Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TTC22P1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:100092078-100093764  UCSC
Coordinates (T2T) chr6:101265796-101267482  UCSC
Coordinates (hg19) chr6:100539954-100541640  UCSC
Strand -
Parental Sequence NM_017904.4
Parental seq. overlap 572 bp
Parental seq. overlap (%) 24.8%
Genomic Region Intergenic
Retrocopy Summary TTC22P1, located on chr6:100092078-100093764, is a retrocopy of the parental gene TTC22. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TTC22
Full Name tetratricopeptide repeat domain 22
Also known as -
Coordinate chr1:54779696-54802379
Strand -
Gene summary This gene encodes a protein with seven tetratricopeptide (TPR) repeats. Tetratricopeptide repeat containing motifs are found in a variety of proteins and may mediate protein-protein interactions and chaperone activity. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2011]

Homology

Species Scientific Name Retrocopy
Gorilla Gorilla gorilla TTC22P1
Orangutan Pongo abelii TTC22P1
Gibbon Nomascus leucogenys TTC22P1
Green monkey Chlorocebus sabaeus TTC22P1
Crab-eating macaque Macaca fascicularis TTC22P1
Rhesus Macaca mulatta TTC22P1
Baboon Papio anubis TTC22P1
Golden snub-nosed monkey Rhinopithecus roxellana TTC22P1
Marmoset Callithrix jacchus TTC22P1
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TTC22P1
GCCCATTTGCTTGGAGCACAGACCTGGGGCTCTGAGTTTACTTTGCTGCGAGCTAAAGAGTTCCCCCATCCCCTCCTTTACTCTACTACAGTTCACATGACCTAGTGGCAAATCTGCTCCTAGTCTTGGTCTCAATGGCTTAATTATTTTGCCAGCAAGTATGAGGCAAGAGTGAAATCCTTCACTGTAGTTGATGTGGTTTAAGTAGCTGACTGCTACTATTAGATATGTTTTCTAATTCTGTAAGGTTTTTGAGTGAAAGAATGAAGGAGCAGATCCAAATGGAAGAGAAAAGGGGCTGGTACTTCACTATGGCAATGCTCTTCATCAGGCTAGATGGCATCTTCCTGGAGCTGGGCAGAGAGAAGCAGAAAAGGCTGCCCACCTTCAACTGCATGCTGGCCCTGCTCCAGCAAGTGCTCAAGTCTGAGGACCTCCCCCACTACCGAGCCCTGGCCTGGTGTTGCAACAGAATGCTGCTGGAGAGGAAGGACCCCTTATCCATCACCACCATGGGCATCCATACTGTGAGTACTCGGAGACCGACCCTCTGGACTGCTTTGGCAAGGCCTTCGAGATCGCCAAGAACCAACCTCCCATCCTGTATCACCCGGCCAAAATATTCCACTTAGGAAAGCAGGATATGGCCACTGGAACCTGCAACATGGCCCTGAATGTCCTACAAGATCCAGAGCTCAACTGGCAGACATACTGCACAAGGGCTGTg
>NM_017904.4
ACCTGCGGGAGGCGCCCTGAGACCGAGAGGCCGCAGCGCCCGGGGCCTCTGCCGGCTGCCCCTCGCCTCCCGCACGGAGCTCGCTCGGGGAACGCCCCCATCCACTGCCCTCCACAGCCTCAGGGACAAGGGTGAGGCCAGGGGAGCAGAGGGAGCAGTCATGGCGGAGCTGGAGGCTGTGGCCGACGATCTAGACGCCCTCATCGACGACCTGGACTACCTCCCGGGCCACTTTCACCTGGAGATGCAGTTGAACTTCGAGCCGCGCTCGCCGGCCCCACAGCGCGCCCGGGACCTGAAGCTGCAGCGGGAGGGTCTGCGGCAGGAGCTCCAGCTGGCGGCCGCCCCGCAGCGCCCCGCTGTGCGTCACCTCCTGGGCGCTTTCGCATTCTACCTGGAGGAGCTGGACGAGGCCCGCGAGTGCTTCCTCGAGGTGGCCCACGAGCACCCGGGCAACCTCAATGCCTGGGCCAATCTGGCACACGTGTACGGGCGGCTGGGCCAGGAAGAAGAGGAGGAGGCGTGCGCCGCACGGCTGGCCGACCTCATGGGCCTGGCAGAGGAGCCCGAGGCCGCCGGGGACCCCCAGCTCCGCGCCGCTCGCTGCCTGGCCGAGCAGGGCTACGCGCATGGCTTCGACGTCGGCTGCGCCAGCCCAGAGGAGCGTGCGCGGGGGCTGGCGGCAGGCATCGCGCTCTACGACAAGGCGCTAGGCTACGGGCAGCAGATCCCGATGGAGGAGAAAAGGGGCTGGTATTTCACCATGGCAACACTCTACATCAGGCTAGATGGCATCTTCCTGGAGCTGGGCAGTGAGGAGCAGAAGAGACTGCCTGCCTTCAACCGCACGCTGGCCCTACTCCGGCAAGTGCTGAAGTCCGAGGACCCCCGCCACCGAGCCCTGGCCTGGTGCTACCTCGGGATGCTGCTGGAGCGGAAGGACACCTTCTCCACCACCCCCATGGGCGTCCATGACTGCGGGTACTCAGGGACCGACCCTCTAGACTGCTTCGGCAAGGCCATTGAGATTGCCAAGAACCAACCTCCCATCCTGAATCGCCTGGCAAAAATCTTCTACTTCCTGGGAAAGCAGGATATGGCCATTGGAACCTGCAACATGGCCCTGGATGTCCTACGAGATCCAGAACTCAACTGGCAGGCGTACTGCACAAGGGCCAAGagacgaggtctcactatgttgcccagactcgtctcaaactcctgggctcaagcagtcctcccacctcgacctcccaaagtgctggaattccaggtgtgagccactacacccagccCTGTAAGGTTTTTGAGTGAAAGAATGCAGGagcctccactcactgcaggaatcccttctacaattcctggtcagtgagcccccagcctcttctggaTTGgcacgggtggaatcagactgaccagagttgaaatctggcttctccgccttgtggaacttgcagcaagccacttacccccacaaacttcagttcccaaatctgtaagatataaataacaacactttccttaaaatgttgtcaacagacacagtgaggtagcatctaaagcacagtgccttggacatagggggtgctTTTCTGAAAGCCAGTagaggtcatttaatatagtggatcagagctctggctctgaacacagacagccttggttcaaatcccacaacaccacgtgctacgggacctttggcaaaatactcttgcccagattctgagcctcaatttctttatctgtagactggagttgttatgagaattacattagattttgtatgtaaaactcagcatcaagcacacagtaagATTTCATAAGAGACTGACTGCTACTAATTTAATATTAGGCATATTTTTGAATTATctcactgtctcttgatgcagtccactgcatagtcattcagctctgcaagttacacacttaggtgagttctgcctcctgctagcttcccgcactggtcccagacctgcctcctagagcccacacagaGCCCATGTGCTTGAGGAAGCCGACTCGGAGCTCCCAGTTTACTTCACTGCAAGCCGAAGAGTCCTCCCATCCCCTCATCTTCTCCACTACTATCCACATGACCTAGTGGCAAATCTACTCCCAGTCTTGGTCTCAGTGGCTTAATTACTTTGCCAGCAGGTACGAGGCAGGAGTGAAATTCCTTCACTGTCGTGGATGTGGTTATTATTCTAGATAATAATGACATTAACCATAATAGTAaataataaaatatctctataaaattctgcatttcatcaagca

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