Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SNRPB2P2
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr20). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:149111799-149112720  UCSC
Coordinates (T2T) chr6:150311663-150312584  UCSC
Coordinates (hg19) chr6:149432935-149433856  UCSC
Strand -
Parental Sequence NM_198220.3
Parental seq. overlap 817 bp
Parental seq. overlap (%) 35.3%
Genomic Region Intergenic
Retrocopy Summary SNRPB2P2, located on chr6:149111799-149112720, is a retrocopy of the parental gene SNRPB2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SNRPB2
Full Name small nuclear ribonucleoprotein polypeptide B2
Also known as Msl1|U2B''
Coordinate chr20:16730026-16742564
Strand +
Gene summary The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SNRPB2P1
Bonobo Pan paniscus SNRPB2P2
Gorilla Gorilla gorilla SNRPB2P1
Orangutan Pongo abelii SNRPB2P2
Gibbon Nomascus leucogenys SNRPB2P1
Green monkey Chlorocebus sabaeus SNRPB2P2
Crab-eating macaque Macaca fascicularis SNRPB2P1
Rhesus Macaca mulatta SNRPB2P1
Baboon Papio anubis SNRPB2P2
Golden snub-nosed monkey Rhinopithecus roxellana SNRPB2P2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SNRPB2P2
CCTATATGCCCTGTTTTCTCAGTTTGGTCATGTGGTGGACTTTGTGGCTTTAAAGACCATGAAGATGAGGGGCAGGGCTTTGTCATATTTAAGGAACTGGGCTCATCCACAAATGCTTAGAGACAGTCACAAGGATTTCCATTTTATGGTAAACCAATGCGAATACATATGCAAAAACAGATTTGGATATAATATCTGAAATGTGTGGCACTTTTGCTGACAAAGAAAAGAAAAAAGCCAAAACTGTGGAACAGACTGCAACAACCACAAACAAAAGGCCTGGCTAGGGAACTCCAAATTCAGCTAGTACCCAAGGAAATTCAACACCAAATCCTCAGGTCCTCGATTACCCTCCAAACTATATTTTATTCCTTAATAACTTACCAGAAGAGACTAATGAGATGATGTTATCCATGCTGTTTAATCAGTTCCCTGGCTTCAAGGAAGTATGTCTAGTACCAGGGAGGCATGACATTGCTTTTGTTGAATTTGAAAATGATGGGAAGGCTGGAGCTGCCAGGGATGCTTTACAGGGATTTAAGATCACAACATCCCATGCTATGAAGATCACCTATGCCAAGAAATAAAATTTGGGAGAGTCATCTTTAAAGGACTTGGTGTTATTTATAGTGTTTGTTTTGCTAACATTTGGTTGGGTCATTGTAATAGAGATTAGGGGAAGTGAAAGTGAAATTTTTGTGAAGGACTTAAATTATCTAGTATTTCTTTAGCCTTGGTGAATTATGAAATACGAAGGCCTTAATTTTGTACAATAAACTTTGATTTGTATTCTGTGATAGGCCTTAGATTATTTACTGTCTCTTTCTGAAGAATTTAACGCAAACATGGATATCAGACCAAATCATACAATTTATa
>NM_198220.3
CCTGCTTTTGGTTCTTACAGTAGTCGGCGTAGGCCTTAGATTTTTTACTGTCTCCTGAAGAATTTAACACAAACATGGATATCAGACCAAATCATACAATTTATATCAACAATATGAATGACAAAATTAAAAAGGAAGAATTGAAGAGATCCCTATATGCCCTGTTTTCTCAGTTTGGTCATGTGGTGGACATTGTGGCTTTAAAGACCATGAAGATGAGGGGGCAGGCCTTTGTCATATTTAAGGAACTGGGCTCATCCACAAATGCCTTGAGACAGCTACAAGGATTTCCATTTTATGGTAAACCAATGCGAATACAGTATGCAAAAACAGATTCGGATATAATATCAAAAATGCGTGGAACTTTTGCTGACaaagaaaagaaaaaagaaaagaaaaaagCCAAAACTGTGGAACAGACTGCAACAACCACAAACAAAAAGCCTGGCCAGGGAACTCCAAATTCAGCTAATACCCAAGGAAATTCAACACCAAATCCTCAGGTCCCTGATTACCCTCCAAACTATATTTTATTCCTTAATAACTTACCAGAAGAGACTAATGAGATGATGTTATCCATGCTGTTTAATCAGTTCCCTGGCTTCAAGGAAGTACGTCTGGTACCAGGGAGGCATGACATTGCTTTTGTTGAATTTGAAAATGATGGGCAGGCTGGAGCTGCCAGGGATGCTTTACAGGGATTTAAGATCACACCGTCCCATGCTATGAAGATCACCTATGCCAAGAAATAACATTTGGGATAGTCGTCTTTAAAAGACTTGGTGTTATTTACAGTGTTTGTTTTGATAACATTTGGCTGGGTCATTTTAATAGTTAGAGATGAGGAGGAGTAAAAGTGAAATTTTTGTGAAGGACTTAAATTATCCAGTGTTTCTTTAGCCTTGGTGAACTATGAAATACGAAGGCCTTAATTTTGTACAATAAACTTTTATTTGTATTCTGTGTATATAATGCTTTCTTGATTGACCCATCTCCCTATCATCAAATGACTTCTAGTCTAGAACACACTTAAGGTTTATAAACTTGTGTAATAGGATGCTTTTCTAGTGTTACTTTGGAGGAGCTAATTATACAACATCATTGAACCATTCAATAAAAGTTAAGTAAAATTAGATCACAGAAGCTAGTAGATGACTGTTGTATTAATGGTAACAATGATTGTTCTGGGTATTAGAAGAAAATGAGACCCAGGCAGGATCTAAATTTGATCTTTGTATCCTTTTAAGAAATGAATATATTATTTTGCTGCTAGTAGGGATTCCACAAGTTTTCTTCATTCAGTATTAAATAAAGGCTGTTCTTACTGTTTACTGAGAAAACAGAAAGGGAATGCTATCTTCACACTTTGCATTTAATGCTGTTTCCTTCATGAGGCAGGACTGTTCTAAGGTTAATATGCAATCTCTTTATTGAAAGACCTCCAGGGTAAAAATTTTTTGATCTATAGTCTCTTTTCCCCCTTAAGACAAATAGACTGATTAATAAAGAGTTGCCAGTGCTAAGCTTGCTACTTCTTTGTAATTCTTAAACACCAATGTTCAAATATTTCCAAAGCCCATTTTCTTTAGCTTTTGATTTATGTTTAAGGCTATTGATTCAGTCCTCTGCTGAGTAAACCATGGGTATCTCCAGAAGTGGACAATTTGTTTTTACAAGTATGGTACATATTAATAGTAACAACAACAAAAAAGAAAACAGTACTTATTTTTCTGGTGTTCCTGTTTTAGTATTCCTTGAACAAAACCTttatcacttggaatttttattgtctacttatggaaagacttttagacttacgtagacagtatcacatcactcttatgcatacataaagaggaaaaaaatgtttcctataactttgtcacagttagtctgactcttctgaataacttttttaatcccagtagtcaagctcctgtacttttgtaaaatatattaacagtgaattactagaaaatgggccatgttcttgtatattacagtgatgtcaattgctgataaattttctaactgcttactctcggataccgtacttgtctaagaactgaaaataattcacagactgatcccatgcccagtcctggccatgctttgagtggcTGTATTGGagcagaaaagccagggtggctcacctggggtgagaatgaggggggtgaatagtaagaggggtcgtgtaggtcttcttcaggatttgcttatactctgagtgaaatgggggactattttagagaattttTTTAAAGtgggttagaatttacgtacaataaagttcacccatgttagtgttcca

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