Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name FAM8A6P
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:134603141-134604239  UCSC
Coordinates (T2T) chr6:135791384-135792482  UCSC
Coordinates (hg19) chr6:134924279-134925377  UCSC
Strand -
Parental Sequence NM_016255.3
Parental seq. overlap 1015 bp
Parental seq. overlap (%) 21.4%
Genomic Region Intergenic
Retrocopy Summary FAM8A6P, located on chr6:134603141-134604239, is a retrocopy of the parental gene FAM8A1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name FAM8A1
Full Name family with sequence similarity 8 member A1
Also known as AHCP
Coordinate chr6:17600302-17611715
Strand +
Gene summary Predicted to be involved in ubiquitin-dependent ERAD pathway. Part of Hrd1p ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FAM8A1P2
Bonobo Pan paniscus FAM8A1P2
Gorilla Gorilla gorilla FAM8A1P2
Orangutan Pongo abelii FAM8A1P2
Gibbon Nomascus leucogenys FAM8A1P1
Baboon Papio anubis FAM8A1P1
Golden snub-nosed monkey Rhinopithecus roxellana FAM8A1P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FAM8A6P
GGGGCCTGACCTGTGGGCAGCTGCTGGCGTCAGCACCCTTGCTCCAGTCGTGGGCCTGGGACACCAGGCTTCTCATGTGCAGGCGTCTGAGCTGCTCCAGTGAGGAGGGTAGGATCCATGGCCCCTTGGTGAAGCCTGAGCGAGACTGGGCGAGAGGCAGGGAGAGAATATGTTATTCCATCCTTGGGCCACAGATTTATGGCAAGGATGGTGGATTTCTTTATTCTCTTTTTGTAAAGGCAACCATTGTCTTAAGCATTATGCACCTTAGTGGGATAGAGGATATCTCTTTGCTATGCATTACATATTGGAATAAATAGATGAAGGCACATCAATGGAAGACTTGCAGAAAATGATGGTTGTGGCTCTTATATACAGATTATTAGTTTGTTTCTATGAGATAATTTGCATTTGGGGAGCAGGTGGAGCTACCCCAGGGAAGTTCCTGCTGGGGCTTCGAGTTGTGACATCAGTGCTTATTGCACTAAGTTGGGTTTTAGTGATTCCTTCCTCAAATGTTAGTATTACAACGTCCACTATACGAGCTTTGATCAAGAATTTTTTGATTGCTTCTTTTTTCACTGCTTTCATCACACTGCTGTTTTTTCAGCATAATCGAAAAACCTATGACATTGTAGCAGGAACCATTGTGGTAAAAAGAAATGGGGTCAGATGATGCCCCCTAAAGCCCTGATTTCCACACACTGTAATGACAAGACTAAATCATGTATCAAGGCCATCAGTACCCTGGGTTACACTAATTGATGCTTTAGAAATTAAAGCAGTCACTCCAGTGTGATGCAGGTGACTACTCTGAAAGTATTGATTTTGCTTGAATGCCAAAGAACTTTTCCAGAAGAAAAACCTATTTAAATTCAAGTATTAAAATTTTTAGATCAAAAAGGCAAATTATTTTACAAACAATAGACAATATATATTTTCTTAAGATCTAAGAATTTGCTGAAAGCATTTTCAGCTTTGAAATCTCCAAATGAAATTTTAAAATTTATTTTGGTTTATCCCAGAATAATGGAAAATGTCCAGTTGTGTTTTGTAAACACCTATGTAACTCATCTTTTAGTTCACa
>NM_016255.3
GTTGACGCCTGCGGTTGCTGCGGTGGTGACGGGGCTGTTGGGGAGGGGCCATTGGGGGAGGGAAACGGAGCAGTGACAGGTATCCCAGAGGGTGCTGCTGAGGCGACGATGGCCGAGGGGCCCGAGGAAGCCCGAGGCCACCCTCCCGGGCAGGACGATGGCGGAGGGGACCACGAGCCCGTCCCTTCCCTGAGAGGCCCTCCTACCACCGCCGTCCCATGCCCCCGCGACGACCCCCAGGCCGAAccccaggccccgggccggcccacagccccgggcctcgcggcTGCCGCCGCAGCCGACAAATTGGAGCCGCCGCGCGAGCTCAGGAAGCGCGGGGAGGCGGCCTCCGGCTCCGGTGCAGAGCTGCAGGAGCAGGCGGGCTGCGAGGCGCCCGAAGCCGCGGCGCCACGAGAGAGACCAGCTCGGCTGAGCGCCCGCGAGTACTCCCGGCAAGTGCACGAGTGGCTGTGGCAGTCCTACTGCGGCTACCTCACCTGGCACAGCGGCCTGGCCGCCTTCCCAGCCTACTGCAGCCCCCAGCCCTCCCCGCAGAGCTTCCCTTCGGGCGGCGCTGCAGTCCCCCAGGCCGCGGCGCCGCCGCCCCCGCAGCTGGGCTATTACAACCCCTTCTACTTCCTGAGCCCCGGGGCCGCGGGGCCTGACCCGCGGACAGCTGCCGGCATCAGCACCCCTGCTCCAGTCGCGGGCCTGGGACCCCGGGCTCCTCACGTGCAGGCGTCGGTCCGGGCCACTCCAGTGACGAGGGTAGGATCCGCAGCCCCTTCGCGAAGCCCGAGCGAGACCGGGCGACAGGCAGGCAGAGAATATGTTATTCCATCCTTGGCCCACAGATTTATGGCAGAGATGGTGGATTTCTTTATTCTCTTCTTTATAAAAGCAACCATTGTCTTAAGCATTATGCACCTCAGTGGGATAAAGGATATCTCTAAGTTTGCTATGCATTATATAATAGAAGAAATAGATGAAGACACATCAATGGAAGACTTGCAGAAAATGATGGTTGTGGCACTTATATACAGATTATTAGTTTGTTTCTATGAGATAATTTGCATTTGGGGAGCAGGTGGAGCTACCCCAGGGAAGTTCCTGCTGGGGCTTCGAGTTGTGACATGTGATACATCAGTGCTTATTGCACCAAGTCGGGTTTTAGTGATTCCTTCCTCAAATGTTAGCATTACAACGTCCACTATCCGAGCTTTGATCAAGAATTTTTCAATTGCTTCTTTTTTCCCTGCTTTCATCACACTGCTGTTTTTTCAGCATAATCGAACAGCTTATGACATTGTAGCAGGAACCATTGTGGTAAAAAGAAATGGGGTCAGATGATGCCCCCCAAAACCCTGATTTCCACACACTAAGACTAAATTATGTATCAAGGCCATCAGTATCCCTGGGTTACACTAATTGATGATTTAGAAATTAAAGCAGTCACTCCAGTGTGATGCAGGTGACTACTCTGAAAGTATTGATTATACTTGAATGCCAAAGAACTTGTCCAGAAGAAAAACCTGTTAAATTCAAGTATTAAAATTTTTAGATCAAAAAGGCAAATGATTTTATAAACAATGGACAATATATACTTTCTTAAGATCTAAGGTACTTTCTTAAGATCTAAGAATTTGCTGAAAGCATTTTCAGCTTTGAAATCTCCAAATGAAACTTTAAAATTTATTTTGGTTTATCCCAAAATAATGGAAAATGTCCAGTTGTGTTTTGTAAACACCTATGTAACTCATCTTTTAGTTTACACTTCCTGGGGAAATTGTCTTTGGTGTTTAGAGGAGGGAATGAGAACACAAATTGGATAATCCACTGTCTCCCATCCCAGGAGGTGGTGAGTTGGCTACAAGAGAAAGGGACAAGTGAGGCAGGCCTAGCAGTTCCCTTACCTGAAGTTTTCAAATCCATACTGCAGTTCCCTCTCGTAATGATGTAACTTTACAACTATTCTTAATGCTTGAACATGTATTTAGGGGCAAGTTTCTCATGATGATGAAAAAGTATCAAGTCATATTGCTATGTTAATTGGTTTTTTTTTTTAAAAGGTAAGTTAGTGATTACTGTTAATGGTGGGGGAGTAAGTTTTCACTGTAAATTGAACTTATAATTTATGTGCAAGTGTTTTCAGTGCCCTGAATCAAACTATAAATGTGGGGAGAAATCACCTCCATCAAACAGTTGCATATTTACTGTAAAAGTATTCCCAGTATGTGTGCAGCATGAAGAAAGTATTAGTGCTTCTCAGTGTTCTCAGTGTAAATTCTATTTATATACAGCATATTCACATACTACTTTCCTTATATTTTATATAGTTCTATGACTGTTGAAACATCAAGGAGTTAAAAAAATCTTAATATTTCATGATTAACTCTAAGTACTATTAATTAATAGCTTGCGAAATATTAGCAATTTTCCCATTATGGACTATTCTCTCTAAAGCAAGAGAGACTAGCATTCCCAGACATCATTCTAGGGTCTTTAAGCTCATTTTGGGTCTGCTAAAGTTTGGGGGGAAATGTTACGCAAAGTGATACTGTGTATGTTGCCATTTTGCTTTATTCTTCTGTTGAAGCAAAATTGTGGGGTTTTATTATGTGTGTGTGCTTTTCCTAGATGTCCCAGTTAGCTGTGCTGAGATATACCTGTACTATTTATGGTTTAAGTTTTGATTCTTAGGTATTTTCTCCAGCTCTGACATTGTTTTCCAAAGACACACTAAACTGCATTGCACAGTTCAAAATTTGATTACTTAAGGGATCAATCTAGGTGGTGTTCTTGGTCTTAAATTTAACAGCAAACACAGCACATATCTATTATCACTATATTAATTTTCAAAGGTTTTTCTTTGACGTTTAAAACTGTGACAACAGATATTCACATTTGATTATAGAAACTTAATGTCTATTAATAATTTTAGTACAAAATTTCATAAACCGTGTTTTTCAAAATAAGTTTATGTCAAATCCAGCTTCCCAGAAACACTAATAATTAAGTACATCAATGTACTAAATAAATCATTCAGTTGCACCCATGGGGAAGATTGTGTTACTGCCCTTCACAGTGAAAAAAAGAAAAATCTTTCATTTTTAAAATTAGGAGATGTTACGTAACTTGGCACTTTAGTAGTGTATACACTAGCATTAGTTTATACACCACTTTTGCCGCTGGGGAATTCAAGTTGAAATGTCCCTCAATCATATAGGTCTGGAATACATCTTTCATTCATAATTTCTGCTCAGATAATTGAATAGTTTGCCATCGAGATTATTTTCATTTATACTATAAAACAAAAGCAAACTAGTCCAGTTTAATTTTTTGTACTTAGAATATTGCACATTTTCTATATATGAGTTATTCAGATTAGTATCTATGTAGGTTCAGTCAGATCCAACCATGGATTCGAGGTATTATACTGTATAACCCTACAAAATACATAGAAGTATTATTTGCCTTCATAATAGAACCCAAGAGTCTGTTTCAATTTATGAATTCAGTATTTGCACCGAGATTTTGATTCCCAAAGTTTGGAAAAAAATGACAAAACAACGAGGGAAGAAGGAACCAGACCTTAGTGCCACATATTTTTCTCTTGGGGTTGTAAGGTAGTCTCCTGCTTTCCAGAACACTTTATTATATTTCACTTATAGACCTGATTTTCTGTGTCAAAGTATAATTCTCATGCTGAAGCTGTAGCCTAAAAAGCCAAAAGAAAGTTGTCTTCATTGTACAAACATATTCATCACTTTAACAATAAGGGAACAAAATTTAGTATTCAAGCTGAGTGAGAATACTGTTTCAATGAGCATGTCCCTAAGATAAACCAGAATTGGCAGTTAATTTAGGCGTCTAGAAAATCTCAGTTCCCACCAGTAAAATTATCCTGAGTAGCTAATGCACCTTGAGAAAAATCTGGCATACTGAATAAATAACATTAACTTGGGAGCCAAGAGCTGGGTAAGCCTTACCTTTAGACTACTCTGTGACTACAGAAATAAAGCCAGCACTTTTGGAACTAATAAGCCTTCACTTGTCAGTATCATAAAGAGTATTGCCCAACTGAACTTTGCTCCCACTGGTTTAATAGTTACTTATTTCTGCCTAAGCACTCACCTTCCGATTTTACCCAAGTATATATATAGGATAGAAAAAAATGCATTATATTTGAGAGCTACTTCGCCCAAATTACAAAATGAGTGTTTTTAGATTCAAGTGACAGTAAAAGGATTTGTTCCCTTCAGTGACTTGAGTGTTTTAGTTATGCATAAGTATTTCTAGCAAAGGAAGGGTAGAAAGGAATTGAAAATTAATTTACACTAGTTGCTACTTGGGAATAAAGGGCTTTTTGAGGGGGGTATGGATATTAAATGTTTTCGTTATATACTTATCCCTATTAAAACAGGCAGTTGTTTCTTTGAATATGCCTAAATAACAGTATTCTTAAAATCTGACAGACAAGTAACATGTCAATTACTTGATATTCCTTGTCTCCAGTACCACAGGCCACTCTTGACATCCCATGTTTGCCTGGATAAAGTTCCTCATTTCAAACAGTATACATACTTCTTTGCAGTTCATTATAGTAAGGCTTAACCTGTAAACAGTATCTGATGGCCCACCTATAAATAAAATTCAGCATTCTATTTTTAATAATTTGTATGCCACCAATTTGTATTATTTGTCTCAATAAATACTTAGTCATCAA

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