Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NUDT19P3
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr19). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:114018668-114020351  UCSC
Coordinates (T2T) chr6:115201771-115203454  UCSC
Coordinates (hg19) chr6:114339832-114341515  UCSC
Strand -
Parental Sequence NM_001105570.2
Parental seq. overlap 867 bp
Parental seq. overlap (%) 27%
Genomic Region Intergenic
Retrocopy Summary NUDT19P3, located on chr6:114018668-114020351, is a retrocopy of the parental gene NUDT19. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NUDT19
Full Name nudix hydrolase 19
Also known as RP2
Coordinate chr19:32691363-32713792
Strand +
Gene summary Predicted to enable magnesium ion binding activity. Predicted to be involved in purine nucleoside bisphosphate metabolic process. Predicted to be located in cytosol and peroxisomal matrix. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NUDT19P1
Bonobo Pan paniscus NUDT19P1
Gorilla Gorilla gorilla NUDT19P1
Orangutan Pongo abelii NUDT19P1
Gibbon Nomascus leucogenys NUDT19P1
Green monkey Chlorocebus sabaeus NUDT19P1
Crab-eating macaque Macaca fascicularis NUDT19P1
Rhesus Macaca mulatta NUDT19P2
Baboon Papio anubis NUDT19P1
Golden snub-nosed monkey Rhinopithecus roxellana NUDT19P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NUDT19P3
ATCCACTATATTGGCACTTTTCCTGATGTGCTTTGGAGGATGATCCATGAATTTCTTAGACACTTTGCTGGAATTACTTCAAGGGTGTCTGATTAGATGGTGAACAGGAGACTGAGACAAACTAAAAGTGACCATGTCATTGTTTTCTTGCTATGTCTTTAGCTTGATGATTAAGATACAATTCCTTTTAAAACGAAATGACATTAGTTATTATGTTTCCCAAATTAGAAATCTATTTTAGTTGATATTTTAAAGGAACGTGAAGCCATAACCAAAACCATCATTGTTTTTACGCCAGAGTGTTAATGAATGTAAAGAGGTTACAGAGGTGTGGTGTTTAATTAGTGATGTTTATTTTTACTATATTTAGTGAGTAATTTTTCATTGTCTTTAAAGACAAATAATATTTATTGATTAAAGGTGAGAAGGGCTGAAGAAATCATGAAGGAAGGCAAGCAGTTTCACAGAATAGTGATATCCAATCACAATCTTTATGATATCTACGTGAGTGTTCAAAGTGTAAACACGTTTATCCCAAGAACTCCTTAGTAAGAAAGAGCCATCTGTAGGGTGCCCGTGCTTGTTTATAAACTGGCTTACTTGGAGTCCTTGTGAATAATGAGGGTTGAATTTCAACTTGCTTGAAACGTAAGGAACTTTGTGTCAATAAAAGTTATTATAATGCACTATTTCTTATTTCAAGTGTTTTAGGGAGCTATCTTGCTTATTTTATTCTTTAAACCTTCAGTGTGCCACATGTATAAAGTTTATAAAGTATTAATGATCTTGTTAACCAAAATAAGAAAAAAATTTCACAAGGGTTCCCACTCTTGTATTGTTTTATTATCTCAAAAGTTTAAATAATACCCTGACTTGGCCAAGGTGGTGGGCTGCCAGTGCTCATCTCTGTCAGTTGCAGCTGAGAGTTTCTTATCAAAAGAAATGTGGTTGGCACCCCCACAGTTCTACGAAATAAGAAGGCTTGAAAACTTGGCCTCTCTCCCTGACTTGCACAAATTGTGTTTGGATGGTACATTAGAAAGATAGAAAAGATGGCTGCCCATCACCTTGTTAACCGCTGATGGGAAGCTCCAGCTTTTTGCAGTTGATGAGCTACACTTGGAAGATTCAGACTTTTTAGAAAAACTTTTTTCTACTGCAAAGAAAGACTGg
>NM_001105570.2
AAACGCCCAGGTTCACCCAACGCCAGAGGCTCGTCCTCAATTCCCGCGAGGCCCCCGGAGGTGCTGGGGTCCCTGCAGGGCCGGGCCACCTGCCGTGGAGCTCAGGCCGCGCCAGAATCGGATCCGGGAAGCTGCGCGCCATGAGCAGCTCCCTGCGGCCGGGCCCCAGCCGCTGGCGGCGGGCGGCCAGCATCGTCCTGGCGGCTGGCTGGTCGCGCCCGGAGAccgccaccccgccgtcgcgcccgccgccggccgAGGGCTTCCGGCTGCTGCTGCTGCAGCGCTCCCCGCACCAAGGCTTCATGCCGGGCGCGCACGTCTTCTCCGGCGGAGTGCTGGATGCGGCCGACCGCTCGGCGGACTGGCTGGGCCTCTTCGCGCCGCACCACGGGCCGCCGCGCTTCGGCCTGGGCCCGGCGCCATTCAGCCGCACCGCTTTCCCGTCGCTGCCCGACACCGATGACCACAAGACCGACAACACTGGGACGCTGCCTGAGGACGTAGCCTTCCGCATCTGCGCCGTGCGGGAGGCCTTTGAGGAGGCGGGCGTGCTGCTGCTGCGGCCCAGGACTTCCCCACCAGGCCCAGCACccgggcctggcctcgccctggagccaccgccgggcctggcctcctggcGCGACCGCGTGCGCCAGGACCCGCGCCACTTCCTGCGGCTGTGCGCCCACCTCGACTGCACACCCGACATCTGGGCGCTGCACAACTGGAGCGCCTGGCTCACCCCTTTCTTGCGGGGCACCACTCGCCGCTTTGACACGGCCTTCTTCCTGTGCTGCCTGCGCGAGCCGCCGCCCGTCTACCCCGACTTGGCGGAGGTGGTGGGCTACCAGTGGTCATCTCCATCAGAGGCAACTGAAAGTTTCTTATCAAAAGAAATTTGGTTGCCACCCCCACAGTTCTACGAAGTGAGAAGACTTGCAAACTTTGCCTCTCTCTCTGACTTGCACAAATTTTGTTTGGGTCGTGCATTAGAAGGACTGGAAAGGTGGCTGCCGATCATCTTGTTAACTGCTGATGGGATGGTCCATCTTTTACCAGGTGATGAGCTATATTTAGAAGATTCAGACTTTTTGGAAAATCTTATGTCTACTGAAAAAAAGACTGAGGAAATCATGAAGGAAGGCAAGCAGTTTCACCGGATAGTGACATACCATCGCCACCTTTATGATATCCACGTGACTGTTCAGCCAAAGTATAAACACGTTTATCCTAAGAACTCTGTAGTAAGAAAAAGCCATTTGTAGGGTGCTTAAGCTTGTTTGTAAAATGGCCTACTTGAAGTCCTCATGAATAATGAGGGTTGACTTTCATTTGCTTGAAACTTAAGGAAGTTTGTGCCTATAAAAGTTACTGCAATTCAGTAtttctttatttttttcgagacagagtctcaatctgtcgcccaggctggagtgcagtggcatgatataggctcactggaagctctgcctcaggggttcatgccattctcctgcctcagcctcccgagtagctgggactacaggcgcccgccaccatgcccagctaatttttttttgtatttttagtagagacgggttttcaccgtgttagccaggatggtctcaatctcttgacctcgtgatacgcccgccttggcctcccaaagtgctgggattacaggtgtgggccaccacacccagcctttttttttttttttttttttttttttgagacagagtgtctcactcttgcccagaacccaggctggagtgcagtggcccaatctcggctcactgcaacctccacctcccaggttccagcgattctcatgcctcagcctcctgagtagctgggactataggcatgcaccaccatgccccactaaattttgtatttttagtagaaacagagtttcaccatgttggccaggctggtctcgatctcctgacctcatgatctgcccgccttggcctcccaaagtgtgggattacaggcgtgagccactgtgcccagcATGGTGTTTCTTATATCAGGTGTTTTAGGGAGCTCGCTTGCTTATTCCATTCTTTAATCCTTACAGTGTGCCACACGTATAAAGTTTATAACGTATTAATGATCTCATTACCCAAAACCAGAACATAATTTCACAAGGGTTCCTACTTCTGTATTGTTTTATTATCTCAAAAATTTAAATAACATGTTCTGCTGTTTATTGTTCTTGTTATCCACTGTATTAGCACCTTCCCTGATGTGCTTTGGAGGTTGATCAATGAATTTCTGAGACTTTCTGCTGGAATTACTTTAAGGGTGTCTTATTAGATGATGAAAAGTTGGCTGAGACACCCTTCAAGTGACCATGTCATTGTTTTCTTGCTATGTCTTTAGCTTAATGATTAAGATACAATTCTTTTTAAAATCAAATGGTATTAGTTATTATGTTTCCCAAATTAGAAATCGATTTTAGTTAACattttattttattttattctattttatttatttttgagacagagtctcgctctgttgcccaggctggagtacaatggcgcaatctcagctcactccaatctccgcctcccaggttcaagcgatttttctgcctcagcctcccgagtagctgggattacaggcacccactaccatgcccagctaatctttgtatttttagtagagacggggtttcaccatgttggccagtccggtctcgaacttctgacctgaggtgatctgcccaccttggcctcacaaagtgctgagattacaggcttgagccaccacgcctggccTAGTTAGCATTTTAAAGAAACACAAAGCCATAACAAAAACCATCATTGTTTGTATTCCACACTGTTAATGAATGTAAAGAGGTTAGAAATGTAGTGTTTGATTAATGATGTTTATTTTTACTGTATTTAATATGAGTAATTTTTCATCATCTTTCAAGAGGAATAATGTTTATTGATTAAAGGTGAGAAATGATAGTTAAGACACCAATTCCATGTCCAGATCTTTGACTGTATCATGCATTGTACAATTGATTTCATATTTTATGAAATGCCTTAATTTTCCTACTATAACATAAAGACAATGATGAATAAAGTTTATGTGTATGATTAAA

Publications

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