Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name CCT7P2
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:92889371-92890854  UCSC
Coordinates (T2T) chr5:93373454-93374937  UCSC
Coordinates (hg19) chr5:92225078-92226561  UCSC
Strand -
Parental Sequence NM_006429.4
Parental seq. overlap 1273 bp
Parental seq. overlap (%) 68.5%
Genomic Region Intergenic
Retrocopy Summary CCT7P2, located on chr5:92889371-92890854, is a retrocopy of the parental gene CCT7. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CCT7
Full Name chaperonin containing TCP1 subunit 7
Also known as CCTETA|CCTH|NIP7-1|TCP1ETA
Coordinate chr2:73233425-73253008
Strand +
Gene summary This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6. [provided by RefSeq, Oct 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CCT7P1
Bonobo Pan paniscus CCT7P1
Gorilla Gorilla gorilla CCT7P1
Orangutan Pongo abelii CCT7P1
Gibbon Nomascus leucogenys CCT7P1
Green monkey Chlorocebus sabaeus CCT7P1
Crab-eating macaque Macaca fascicularis CCT7P2
Rhesus Macaca mulatta CCT7P2
Baboon Papio anubis CCT7P1
Golden snub-nosed monkey Rhinopithecus roxellana CCT7P1
Marmoset Callithrix jacchus CCT7P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CCT7P2
AATAAGCTTCTTAAATGATGTCCACACCAGTTATCCTGTTGGAAGAGGGAACTGATAGTCCTCAAGGCATCCCCCAGCTTGTGAGTAACATCAGTGCCTAACAGGTGATTGCTGAGGGTAGAAGAACCACCCTGGGTTCTCATGGCACAGACATGCTTATTATGGATGGCAGAGGCAAGCAACAATCTTCTTGAAGCTTCTTCAATTTGTCCATCCTGCAGCAAAGACTTCAATGGACATTGCCAAATACCAAGATGCCAAGGTGGGTGATAGCACCACCTCAGTGACCTTACTGGCTGCAGAGTTTCTGAAGCAGGTGAAACCTTATGTGGAGGAAGGTTTGCACCTGAAGATCATCATTCAAGCTTTACGCACAGCCATCCAATTGGCAGTTAATGATAACAAAGAGATCACTGTGACCATGAAGAAGACAGAAAAAGTGGAGCAGAAGAAGCTGCTTGGAGAAGTGTGCCATCCTGCTCTGAGCTCCAAGCTCATCTCCCAGCAGAAAGCCTTCTTTGCAAAGATGGTGGTTGATGCAGTGATGATGCTTGATGGTTTGCTGCAGCTTAAAATGATTGGAATCAAGAAGATACAGGGTGGAGCCCTAGAGGATTCCCATCTGTTACCTGGTGTTTCATTCAAGAATTTCTTTTATGCTGGTGTTGGAAATGCAACCCCAAAAGTGCTATAATCCCAAGATTGCACTTTTAAATTTTGAGCTTGAGTTGAAAGTTAGGAAAGATAAGGCTGAGATCAGAGTCCTCACAATGGGGAATTACCAGGCAATTGTTGATGCTGAGTGGAACATTCTCTATGACAAGTTAGCAAGGATCCATCATTCTGGAGCCAAAGTTGTCTTGTCCAAACTCTCCAATGGGGATGTGGTCACTCAGTACTTTGCTGACAGGGGCAGGTTCGGTGCTGGCTGAGTACCTGAGAAGGATCTGAGTAGGACAATGATGGTCTACAGAGGGTTAATCCAGACCATTGTGAATGCTCTGTCAGCAGACATGACATGCTGGGCAGCTGCCAGGTGTTTGAGGAGACCCTGACTGGAAGTGAGAGGCACAATTTCTTTACTGGCCTCCCAAGGACAACACATGCACCTTTATCCTCCACAGTGATGCCACAACTTATGGAGGAGACAGAACAGTTCATGCCTAATTCCATCATGATTGTCAGGAGGGCCATTGAAAATGATTTGGTGGTGGCTGGTGGTGGGGCTATTGAGATAAAGCTCTCCAAGTACCTATGGGATTAGCAAGGACTATTCCAGGAACACAGCAGCTAGAGTGGGGGGTATGCTAAGGCTTTGGAGATTATCCCATGGCAGCTAAGTGACAATACTGGCTTTGATACCACAAACATTCTCAACAAGCTGTGGGCATAGCATGCCCAGAGAGGCACATGGTATGGCATGGACATCAATGATGAGGATATTGCTGACAACTCTGAGGCCTTTGTGTGg
>NM_006429.4
ATTGTGGGTTGCTGGGCGGCCCGGTCTCGGAGAAGAGGGGAGAGTGGCGGGCCGCTGAATAAGCTTCCAAAATGATGCCCACACCAGTTATCCTATTGAAAGAGGGGACTGATAGCTCCCAAGGCATCCCCCAGCTTGTGAGTAACATCAGTGCCTGCCAGGTGATTGCTGAGGCTGTAAGAACTACCCTGGGTCCCCGTGGCATGGACAAGCTTATTGTAGATGGCAGAGGCAAAGCAACAATTTCTAATGATGGGGCCACAATTCTGAAACTTCTTGATGTTGTCCATCCTGCAGCAAAGACTTTGGTAGACATTGCCAAATCCCAAGATGCTGAGGTGGGTGATGGCACCACCTCAGTGACCTTGCTGGCTGCAGAGTTTCTGAAGCAGGTGAAACCCTATGTGGAGGAAGGTTTACACCCCCAGATCATCATTCGAGCTTTCCGCACAGCCACCCAGCTGGCAGTTAACAAGATCAAAGAGATTGCTGTGACCGTGAAGAAGGCAGATAAAGTGGAGCAGAGGAAGCTGCTGGAAAAGTGTGCCATGACCGCTCTGAGCTCCAAGCTGATCTCCCAGCAGAAAGCTTTCTTTGCTAAGATGGTGGTGGATGCAGTGATGATGCTCGATGATTTGCTGCAGCTTAAAATGATTGGAATCAAGAAGGTACAGGGTGGAGCCCTCGAGGATTCTCAGCTGGTAGCTGGTGTTGCATTCAAGAAGACTTTCTCTTACGCTGGGTTTGAAATGCAACCCAAAAAGTACCACAATCCCAAGATTGCCCTTTTGAATGTCGAGCTCGAGTTGAAAGCTGAGAAAGACAATGCTGAGATAAGAGTCCACACAGTTGAGGATTATCAGGCAATTGTTGATGCTGAGTGGAACATTCTCTATGACAAGTTAGAGAAGATCCATCATTCTGGAGCCAAAGTTGTCTTGTCCAAACTCCCCATTGGGGATGTGGCCACCCAGTACTTTGCTGACAGGGACATGTTCTGTGCTGGCCGAGTACCTGAGGAGGATCTGAagaggacaatgatgGCCTGTGGAGGCTCAATCCAGACCAGTGTGAATGCTCTGTCAGCAGATGTGCTGGGTCGATGCCAGGTGTTTGAAGAGACCCAGATTGGAGGCGAGAGGTACAATTTTTTTACTGGCTGCCCCAAGGCCAAGACATGCACCTTCATTCTCCGTGGCGGCGCCGAGCAGTTTATGGAGGAGACAGAGCGGTCCCTGCATGATGCCATCATGATCGTCAGGAGGGCCATCAAGAATGATTCAGTGGTGGCTGGTGGCGGGGCCATTGAGATGGAACTCTCCAAGTACCTGCGGGATTACTCAAGGACTATTCCAGGAAAACAGCAGCTGTTGATTGGGGCATATGCCAAGGCCTTGGAGATTATCCCACGCCAGCTGTGTGACAATGCTGGCTTTGATGCCACAAACATTCTCAACAAGCTGCGGGCTCGGCATGCCCAGGGGGGTACATGGTATGGAGTAGACATCAACAACGAGGACATTGCTGACAACTTTGAAGCTTTCGTGTGGGAGCCAGCTATGGTGCGGATCAATGCGCTGACAGCAGCCTCTGAGGCTGCGTGCCTGATCGTGTCTGTAGATGAAACCATCAAGAACCCCCGCTCGACTGTGGATGCTCCCACAGCAGCAGGCCGGGGCCGTGGTCGTGGCCGCCCCCACTGAGAGGCACCCCACCCATCACATGGCTGGCTGGCTGCTGGGTGCACTTACCCTCCTTGGCTTGGTTACTTCATTTTACAAGGAAGGGGTAGTAATTGGCCCACTCTCTTCTTACTGGAGGCTATTTAAATAAAATGTAAGACTTCA

Publications

PMID - Link Title