Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CHP1P2
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:160093398-160096221  UCSC
Coordinates (T2T) chr6:161339555-161342380  UCSC
Coordinates (hg19) chr6:160514430-160517253  UCSC
Strand +
Parental Sequence NM_007236.5
Parental seq. overlap 2153 bp
Parental seq. overlap (%) 66.1%
Genomic Region Intragenic (IGF2R)
Retrocopy Summary CHP1P2, located on chr6:160093398-160096221, is a retrocopy of the parental gene CHP1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CHP1
Full Name calcineurin like EF-hand protein 1
Also known as CHP|SLC9A1BP|SPAX9|Sid470p|p22|p24
Coordinate chr15:41231156-41281887
Strand +
Gene summary This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CHP1P2
Bonobo Pan paniscus CHP1P2
Gorilla Gorilla gorilla CHP1P1
Orangutan Pongo abelii CHP1P2
Gibbon Nomascus leucogenys CHP1P1
Green monkey Chlorocebus sabaeus CHP1P2
Crab-eating macaque Macaca fascicularis CHP1P1
Rhesus Macaca mulatta CHP1P1
Baboon Papio anubis CHP1P2
Golden snub-nosed monkey Rhinopithecus roxellana CHP1P2
Marmoset Callithrix jacchus CHP1P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CHP1P2
TGGAGGAGCTCCTGGCACAGTGATGGGGTCTCAGGCCTCCACCTTACTGCACGATGAAGAGTTTGAGGAGATCAAGAAGGAGACTGGCTTTTCCCACAGTCAAATCACACGTCTGTACAGCCGGTTCAGCAACCTGGACAAAGGAGAGAACAGGACGATTTCCAGGGGATTCCAGAACTTGCCATCAACCCAGTGGGGGACTGGATCATCAATGCCTTCCTTCCAGAGGGAGAGGACCAGGTAAACTTCCGTGGATTCCTGCAAACTCTGGCTCATTTCCAAACCATTGAGGATAATGAAAAGAGCAAAGTTGTGAATGGACCTGAACCACTCAACAGCCGAAGCAACAAACTGCAGTTTGCTTTTCGACTATATGATTTGGATAAAGATAACAAGATCTCTCGTGATGAGCTGTTAAGGGTGCTGTGCATGATGGTCCAAATAAATATCTCAGATAAGCAGCTGGGCAGTATCGCAGACAGGACCATTCAGGAGGCTGATCAGCATGGGGACAGTGCCATATCTTTATCACAGACTTTGCTAAGGTTTTGGAGAAGGTGGATGTAGAACAGAAAATGAGCATCTGATTTCTTCACTAAAGGACAGACAGCAAACTATTCCTTGCAGTCTAGTATTTAAGTACTGGAACTTGACAGTCCTCCTGTCCACCAGCCCTACCTCCACCCCATCATTCCCCTTCTCCCAAAGTACTACTGCTGTTGCATAACAACCCCAAATATGTTCTGTCAACACAAACCTGCTTTTGGTCTATAAACAGGGCGTTACAGAATGGTACACCCAGTCTATTTCTTCTCAGTATCCATTCGCCAGTTCTTCATTTATAAATATCGTCTTCCTCTGTTCTGCTGCTGAATGCCACACATCCATCCAGTCTGAGAAAGTAAGATAGGGAATCCTGCCGAGGAACAAGCCAGCAAAGCTCTTTCACTGGATGTAGACTGCACCTGCTGCCTTCCCTCTGGCGAGTCTGCCAGCATGCTTCTCCATCCTTTTTATATGTCCTTTGCTTCCCACTTCTGTGTACATTCAACATACTGTTCACGTAGTCATGCAGTCTTTCTGCTTTTTGTGAAGCCTCAGAATCTCCTCTGTTCTACTTGGCACCCCAAGCTATGCCTGGTATTGTATTTCTGACTTGGCTCGATAGTTCGGTGGTCTGGCAGTTTTTATCTACCTTCATTATTAAAAGGCCCTCTGGAGGCCCTCTGGGATGTTGCCTCTCCAGGAGCTTTTTGGTAACCAACACTTCTCTCGGGAGTATGAGATCATCCTCTGCACTCTTCTCTGTCATCAAAGGGCTGCTGGGTGGAGATATTCTTGAAAGGTGGCCTTGGTGAGAGGTGTGGAGTCAAGTCTTTTAGGTTGCTTGCCCACGTCACTCTACCTCTGGCCTCTGATTCTCAACTTTGTACCTATGGGGCGTCTCTTGTTAGTGCAGTGTTGACTATTCAAAAAGTAGCAATATGCCTGCAGATTTGCTTAGTCTTGGGACACGGTTACCACCAGAACGGCTGCTCAGACAATATGCTTGGGGACTTTCTCATGGCTTTTTGAACAAGGAGGCTGCGCACCCTGTGAAGCCTCCTGCATTCACACCTCTGCTGCATGGTTTATGCCTCAGTGTTATGTGCACTGGAATGCTTTTCACTATACGTTTCCAAGTTAGAAAGATTAGTGTTATGGAAGTGCCTAATGTATCCTAGTCCAAAATATTTAAAGATTGTTCTCTGTGTCTTGAAGTTTTGCACAAAATTCTTTATGAATTTTACACTTGGCAAATGTTAATGCTAGAAGCCATAGTCCGCTTCTTATACAAGTCCAAAGCGTTGACTGTTGTATCATTAGCTCCCTGGTTACACTGGTTTCCCAGCTCCTTGTGTAGACCACTGCTAATCCCTTAGAAACAAGAGGTCTGGCACTAGTAGCACAACCTAAGGTGGCATTCCAAGTCTTTAAGCAAGTCACAGCAACTTTTCTGCCAAAGTCAGCTTAGTTTAGACTTCAGTGAATCAGGCTGTTGCCATCCTAATGTATGTCTCTGTGAGTCTGTTCATTCACATATCTGCCGTTGGCTGATGGAAAGCTATTGAAGATGTGTACATAATTCTTTAGGAAGGGGATTGCTAAAAAATACACTGCAAAGCGATGGAAAACAGTGGAGAACAGGGGAGTAGCCAGGCTGGATGGCTCAAATATAAATGAATGAGGAATTCTTTATGAAGTGTCAGTTGGACTTTGTGATTGAGTGATGTAATACAGGAATTATATAGAAAGGGAAGAATATCTGATACTGATCTGTTAGATACTTCAGAGGCTCCTTGATTTGCATATTTAAAGTTCCTAAAATTGTAGCTTTTCCCTTCTTTTGGCTGTACAGCAGACTGTTTTaTACTCGTGGTTAAAACAAAA
>NM_007236.5
AGTGGAAACACTGCCCTCTCCCTTCTTGACCCCTAGCccttccttccctccctccttccctccTGTCGCCGTCTCTTCTGGCGCCGCTGCTCCCGGAGGAGCTCCCGGCACGGCGATGGGTTCTCGGGCCTCCACGTTACTGCGGGACGAAGAGCTCGAGGAGATCAAGAAGGAGACCGGCTTTTCCCACAGTCAAATCACTCGCCTCTACAGCCGGTTCACCAGCCTGGACAAAGGAGAGAATGGGACTCTCAGCCGGGAAGATTTCCAGAGGATTCCAGAACTTGCCATCAACCCACTGGGGGACCGGATCATCAATGCCTTCTTTCCAGAGGGAGAGGACCAGGTAAACTTCCGTGGATTCATGCGAACTTTGGCTCATTTCCGCCCCATTGAGGATAATGAAAAGAGCAAAGATGTGAATGGACCCGAACCACTCAACAGCCGAAGCAACAAACTGCACTTTGCTTTTCGACTATATGATTTGGATAAAGATGAAAAGATCTCCCGTGATGAGCTGTTACAGGTGCTACGCATGATGGTCGGAGTAAATATCTCAGATGAGCAGCTGGGCAGCATCGCAGACAGGACCATTCAGGAGGCTGATCAGGATGGGGACAGTGCCATATCTTTCACAGAATTTGTTAAGGTTTTGGAGAAGGTGGATGTAGAACAGAAAATGAGCATCCGATTTCTTCACTAAAGGAGACCAAACTGTTCCTTGCGGTCTAGTATTTAAGAACTGGAACTTGAAAGTCCTCCTTCTACCAACTCCACCTCCACCCCCTCATTCCCCTTCTCCCAAAGTACTACTGCTGTTGCATGACAACCCCAAATATGTTCTGTCAACACAAACCTGCCTTTGGTGTATAAACAGGGCATTACAGAATGGTACACCCTATATATTTCTGTTCAGTATCCATTCACTAGTTCTTCATTTATAAATATCATCTTCCCCATTCTGCTGCTGAATGCCACACATCCATCCAGTCTGAGAAAGTGAGAGAGGCAATCATGCCAAGAACAAGCCAGCAAAGCTCTTTCACCAGATGTAGACTGTAGCCCTGCTGCCTTCCCTCCAGCGAGTCTGCCAGCATGCTTCTTCATCCTTTTTATATGTTCTTTGCTTCCTACTTCCCTGTCTTCCAACATACTGTTCACTTACTCTGGCAGTCTTTCTGCTTTTCATTAAGCCTCAAAATCTCCTCTGTTCTACTTGGCACCACAAGCTATGTCCTATATATGTATTTCTGACTTGGCAGGATAGTTCAGGGGTCTGGCAGTTTTTATTTACCTTCATTATTAAATGGGCCTCTGGGATGTTGCCTCTTCAGGAGCTTTTTGGTAATCAATACTTCTCTCAGAAGTATGAGACCATCCTCTGCACTCTGCTCTGTCATCAAAGGCTGCTGGGTGGAGATACCCTTTTTGAAAGGTGGCCTTGGTGAGAGGTATGGAGCCAAGTCTTCTAGGTTGCTTGCCCACATCACTCTATCTCTGGCCTCTGATTCTCAACTTTGTACCTGTGTGGCTCCTCTTGTTAGTGCAATGTTGACTGTTGAAAAAGCAGCAGTATGCTTACAGGTTTGCTTAGTTTGGGGACACCGTTACCACCAGAATGGCTGCTCTGACAATATGCCTAGGGACTTTCTCATGGCTTTTATTTAATAAGGAGGCTGGGCACCCTATAAAGCCTCATGCATTCACACCTTTGCAGCATGGTTTATGCCTCAGTGTTATGTGCACTGGAATGTTTTCCACTTCACATTTCCAAGTAGAAATATTAGTGTTACGGAAGTGCCTAATATCCCAGTCCAAAtttttttttttttttttttttttttttgagacagagtcttgctctgtcacccaggctggagtgcagtggtgcgatcgctcactgcaacctcagcctcctggatttaagtgattctcctgcctcagcctcccaagtagctgggattacaggtgtgcaccaccatgcccggctaattttttgtatttttagtggagacagggtttcaccatgttggccaggctggtctcgaactcctgacctcgtgatccgcctgcctcagcctcccaaagtgctgggattacaggtgtgagccaccacgcctggccCCAGTCCAAAATATTTAAAGATTGTTTCCTTAGTGTCTTGAAGTTTTGCACAAAAttcttttttttgagatggagtctcactctgtcacccaggctggagtgcagtggcgtgatcttggctcactgcaacctctgcctcctgggttcaagcaattctcccacctcagcctcccaagtagctgggattacagacgtgtgccaccatacctgggtaatttttgcatttttagtggagagggagtttcaccatgttggccaggttggtcttgaactcctgacctcaggtgatcctcctgcctcggcctcccaaagtgctgggattacaggcatgagccaccgtgctcagccGCAAAATTCTTTATGAATTTTACACTTGGCAAATGTTAATGACGGAAGCCATAGTCTGCTCCTAATACATGTCCAAAGCATTGACTGTTGTGTCATTAGCTGCCTGGTTACATTAGCTCCCTGGCTTCTTGTTTAGACCACTGCTAATCCCTTAAAAACAAGAGGTCTGGCACTAGTAGCACAACCTAAGGTGGCATTACAGATCTTTGAGCGAGCCACAGCAACTTTTCTGCCAAGTCAGCTTAGTTTAGACTTCAGTGAATCAGGCTATTGCTATCCTAATGTATGTCTCTATGAGTGTATTTAGCCACACATCTGCCCTTGGTTGACTTTCTGACTCAttgcttgcttgcttgtttccttgcttTGGAAAACTATTGAAGATTGCTAAAAAATACCACTGCAAAGTGATGGAAAAGGGTGGAGAACAGGGGAGTAGCCAGGCTGGATGGCTCAAATATAAATGAATGAGGAATTCTTTATGAAGTATCAGTCAGATTTTATGATTAAGTGATGTAATATAGGAATTATGTAAAAGGGAAGAATGTCTGATACTGATCTATTAGAGAGGTACTTTAGAGGCTTCTTGATTGGCATAAAGTTCCTAAGGTTATAGATTTTCCCCCCTTTTGGCTGTATAGCAAAGTGTTTTAATCCACGGTTGTGCCTTATTGTTCCATTAAAATTGTATCTTCGATCCATCAATAAATACTTGTGGTTGAAACAAAA

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