAGTATTCTTTACCTGTGGGTGGAGAAAATAAGAGATGTTCTTATACAAAAATCTCAGATGACAGAACCAGGCCCAGATGTAAAGAAGAAAACTGAAGAGGAAGATGTTGAATGTGAAGATGATCTCATTTTAGCATGTCAGCCGGAAAGTTCGCTTAAAGCATTGGATTTTGATATCAGTGAAACTCGGACAGAAGTAGAAGTAGAAGAATTACCTCCGATTGATCATGGCATTCCTATTACAGACCGAAGAAGTACTTTTCAGGCACACTTGGCTCCAGTGGTTTGTCCCAAACAGGTGAAAATGGTTCTTTCCAAATTGTATGAGAATAAGAAAATAGCTAGTGCCACCCACAACATCTATGCCTACAGAATATATTGTGAGGATAAACAGACCTTCTTACAGGATTGTGAGGATGATGGGGAAACAGCAGCTGGTGGGCGTCTTCTTCATCTCATGGAGATTTTGAATGTGAAGAATGTCATGGTGGTAGTATCACGCTGGTATGGAGGGATTCTGCTAGGACCAGATCGCTTTAAACATATCAACAACTGTGCCAGAAACATACTAGTGGAAAAGAACTACACAAATTCACCTGAGGAGTCATCTAAGGCTTTGGGaaagaacaaaaaagtaagaaaagacaagaagaggaatgaaCATTAATACCTGAAACTATAGGAAAGGTTAATTTGCCTATAATTATATATACATTCCATAGTCATCAAGGAATATATTGTGCAGAGAGAGTATCCTTGACTGCTTAAGTCAGCCAGTTCAGCATGGATACCAACATTAGCTTTTCTTCTTGGTTATATCATCTGCCAAAAATAGAGAACTTATGATCTATTCATGTGTGTTTCAGGCTTATTTGGGAGAACTAATTTGAACTTAATCACCACTTCATCTAATTTTAGCAAGGTAACAGTTGCCCAGGGCAGTACCTGAATTAACTGTCCATTTCAGTACATGTCAAGTGCCTTTGTTAGGTGGAGAAGAAATGTCTCTAGAGGAATATAAATACCTGATTTCTTGTCATCGAGATTCTTGTACTGTTAAATGAATATTGCCTTTTACTGCTCTTTATGGCTTATTGGAATAGGAGCTCATTTAAGATTGATCTTGGAGAGTTTCTTCTTGTGATTTTAGTTCATAAGTATGTCACCTTTCATTTTATAGTGTTCATCATTGAGTAATGGATTAAGTGAAAATCCAGGAGTATCCATCTGCAGTTATGTGCTGAGGTGATAATTCATCCAACATATTTGTTAGCATAAATATTATGCTTCAGTTTCTGTTGCAAATTGGTGATTGTGAAATTACAGAAAGTGATTTTCTAGTCTGCTTTTTTTGTTTAATTCTTGTAATGTAAGCAATAAATATGGAGTGTCAGTAGTCTCCTTCCACCCCAGAAATGTGTTGGTGTAACATTCTCGTTTCTTTTAACAACCTGGAAGTACCTTTCTTGTGATCTTCACTGAGGAATTAGAACTATGATAGAAGTTAGGCTGTGGCAAATGGGACATTCGTAGAGTGGGATAGAGGTGGCAGAATGAACCTGGTGTAGGGCAGGAGTATGTTGTGTAGTTACATCAATTTGATGCATGCTTTCCATCTGCACTCCAGACGGCTTTCTCAGTTCCAAGATTTTGCAGAGAGAAGGAGCAAACCTTTTCATTGGAAAAACAGAAACAACCCTCCCCCCCATTTTTTCCCCTCTATTCATCAAACCTTTATGTATCTTTCATCTTCCAGTTACCTCTAGGCATTTAGATAGTGAAATTTACCTTTGAGATATAACAATAAGTGATTAACTGTTCACTTTCAGATGTAATGGCAAACAATTGTTAAAAGTTATTAACTGATCACAGATTTGCCTGGACTTCCCTTCCCAGGGAGGGAACAGAAGTTAGGAGGCAACTTTGGGATGGTGCTAGAGCATGGAAAGCACAGAGAATTGGACAAACAGGTCTTTTTCTCTTTTCTCTGATGTTTTACCTTTAAAAGATCCAACATCCTTACCGTTGGTATTTTTAGTAAGGTTATAGTAAATAGCTTTACACCAGGATGGattctgaaatataaattctaaattatatttgttataactatattttatgttgtatgttATCAGGAGCCATCAGAGAATGACCTTTTTGTGTTTGGAACACTTGGTTCCATGAAAAGTATGCTTTGTGTTTTAACTGTTAAAATAATTTAAAAATTAATTATTTTACATAATTAAAGAAGTTAAAAACTATTAACATTAAATAATTTCACAATTTCAACATGTCAAACCTATGAAGGGAGATAGGAAACAATGAGAAACTTACTTTTGCTCCTTTATACAGAATTATTAACTATATTTTACTAACTAAAAAACTCTAGTATTCTTTACCTAAAGTCAATTGGCTGGTAAGAGGGAGAGATGCAAAATTCTCCAGCTCTGAACTTGGAGCTACTTCACACTCTACTCTTAATGGAAACTTGAACTAATGATAGATAGTATTTTTTTCCTCTATTTAAAATTTTTGTCTTGATTAGGAGATTTTTCAGTTCTCCATATAATAATTTTCTACAATCAGATCTATGCTGTGGCATATTTTGCTTTATTTAAAAAtttttttttagagatgagttcttgctctgtcacctaggctggagtgcagtggcatgatcatggctcactgcagccttgaccttccagcctgccaagtagctgggattacagacaggcatgtgctattacacctggctaatttttaaagttttttttgtaaagatagggtctttctatgttgcccaggctcgtcttgagctcctggcctcaatcgatcttcctgccaaggttttggaattacaggtgtgagccaccatgcctggccTGCTTTGACATATTTTATAGTGTGTTAATTACAAATAGTCTTCATATGCCAGAATATAAGAGCAAGTGTTATCTACTTTTTAGATGGGAATTGCAGAAGCTGCATCAAAAGTATGCTTTGAGGTATATATAGTGAAACAGAGCCTTTCTGAAGAGAATTATATCAAACTAATTACAACCAAGAAATAATAGTATGAAGCGGATGCTGTTTGGAGGACAGGAAAATTTATCGGGAAAATTACATaatccctctgattccactatccagagatagccattattattaatatttggtatgtacatccttatattatttttttcttatgcatgattttgtatatatggttatttttctttccataaaaatggtattaaactgtatatactgttttgtagcctacatatttcatatagaagtatattgttaacattttccatgtcaataaatattcttctatggcttaaa

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