Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name GPR89P
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:27736574-27738497  UCSC
Coordinates (T2T) chr6:27606269-27608192  UCSC
Coordinates (hg19) chr6:27704353-27706276  UCSC
Strand -
Parental Sequence XM_011509908.2
Parental seq. overlap 1723 bp
Parental seq. overlap (%) 85.5%
Genomic Region Intergenic
Retrocopy Summary GPR89P, located on chr6:27736574-27738497, is a retrocopy of the parental gene GPR89A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name GPR89A
Full Name G protein-coupled receptor 89A
Also known as GPHR|GPR89|GPR89B|SH120|UNQ192
Coordinate chr1:145607987-145670977
Strand +
Gene summary GPR89A is a nearly identical copy of the GPR89B gene (MIM 612806).[supplied by OMIM, Jun 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes GPR89AP1
Bonobo Pan paniscus GPR89AP1
Gorilla Gorilla gorilla LOC101128637P1
Gibbon Nomascus leucogenys GPR89AP1
Green monkey Chlorocebus sabaeus GPR89AP1
Crab-eating macaque Macaca fascicularis GPR89AP1
Rhesus Macaca mulatta GPR89AP1
Golden snub-nosed monkey Rhinopithecus roxellana GPR89AP1
Orangutan Pongo abelii Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>GPR89P
CGCAGCTTGATGGCGTCAGGCTGACGAGCCGCAGTCCCTACGGCTGCACCTGGGCGAAGGCCGCCTGTGTGAGAGGCCGGTGGCCCCAGCGTGCCGCGGCCTTGGAAGTGGGAAATGGAGGCAGGAGCCCTCCCTACACTTCACCATAGGCTTCCTGATTGATTCCAGCATCGTGATTACCTCCCAGATACTATTTTTTTTTAATTTGGGTGGCTTTTCTTCATGTGCCAATTGTTTAAGAACTATGAGGTGCGTCAGTATGTTGTACAGGTGATCTTCTCTGTGACGTTTGCATTTTCTTGCACTATGTTTGAGCTCATCATCTTTGAAATCTTTGGAGTATTGAGTAGCAGCTGTCGTTATTTTTACTGGAAATTGAACCTAGGTGTAATTCTGCTGATTCTGGTTTTCATGGTGCGTTTTTAAACTGGCTATTTTATTGTGAGCAACATCCGACTACTTTTGTCTCCTCTGTCTTAGTGCATAAACAACGACTGCTTTTTTCCTGTCTCTTGTGGTTGACCTTTATCTGTTTTTTCTGGAAACTAGGAGATTCCTTTCCCATTCTCAGCCCAAAACATGGGATCTTATCCATAGAACAGCTCATCAGCTGGGTTGGTGTGATTGGAGTTACTCTCATGGCCCTCCTTTCTGGATTTGGTGCCGTCTACTGCACATACACTTTGATGTCTTATTTCCTCAGGAATGTGACTGACACAGATATTCTAGCCCTGGAACAGCGACTGCTCCAAACCATGGATATGATCATAACCACAAAGAAAAGGATGGCAATGGCACAGAGAACGATGTTCCAGAAAGGGGAGGTGCATAACAAACCATCAGGATTCTGGGGAATGATAGAAAGTATTACCACTTACTCAACAGGAAGTGGATGCTTTGGAAGAACTAAGCAGGCAGCTTTTTCTGAAAACAGCTGATCTGTACGCTACCAAGGAGAGAACAGAATACTCCAAAACCTTCAAAAGGAAATATTTCAATTTTCTGGGTTACTTTTTCTCTATTTACTGTGTTTGAAAAATTTTCATGGCACCATCAACATTGCTTTTGATCGAGTTGGGAAAATGGATCCTGTCACAAGAGGCGTTGAGATCACTGTGAATTATCTGGGAATCCAGTGTGATGTGAAATTTTGGTCCCAACACATTTCCTCCATTCTTGTTGGAATAATCATCGCCACATCCATCAGAGGATTGCTCATACCACGTTCTTTTATGCCATCTCTAGCAGTAAGTCCTCCAGTGTCAATGTCCTGCTATTAGCACAGATAATGGGCATGTACTTTGTCTCCTCTGCGCTTCTAATCTGAATGAGTATGCCTCTAGAATATGCACCATAATTACCGAAGTCCTTGGAGAACTGCAGTTCAATTTCTGTTACCATTGGTTTGATGTGATCTTCCTGGTCAGCAGTCTCTCTAGCATAGTGTTTCTCTATTTGGCTCACTAACAGGCACCAGAGAAGCATATGACACCTTGAACTTAGGGCTACTACAGACTGTTAGAGGCCAGTGGTCTCAAAATTTAGATATGAAAGGGGAAAAAAATGGAGGGGACCAGGGTCTAACATTTTATAAACAAACAAAATGCTGTGGTAGCATTTTTTACCTCTAGCATCCTCTTTCCTACTCAGGTGATACTGTGATCACGAGTAGCATCAGCTAGAACATGAGAGAGAGCAGTAACTCAAGGCAATACTCAGCAGAGAGCATCCTATGTGGACCTGAGGCTGGTGCAATGGCGGAGAGGAACCGAAAAACTAAGAGGGAAAAATACACCGGAACTCTGGGGCAAGAGATGTCTATGGTAGCTGGGCCAAACACATAGGATATCCATTTTCAGGTTCACATGGAGGTGGTCATAGCTTTCCCTTGAGATTGACTGTCATGAAAATCAGAGATTGTAAT
>XM_011509908.2
CGCAGCTTGATGGCGTCGGGCTGGAGAGCCGCAGTCCCGGCTGCAGCACCTGGGAGAAGGCAGACCGTGTGAGGGGGCCTGTGGCCCCAGCGTGCTGTGGCCTCGGGGAGTGGGAAGTGGAGGCAGGAGCCTTCCTTACACTTCGCCATGAGTTTCCTCATCGACTCCAGCATCATGATTACCTCCCAGataaccttgcctcgtacttactcaacaaaagtgaagccaaaagATACTATTTTTTGGATTTGGGTGGCTTTTCTTCATGCGCCAATTGTTTAAAGACTATGAGATACGTCAGTATGTTGTACAGGTGATCTTCTCCGTGACGTTTGCATTTTCTTGCACCATGTTTGAGCTCATCATCTTTGAAATCTTAGGAGTATTGAATAGCAGCTCCCGTTATTTTCACTGGAAAATGAACCTGTGTGTAATTCTGCTGATCCTGGTTTTCATGGTGCCTTTTTACATTGGCTATTTTATTGTGAGCAATATCCGACTACTGCATAAACAACGACTGCTTTTTTCCTGTCTCTTATGGCTGACCTTTATGTATTTCTTCTGGAAACTAGGAGATCCCTTTCCCATTCTCAGCCCAAAACATGGGATCTTATCCATAGAACAGCTCATCAGCCGGGTTGGTGTGATTGGAGTGACTCTCATGGCTCTTCTTTCTGGATTTGGTGCTGTCAACTGCCCATACACTTACATGTCTTACTTCCTCAGGAATGTGACTGACACGGATATTCTAGCCCTGGAACGGCGACTGCTGCAAACCATGGATATGATCATAAGCAAAAAGAAAAGGATGGCAATGGCACGGAGAACAATGTTCCAGAAGGGGGAAGTGCATAACAAACCATCAGGTTTCTGGGGAATGATAAAAAGTGTTACCACTTCAGCATCAGGAAGTGAAAATCTTACTCTTATTCAACAGGAAGTGGATGCTTTGGAAGAATTAAGCAGGCAGCTTTTTCTGGAAACAGCTGATCTATATGCTACCAAGGAGAGAATAGAATACTCCAAAACCTTCAAGGGGAAATATTTTAATTTTCTTGGTTACTTTTTCTCTATTTACTGTGTTTGGAAAATTTTCATGGCTACCATCAATATTGTTTTTGATCGAGTTGGGAAAACGGATCCTGTCACAAGAGGCATTGAGATCACTGTGAATTATCTGGGAATCCAATTTGATGTGAAGTTTTGGTCCCAACACATTTCCTTCATTCTTGTTGGAATAATCATCGTCACATCCATCAGAGGATTGCTGATCACTCTTACCAAGTTCTTTTATGCCATCTCTAGCAGTAAGTCCTCCAATGTCATTGTCCTGCTATTAGCACAGATAATGGGCATGTACTTTGTCTCCTCTGTGCTGCTGATCCGAATGAGTATGCCTTTAGAATACCGCACCATAATCACTGAAGTCCTTGGAGAACTGCAGTTCAACTTCTATCACCGTTGGTTTGATGTGATCTTCCTGGTCAGCGCTCTCTCTAGCATACTCTTCCTCTATTTGGCTCACAAACAGGCACCAGAGAAGCAAATGGCACCTTGAACTTAAGCCTACTACAGACTGTTAGAGGCCAGTGGTTTCAAAATTTAGATATAAGAGGGGGGAAAAATGGAACCAGGGCCTGACATTTTATAAACAAACAAAATGCTATGGTAGCATTTTTCACCTTCATAGCATACTCCTTCCCCGTCAGGTGATACTATGACCATGAGTAGCATCAGCCAGAACATGAGAGGGAGAACTAACTCAAGACAATACTCAGCAGAGAGCATCCCGTGTGGATATGAGGCTGGTGTAGAGGCGGAGAGGAGCCAAGAAACTAAAGGTGAAAAATACACTGGAACTCTGGGGCAAGACATGTCTATGGTAGCTGAGCCAAACACGTAGGATTTCCGTTTTAAGGTTCACATGGAAAAGGTTATAGCTTTGCCTTGAGATTGACTCATTAAAATCAGAGACTGTAACACTTT

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