Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CDCA7P1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:27268105-27269778  UCSC
Coordinates (T2T) chr6:27136937-27138610  UCSC
Coordinates (hg19) chr6:27235884-27237557  UCSC
Strand +
Parental Sequence NM_031942.5
Parental seq. overlap 1330 bp
Parental seq. overlap (%) 46.5%
Genomic Region Intergenic
Retrocopy Summary CDCA7P1, located on chr6:27268105-27269778, is a retrocopy of the parental gene CDCA7. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CDCA7
Full Name cell division cycle associated 7
Also known as ICF3|JPO1
Coordinate chr2:173354872-173368997
Strand +
Gene summary This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CDCA7P1
Bonobo Pan paniscus CDCA7P1
Gorilla Gorilla gorilla CDCA7P1
Orangutan Pongo abelii CDCA7P1
Gibbon Nomascus leucogenys CDCA7P2
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CDCA7P1
TGCTCTCCGCGTGCCGCAAAAGGATCTCAGAGTAAAGACGATCTTAAATTCGATATGTGAAGTTGATTCCCATGGAAACCTCGTCATCCTCTCATGACAATTATGACAGCTTTGCTTCTGATAATTTTGCAAACACGAGGCTTCAGTCAGTCCAGGAAGGCTGCTGGACCAGCAGCCAGTGCAGACACTCTGGACTTCTCAGGCAGGCGATGAAGTTTCCAGGGCGAAACACCAGGGGAGCAGCCAATAAAAAAGCAGAGTACCCCAAACCCTCAAGGAATTCTATGACTGGTTCCAATTCCGATTCAGAAGATGAAAGTGCCATGAAGAGGAAAGGGCTTGAAATATAAAGCAAAACAAAGCAATGCTTGTAAAACGCATGTCAGTATTAGAAGCTTCTCTGGTTTGTTCCCCGGAAGACATTCCCCGCCAGGCCCCAACTCACAATCAAGGAGACCCCAAGGTAAACATTCCTGGATGTTTCTTCAAGGAGACATTCTGAATGGAGAGAGCTCGGCCTCTTAGAGGTCAAGGTCAGGATCCTCGGGTCCCTTGGCGCTCTACCTACGGAAGAGAAGGAAGAAAAGACAGAGGCTAAGTACATGTTGGTGAGAAAGAGGAAGATTGTGGACGGCTACATGAACGAAGTTGAGATGCTCAGAAATCGTCCCGCCAGATCACCCATGATCCTTCCACATATAATTCGGCCACCGGAAGAAATTACAGAGGAAGGTTTGGAGAACATCTGCAGCAACTCTCAAGAGAAGATATATAACCGTTCGCTGGGTTCTATTTGTCATCAATGCCGCCAGAAAACTATTGTTATCAAACAAACTGCAGAAACCCAGACTGTTGGGGCTTTCAAGGCCTGTTCTGCGGCCCCGACCTTAGAAACCCTTGTGGTGAAGAGGTCAGGAATACTCTGCTGGATGCGAACTGGCATTGTCCGCCTTGTCGAGGCCGTGCAACTGCAGTTTCCGCTCGCAGCGAGATAGACTGTGGGAAACTGGGGTCCTTGAATATTTAGCCAAATACAATGGCTTTGGGAATGTGCATGCTTACTTGAAAAGTCTGAAACAGGAATTTGAAATGCAAGCATAATATTGGAAAATTCACTGCCTGTCTTCCACTTCTCAAATCTCTCTTGCTGAAGTTTTCAATTTTGTCATTGCTTGAAACCTGAATTAAGAATCTTGGTGATCAGTCTGTTTTATAAGAAACTTCCATaCCTTCCATCAAGAATCTTGACAATCAGCCTCTTTATAAGAAGCTCCAATCAAGATAAATCTCAGTAGAGACATGTGTTTCTGGAGCATCACTAAACGAATATTGCTGGCTATACTTTCCCCTCCTACAGTTTTCTCCTCTGCTCCCCACAACCTCCAATTCATAGTACCCTTTTCTCTTTCCAATGGTCCTCTCCCCCTGCTTAGTTTCTGAAGTCTTTTTAAATGACAATTTTATGAAAGCATATTTGATTTAGTTGCAGTTGAAATAGCCCTGCAGTCCACTCATGAAACCTAAGCACTTAAAAACACAGTAGTAGTATTAATTAACTATATCTATTGAATTTCAGAGAACAGCCCTCTAACTTGTTTATGCAAAAAC
>NM_031942.5
gctgctgctgctcctcctgctgtgggaccgctgaccgcgcggctgctCCGCTCTCCCCGCTCCAAGCGCCGATCTGGGCACCCGCCACCAGCATGGACGCTCGCCGCGTGCCGCAGAAAGATCTCAGAGTAAAGAAGAACTTAAAGAAATTCAGATATGTGAAGTTGATTTCCATGGAAACCTCGTCATCCTCTGATGACAGTTGTGACAGCTTTGCTTCTGATAATTTTGCAAACACGAAACCTAAATTCAGGTCAGATATCAGTGAAGAACTGGCAAATGTTTTTTATGAGGACTCTGATAATGAATCTTTCTGCGGCTTTTCAGAAAGTGAGGTGCAAGATGTATTAGACCATTGTGGATTTTTACAGAAACCAAGGCCAGATGTCACTAACGAACTGGCCGGTATTTTTCATGCCGACTCTGACGATGAATCATTTTGCGGTTTCTCAGAGAGTGAGATACAAGATGGAATGAGGCTGCAGTCAGTTCGGGAAGGCTGTAGGACCCGCAGCCAGTGCAGGCACTCTGGACCTCTCAGGGTGGCGATGAAGTTTCCAGCGCGGAGTACCAGGGGAGCAACCAACAAAAAAGCAGAGTCCCGCCAGCCCTCAGAGAATTCTGTGACTGATTCCAACTCCGATTCAGAAGATGAAAGTGGAATGAATTTTTTGGAGAAAAGGGCTTTAAATATAAAGCAAAACAAAGCAATGCTTGCAAAACTCATGTCTGAATTAGAAAGCTTCCCTGGCTCGTTCCGTGGAAGACATCCCCTCCCAGGCTCCGACTCACAATCAAGGAGACCGCGAAGGCGTACATTCCCGGGTGTTGCTTCCAGGAGAAACCCTGAACGGAGAGCTCGTCCTCTTACCAGGTCAAGGTCCCGGATCCTCGGGTCCCTTGACGCTCTACCCATggaggaggaggaggaagaggataagtacatgttggtgagaaagaggaagaCCGTGGATGGCTACATGAATGAAGATGACCTGCCCAGAAGCCGTCGCTCCAGATCATCCGTGACCCTTCCGCATATAATTCGCCCAGTGGAAGAAATTACAGAGGAGGAGTTGGAGAACGTCTGCAGCAATTCTCGAGAGAAGATATATAACCGTTCACTGGGCTCTACTTGTCATCAATGCCGTCAGAAGACTATTGATACCAAAACAAACTGCAGAAACCCAGACTGCTGGGGCGTTCGAGGCCAGTTCTGTGGCCCCTGCCTTCGAAACCGTTATGGTGAAGAGGTCAGGGATGCTCTGCTGGATCCGAACTGGCATTGCCCGCCTTGTCGAGGAATCTGCAACTGCAGTTTCTGCCGGCAGCGAGATGGACGGTGTGCGACTGGGGTCCTTGTGTATTTAGCCAAATATCATGGCTTTGGGAATGTGCATGCCTACTTGAAAAGCCTGAAACAGGAATTTGAAATGCAAGCATAATATCTGGAAAATTTGCTGCCTGCCTTCTACTTCTCAAATCTTTCTTGTAAAAGTTTCCAATTTTTTCACTGAAACCTGAGTTAAAAATCTTGATGATCAGCCTGTTTCATAAGAAACTCCAATCAAGTTAATCTTAGCAGACATGTGTTTCTGGAGCATCACAGAAGGTATATTGCTAGTTACACTTTGCCCTCCTGCAGTTTCTTCTCTGCTCCCAACCCCCATCTCACAGCATCCCCCTCTATTTCCAATGCTCCTCTCCAACCGCTTAGTTTCTGAATTTCTTTTAAATTACAGTTTTATGAAAGCATATTTTATTTACTTGGTGTTGAAATAGCCCTCATAAAACCTAAGCACTTGGAAACACAATAATAGTATTAACTAACTAGATCTATTGAATTTCAGAGAAGAGCCTTCTAACTTGTTTACACAAAAACGAGTATGATTTAGCATTCATACTAGTTGAAATTTTTAATAGAATCAAGGCACAAAAGTCTTAAAACCATGTGGAAAAATTAGGTAATTATTGCAGATTGATGTCTCTCAATCCCATGTATTGCGCTTATGTTACAAGTTGTTGTCACAGTTGAGACTTAATTTCTCCTAATTTCTTCTGCCCGAAGGGTAAGTGGTGCGTCCAGCTTACACAATCATAATTCAAAGGTTGGTGGGCAATGTAATACTTAATTAAAATAATGATGGAAGAGCTATCTGGAGATTATGAGTAAGCTGATTTGAATTTTCAGTATAAAACTTTAGTATAATTGTAGTTTGCAAAGTTTATTTCAGTTCACATGTAAGGTATTGCAAATAAATTCTTGGACAATTTTGTATGGAAACTTGATATTAAAAACTAGTCTGTGGTTCTTTGCAGTTTCTTGTAAATTTATAAACCAGGCACAAGGTTCAAGTTTAGATTTTAAGCACTTTTATAACAATGATAAGTGCCTTTTTGGAGATGTAACTTTTAGCAGTTTGTTAACCTGACATCTCTGCCAGTCTAGTTTCTGGGCAGGTTTCCTGTGTCAGTATTCCCCCTCCTCTTTGCATTAATCAAGGTATTTGGTAGAGGTGGAATCTAAGTGTTTGTATGTCCAATTTACTTGCATATGTAAACCATTGCTGTGCCATTCAATGTTTGATGCATAATTGGACCTTGAATCGATAAGTGTAAATACAGCTTTTGATCTGTAATGCTTTTATACAAAAGTTTATTTTAATAATAAAATGTTTGTTCTAACTTGTCTGCTTTTTTAAAAATAATCTTACTGTACTTAATTCTAATTTTTTCCTCATATTTAAATAAAAGGCCATTTCCACCTTTTCTAAAAAA

Publications

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