Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MTCH1P1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:138649474-138650975  UCSC
Coordinates (T2T) chr6:139838017-139839518  UCSC
Coordinates (hg19) chr6:138970611-138972112  UCSC
Strand -
Parental Sequence NM_014341.2
Parental seq. overlap 1375 bp
Parental seq. overlap (%) 60.7%
Genomic Region Intragenic (NHSL1)
Retrocopy Summary MTCH1P1, located on chr6:138649474-138650975, is a retrocopy of the parental gene MTCH1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MTCH1
Full Name mitochondrial carrier 1
Also known as CGI-64|PIG60|PSAP|SLC25A49
Coordinate chr6:36968135-36987171
Strand -
Gene summary This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Oct 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes MTCH1P1
Bonobo Pan paniscus MTCH1P1
Gorilla Gorilla gorilla MTCH1P1
Orangutan Pongo abelii MTCH1P1
Gibbon Nomascus leucogenys MTCH1P1
Green monkey Chlorocebus sabaeus MTCH1P2
Crab-eating macaque Macaca fascicularis MTCH1P1
Rhesus Macaca mulatta MTCH1P1
Baboon Papio anubis MTCH1P1
Golden snub-nosed monkey Rhinopithecus roxellana MTCH1P1
Marmoset Callithrix jacchus MTCH1P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MTCH1P1
ATGTGCTGGGGAGGAAGGTCCTCTATCTGCCAAGCTTCTTCACCTATGCCAAATACATTGTGCAAGTGGATGGTAAGATAGGGCTGTTCCAAGGCCCGAGGCCCCAGCTGATGTCCAACGCCCTCTTCACTGTGACCTGGGTAGCATGAAGAAGGCTTTCCCTGTAGATGAGATCTAGCAGGTTTCCAACAAGGGTGATATGAAGACTTCCCTGAAGAAAGTTGTGAAGGAGACCTCCTATGGGATAATGATGCAGTGCGTGTCCCGCATGTTGACCCACCCCCTGCATGTCATCTCAATGTGCTGGATGGTCCAGTTTGTGGGATGGGAAGCCAAGGATAGTGGCGTGCTGAGCTCCATTGGGAAGCTTTTCAAAGAGGAAGGGCTGCTGGAATTTGTTGGATTAATCCCTCACCTCCTGGGTGATGTGGTTTTCTTGTGAGGCTGTAACCTACTGGCCTACTTCATCAGTGCCTACCTGGTGGATGACAGCCTCCACCAGGCCCTGGCCATCCGGAGCCACACCAAATGCTTGACAGGGATTGCAGTGAGCATGCTGACCTACCCCTTCCTGCTAGTCGGCGACCTCATGGCTGTGAACAACTGTGGGCTGCAGGCTGGGCTCCCCCGTTACTCCCCGGTGTTCAAATCCTGGATTCACTGCTGGAAGTACCTGAGTATGTAGGGCCAGCTCTTCCAAGGCTCCAGCCTGCTTTTCCACTGGGTGTCATCAGGATCATCTTTCACCCTGGAGTAACCTGAATCATCTAAAAAACACAGTCTTAACCTGGCCACCATGAGTGAGGCCTGACCATCTCGGGATACCTGCAAGATGACTCCAACCCAACAACAACCAGATGTGCTCCCGCCCAGCCGGGCTTCAGTTTCCATATTTGCCATGTGTCTATCCAGATGTGGAGTTGGGTGGAGGTGAGGCTGCACCCAGTGGATTGGGTCACCTGCCAGACCTGGGAAAGGTTGGGAGAAATGGGGAGTTGGCAGAATCCCCATACCTCCTGGATTTGTTGAGTCTGTCTTGTGCAGAGGGCTGGAGAATGGCTCGTGGGGGCCCAGGTTGGATGGGGAAAGGATAATGGGGTCAGAACCCACCCTATCTACCCCTCCAGTCAGCCCAGAGCCCATCCTGTAGGTCAGCTGGGAGCATCATTCTCCTTCTTCGTAAATAGGGCGTGATCCCCTGGCACACGGCCACCATCATGTCTAGGCCTATGCTGGTAGGCAAATGCTAGGCTCTGCCTGCGTTTTTCTCAACACTACTCTTTTTATATGAGGGCAGCACCTTCCTCTGAATGGGAAATCATGTGACTACTCAGAATGTGTCCTCCTCATCTAATGCTCATCTGTTTAATGGCGATGCCTCACATATAGGATCTGGTTACCTGTGCAGTTGTGAATACCCAGAGGTTGGGCAGATCAGCGTCTCTAGTCCTGTCCAGTTCATAGTAAGATTTGACCCCATCTCCTGCAAATAAATGTATTGA
>NM_014341.2
GCAGAGAAAACTCCCGAAGCCAGGGAGGTGGCTTGGAAGCGCCTCAGACCATATTGGGGACGTCTGGCAGCCAGAGGCGCCGAACCCCGCCCCCGCGTGCTCTGGGCATCCCGGGGGAGCGccccggcctgcggctgccgccacagctcccgagcccggggccccggctgcccgccaccattgacccccggcccgcagcccAGTGTCCTGCTAGGCCTCCAACCGGCCGGGGAGCCACATCCGGCGTGTCCCACCCGCCGCACCACGCTCCCGAGCTCCCCCGCGGCCTGGAGTGGTGCGCCCCGGCCCCGCCCCCTGACGCCGGTGAGGGGGCGTGGCCCCGTCACGTGACGGGGAGTGACCTCGCCGCCGGGCGCCATGGGAGCTTCGGACCCGGAAGTGGCGCCCTGGGCTCGCGGCGGTGCCGCGGGGATGgcgggagccggagctggagccggagctcgcggcggagcggcggcgggggtcgaggctcgagctCGCGATCCACCGCCCGCGCACCGCGCACATCCTCGCCACCCTCGGCCTGCGGCTCAGCCCTCGGCCCGCAGGATGGATGGCGGGTCAGGGGGCCTGGGGTCTGGGGACAACGCCCCGACCACTGAGGCTCTTTTCGTGGCACTGGGCGCGGGCGTGACGGCGCTCAGCCATCCCCTGCTCTACGTGAAGCTGCTCATCCAGGTGGGTCATGAGCCGATGCCCCCCACCCTTGGGACCAATGTGCTGGGGAGGAAGGTCCTCTATCTGCCGAGCTTCTTCACCTACGCCAAGTACATCGTGCAAGTGGATGGTAAGATAGGGCTGTTCCGAGGCCTGAGTCCCCGGCTGATGTCCAACGCCCTCTCTACTGTGACTCGGGGTAGCATGAAGAAGGTTTTCCCTCCAGATGAGATTGAGCAGGTTTCCAACAAGGATGATATGAAGACTTCCCTGAAGAAAGTTGTGAAGGAGACCTCCTACGAGATGATGATGCAGTGTGTGTCCCGCATGTTGGCCCACCCCCTGCATGTCATCTCAATGCGCTGCATGGTCCAGTTTGTGGGACGGGAGGCCAAGTACAGTGGTGTGCTGAGCTCCATTGGGAAGATTTTCAAAGAGGAAGGGCTGCTGGGATTCTTCGTTGGATTAATCCCTCACCTCCTGGGCGATGTGGTTTTCTTGTGGGGCTGTAACCTGCTGGCCCACTTCATCAATGCCTACCTGGTGGATGACAGCTTCAGCCAGGCCCTGGCCATCCGGAGCTATACCAAGTTCGTGATGGGGATTGCAGTGAGCATGCTGACCTACCCCTTCCTGCTAGTTGGCGACCTCATGGCTGTGAACAACTGCGGGCTGCAAGCTGGGCTCCCCCCTTACTCCCCAGTGTTCAAATCCTGGATTCACTGCTGGAAGTACCTGAGTGTGCAGGGCCAGCTCTTCCGAGGCTCCAGCCTGCTTTTCCGCCGGGTGTCATCAGGATCATGCTTTGCCCTGGAGTAACCTGAATCATCTAAAAAACACGGTCTCAACCTGGCCACCGTGGGTGAGGCCTGACCACCTTGGGACACCTGCAAGACGACTCCAACCCAACAACAACCAGATGTGCTCCAGCCCAGCCGGGCTTCAGTTCCATATTTGCCATGTGTCTGTCCAGATGTGGGGTTGAGCGGGGGTGGGGCTGCACCCAGTGGATTGGGTCACCCGGCAGACCTAGGGAAGGTGAGGCGAGGTGGGGAGTTGGCAGAATCCCCATACCTCGCAGATTTGCTGAGTCTGTCTTGTGCAGAGGGCCAGAGAATGGCTTATGGGGGCCCAGGTTGGATGGGGAAAGGCTAATGGGGTCAGACCCCACCCCGTCTACCCCTCCAGTCAGCCCAGCGCCCATCCTGCAGCTCAGCTGGGAGCATCATTCTCCTGCTTTGTACATAGGGTGTGGTCCCCTGGCACGTGGCCACCATCATGTCTAGGCCTATGCTAGGAGGCAAATGGCCAGGCTCTGCCTGTGTTTTTCTCAACACTACTTTTCTGATATGAGGGCAGCACCTGCCTCTGAATGGGAAATCATGCAACTACTCAGAATGTGTCCTCCTCATCTAATGCTCATCTGTTTAATGGTGATGCCTCGCGTACAGGATCTGGTTACCTGTGCAGTTGTGAATACCCAGAGGTTGGGCAGATCAGTGTCTCTAGTCCTACCCAGTTTTAAAGTTCATGGTAAGATTTGACCTCATCTCCCGCAAATAAATGTATTGGTGATTTGGAGTTTTT

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