Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name IGF2BP3P1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:166699360-166703088  UCSC
Coordinates (T2T) chr6:168077510-168081229  UCSC
Coordinates (hg19) chr6:167112848-167116576  UCSC
Strand -
Parental Sequence NM_006547.3
Parental seq. overlap 3553 bp
Parental seq. overlap (%) 82.5%
Genomic Region Intragenic (RPS6KA2)
Retrocopy Summary IGF2BP3P1, located on chr6:166699360-166703088, is a retrocopy of the parental gene IGF2BP3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name IGF2BP3
Full Name insulin like growth factor 2 mRNA binding protein 3
Also known as CT98|IMP-3|IMP3|KOC|KOC1|VICKZ3
Coordinate chr7:23310209-23470674
Strand -
Gene summary The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes IGF2BP3P1
Bonobo Pan paniscus IGF2BP3P1
Gorilla Gorilla gorilla IGF2BP3P1
Orangutan Pongo abelii IGF2BP3P1
Gibbon Nomascus leucogenys IGF2BP3P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>IGF2BP3P1
CTGGTGGATGCGTTTCGGTTGTAGCTAGGCTTTTTCTTTTCTTTCTCTTTTAAAACATATCTAGACAAGGAAAAACAAGCCTCGGATCTGATTTTTTGCTCCTCGTTCTTGTGCTTGGTTCTTACTGTGTTTGTGTATTTTAAAGGCGAGAAGACGAGGGGAACAAAACCAGCTGGATCCATCCATCACCGTGGGTGGTTTTAATTTTCGTTTTTCTCATTAATTTTTTTTAAACAACCATTCTTCACAATGAACAAACCGTATATCAGAAACCTCAGCGAGAACGCCGCCCCCTTGGACCTAGAAGGTATCTTGAAGGACGCCAAGATCCCCGTGTCGGGACCCTTCCTGGTGAAGATTGGCTACGCGTTCGTGGACTGCCCAGACGAGATCTGGGCCCTCAAGGCCATTGAGGCGCTTTCAGGTAAAATAGAACTGCACGGGAAACCCATAGAAGTTGAGCACTCGGTCCCAAAAAGGCAAAGGATTCGGAAACTTCAGATACGAAATATCCCTCCTCACTTACAGTGGGAGGTGCTGGATAGTTGACTAGTCCAGTATGGAGTGGTGGAGAGCTGTCAGCAAGTGAACACTGACTCGGAAACTGCAGTTGTAAATGTAACCTATTCCAGTAAGGACCAAgctagacaagcgctagacaagcactagacaaACTGAATGGATTTCAGTTAGAGAATTTCACCTTGAAAGTAGCCTATATCCCTGATGAAATGGCCACCCAGCAAAACCCCTTTCTGCAGCCCCGAGGTCGCCGGGGGCTTGGGCAGAGGGGCTCCTCAAGGCAGGGGTCTCCAGGATCCGTGTCCAAGCAGAAACCATGTGATTTGCCTCTGTGCCTGCTGGTTCCCACCCAATTTGTTGGAGCCATTATAGGAAAAGAAGGTGCCACCATTCGGAACATCACCAAACAGACCCAGTCTAAAATCGATGTCCACCGTAAAGAAAATGCAGGGGCTGCTGAGAAGTCGATTACTATCCTCTCTACTCCTGAAGGCACCTCTGCGGCTTGTAAGTCTATTCTGGAGATTATGCGTAAGGAAACTCAAGATGTAAAATTCACAGAAGAGATCCCCTTGAAGATTTTAGCTCAAAATAACTTTGTTGGCCGTCTTATTGGTAAAGAAGGAAGAAATCTTAAAAAAATTGAGCAAGACACAGACACTAAAATCACGATATCTCCATTGCAGGAACTGATGCAGTATAATCCAGAACACACCATTACAGCTAAAGGCAATGTTGAGACATGTGCCAAAGCTGAGGAAGAGATCATGAAGAAAATCAGGGAGCGTTAGGAAAATGATATCACTTCTATGATTTCAAGCACATTTAATTCCTGGATTAAATCTGAACGCCTTGGGTCTGTTCCCACCCACTTCAGGGATGCCACCTCCCACCTCAGGGCCCCCTTCAGCCATGACTCCTCCCTCCCCGCAGTCTGAGCAATCAGAATCCGAGACTGTTCATCTGTTTATCCCGGCTCTATCAGTCAGAGCCCTCATCAGCAAGCAGGGCCAGCACATCAAGCAGCTTTCTCGCTTTGCTGGAGCTTCAAGTAAGATTGCTCCAGTGGAAGCACCAGATGCTAAGGTGAGGATGGTGATGATCGCTGGATCACCAGAGGCTCGGTTCAAGGCTCAGGGAAGAATTATGGAAAAATGAAAGAAGAAAACTTCGTTAGTCCTAAAGAAGAGGTGAAACTTGAAGCTCATATCAGAGTGCCATCCTTTGCTGCTGGCAGTTACTGGAAAAGGAGGCAAAACGGTGAATGAACTTCAGAATTTGTCAAGTGCAGAAGTTGTTGTCCCTTGTGACCAGACACCTGATGAGAATGACCAAGTGGTTGTCAAAATAACTGGTCACTTCTATGCTTGCCAGGTTGCCCAGAGAAAAATTCAGGAAATTCTGACTCAGGTAAAGCAGCAGCAACAACAGAAGGCTCTGCAAAGTGGACCACCTCAGTCAAGACGGAAGTAAGGCTCAGGAAACAGCCCACCACGGAGGCAGATGCCAAACCAAAGACAGATTGCTTAACAAACAGACAGGCGCTGACCCCCTATCCAGAATCACATGCACAAGTTTTTACCTAGCCACTTGTTTCTGAGGACCAGGCAACTTTTGAACTCCTGTCTCTGTGAGAATGTGTACTTTATGCTCTCTGAAATGTATGACACCCAGCTTTAAAACAAACACACAAAAAAAGGGTGGCAGAGGGGGGAAAGAGAAGAGCTCTGCACTTCCCTTTGTTGTAGTCTCACAGTATAACAGATATTCTAATTATTCTTAATATTCCCCCATAATGCCAGAAATTGGCTTAATGATGCTTTCACTAAATTCATCAAATAGATTGTTCCTAAATCCAATTGTTAAAATTGGAGCAGAATAATTATTACAGGAACTTAAATGTTAAGCCATTAGCATGGAAAAACTGTTCTCAGTTTTATTTTTACTTAACACTAACATGAGTAACCTAAGGGAAGTGCTGAACGGTGTTGACAGGGGTATAAAACGTGCATTTTTACTCAACTACCTCGGGTATTCAGTAATACAATGAAAAGCAAAATTGTTCTTTTTTTTTTGAAAATTTTATATACTTTATAATGATAGAAGTCCAACCGTTTTTTAAAAAATAAATTTAAAATTTAACAGCAACAGCTAATAGGCAAATTAAGAATTTTACTTCTGGCTGGTGACAGTAAAGCTGGAAAATTAATTTCAGGGTTTTTTGAGGCTTTTGACACAGTTATGAGTTAAAAAAATCAAATGTTCAAAGATACAGAGCAGTGCCTTATATCTGGAGAGCAGCACTACCATTTATTCTTTCATTTATAGTTGAGAAAGTTTCTGATGGTACTAACAAAGTGGTGGCAGAAGATTTTGGAACGGCTGGTTTAAATGGCTTCAGGAGACTGCAGTTTTTTGTTTAGCTACATGATTGAATGCATAATAAATGCTTTGTGCTTTTGACTATCAATACCTAAAGAAAGTGCATCAATGAAGAGATGCAGGACTTTCAACTGATTGGCAAAAAGCAAGCTTTAGCTTGTCTTACAGGATGCTTAGTTTGCCAGTACACTTCAGACCAATGGGACAGTCATAGATGGTGTGACAGTGTTTAAAGGCAACAAAAGGCTACATTTCCATGTGGCCAGCACTGTCATGAGCCTCACTAAGCTATTTTGAAGATTTTTAAGCACTGATAAATTAAAAACAAAAAATTAGACTCCACCTAAAGTAGTAAAATATAGCAGGATTTCTGTATACTGTGCAATCAGTTCTTTGGAAAAAAAAGTCAAAAGATAGAGAATACAAGACAAGTTTTTGGGATATAATTCGAATGACTGTGAAAACATATGACCTTTGATACCGAACTCATTTGCTCACTCCTTAACTTGACAGCAAAGCCCAGTATGTACAATTGTGTTGGGTGTGGGTGGTCTCCAAGGCCATGCTGCTCTCTGAATTGATTTTGAGTTTTGTTGGTAAGATGATCACAGTCATGTTACACTGATCTAAAGACTTGTATATATCACCCTTTAAAAAGATCACTCTGCCTCATTCTTATTTCAAGATGAATTTCTATACAGACTAGATAATGTTTTTCTGAAGATCATATCAATTAGACATTTTGAAAATGATTTAAAGTGTTTTCCTTAATGTTCTCAGAAAGCAAGTTTTTTTTGTAGTTTTATCc
>NM_006547.3
AGTGTGATATTTTCACAGTCCGCTGGCCGAAGCCAAAGGGGTTGGGAAGGAAGAGACAAAAAGTAGTTTTTtcccctcctcctcctcctttctcttgctaatcccgcctcctcctAAGACTTAGGAAGACTGGTGGATGCGTTTGGGTTGTAGCTAGGCTTTTTCTTTTCTTTCTCTTTTAAAACACATCTAGACAAGGAAAAAACAAGCCTCGGATCTGATTTTTCACTCCTCGTTCTTGTGCTTGGTTCTTACTGTGTTTGTGTATTTTAAAGGCGAGAAGACGAGGGGAACAAAACCAGCTGGATCCATCCATCACCGTGGGTGGTTTTAATTTTTCGTTTTTTCTCGTTATTTTTTTTTAAACAACCACTCTTCACAATGAACAAACTGTATATCGGAAACCTCAGCGAGAACGCCGCCCCCTCGGACCTAGAAAGTATCTTCAAGGACGCCAAGATCCCGGTGTCGGGACCCTTCCTGGTGAAGACTGGCTACGCGTTCGTGGACTGCCCGGACGAGAGCTGGGCCCTCAAGGCCATCGAGGCGCTTTCAGGTAAAATAGAACTGCACGGGAAACCCATAGAAGTTGAGCACTCGGTCCCAAAAAGGCAAAGGATTCGGAAACTTCAGATACGAAATATCCCGCCTCATTTACAGTGGGAGGTGCTGGATAGTTTACTAGTCCAGTATGGAGTGGTGGAGAGCTGTGAGCAAGTGAACACTGACTCGGAAACTGCAGTTGTAAATGTAACCTATTCCAGTAAGGACCAAGCTAGACAAGCACTAGACAAACTGAATGGATTTCAGTTAGAGAATTTCACCTTGAAAGTAGCCTATATCCCTGATGAAATGGCCGCCCAGCAAAACCCCTTGCAGCAGCCCCGAGGTCGCCGGGGGCTTGGGCAGAGGGGCTCCTCAAGGCAGGGGTCTCCAGGATCCGTATCCAAGCAGAAACCATGTGATTTGCCTCTGCGCCTGCTGGTTCCCACCCAATTTGTTGGAGCCATCATAGGAAAAGAAGGTGCCACCATTCGGAACATCACCAAACAGACCCAGTCTAAAATCGATGTCCACCGTAAAGAAAATGCGGGGGCTGCTGAGAAGTCGATTACTATCCTCTCTACTCCTGAAGGCACCTCTGCGGCTTGTAAGTCTATTCTGGAGATTATGCATAAGGAAGCTCAAGATATAAAATTCACAGAAGAGATCCCCTTGAAGATTTTAGCTCATAATAACTTTGTTGGACGTCTTATTGGTAAAGAAGGAAGAAATCTTAAAAAAATTGAGCAAGACACAGACACTAAAATCACGATATCTCCATTGCAGGAATTGACGCTGTATAATCCAGAACGCACTATTACAGTTAAAGGCAATGTTGAGACATGTGCCAAAGCTGAGGAGGAGATCATGAAGAAAATCAGGGAGTCTTATGAAAATGATATTGCTTCTATGAATCTTCAAGCACATTTAATTCCTGGATTAAATCTGAACGCCTTGGGTCTGTTCCCACCCACTTCAGGGATGCCACCTCCCACCTCAGGGCCCCCTTCAGCCATGACTCCTCCCTACCCGCAGTTTGAGCAATCAGAAACGGAGACTGTTCATCTGTTTATCCCAGCTCTATCAGTCGGTGCCATCATCGGCAAGCAGGGCCAGCACATCAAGCAGCTTTCTCGCTTTGCTGGAGCTTCAATTAAGATTGCTCCAGCGGAAGCACCAGATGCTAAAGTGAGGATGGTGATTATCACTGGACCACCAGAGGCTCAGTTCAAGGCTCAGGGAAGAATTTATGGAAAAATTAAAGAAGAAAACTTTGTTAGTCCTAAAGAAGAGGTGAAACTTGAAGCTCATATCAGAGTGCCATCCTTTGCTGCTGGCAGAGTTATTGGAAAAGGAGGCAAAACGGTGAATGAACTTCAGAATTTGTCAAGTGCAGAAGTTGTTGTCCCTCGTGACCAGACACCTGATGAGAATGACCAAGTGGTTGTCAAAATAACTGGTCACTTCTATGCTTGCCAGGTTGCCCAGAGAAAAATTCAGGAAATTCTGACTCAGGTAAAGCAGCACCAACAACAGAAGGCTCTGCAAAGTGGACCACCTCAGTCAAGACGGAAGTAAAGGCTCAGGAAACAGCCCACCACAGAGGCAGATGCCAAACCAAAGACAGATTGCTTAACCAACAGATGGGCGCTGACCCCCTATCCAGAATCACATGCACAAGTTTTTACCTAGCCAGTTGTTTCTGAGGACCAGGCAACTTTTGAACTCCTGTCTCTGTGAGAATGTATACTTTATGCTCTCTGAAATGTATGACACCCAGCTTTAaaacaaacaaacaaacaaacaaaaaaaGGGTGGGGGAGGGAGGGAAAGAGAAGAGCTCTGCACTTCCCTTTGTTGTAGTCTCACAGTATAACAGATATTCTAATTCTTCTTAATATTCCCCCATAATGCCAGAAATTGGCTTAATGATGCTTTCACTAAATTCATCAAATAGATTGCTCCTAAATCCAATTGTTAAAATTGGATCAGAATAATTATCACAGGAACTTAAATGTTAAGCCATTAGCATAGAAAAACTGTTCTCAGTTTTATTTTTACCTAACACTAACATGAGTAACCTAAGGGAAGTGCTGAATGGTGTTGGCAGGGGTATTAAACGTGCATTTTTACTCAACTACCTCAGGTATTCAGTAATACAATGAAAAGCAAAATTGTTCCTTTTTTTTGAAAATTTTATATACTTTATAATGATAGAAGTCCAACCGTTTTTTAAAAAATAAATTTAAAATTTAACAGCAATCAGCTAACAGGCAAATTAAGATTTTTACTTCTGGCTGGTGACAGTAAAGCTGGAAAATTAATTTCAGGGTTTTTTGAGGCTTTTGACACAGTTATTAGTTAAATCAAATGTTCAAAAATACGGAGCAGTGCCTAGTATCTGGAGAGCAGCACTACCATTTATTCTTTCATTTATAGTTGGGAAAGTTTTTGACGGTACTAACAAAGTGGTCGCAGGAGATTTTGGAACGGCTGGTTTAAATGGCTTCAGGAGACTTCAGTTTTTTGTTTAGCTACATGATTGAATGCATAATAAATGCTTTGTGCTTCTGACTATCAATACCTAAAGAAAGTGCATCAGTGAAGAGATGCAAGACTTTCAACTGACTGGCAAAAAGCAAGCTTTAGCTTGTCTTATAGGATGCTTAGTTTGCCACTACACTTCAGACCAATGGGACAGTCATAGATGGTGTGACAGTGTTTAAACGCAACAAAAGGCTACATTTCCATGGGGCCAGCACTGTCATGAGCCTCACTAAGCTATTTTGAAGATTTTTAAGCACTGATAAATTAAAAAAAAAAAATTAGACTCCACCTTAAGTAGTAAAGTATAACAGGATTTCTGTATACTGTGCAATCAGTTCTTTGAAAAAAAAGTCAAAAGATAGAGAATACAAGAAAAGTTTTTGGGATATAATTTGAATGACTGTGAAAACATATGACCTTTGATAACGAACTCATTTGCTCACTCCTTGACAGCAAAGCCCAGTACGTACAATTGTGTTGGGTGTGGGTGGTCTCCAAGGCCACGCTGCTCTCTGAATTGATTTTTTGAGTTTTGTTTGTAAGATGATCACAGTCATGTTACACTGATCTAAAGGACATATATATAACCCTTTAAAAAAAAAATCACTGCCTCATTCTTATTTCAAGATGAATTTCTATACAGACTAGATGTTTTTCTGAAGATCAATTAGACATTTTGAAAATGATTTAAAGTGTTTTCCTTAATGTTCTCTGAAAACAAGTTTCTTTTGTAGTTTTAACCAAAAAAGTGCCCTTTTTGTCACTGGATTCTCCTAGCATTCATGATTTTTTTTTCATACAATGAATTAAAATTGCTAAAATCATGGACTGGCTTTCTGGTTGGATTTCAGGTAAGATGTGTTTAAGGCCAGAGCTTTTCTCAGTATTTGATTTTTTTCCCCAATATTTGATTTTTTAAAAATATACACATAGGTGCTGCATTTATATCTGCTGGTTTAAATTCTGTCATATTTCACTTCTAGCCTTTTAGTATGGCAAATCATATTTTACTTTTACTTAAGCATTTGTAATTTGGAGTATCTGGTACTAGCTAAGAAATAATTCTATAATTGAGTTTTGTACTCACCATATATGGATCATTCCTCATGTATAATGTGCCCCAAATGCAGCTTCATTTTCCAGATACCTTGACGCAGAATAAATTTTTTCATCATTTAGGTGCA

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