Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DPF2P1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:131182821-131185479  UCSC
Coordinates (T2T) chr6:132377262-132379920  UCSC
Coordinates (hg19) chr6:131503961-131506619  UCSC
Strand -
Parental Sequence NM_006268.5
Parental seq. overlap 2249 bp
Parental seq. overlap (%) 60.3%
Genomic Region Intragenic (AKAP7)
Retrocopy Summary DPF2P1, located on chr6:131182821-131185479, is a retrocopy of the parental gene DPF2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DPF2
Full Name double PHD fingers 2
Also known as CSS7|REQ|SMARCG2|UBID4|ubi-d4
Coordinate chr11:65333840-65354262
Strand +
Gene summary The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DPF2P1
Bonobo Pan paniscus DPF2P1
Gorilla Gorilla gorilla DPF2P1
Orangutan Pongo abelii DPF2P1
Gibbon Nomascus leucogenys DPF2P1
Green monkey Chlorocebus sabaeus DPF2P1
Crab-eating macaque Macaca fascicularis DPF2P1
Rhesus Macaca mulatta DPF2P1
Baboon Papio anubis DPF2P1
Golden snub-nosed monkey Rhinopithecus roxellana DPF2P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DPF2P1
CTGTGGTGGTGAATGCAATGAAGTTCCTTGGGAGCAGTACTACAAAGATGCCATGGAGCAGGGCCACAATTACAATGCCCACCTCTGTGCTGAGCACAGCATGTGCCTGCCTTTCTTGGCCTCACAGACTGGAGTAGCCCAGAACAATTATTACAGCTGGATGAAGAAGTAACCAGGTTCTAGGATTGGCCTCTGGACAACTACTCGTACCCTGCCCAGCACTGGCGGAAAAAGCGGTGAGCCCACCCCTGTGAAGATCCACAATTTTTCTTCCCACCTATTAAGCCAGACACAGACCCCACCCTGAAGAAGGAGGGGCTGATCTCTCAGGACAGCAGCAGTTTAGAGGTTCTGTTGCACACTGACCCCCTGGGGAAGCGAGGTACCCCAGATCCCCGAGTTGATGATGACAGCCTGGGCAAGTTTCCTGTGACAAACAGTCAAGCACGAAAGCGGATCCTAGAACCAGATGACTTCCTGGATGACCTCGATGATGAGTACTGTGAAGATGCTCCCAAGCATCGGGGAAAGGGGTAATCCAAGGGTAAAGGTGTGGCAGTGCCCATAAGGAGCTGGATGCTTCCAACCTGGAGGACCAGGATAAGCCCTATGCCTGTGACATTTGTGGAAAACGTTACAAGAACCGACCAGGCCTCAGTTACCACTATGCCCACTCTCACTTGGCTGAGGAGGGCGAGGACAAAGAAGACTCCCAACCACCCACTCCTGTTTCCCAGAGGTCTGAGGAACAGAAATCCAAAAAGGGTCCTGATGGATTTGCCTTGCCCAACAACTACTGTAACTTCTGCCTGGGGAACTCAAAGATTAACAAGAAGATGGGACAACCTGAGGAGGTGGTGTCCTGTTTCGACTGTGGCTGCTCAGGGCATCCATCTTGCCTCCATTTCACCCCCATGATGATGGGGCAGTGAAGACATACTGCTGGCAATGCATCGAGCACAAATGTTGCGATATCTGCGGCACCTCTGAAGATGATGACCAGCTGGGCTTTTGTGATGCTGCGATCATGGCTACGAAATGTACTGTCTCACTCCGTCCATATCTGAGCCCCCTGAAGGAAGTTGGAGGTGCCACCTGTGTCTGGACCTGTTGAAGGAGAAAGCTTCCATCTACCAGAACAAGAACTCCTCTTGATATAGCCACCCCCCTGCTCCCCGACATATCTAAGGCTGTTTCTCTCCTCCACTTCATTTTTCATACCCACCTTTCCCTTCCTCCTCCTCTCCTTCACAAGTCCAGAGAACCTTGGGGTGGTTGTTCTAGCCTGCCTTTGGCAGCCACAAGCTGATGTGGCAGCTCTGGCCACCTCTGGCCCTAGGCCCTCAAGGAGAAAGGAGCAACACACTGCCCCAAGGCATACCTGTGGGCCCAGTTTCTCTCTGCTCTCCATGAAATGCATTCATTCTGCTTGCCTTGGGCCCAGGCCCTGGTCATCACAGGGTTCAAACAGTGTCCTCCTAGAAAGAGTGGGAGAGCAGCTCACTTCTCTCTCTGTTCTGCCTCCACTCTGGTCTCCAGAGTTTTCCCATCCCCCAGAGGCGAGCCAGGCCAGAGCCTCTGCCCAAGGCAGCTGGTAGCGAGCAGCTGAGGCCACAGCCACAAGGAGCTTTCCATGCCCCTGTGTCACTTAGCCTCACCTCCTTCCTCCAGAGTGGCTCTCTGCAGCCCTCTGTTCCTGCTACGTAGGATTCTTTGCTGGAGTCAGGATGTTCTCGGTCACCCTCCTGGCTCTGCCCTGTCCCAGTCCACCCCACCCCAGGGGGAGCAGCAGCTTCACCTTGTGCTTCCCAGTGCTCTCCAGGCTCACTCTCATGGGCGGGCTCCAGTGACTAAAGCATTCCCCACCCTTGGAATGTCTCATCTTCTACCTCTCTTCTTATTCATTTTGGTTTTGTGGGGAGAGGGGAAGGATCAGGGGGCCAGGCCAGCAGCTCAAGGGCCACAGGGAGATGGGTAATGTGCCTGTTTTTTTAACACAACAAAAAAGCCTACCTCCAAAATCCCCTTTTTGTTCTTCCTGGACCTGGGCATTCAGCCTCCTGCCCTGAACTGAATTGGGAGCCTTGCCACCTGCCCTGTGTATCCTGGCTCTCAGCTCATGGGGAAGCCACACAGACATCCCTTTCTTCCCCTGCATGCTCGCTAGCAGCTGGTAAGGTCTTCACACTCTGATTCCTCAAGTTTTCTGCTTAGTGGCACTGACATTAAGTAGTGGGGGGCCAGTGCATGCCAGCATACCCTGGAGTAGCCTTCCCCCTTGGCCGCAGGCAGGCCCTAACTCACTGTCACTTTGAAGTTGTCTTTTTTTTCCTTTCGTTAGTTCCTGTATTCTAAACATCAGTAAACATAAACGTTTTTACACAGAGCCCTCTGCTGGATGGTTTATCTCCTGCCTCTCTCCATTAAGAAGGCCTTTTCATCCTAAGATTTCCATGAc
>NM_006268.5
GGGGCTTCTCGGCCCGAGGCAGAGGAACAGGGAAGATGGCGGCTGTGGTGGAGAATGTAGTGAAGCTCCTTGGGGAGCAGTACTACAAAGATGCCATGGAGCAGTGCCACAATTACAATGCTCGCCTCTGTGCTGAGCGCAGCGTGCGCCTGCCTTTCTTGGACTCACAGACCGGAGTAGCCCAGAGCAATTGTTACATCTGGATGGAAAAGCGACACCGGGGTCCAGGATTGGCCTCCGGACAGCTGTACTCCTACCCTGCCCGGCGCTGGCGGAAAAAGCGGCGAGCCCATCCCCCTGAGGATCCACGACTTTCCTTCCCATCTATTAAGCCAGACACAGACCAGACCCTGAAGAAGGAGGGGCTGATCTCTCAGGATGGCAGTAGTTTAGAGGCTCTGTTGCGCACTGACCCCCTGGAGAAGCGAGGTGCCCCGGATCCCCGAGTTGATGATGACAGCCTGGGCGAGTTTCCTGTGACCAACAGTCGAGCGCGAAAGCGGATCCTAGAACCAGATGACTTCCTGGATGACCTCGATGATGAAGACTATGAAGAAGATACTCCCAAGCGTCGGGGAAAGGGGAAATCCAAGGGTAAGGGTGTGGGCAGTGCCCGTAAGAAGCTGGATGCTTCCATCCTGGAGGACCGGGATAAGCCCTATGCCTGTGACATTTGTGGAAAACGTTACAAGAACCGACCAGGCCTCAGTTACCACTATGCCCACTCCCACTTGGCTGAGGAGGAGGGCGAGGACAAGGAAGACTCTCAACCACCCACTCCTGTTTCCCAGAGGTCTGAGGAGCAGAAATCCAAAAAGGGTCCTGATGGATTGGCCTTGCCCAACAACTACTGTGACTTCTGCCTGGGGGACTCAAAGATTAACAAGAAGACGGGACAACCCGAGGAGCTGGTGTCCTGTTCTGACTGTGGCCGCTCAGGGCATCCATCTTGCCTCCAATTTACCCCCGTGATGATGGCGGCAGTGAAGACATACCGCTGGCAGTGCATCGAGTGCAAATGTTGCAATATCTGCGGCACCTCCGAGAATGACGACCAGTTGCTCTTCTGTGATGACTGCGATCGTGGCTACCACATGTACTGTCTCACCCCGTCCATGTCTGAGCCCCCTGAAGGAAGTTGGAGCTGCCACCTGTGTCTGGACCTGTTGAAAGAGAAAGCTTCCATCTACCAGAACCAGAACTCCTCTTGATGTGGCCACCCACCTGCTCCCCGACATATCTAAGGCTGTTTCTCTCCTCCACTTCATATTTCATACCCATCTTTCCCTTCTTCCTCCTCTCCTTCACAAATCCAGAGAACCTTGGGGTGGTTGTGCCAGCCTGCCTTTGGCAGCTGCAAGCTGAGGTGGCAGCTCTGACCACCTCTGGCCCCAGGCCCTCAGGGAGAAAGGAGCAACACACTGCCCCTAGGCGTGCGTGTGGCCCAGTTTCTCTCTGCTCTCCATTAAGTGCATTCACTCTGCTTGCCTTGGGCCCAGCCCCTGGTGATCACAGGGTTCAAACAGTGTCCTCCTAGAAAGAGTGGGAGAGCAGCTCACTTCTCTGTGTTCTGCCTCCCCTCTGGTCTCCAGAGTTTTCCTGTCCTCTAGAGGCAAGCCAGGCCAGGGAGCTGGGAGCGAGCAAGCTGAGGCCACGTCCACAAGGAGCTTTTCATGCCCCTGTGCCGCATAGCCTCACCTCTTTCCTCCAGAGTGGCTCTCTGCGGCCCTGTGTTCCTGCTACAGAGTGTTCTTTTCTGGAGTCAGGATGTTCTCGGTCACCCTCCTGGTTCTGCCCTGTCCCATTCCACCCCACCCCAGGGGGAACAGTAGCTTCACCTTGTTATTCCCATTGCTCTCCTGGCTCACTCTTACGGTCGGTCTCCAGTGACTGAAGCATTCCCCACCCTTGGAATTTCTCATCTTCTGCCTCCCTTCCTACTCCTTTTGGTTTTGTGGGGAGAGGGGAAGGATCAGGGGGCCAGGCCAGCAGCTCGGGGGCCACAAGGAGATGGATAATGTGCCTGTTTTTTAACACAACAAAAAAGCCTACCTCCAAAATCCCCTTTTTGTTCTTCCTGGACCTGGGCATTCAGCCTCCTGCTCTTAACTGAATTGGGAGCCTCTGCCACCTGCCCCGTGTATCCTGGCTCTCAGCTCATGGGGAAGCCACATAGACATCCCTTTCTTCCCTTGCACGCTCGCTAGCAGCTGGTAAGGTCTTCACACCCTGATTCCTCAAGTTTTCTGCTTAGTGGCACTGACATTAAGTAGTGGGGGGACAGTCCATGCCAGGACACCCTGGAGTAGCCTTCCCCCTTGGCCGTGGGCAGGCCCTAACTCACTGTCGCTTTGGAGTTGAGGTGTCTTTTTTTTTTCTTTCTTTAGTTCCTGTATTCTAAACATTAGTAAAAATAAATGTTTTTACACAGAGCCCTCTGCTGGATGGTTTATCTCCTGCCTTTCTCCATTAAGAAGGCCATTTCATCCTAAGATTTCCATGATGgtggtttttttttttaatgttttgaaatacagcttttttccccccaaattaaaatttttttgtggaaccccaatatgtaaagcgaatataaaattggttattttgttttgttacataaattcaagtttataacaattctttgttataaagaacaatgaagctgttttgatcaatacaaaatttgggttaaaatcaactttaacatctatttttatgtttcagttgatttggagaattctcctagtcttggatacatagatggaagtgatgacaggtttataacagttgaccttgcaatctcagacatttaaaacaggaccagaagtttATATAAATATAATTAATAAGCAAACTAATGACATCACCATGGGACACACACAAAAGTTCTTGCAGGAGCAGGGTCTGTGTGGCTTCAGTTGCCTGCAGCGCTCCCAGGCCAGAGCAAGTGCTCTAGGATCTGAACTGCCCGCAGTGCAGCCCTGCAGCCTTTCCCAGGGCACGTTGATGTGCACACAGTTTCCCTGAAGGCAAAGTGAACATGTGGAGAGCTTACGTGGCAGCGCGTATGTCTTCAGTGTGTGTTTTAGAAGTCCAACTGTTGTTTTTATGTTTTTAAAGGAAAGATTTGAATCAAGCAGTTATGGGCCCCCTGAAGTATCCTTTTTTCTAGAACATTCTGAAAGTCATCCTTGCCTATGGGAAGCCTAGGCCGGCCTGCACTGTTATGTTCAATAAATAAGCAGGGTGCTCTGGGCTGGGGATTGTGTGAGGAGCAGAGCGCAGCCCGTCCTCATGCTTTTCCACTGAAGTAGGCCAGGCAGAGAGGGAGTACAGCAATGGATGCGCTTTGGCAGCTGAGTAGTCCGAGAGCCAGAAAAGAAATGTGGAAAATAAGAACGCTGTAGCAGGCCTAGGTGAGGAAATTTAGGAAGGGTTTGCGGGAGGTAGGATTTGAGATGGGTCTTGGAGAGTTGGACAGTGTCAGCCGGTAGGACGGGGGTGCGGACGGAAGCCTGTGAGGAAGGCAGAGGATGCGGAGCTGTGAGCGGAGGGAGCAGCGAGGCTGGAGAGCAGCTGGGCTGCGGGTCAAGACGTCTGCGTTTAATTCGGGACTGAAGGTTAGCAGGGAAGGGAACGATGCCAGATCTTGAGTTTAAGAACTTGAATCTTGTAAAGTACCAAATCTAATAAAATACTCGTCCTAAATCA

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