Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CENPOP1
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:99594884-99595320  UCSC
Coordinates (T2T) chr5:100091883-100092319  UCSC
Coordinates (hg19) chr5:98930588-98931024  UCSC
Strand +
Parental Sequence NM_024322.4
Parental seq. overlap 345 bp
Parental seq. overlap (%) 8.3%
Genomic Region Intergenic
Retrocopy Summary CENPOP1, located on chr5:99594884-99595320, is a retrocopy of the parental gene CENPO. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CENPO
Full Name centromere protein O
Also known as CENP-O|ICEN-36|MCM21R
Coordinate chr2:24793425-24822376
Strand +
Gene summary This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CENPOP1
Orangutan Pongo abelii CENPOP1
Gibbon Nomascus leucogenys CENPOP1
Green monkey Chlorocebus sabaeus CENPOP1
Crab-eating macaque Macaca fascicularis CENPOP1
Rhesus Macaca mulatta CENPOP1
Baboon Papio anubis CENPOP1
Golden snub-nosed monkey Rhinopithecus roxellana CENPOP1
Marmoset Callithrix jacchus CENPOP1
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CENPOP1
AGAAGAAATAGCTGCAGAACACTTACAGACTGATATTCAGCACTTCCTTCTCAGCTTCTGCAAGTACCTAACTGCTCACTCTGGGAGAAAGTAACAGGCACACTCACTTCAGAGTGACTGCAGGCTTTATTTCTGATGGCCCCTTGCAGAGAAACTCACTGTGAAACTTTTTGTCATTTACTTACAAACTGGATCCAATGGGTAACCTTTCTTATTTGGTGCTGGATTGATGGAAAAGAATTTCACAATAACTCTTCCCACTGACCTCACCGTTGTGTATCAAGGAATAGAAGTGTCATTCACTTCATAGGAGGCACAGGAAGCATCCTATGAAACTTTGTTCTGTATGAAGTGCCTACATCAAGAGTTCCCTTCATTTGCAAGAAAAGGAAAAATGTTTGATATGAACCTGGTCTCTTAAAATATTATTTTCACTG
>NM_024322.4
AGGATCGCAAAGCACGCCGGGACCGGTTGGTTTGGTTTTGAAGACGTGGATGGCGGGAATTCTCGCTTCTGGCCTGGGTGAGCTAGAAGGGAGAAGCAAGGACATTGGAGTCCCTATCACCGGTTGCCTAGACAACTTCATGGGAAGGCCCTTGGGAATCTGAGATGGAGCAGGCGAACCCTTTACGTCCAGATGGCGAGTCCAAAGGAGGTGTTTTAGCTCACTTGGAAAGGCTAGAGACCCAAGTGAGCAGATCCCGTAAACAGTCTGAAGAGCTGCAGAGCGTGCAGGCCCAGGAAGGTGCTCTTGGAACCAAGATTCATAAACTAAGGCGTCTGCGAGATGAGCTGAGGGCTGTGGTGCGGCACCGGCGAGCCAGCGTGAAAGCATGTATTGCCAATGTAGAACCCAACCAAACAGTGGAGATCAATGAGCAAGAAGCATTGGAAGAGAAATTGGAAAATGTGAAAGCCATTCTGCAGGCATATCATTTTACAGGCCTCAGTGGTAAACTGACCAGCCGAGGAGTTTGTGTCTGCATCAGTACTGCTTTTGAGGGGAACCTATTGGATTCCTATTTTGTGGACCTTGTCATACAGAAACCACTCCGGATACATCACCATTCAGTCCCAGTCTTCATTCCCCTGGAAGAGATAGCTGCAAAATATTTACAGACCAACATCCAGCACTTCCTGTTCAGTCTCTGCGAGTACCTGAATGCTTACTCTGGGAGGAAGTACCAGGCAGACCGGCTTCAGAGTGACTTTGCAGCCCTCCTGACTGGGCCCTTGCAGAGAAACCCACTGTGTAACTTGCTGTCATTTACTTACAAACTGGATCCAGGGGGTCAGTCCTTCCCGTTCTGTGCTAGATTGCTGTATAAGGACCTCACAGCAACTCTTCCCACTGACGTCACCGTGACATGTCAAGGAGTGGAAGTATTATCCACTTCATGGGAGGAGCAACGAGCATCTCATGAAACTCTGTTCTGTACGAAGCCCTTGCATCAAGTGTTTGCCTCATTTACAAGAAAAGGAGAAAAGTTGGATATGAGTCTGGTCTCCTAATAGATTGTTTTCACTGCACTGGGAGCACATCAGAGAAATAAATCCCCCCTCCCCTGCCAGGTGAAAGGAAATATTGCACTTTCTGTTCTCATGACTAAGGGGACAGGAGTTCCAGAAGAACCTTTCAAGATGATCAGGAACACCAGGACGAGGGCCGTCTCACCTCACTCGGACCACATGGAGACCTCCCTTCAAAATGGGAGCCATGTCCTGCCCCACCAAGCCCTGTCTGAAGTGGAGCTTCCCCGCCTGTGCTCCCTCCACAGTCCCGGAAAGCCCAGCGGCAAAGGCAGCTTTGTCCCAGCTCTGCCACCCTCCTGCTCACAGTGGTCAGGGCCCCTCAGGGGCAAGGACGGCAGGGATTGGAACGAGGGCTCTGGAAGGACTGTTCAGCCCTATGCCTAAGACCCCTATGCTGGGGACACTACAGGCACACACAGGAATAGCAGGGCCACCCTCAGAGCTCACACATCCACGAACAAATGAAGGCTGAGGAGGTTTCTAAACCTAAAGTCCATGAGTGTGCACTTCAATCCAGGAAGGTCGGGACTTCCTTCAGTTTCAAAAAATAAATTCTCCCTTCCGGTTTGGACTGTTGCAGGCTCGAGGCCATTCAGGAGTTGTCCACCACCTGGTGGGGCAGTGTGACAGAGGGGCCATTGGGGAAGGTGGCTAGCTTATCCCGCCCCTTCAAGAAGAAGGTCAGCAGCTCCCCCTTCCCCTTCACAAAGATGGGGCCTCGCCTCACAAAGCGGAAGCCGTACTCTCGGAGGATGACTTGGGTTTCTTCTACCACCTGGAGAGGGAGGGGGAGCAAGAACGTGGCGTTACGGGGGGAGCCTAGACTGAGGGCGGGTGGGGGCTTTGGGTGGTTGGAGCCGAGCACTGATCCATGGGTCCCAAGCAGTACGGGACACTCCCCAAACCTCCCAGGGCCAAGCCCTTCCACCCGTGGCGAGCAGCGGGTGGGAAGGAGAACCCTGGAGTGACTGGCTGGGGGCCTCCTCTCATCCAGAGACTTCTCTCCTAGGATGGCCATGGTCACCTGGGTGGCAGCACTGTTACCTGGAAACTGCCACTGCCTGCTCTTCTGTCCCTTTGCCCCTTTCGTGGAGCTTTTCTGCCAGACGCCACTGAGACAGATCACAAGGTATTAGAAGGTTCATACCCAAAGGTAGGCCATATGCATCTAGAACTTCAGCCCAGATTTTGTGGATGGGTGGAAGTGTTTCTTCCTGTGCTGAGGCTAGCTATTGCAGAGATTCTTTTCCACTTGCCCCACGTCTCTGCCTCTGGACTTACTGTTCAGGGCCAGGGTGGGAGGCAGGGGCACGTGGGAAAGCACTGTTCCGGTTTTGTTCTCATGCCGAGTCTGAGCACGTGCCAGCTGTGCCACTGGACATACCTGAATGTTGCCCATGACCCCCGTGGACTCCATCCTGCTGGCTACATTGACTGTATTGCCCCAGATGTCGTAGTGTGGTTTCCGGGCTCCGATGACCCCAGCCAGAACCCCGCCTTTGTTCATGCCTAGGGTAGAGGCATAAAGTTCAGCACAGCCACAGGCCACACCTTGTTATGGGCCTCAGAAGCCATCTCCTCTCCAGACCTGTACCACAAAGCTCCTAATGTAACACATCATTGTCCTCATTCAACTTGGCTGTATGCTATTGGAGGGTGGAAATCACATCTCCTGTTTATCCGTGTGCTTGTTAGGTGTCAGCCGCCACCCCCCCCCCATATGCAGATTTACTCGGCATGGTAGTGGCCAGCTTCTAACACAGCTGGTATTTCAAGTCTCCTGGGACCTCACTCAGGAATGATACCCCCTCAGTAGAAGCAGCAGGTGATCTTAACTCCTTTCAAAGAGCAGGCCTGTCTGGGAAGCCATGTCCTCAGCAGGCACAGCAACCCCTCTGGAAATGGATCACAAACTCACTTCTCAGCCAGGCAGGCCAAGCTTCTATTGTAACAGTAGGCACAGTATAGTCGGATCATCACATCAGCTGGGTTTTTGGTTTAGTCATCTAGAGTCGTCTGGACTAAAGGTCTTTCAGGTCTCCTTGCCCTGTGAGTGCGTGAACCTCCCCACCCGAATTGCCTCAGTTGTCCTGAGCCTCATGTCTCTCCTGGTGGTGGGCCAGGCCCCTGCATGGGAAGGGAGCCTGCTGCGGGGCAGGCCAGCTGGGGGTGCTCACCTATGCGCAGCATGAAGTTATTGAAGGACTGGTTGTTGATGTTGGTGAGCGTATCCTTCATGGCCAGCGCGAAGTCGGCCAGGTCAGCCAGGTGCTGCCAGCGCTCTCTCTCGGACTTGTCTTCCTGTGCCAGGGGACCGTGGAGAAAGTGTCAGGGGCCGCTCACTGCAGCAGCCTGCTCTGCTGCCTTCCCTGGCAGTGTTCTGGGGGTGGATTCCCTACACCTAGATGTTCAAGGCCTTACTTTTCCTCCCACAAAGGAGTCGCAGCCACGCTAGCTCTGACTTGCCACTGTGACAAAGTTCACGTAGCAGGTCTAGGCAAAGACTGGGCAATTGAGCAGAGGAGACGGACCTGTGAGTCTGACCACGAGGCGGACCCCTTCACCTTGGCTGGGCCTGGTCCTGGTCCTTAGGTTTTGTCAGGTTGTCCTTGTTTGGATCCCTCAACTAGGTGATAAGCACTGGAGGGGGATGACCCGCCTTGGACGTGTTTCTTTAACCTCATCCATATAATAGGGCCGTGGGATGGTTGTAGAGGTAAAGCAGGATGATGGTGTTTTAAGACCAGAGCTTGGGACCAGGGCTCCTACACCTAATTTTCTCTCCTGGTAGCTGAACAAAGGTCTAAATTAGCTTAACAAAAGAACAGGCTGCCGTCAGCCAGAGTTCTGAAGGCCATGCTTTCAGTTTCCCTTGTTGACAATTGCTCTCCAGTTCCTATGAAAGCACAGAGCCTTAGGGGGCCTGGCCACAGAACACAACCATCTTAGGCCTGAGCTGTGAACAGCAGGGGGTTGTGTGTCTGTTCTGTTTCTCTGCTTGCCGAACTTTCTCAATAAACCCTATTTCTTATTTATA

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