Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name LSM14AP1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr19). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:121682913-121684949  UCSC
Coordinates (T2T) chr6:122869914-122871950  UCSC
Coordinates (hg19) chr6:122004059-122006095  UCSC
Strand +
Parental Sequence NM_015578.4_2
Parental seq. overlap 1841 bp
Parental seq. overlap (%) 53.3%
Genomic Region Intergenic
Retrocopy Summary LSM14AP1, located on chr6:121682913-121684949, is a retrocopy of the parental gene LSM14A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name LSM14A
Full Name LSM14A mRNA processing body assembly factor
Also known as C19orf13|FAM61A|RAP55|RAP55A
Coordinate chr19:34172499-34229288
Strand +
Gene summary Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Mar 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes LSM14AP1
Bonobo Pan paniscus LSM14AP1
Gorilla Gorilla gorilla LSM14AP1
Orangutan Pongo abelii LSM14AP2
Gibbon Nomascus leucogenys LSM14AP1
Green monkey Chlorocebus sabaeus LSM14AP3
Crab-eating macaque Macaca fascicularis LSM14AP1
Rhesus Macaca mulatta LSM14AP1
Baboon Papio anubis LSM14AP1
Golden snub-nosed monkey Rhinopithecus roxellana LSM14AP2
Marmoset Callithrix jacchus LSM14AP1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>LSM14AP1
TGCGGTGGCACCATGAGCGGGGTCACCCCTTTCCTCCACAGCAAGATCAGCCACATCTCCAAGGCACAGATCTGCTACGAGGGCATCCTCTGCACCATCGACACGTAGAACCCCACCGTAGCCCTCGCTAAAATTCAATTTTCTGGTACAGAAGATAGATCGTCCAATACCACCTCAAGATGAACTATTGTAATACATTGTATTCCATAGGAGTGACATTAAAGACCTCACTGTGAGCCACCAAAACCACAGTGTTCTTTGCCTGAAGACCCAGCTATCCTTCAGTCCTCACTAGGCTCATCAACTTCTTCATTCTGGTGCGTGGGGTTCTCATGGGCCTTTGGGCAGGATGCTCATATACAGTCGGTTCAGTCCAAGCTCCTTAGTTGGGCAGGAGTTTGGTGCCGTTGCTGTTGCTGGAAGCTCTTTGATATCGTTTGGAACAGAAACATCAAACAGTGGTGTCTTACCCCAAAGTAGTATGGTTGACTCTGCCTTAACACAGGATACAAGATCTCTAAAAACACAGTTATCTCAAGGTCACTCAAGCCCTCAGTTAGACCCTTTGAGAAAAAGCCCAACCACTGAACAAGCAGTGAAGACTGTCTCGGCCCATTTACCTGCTCCAGCACCTGTTGGGAGAAGGAGCCCTGTATCAACTAGGCAATAGAGATCAAGAGCACTGGTGAGCTGAAGTACACAATGTTTCAAGACCAGAAAATGAGCAACTCAGAAATGATAGCAAGAGACAAGTAGCTCCAGGTACTCCTTCAGCTCCAAGGAGAGGGCGTGGGGTTCAGCCGGGTAGCAGGGGAAGATTTCGTATTCTGCGAGATGGGCCAATGAAATTTGAGAAAGACTTTGACTTTGAAAGTGCAAATGCACAATTCAACAAGGGAGAGATCGACAGAGAGTTTCATAATAAACTTAAAAGAAGATAAACTGAGAAACAGGAGGAGCCTGTAAATGGTGAAGATAAAGGTGACCCAGGAGTTGATACCCCAAAAGTAAAGGAAGTGCTGATGAAGAAGATCCACTTGGACCTAACTGCTAGTAGGAAAAAACTAAATCCTTCTTTGATAATATTTCTTGTGATGACAATAGGGAACGGATATCAACCTGGGCTGAAGAAAGAAGATTAAATGCTGAAACATTTGGAATCCCACTTTGTCCAAATCGTGGCTGTGGGAGACGCAGAGGCAGAGGGATCTTCGGTTTCTGTGGTGGCAGAGGGCATGGTGGTAGCAGATGTGGTACTTTAACCATCCCTGGAGGATTTCGCAGTGGATTCAGAGGAGGTCCTGGGGGCAGGGAGTTTTCGGATTTCTAATGTAGGAAAGACAACAAAGTTGCTGTATAGTCTACAAACAAGTCTCTAAAAATAGGTGAATTTTTAGCTCTTCATGGTCCTGAAAATTGATTTCAGTCTTTGTGAAGAATCAAGTGAATTCACTGTACATTTGTCAACAGCACTGGGTTTTTGTTTTTTGTTTGTTTTTCTGCTTAATTTCAAAGATAAAATGCAGTTACTTTTTGGGGTTGCAGGGGAGAAAGCCTAATCTTAAAAAATGAACATAAAATATATTTGGAATAGCAGAAGGTTAAGTAATTTCTTATGTACAGTTAAGCAGTACTTCAGTGGGACTTATATTTTTTCATCACTGAAAGTGTATTTTTTAAATTACTAAATCATATTTGTCAATTGCAAGTGGCCTGCAGATAGGGCTGTGATACTGTGTTTTGGGCCACAGAAGGGTGTGTGTGTGCATGTCTGTATCTTTCTCCTTTTTTGGGGAATCCTATAATATGAGGTAGCTTATTTCATCAATTATTTAGGGTGCTGGATGGTAGAGAATTTTCAGTAGAGAATTTTCAGTTAACTAGGTACACACAGTAAATACTGTTTCTTAGGCAAAGGTAACTTTTTTATATAGTTGTAAAATTCCACTATATTCCATTGCCAAAGAAACATTAAGAACTTTGTATAGCCACATAAAAAGCAACCAAATTTTTAAAGAATAATCATTTTAAAGTCAG
>NM_015578.4_2
AGCGGAGCCGGCGCCGCCGCCATGTTGGGTCTGAAGCGGCTGCTGTAGGCGCCGACGGAGCGAGCGGGCGTGCGGAGCGGGCGACAGTGGCGTGGGATCTGCCTCTCTGCGAGCAGCTGGGAGCGGCGGCGGCGGCGCCATGAGCGGGGGCACCCCTTACATCGGCAGCAAGATCAGCCTCATCTCCAAGGCGGAGATCCGCTACGAGGGCATCCTCTACACCATCGACACCGAAAACTCCACCGTAGCCCTTGCCAAAGTTCGATCCTTTGGTACAGAAGACAGACCGACAGATCGTCCAATACCACCTCGAGATGAAGTCTTTGAATACATTATATTCCGTGGGAGTGACATTAAAGACCTTACTGTTTGTGAGCCACCAAAACCACAGTGTTCTTTGCCTCAAGACCCAGCTATTGTTCAGTCCTCACTAGGCTCATCGACTTCTTCATTCCAGTCCATGGGTTCTTATGGACCTTTCGGCAGGATGCCCACATACAGTCAGTTCAGTCCGAGTTCCTTAGTTGGGCAGCAGTTTGGTGCTGTTGGTGTTGCTGGAAGCTCTTTGACATCCTTTGGAACAGAAACATCAAACAGTGGTACCTTACCCCAAAGTAGTGCGGTTGGTTCTGCCTTTACACAGGATACAAGATCTCTAAAAACACAGTTATCTCAAGGTCGCTCAAGCCCTCAGTTAGACCCTTTGAGAAAAAGCCCAACCATGGAACAAGCAGTGCAGACCGCCTCAGCCCACTTACCTGCTCCAGCAGCTGTTGGGAGAAGGAGTCCTGTATCAACCAGGCCTTTGCCATCTGCCAGCCAAAAGGCAGGAGAGAATCAGGAGCACAGGCGAGCTGAAGTACACAAAGTTTCAAGGCCAGAAAATGAGCAACTCAGAAATGATAACAAGAGACAAGTAGCTCCAGGTGCTCCTTCAGCTCCAAGGAGAGGGCGTGGGGGTCATCGGGGTGGCAGGGGAAGATTTGGTATTCGGCGAGATGGGCCAATGAAATTTGAGAAAGACTTTGACTTTGAAAGTGCAAATGCACAATTCAACAAGGAAGAGATTGACAGAGAGTTTCATAATAAACTTAAATTAAAAGAAGATAAACTTGAGAAACAGGAGAAGCCTGTAAATGGTGAAGATAAAGGAGACTCAGGAGTTGATACCCAAAACAGTGAAGGAAATGCCGATGAAGAAGATCCACTTGGACCTAATTGCTATTATGACAAAACTAAATCCTTCTTTGATAATATTTCTTGTGATGACAATAGAGAACGGAGACCAACCTGGGCTGAAGAAAGAAGATTAAATGCTGAAACATTTGGAATCCCACTTCGTCCAAACCGTGGCCGTGGGGGATACAGAGGCAGAGGAGGTCTTGGTTTCCGTGGTGGCAGAGGGCGTGGTGGTGGCAGAGGTGGTACCTTCACTGCCCCTCGAGGATTTCGCGGTGGATTCAGAGGAGGTCGTGGGGGCCGGGAGTTTGCGGATTTTGAATATAGGAAAGACAACAAAGTTGCTGCATAGTCTACAAACAAGTCTCTGAAAATAGGTGAATTTCTAGCTCTTCATGGTCCTGAACATTGATTTCAGTCTTTGCAAAGAATGAAGAAGTGAATTCGCTGTACATTTGTCACCAGCACTGGGTTTTTGTTTTTTGTTTGTTTTTCCGCTTAATTTCAAAGATAAAATGCAGTTACTTTTGGGGGTGGAAGGCTCATCTTAAAACATGAGCATTAAATATATTTGGAATAGCAGAAGGTTAAGTAATTTCTTATGTATAGTTAAACTAAAGCAGTACTTCAGTGGGACTTAACAAGTATTTTTTCATCACTGAAAGGTTTTTTTTTTTTATCACTAAATTGTATTTGGCAATTGCAAGTTGCCTGCAGATAGGGCCGTGATACTGTGTTTTGAGCCACAGAAGGTtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtatgtgtgtgtCTTTTTCCTCCTTTCTTTTGGGGAATCCTGTAATATGAGGTAGCTTATTTCGTCAATTAATTAGGGTGCTGGATGGTAGAGAATTTTGTCAGTCAACTATGTACACACAGTAAATACTGTTTCTTAGGCAAAGGTAACTTTTTTATATAGTTGTAAAATTCCATTATATTCCATTGCCAAAGAAACATTAAGAACTTTGTATAGCTGTATAAAAAGCAACTAATTTTTTAAAGAATAAACATTTTAAAGTCAGCAAACATACTGTGTCCTTGCAGAAGTTGATGTGCTGAGCAGCAGCCTTATGGGTGGGTCTTTTTTTCTTAGTTTTCCAGGCTTAACATTTTTGATTTTGTTTTTTAATGTTTGGAACATAAATGAAGATTTGATACATTATTTCATTATCTAAAAAGGATTAATTATTCATGCTCATTGTAAGAACTTCATTTTGTAGCAAATGGCATATCACAGGATCTGTCCAGATAATCGATATTTTCAGTATACAAATGTAAATAATCACAGATGAGAATGTACTTAGCTGTATTTTCAAATAAGTAATCTTCCCCCCTTTTGTAGGACTTTAAAACTAGGCATCAATGAACCTGTTTTTCCTATTATGCCTGGAATTTAGTCATGATACCTTGACTCATTCCATCATATTTCAAGAGGATTCAGAGTGCTAGAAATTATTTTGGTAGCCTGTAACACACGGCAACACTGGTCCTTGGGCCTATGATGACCCACAGATGACTCAGTATAGAGTTCATTGCTAATTATAAATTACTAGTGAATCTTTTTGATATTTTAAGCTCTAGTGGGAAAAATCTGGCCACTTTTGTGTTTTTATGAAGGCCATGGAATAAAAGGATCCAAAGATTTAAATATTTTTATCTAATATTTTGATTGTTTTCTTAACTTTCTCCTTAAAACATTCAGTAGTGATAAAGATATAGAAACTGCACTGTAGGAGAATTGGAATATTTAAGGCTGGTTGACATTTTTTATTTTCATTTTATATCTTTTGTATAGCTCTACAAGGCAGTGTTTTGTAATTTGGTTTCATTATGAAGATCCAGTACTTGGCAGCCATAGTTTAGACAATATTGTTCAGTGCTGTTTGCTTGCATGTTAACAACAAAACCTTTTAGAGGACCCACAAATCATGATATTGAACACAGTTCCGAGGCATTCAGAGCATCAGAGCAAGTACCATGGCAATACATGTGTAGACTGTTGGAGATGTCCCGGGCCAATTTCAAGAAAGAAAACTGTAAATACTAGTTCTACTTGCTCTGAAATTATGAGTTTATGCGTTTTCCCAGCCCTCCGAATCACTGACTGGGGCGTTTTGTGCCCCAGCAATAACTGGCAGCATGGCATACCTGCAGTACCCCTTACAATATTAAAGCAAAGTTTTTATTCTAAAACAGAATAAAACTGTTCAATAAAAAA

Publications

PMID - Link Title